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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Specification URL Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
cisTEM
 
Resource Report
Resource Website
50+ mentions
cisTEM (RRID:SCR_016502) cisTEM data processing software, image processing software, software application, software resource Software to process cryo-EM images of macromolecular complexes and obtain high-resolution 3D reconstructions from them. data, processing, high, resolution, electron, cryo, macroscopy, single, particle, averaging, image, macromolecule, high, resolution, 3D, bio.tools is listed by: bio.tools
is listed by: Debian
Howard Hughes Medical Institute DOI:10.7554/eLife.35383 Open source, Trial available biotools:cistem https://bio.tools/cistem SCR_016502 computational imaging system for Transmission Electron Microscopy 2026-09-12 12:58:40 67
kallisto
 
Resource Report
Resource Website
100+ mentions
kallisto (RRID:SCR_016582) data analysis software, data processing software, software application, software resource Software tool for quantifying abundances of transcripts from RNA-Seq data or target sequences using high-throughput sequencing reads. bio.tools is listed by: Debian
is listed by: bio.tools
works with: sleuth
works with: kb_python
PMID:27043002 Free, Available for download, Freely available biotools:kallisto https://pachterlab.github.io/kallisto/download.html, https://bio.tools/kallisto, https://sources.debian.org/src/kallisto/ SCR_016582 kallisto v0.43.1 2026-09-12 12:58:41 148
Pavian
 
Resource Report
Resource Website
10+ mentions
Pavian (RRID:SCR_016679) analysis service resource, data analysis service, production service resource, service resource, software resource, web application Software R package for interactive analysis of metagenomics classification results with a special focus on infectious disease diagnosis. Used for analyzing and visualization of metagenomics classification results from classifiers such as Kraken, Centrifuge and MetaPhlAn. Provides an alignment viewer for validation of matches to a particular genome. interactive, analysis, metagenomics, classification, result, infectious, disease, diagnosis, data, visualization, bio.tools is listed by: Debian
is listed by: bio.tools
is related to: Centrifuge Classifier
NHGRI R01 HG006677;
NIGMS R01 GM083873;
U. S. Army Research Office W911NF1410490
DOI:10.1101/084715 Free, Freely available biotools:pavian https://fbreitwieser.shinyapps.io/pavian/, https://bio.tools/pavian SCR_016679 2026-09-12 12:58:43 33
Centrifuge Classifier
 
Resource Report
Resource Website
10+ mentions
Centrifuge Classifier (RRID:SCR_016665) data analysis software, data processing software, sequence analysis software, software application, software resource Software for rapid and sensitive classification of metagenomic sequences. Used for the classification of DNA sequences from microbial samples and analysis of large metagenomics data sets on conventional desktop computers. classification, large, metagenomic, sequence, DNA, microbial, sample, analysis, data, desktop, computer, bio.tools is listed by: bio.tools
is listed by: Debian
is listed by: OMICtools
is related to: Pavian
has parent organization: Center for Computational Biology at JHU
NHGRI R01 HG006677;
NIGMS R01 GM083873;
NSF ABI1356078;
U. S. Army Research Office W911NF1410490
DOI:10.1101/gr.210641.116 Free, Available for download, Freely available biotools:centrifuge, OMICS_12217 https://github.com/infphilo/centrifuge, https://bio.tools/centrifuge, https://sources.debian.org/src/centrifuge/ SCR_016665 2026-09-12 12:58:43 10
TB PORTALS
 
Resource Report
Resource Website
10+ mentions
TB PORTALS (RRID:SCR_016594) consortium, data or information resource, data repository, disease-related portal, organization portal, portal, service resource, storage service resource, topical portal Web based open access platform for global drug resistant tuberculosis data sharing and analysis. The NIAID TB Portals program and consortium of clinicians and scientists from countries with a heavy burden of TB, especially drug resistant TB, to collect TB data. collect, data, sharing, analysis, tuberculosis, global, bio.tools is listed by: NIAID
is listed by: bio.tools
is listed by: Debian
tuberculosis NIH DOI:10.1128/JCM.01013-17 Free, Freely available r3d100013925, biotools:TB_Portals https://bio.tools/TB_Portals, https://doi.org/10.17616/R31NJN8L SCR_016594 2026-09-12 12:58:42 20
NMRProcFlow
 
Resource Report
Resource Website
10+ mentions
NMRProcFlow (RRID:SCR_016592) data processing software, data visualization software, software application, software resource Software as graphical and interactive tool dedicated to 1D spectra processing for NMR-based metabolomics. NMR, metabolomics, data, viewer, spectra, processing, graphical, interface, bio.tools uses: R Project for Statistical Computing
is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
French National Infrastructure in Metabolomics and Fluxomics DOI:10.1007/s11306-017-1178-y Free, Available for download, Freely available biotools:nmrprocflow, SCR_022777 https://github.com/INRA/NMRProcFlow, https://bio.tools/nmrprocflow, https://github.com/inra/nmrprocflow SCR_016592 Nuclear Magnetic Resonance PROcessing FLOW, Nuclear Magnetic Resonance Processing Flow 2026-09-12 12:58:42 29
CheckM
 
Resource Report
Resource Website
100+ mentions
CheckM (RRID:SCR_016646) data analysis software, data processing software, software application, software resource, software toolkit Software tool to assess the quality of microbial genomes recovered from isolates, single cells, and metagenomes by using a broader set of marker genes specific to the position of a genome within a reference genome tree and information about the collocation of these genes. assess, quality, microbial, genome, recovered, bio.tools is listed by: Debian
is listed by: bio.tools
DOI:10.1101/gr.186072.114 Free, Available for download, Freely available biotools:checkm https://github.com/Ecogenomics/CheckM, https://bio.tools/checkm SCR_016646 2026-09-12 12:58:42 238
Genotyping
 
Resource Report
Resource Website
10+ mentions
Genotyping (RRID:SCR_016645) data access protocol, data analysis software, data processing software, sequence analysis software, software application, software resource, web service Web tool to identify the genotype of a viral sequence. A window is slid along the query sequence and each window is compared by BLAST to each of the reference sequences for a particular virus. identify, genotype, viral, sequence, bio.tools is listed by: bio.tools
is listed by: Debian
has parent organization: NCBI
works with: NCBI BLAST
Free, Freely available biotools:ncbi_genotyping https://bio.tools/ncbi_genotyping SCR_016645 2026-09-12 12:58:42 40
Libra
 
Resource Report
Resource Website
Libra (RRID:SCR_016608) data analysis software, data analytics software, data processing software, sequence analysis software, software application, software resource Hadoop based tool for massive comparative metagenomics analysis. Compute the similarity between metagenomic samples. gene, distance, matrix, computation, k-mer-based, sequence, comparison, Hadoop, metagenomic, sample, bio.tools is listed by: bio.tools
is listed by: Debian
NSF 1640775 Free, Available for download, Freely available biotools:Libra_k-mer https://bio.tools/Libra_k-mer SCR_016608 2026-09-12 12:58:42 0
KAT
 
Resource Report
Resource Website
10+ mentions
KAT (RRID:SCR_016741) KAT data analysis software, data processing software, software application, software resource, software toolkit Software that generates, analyses and compares k-mer spectra produced from sequence files. Used to quality control NGS datasets and genome assemblies. generate, analyse, compare, k-mer, spectra, sequence, file, quality, control, NGS, dataset, genome, assembly, bio.tools is listed by: Debian
is listed by: bio.tools
BBSRC DOI:10.1093/bioinformatics/btw663 Free, Available for download, Freely available biotools:kat http://www.earlham.ac.uk/kat-tools, https://bio.tools/kat SCR_016741 K-mer Analysis Toolkit 2026-09-12 12:58:44 21
BBmap
 
Resource Report
Resource Website
500+ mentions
BBmap (RRID:SCR_016965) alignment software, data processing software, image analysis software, software application, software resource, software toolkit Software tool as a short read aligner for DNA and RNA seq data. Used for large genomes with millions of scaffolds. Can align reads from Illumina, PacBio, 454, Sanger, Ion Torrent, Nanopore. Fast and accurate, particularly with highly mutated genomes or reads with long indels, even whole gene deletions over 100kbp long. It has no upper limit to genome size or number of contigs. Written in Java, can run on any platform. Joint Genome Institute, short, read, aligner, DNA, RNA, sequencing, data, large, genome, scaffold, mutated, long, indel is listed by: Bestus Bioinformaticus Tools
is listed by: Debian
is related to: University of California at Berkeley; Berkeley; USA
Free, Available for download, Freely available https://jgi.doe.gov/data-and-tools/bbtools/bb-tools-user-guide/bbmap-guide/, https://sources.debian.org/src/bbmap/ SCR_016965 2026-09-12 12:58:46 915
CCTOP
 
Resource Report
Resource Website
10+ mentions
CCTOP (RRID:SCR_016963) CCTOP analysis service resource, data access protocol, production service resource, service resource, software resource, web service Web application providing transmembrane topology prediction. Server incorporates topology information from existing experimental and computational sources using the probabilistic framework of hidden Markov model. Provides the option to precede the topology prediction with signal peptide prediction and transmembrane globular protein discrimination. Given the amino acid sequence of a putative α helical transmembrane protein, CCTOP predicts its topology i.e. localization of membrane spanning regions and orientation of segments between them. transmembrane, topology, prediction, signal, peptide, globular, protein, discrimination, amino, acid, sequence, region, orientation, segment, bio.tools is listed by: Debian
is listed by: bio.tools
works with: PDBTM
works with: Topology Data Bank of Transmembrane Proteins
works with: TopDom
Hungarian Scientific Research Fund PMID:25943549 Free, Freely available biotools:cctop https://bio.tools/cctop SCR_016963 CCTOP, Consensus Constrained TOPology 2026-09-12 12:58:46 31
Illuminating the Druggable Genome
 
Resource Report
Resource Website
50+ mentions
Illuminating the Druggable Genome (RRID:SCR_016924) IDG consortium, data or information resource, data repository, organization portal, portal, service resource, storage service resource Program to improve understanding of properties and functions of proteins that are currently unannotated within three most commonly drug protein families: targeted G-protein coupled receptors, ion channels, and protein kinases. Includes Data and Resource Generating Centers (DRGC), Knowledge Management Center (KMC), and Resource Dissemination and Outreach Center (RDOC). understudied, target, protein, G protein, coupled, receptor, ion, channel, kinase, bio.tools is recommended by: National Library of Medicine
is listed by: NIDDK Information Network (dkNET)
is listed by: bio.tools
is listed by: Debian
NIH Common Fund biotools:pharos https://pharos.nih.gov/, https://bio.tools/pharos, https://darkmatter.ucsf.edu/about https://druggablegenome.net SCR_016924 Pharos, Illuminating the Druggable Genome, IDG, Illuminating Druggable Genome 2026-09-12 12:58:46 64
Thunder STORM
 
Resource Report
Resource Website
10+ mentions
Thunder STORM (RRID:SCR_016897) ThunderSTORM data analysis software, data processing software, software application, software resource, software toolkit Software tool for automated processing, analysis, and visualization of data acquired by single molecule localization microscopy methods such as PALM and STORM. ImageJ interactive and modular plugin for SMLM data analysis and super-resolution imaging. automated, processing, analysis, visualization, data, acquired, single, molecule, localization, microscopy, SMLM, imaging, bio.tools is listed by: Debian
is listed by: bio.tools
is a plug in for: ImageJ
Charles University ;
Czech Science Foundation ;
European Regional Development Fund ;
European Social Fund
PMID:24771516 Free, Available for download, Freely available biotools:thunderstorm https://bio.tools/thunderstorm SCR_016897 2026-09-12 12:58:45 48
CRISPR-P
 
Resource Report
Resource Website
10+ mentions
CRISPR-P (RRID:SCR_016941) analysis service resource, data access protocol, production service resource, service resource, software resource, web service Web tool for synthetic single-guide RNA design of CRISPR-system in plants. Allows to search for high specificity Cas9 target sites within DNA sequences of interest, which also provides off-target loci prediction for specificity analyses and marks restriction enzyme cutting site to every sgRNA for further convenient in experiment. synthetic, single, RNA, CRISP, plant, Cas9, target, DNA, sequence, analysis, restriction, enzyme, sgRNA, bio.tools is listed by: Debian
is listed by: bio.tools
Fundamental Research Funds for the Central Universities ;
National Basic Research Program of China ;
Program for New Century Excellent Talents in University
PMID:24719468 Free, Freely available biotools:CRISPR-P https://bio.tools/CRISPR-P SCR_016941 CRISPR-P 2.0, Clustered Regularly Interspaced Short Palindromic Repeats P, CRISPR P 2026-09-12 12:58:46 42
ascat
 
Resource Report
Resource Website
10+ mentions
ascat (RRID:SCR_016868) ASCAT data analysis software, data processing software, software application, software resource Software R package to infer tumor purity, ploidy and allele-specific copy number profiles. It is platform and species independent, and works for both Illumina and Affymetrix SNP arrays, as well as for massively parallel sequencing data. allele, specific, copy, number, analysis, tumor, purity, ploidy, sequencing, data, bio.tools is listed by: Debian
is listed by: bio.tools
PMID:20837533 Free, Available for download, Freely available BioTools:ascat, biotools:ascat https://github.com/VanLoo-lab/ascat, https://www.crick.ac.uk/research/labs/peter-van-loo/software, https://bio.tools/ascat, https://sources.debian.org/src/r-other-ascat/ SCR_016868 ASCAT 3.0, ASCAT 2.0, ASCAT 4.0, ASCAT 1.0, Allele-Specific Copy Number Analysis of Tumors, Allele Specific Copy Number Analysis of Tumors 2026-09-12 12:58:45 42
EMAN
 
Resource Report
Resource Website
100+ mentions
EMAN (RRID:SCR_016867) EMAN data processing software, image processing software, software application, software resource Software suite for processing data from transmission electron microscopes. Used in supercomputing facilities as a test application for large-scale computing. Used for single particle reconstruction, helical reconstruction, 2-D crystallography and whole-cell tomography. image, processing, data, transmission, electron, microscope, single, particle, reconstruction, helical, 2D, whole, cell, tomography, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
is listed by: SoftCite
NIH PMID:16859925 Free, Available for download, Freely available biotools:eman https://bio.tools/eman https://blake.bcm.edu/emanwiki/EMAN1 SCR_016867 EMAN1, EMAN2 2026-09-12 12:58:45 107
clusterProfiler
 
Resource Report
Resource Website
10000+ mentions
clusterProfiler (RRID:SCR_016884) data analysis software, data processing software, data visualization software, software application, software resource Software R package for statistical analysis and visualization of functional profiles for genes and gene clusters. data, statistical, analysis, visualization, gene, cluster, bio.tools is listed by: Bioconductor
is listed by: Debian
is listed by: bio.tools
is related to: R Project for Statistical Computing
2007 Chang-Jiang Scholars Program ;
Fundamental Research Funds for the Central Universities ;
Guangdong Natural Science Research Grant ;
National 973 Projects of China ;
National Natural Science Foundation of China
PMID:22455463 Free, Available for download, Freely available biotools:clusterprofiler https://github.com/GuangchuangYu/clusterProfiler, https://guangchuangyu.github.io/software/clusterProfiler/, https://bio.tools/clusterprofiler SCR_016884 Cluster Profiler 2026-09-12 12:58:45 13465
QuickNII
 
Resource Report
Resource Website
10+ mentions
QuickNII (RRID:SCR_016854) QuickNII data processing software, image analysis software, image processing software, registration software, software application, software resource Histological brain section series aligner to volumetric atlases. Software tool for user guided affine registration (anchoring) of 2D experimental image data, typically high resolution microscopic images, to 3D atlas reference space, facilitating data integration through standardized coordinate systems. Part of the QUINT workflow. section, series, aligner, volumetric, 3D, atlas, reference, space, anchoring, data, image, microscopic, standardized, coordinate, system, bio.tools is used by: BICCN
is listed by: Debian
is listed by: bio.tools
is listed by: EBRAINS
is related to: LocaliZoom
is related to: Allen Institute for Brain Science
has parent organization: University of Oslo; Oslo; Norway
European Union Horizon 2020 Framework Programme for Research and Innovation under the Framework Partnership Agreement PMID:31141518 Free, Available for download, Freely available biotools:QuickNII https://quicknii.readthedocs.io; https://bio.tools/QuickNII, https://github.com/Tevemadar/QuickNII SCR_016854 2026-09-12 12:58:45 42
Gigwa
 
Resource Report
Resource Website
1+ mentions
Gigwa (RRID:SCR_017080) analysis service resource, application programming interface, biomaterial analysis service, data access protocol, data analysis software, data distribution software, data management software, data processing software, material analysis service, production service resource, service resource, software application, software resource, web service Web tool to explore genotyping metdata by filtering it on basis of variant features, including functional annotations and matching genotype patterns. May be deployed on workstation or as data portal. Allows to feed MongoDB database with VCF, PLINK or HapMap files and provides interface to filter data in real time. Used to export filtered data into formats and features connectivity with online genomic tools and with standalone software such as FlapJack or IGV. Gigwa hosted datasets are interoperable via two standard REST APIs such GA4GH and BrAPI. metadata, genotyping, filter, variant, functional, annotation, pattern, bio.tools is listed by: Debian
is listed by: bio.tools
UMR DIADE and Agropolis Fundation PMID:27267926 Free, Freely available biotools:Gigwa https://github.com/SouthGreenPlatform/Gigwa2, https://bio.tools/Gigwa SCR_017080 GIGWA, GIGWA2, Genotype Investigator for Genome Wide Analysis 2026-09-12 12:58:48 2

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