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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Specification URL Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
Rainbow
 
Resource Report
Resource Website
10+ mentions
Rainbow (RRID:SCR_002724) data analysis software, data processing software, sequence analysis software, software application, software resource Software developed to provide an ultra-fast and memory-efficient solution to clustering and assembling short reads produced by RAD-seq. software, tool, clustering, assembling, short, read, restriction, site, DNA, sequence, analysis, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: SourceForge
PMID:22942077
DOI:10.1093/bioinformatics/bts482
Free, Freely available, Available for download SCR_015992, OMICS_03722, biotools:rainbow https://bio.tools/rainbow, https://sources.debian.org/src/bio-rainbow/ SCR_002724 RAD-seq: Restriction-site Associated DNA sequencing, Bio-rainbow, RAD-seq 2026-08-29 11:21:11 41
rDock
 
Resource Report
Resource Website
100+ mentions
rDock (RRID:SCR_002838) software resource A fast and versatile Open Source docking software program that can be used to dock small molecules against proteins and nucleic acids. standalone software is listed by: OMICtools
has parent organization: SourceForge
PMID:24722481 Free, Freely available, Available for download OMICS_03835 SCR_002838 2026-08-29 11:21:20 122
VariationHunter
 
Resource Report
Resource Website
10+ mentions
VariationHunter (RRID:SCR_004865) VariationHunter software resource A software tool for discovery of structural variation in one or more individuals simultaneously using high throughput technologies. structural variation, genome, next-generation sequencing is listed by: OMICtools
is related to: SPLITREAD
has parent organization: Simon Fraser University; British Columbia; Canada
has parent organization: SourceForge
PMID:22048523
PMID:20529927
OMICS_00328 SCR_004865 VariationHunter-CommonLaw 2026-08-29 11:22:02 12
Pythia
 
Resource Report
Resource Website
50+ mentions
Pythia (RRID:SCR_004952) software resource Pythia is an open source thermodynamically oriented primer design python module. Pythia can be used in two ways. 1. Executable binaries only: under windows with cygwin and python 2.5 (built with mingw, that comes with the cygwin release). These executables allow the user to index DNA files for primer specificity search, design one primer pair per region, and tile regions with PCR amplicons. 2. A python module: under windows with cygwin, python2.5, numpy, swig, and mingw, or under linux with python2.4 or later, numpy, and swig (everything but numpy should be pre-installed on a normal linux system). The module gets you everything that the binaries get you, in a more pythonic framework. This package also includes modules for computing DNA binding and folding energies using the partition function approach with publicly available thermodynamic data. Usage documentation is in the downloads. has parent organization: SourceForge PMID:19528077 nlx_91969 SCR_004952 2026-08-29 11:22:13 50
cortex var
 
Resource Report
Resource Website
1+ mentions
cortex var (RRID:SCR_005081) cortex_var software resource A tool for genome assembly and variation analysis from sequence data. You can use it to discover and genotype variants on single or multiple haploid or diploid samples. If you have multiple samples, you can use Cortex to look specifically for variants that distinguish one set of samples (eg phenotype=X, cases, parents, tumour) from another set of samples (eg phenotype=Y, controls, child, normal). cortex_var features * Variant discovery by de novo assembly - no reference genome required * Supports multicoloured de Bruijn graphs - have multiple samples loaded into the same graph in different colours, and find variants that distinguish them. * Capable of calling SNPs, indels, inversions, complex variants, small haplotypes * Extremely accurate variant calling - see our paper for base-pair-resolution validation of entire alleles (rather than just breakpoints) of SNPs, indels and complex variants by comparison with fully sequenced (and finished) fosmids - a level of validation beyond that demanded of any other variant caller we are aware of - currently cortex_var is the most accurate variant caller for indels and complex variants. * Capable of aligning a reference genome to a graph and using that to call variants * Support for comparing cases/controls or phenotyped strains * Typical memory use: 1 high coverage human in under 80Gb of RAM, 1000 yeasts in under 64Gb RAM, 10 humans in under 256 Gb RAM genome assembly, variation analysis, sequence, variation, genotype variant, haploid, diploid, snp, indel, inversion, variant, haplotype, de novo assembly, genotyping, variant-calling, population analysis, population assembly is listed by: OMICtools
has parent organization: SourceForge
has parent organization: Wellcome Trust Centre for Human Genetics
PMID:22231483 GNU General Public License, v3, Acknowledgement requested OMICS_00056 SCR_005081 cortex_var - for variant and population assembly 2026-08-29 11:22:06 3
Bambus
 
Resource Report
Resource Website
Bambus (RRID:SCR_005068) Bambus software resource Software for scaffolding to address some of the challenges encountered when analyzing metagenomes. Scaffolding represents the task of ordering and orienting contigs by incorporating additional information about their relative placement along the genome. While most other scaffolders are closely tied to a specific assembly program, Bambus accepts the output from most current assemblers and provides the user with great flexibility in choosing the scaffolding parameters. In particular, Bambus is able to accept contig linking data other than specified by mate-pairs. Such sources of information include alignment to a reference genome (Bambus can directly use the output of MUMmer), physical mapping data, or information about gene synteny. scaffolding is listed by: OMICtools
has parent organization: SourceForge
PMID:21926123 Open unspecified license OMICS_01432 http://sourceforge.net/apps/mediawiki/amos/index.php?title=Bambus SCR_005068 Bambus 2, Bambus 2.0 2026-08-29 11:22:06 0
G-BLASTN
 
Resource Report
Resource Website
G-BLASTN (RRID:SCR_005062) G-BLASTN software resource A GPU-accelerated nucleotide alignment tool based on the widely used NCBI-BLAST. It can produce exactly the same results as NCBI-BLAST, and it also has very similar user commands. It also supports a pipeline mode, which can fully utilize the GPU and CPU resources when handling a batch of medium to large sized queries. parallel computation 4, blast, alignment, nucleotide, gpu, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
is related to: NCBI BLAST
has parent organization: Hong Kong Baptist University; Hong Kong; China
has parent organization: SourceForge
Hong Kong Baptist University; Hong Kong; China FRG2/11-12/158;
NVIDIA
PMID:24463183 Free OMICS_02263, biotools:g-blastn http://sourceforge.net/projects/gblastn/, https://bio.tools/g-blastn SCR_005062 2026-08-29 11:22:22 0
VFS
 
Resource Report
Resource Website
1+ mentions
VFS (RRID:SCR_005138) VFS software resource A versatile high-throughput sequencing (HTS) tool for discovering viral integration events and reconstruct fusion transcripts at single-base resolution. It combines soft-clipping information, read-pair analysis, and targeted de novo assembly to discover and annotate viral-human fusion events. A simple yet effective empirical statistical model is used to evaluate the quality of fusion breakpoints. Minimal user defined parameters are required. ubuntu, debian, high-throughput sequencing, virus, reconstruct, fusion transcript, transcript, integration, fusion, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: SourceForge
has parent organization: Chinese University of Hong Kong; Hong Kong; China
PMID:23314323 GNU General Public License, v3 OMICS_00224, biotools:viralfusionseq https://bio.tools/viralfusionseq SCR_005138 ViralFusionSeq, ViralFusionSeq (VFS) 2026-08-29 11:22:08 1
COVA
 
Resource Report
Resource Website
50+ mentions
COVA (RRID:SCR_005175) COVA software resource A variant annotation and comparison tool for next-generation sequencing. It annotates the effects of variants on genes and compares those among multiple samples, which helps to pinpoint causal variation(s) relating to phenotype. next-generation sequencing, variant annotation, variant, annotation, gene, genetic variation, phenotype is listed by: OMICtools
has parent organization: SourceForge
OMICS_00171 SCR_005175 COVA - Comparison of variants and functional annotation, Comparison of variants and functional annotation 2026-08-29 11:22:16 60
QuRe
 
Resource Report
Resource Website
1+ mentions
QuRe (RRID:SCR_005209) QuRe software resource A software program for viral quasispecies reconstruction, specifically developed to analyze long read (>100 bp) next-generation sequencing (NGS) data. The software performs alignments of sequence fragments against a reference genome, finds an optimal division of the genome into sliding windows based on coverage and diversity and attempts to reconstruct all the individual sequences of the viral quasispecies--along with their prevalence--using a heuristic algorithm, which matches multinomial distributions of distinct viral variants overlapping across the genome division. QuRe comes with a built-in Poisson error correction method and a post-reconstruction probabilistic clustering, both parameterized on given error rates in homopolymeric and non-homopolymeric regions. next-generation sequencing, virus, long read, reconstruction is listed by: OMICtools
has parent organization: SourceForge
OMICS_00230 SCR_005209 qure - software for viral quasispecies reconstruction from next-gen seq. data 2026-08-29 11:22:17 6
UnoSeq
 
Resource Report
Resource Website
1+ mentions
UnoSeq (RRID:SCR_005116) UnoSeq software library, software resource, software toolkit A Java library to analyze next generation sequencing data and especially perform expression profiling in organisms where no well-annotated reference genome exists. java, expression profile, next generation sequencing is listed by: OMICtools
has parent organization: SourceForge
PMID:20194116 OMICS_01296 SCR_005116 UnoSeq - Expression profiling with next generation sequencing without a reference genome 2026-08-29 11:22:15 1
ORMAN
 
Resource Report
Resource Website
1+ mentions
ORMAN (RRID:SCR_005188) ORMAN software resource A software tool for resolving multi-mappings within an RNA-Seq SAM file. bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: SourceForge
PMID:24130305 OMICS_01284, biotools:orman https://bio.tools/orman SCR_005188 ORMAN : Optimal Resolution of Ambiguous RNA-Seq Multi-mappings in the Presence of Novel Isoforms 2026-08-29 11:22:09 4
SeqAnt
 
Resource Report
Resource Website
1+ mentions
SeqAnt (RRID:SCR_005186) SeqAnt analysis service resource, data analysis service, production service resource, service resource, software resource A free web service and open source software package that performs rapid, automated annotation of DNA sequence variants (single base mutations, insertions, deletions) discovered with any sequencing platform. Variant sites are characterized with respect to their functional type (Silent, Replacement, 5' UTR, 3' UTR, Intronic, Intergenic), whether they have been previously submitted to dbSNP, and their evolutionary conservation. Annotated variants can be viewed directly on the web browser, downloaded in a tab delimited text file, or directly uploaded in a Browser Extended Data (BED) format to the UCSC genome browser. SeqAnt further identifies all loci harboring two or more coding sequence variants that help investigators identify potential compound heterozygous loci within exome sequencing experiments. In total, SeqAnt resolves a significant bottleneck by allowing an investigator to rapidly prioritize the functional analysis of those variants of interest. annotation, dna sequence variant, single base mutation, insertion, deletion, sequencing, mutation, variant, sequence variant, perl, sequence, genome is listed by: OMICtools
has parent organization: Emory University; Georgia; USA
has parent organization: SourceForge
PMID:20854673 GNU General Public License, v2 OMICS_00182 SCR_005186 SeqAnt - Sequence Annotator 2026-08-29 11:22:23 2
Centroid Trajectory Analysis
 
Resource Report
Resource Website
10+ mentions
Centroid Trajectory Analysis (RRID:SCR_006331) CeTrAn data analysis software, data processing software, software application, software resource Open source software written in R that tracks a single animal walking in a homogenous environment (Buritrack) and analyzes its trajectory. It extracts eleven metrics and includes correlation analyses and a Principal Components Analysis (PCA). It was designed to be easily customized to personal requirements. In combination with inexpensive hardware, these tools can readily be used for teaching and research purposes. Buritrack is a program to track individual Drosophila fruit flies online with any camera as they walk in Buridan's paradigm. The program extracts the coordinate locations of the fly and stores them in a text file. trajectory, buridan, principal components analysis, correlation analysis, buridan's paradigm, locomotion, software, tracking, drosophila has parent organization: Free University of Berlin; Berlin; Germany
has parent organization: SourceForge
Swiss National Science Foundation PA00P3_124141;
EPSRC EP/F030673/1
PMID:22912692 Open source, Available for Mac and PC, Source code available for download nlx_152033 SCR_006331 CeTrAn: centroid trajectory analysis 2026-08-29 11:22:34 11
SpliceGrapher
 
Resource Report
Resource Website
10+ mentions
SpliceGrapher (RRID:SCR_006657) SpliceGrapher software resource Software that predicts alternative splicing patterns and produces splice graphs that capture in a single structure the ways a gene''s exons may be assembled. It enhances gene models using evidence from next-generation sequencing and EST alignments. is listed by: OMICtools
has parent organization: SourceForge
PMID:22293517 OMICS_01266 SCR_006657 2026-08-29 11:22:41 22
POLGUI - Matlab Polhemus Interface
 
Resource Report
Resource Website
1+ mentions
POLGUI - Matlab Polhemus Interface (RRID:SCR_006752) POLGUI software resource An interface between MATLAB and the Polhemus Fastrak digitizer used to digitize fiducial locations and scalp EEG electrode locations. There are 5 versions all of which work under MATLAB R14 (on both linux and windows platforms), # polgui_ver1_r14 : works with 1 receiver (stylus pen) # polgui_ver2_r14 : works with 2 receivers (including the pen) # polgui_ver3_r14 : works with 3 receivers(including the pen) # polgui_ver4_r14 : works with 4 receivers (including the pen) # polgui_ver5_r14 : Generic version which works with 1/2/3/4 receivers (WARNING: Ver 5 might be buggy; not fully tested) Requirements: MATLAB R14 (Linux/Windows) eeg, meg, electrocorticography, linux, matlab, microsoft, magnetic resonance, posix/unix-like, win32 (ms windows), windows is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC)
has parent organization: SourceForge
BSD License nlx_155915 http://www.nitrc.org/projects/polgui SCR_006752 POLGUI - Matlab GUI for Polhemus Fastrak 2026-08-29 11:22:41 5
BMDExpress
 
Resource Report
Resource Website
10+ mentions
BMDExpress (RRID:SCR_006823) BMDExpress data analysis software, data processing software, software application, software resource Bioinformatics tool used to analyze microarray dose-response data. The analysis provides benchmark dose estimates at which different cellular processes are altered in toxicogenomic experiments. bioinformatics, microarray, software, toxicogenomics is related to: The Hamner Institute for Health Sciences: BMDExpress and The multiple-path particle dosimetry
has parent organization: SourceForge
MIT License nlx_152743 SCR_006823 2026-08-29 11:22:45 38
mubiomics
 
Resource Report
Resource Website
1+ mentions
mubiomics (RRID:SCR_006785) mubiomics software resource A set of scripts (mostly python) for processing reads generated by the Roche 454 or Illumina next-gen sequencing platforms. Included are quality control, read demultiplexing and microbiome characterisation scripts for use with usearch, pplacer and RDP classifier. is listed by: OMICtools
has parent organization: SourceForge
OMICS_01059 SCR_006785 mubiomics - Scripts for processing next-gen sequencing data 2026-08-29 11:22:51 4
Qudaich
 
Resource Report
Resource Website
Qudaich (RRID:SCR_006775) Qudaich software resource A software package for local sequence alignment for next-generation sequencing (NGS) data. It generates the pairwise local alignments between a query dataset against a database. The main design purpose of qudaich is to focus on datasets from next generation sequencing. These the datasets generally have hundreds of thousand sequences or more, and so, the input database should contain large number of sequences. Qudaich is flexible and its algorithmic structure imposes no restriction on the absolute limit of the acceptable read length, but the current version of qudaich allow read length <2000 bp. Qudaich can be used to align DNA, translated DNA and protein sequences. next-generation sequencing, alignment is listed by: OMICtools
has parent organization: SourceForge
OMICS_00678 SCR_006775 Queries and unique database alignment inferred by clustering homologs 2026-08-29 11:22:51 0
Adverse Event Ontology
 
Resource Report
Resource Website
Adverse Event Ontology (RRID:SCR_006807) AEO controlled vocabulary, data or information resource, ontology AEO represents the Adverse Event Ontology, a community-driven ontology developed to standardize and integrate data on biomedical adverse events (e.g., vaccine adverse events) and support computer-assisted reasoning. The AEO also can be found in BioPortal, http://bioportal.bioontology.org/ontologies/45534?p=terms has parent organization: SourceForge nlx_44108 SCR_006807 2026-08-29 11:22:52 0

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