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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Specification URL Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
refgenie
 
Resource Report
Resource Website
1+ mentions
refgenie (RRID:SCR_017574) data management software, service resource, software application, software resource Software tool to organize, retrieve, and share genome analysis resources. Reference genome assembly asset manager. In addition to genome indexes, can manage any files related to reference genomes, including sequences and annotation files. Includes command line interface and server application that provides RESTful API, so it is useful for both tool development and analysis. Organize, retrive, share, genome, analysis, reference, assembly, asset, manager, sequence, annotation, file, command, line, interface, bio.tools is listed by: Debian
is listed by: bio.tools
DOI:10.1101/698704 Free, Available for download, Freely available biotools:Refgenie https://bio.tools/Refgenie SCR_017574 reference genome manager 2026-08-29 11:25:44 7
Centrifuge Classifier
 
Resource Report
Resource Website
10+ mentions
Centrifuge Classifier (RRID:SCR_016665) data analysis software, data processing software, sequence analysis software, software application, software resource Software for rapid and sensitive classification of metagenomic sequences. Used for the classification of DNA sequences from microbial samples and analysis of large metagenomics data sets on conventional desktop computers. classification, large, metagenomic, sequence, DNA, microbial, sample, analysis, data, desktop, computer, bio.tools is listed by: bio.tools
is listed by: Debian
is listed by: OMICtools
is related to: Pavian
has parent organization: Center for Computational Biology at JHU
NHGRI R01 HG006677;
NIGMS R01 GM083873;
NSF ABI1356078;
U. S. Army Research Office W911NF1410490
DOI:10.1101/gr.210641.116 Free, Available for download, Freely available biotools:centrifuge, OMICS_12217 https://github.com/infphilo/centrifuge, https://bio.tools/centrifuge, https://sources.debian.org/src/centrifuge/ SCR_016665 2026-08-29 11:25:20 10
PaVE
 
Resource Report
Resource Website
100+ mentions
PaVE (RRID:SCR_016599) PaVE analysis service resource, data analysis service, data or information resource, database, production service resource, service resource, software resource, web application Collection of curated papillomavirus genomic sequences, accompanied by web-based sequence analysis tools. Database and web applications support the storage, annotation, analysis, and exchange of information. data, curated, papilloma, virus, genomic, sequence, analysis, storage, annotation, FASEB list is listed by: NIAID NIAID ZIA AI001071 PMID:28053164 Open source SCR_016599 PapillomaVirus Episteme, Papillomavirus Episteme 2026-08-29 11:25:50 156
BLASTClust
 
Resource Report
Resource Website
50+ mentions
BLASTClust (RRID:SCR_016641) data analysis software, data processing software, sequence analysis software, software application, software resource Software tool as a program within the standalone BLAST package used to cluster either protein or nucleotide sequences. Used to make non redundant sequence sets. cluster, protein, nucleotide, sequence, pairwise, match, sequence is listed by: SoftCite
has parent organization: NCBI
works with: NCBI BLAST
Free, Freely available SCR_016641 2026-08-29 11:25:19 94
Genotyping
 
Resource Report
Resource Website
10+ mentions
Genotyping (RRID:SCR_016645) data access protocol, data analysis software, data processing software, sequence analysis software, software application, software resource, web service Web tool to identify the genotype of a viral sequence. A window is slid along the query sequence and each window is compared by BLAST to each of the reference sequences for a particular virus. identify, genotype, viral, sequence, bio.tools is listed by: bio.tools
is listed by: Debian
has parent organization: NCBI
works with: NCBI BLAST
Free, Freely available biotools:ncbi_genotyping https://bio.tools/ncbi_genotyping SCR_016645 2026-08-29 11:25:20 40
Open Reading Frame Finder
 
Resource Report
Resource Website
1000+ mentions
Open Reading Frame Finder (RRID:SCR_016643) ORF finder analysis service resource, data analysis software, data processing software, production service resource, sequence analysis software, service resource, software application, software resource Software tool to search for open reading frames (ORFs) in the DNA sequence. The program returns the range of each ORF, along with its protein translation. Used to search newly sequenced DNA for potential protein encoding segments, verify predicted protein. Limited to the subrange of the query sequence up to 50 kb long. search, open, reading, frame, DNA, sequence, ORF, protein, translation, data, encoding, segment, verify uses: BLASTP
has parent organization: NCBI
Free, Available for download, Freely available SCR_016643 Open Reading Frame finder, Open Reading Frame Finder 2026-08-29 11:25:50 1955
Libra
 
Resource Report
Resource Website
Libra (RRID:SCR_016608) data analysis software, data analytics software, data processing software, sequence analysis software, software application, software resource Hadoop based tool for massive comparative metagenomics analysis. Compute the similarity between metagenomic samples. gene, distance, matrix, computation, k-mer-based, sequence, comparison, Hadoop, metagenomic, sample, bio.tools is listed by: bio.tools
is listed by: Debian
NSF 1640775 Free, Available for download, Freely available biotools:Libra_k-mer https://bio.tools/Libra_k-mer SCR_016608 2026-08-29 11:25:50 0
dCAS
 
Resource Report
Resource Website
dCAS (RRID:SCR_016612) dCAS software resource, web application Web tool to import raw cDNA sequences, clean sequences, build sequence contigs, perform SignalP analysis, BLAST contigs against numerous BLAST databases, and view the results. Automates large scale cDNA sequence analysis., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. automate, large, scale, cDNA, sequence, analysis, BLAST, database, gene is listed by: NIAID THIS RESOURCE IS NO LONGER IN SERVICE SCR_016612 Desktop cDNA Annotation System 2026-08-29 11:25:50 0
ALGGEN-PROMO
 
Resource Report
Resource Website
100+ mentions
ALGGEN-PROMO (RRID:SCR_016926) data analysis software, data or information resource, data processing software, laboratory portal, organization portal, portal, sequence analysis software, service resource, software application, software resource Web tool to identify putative transcription factor binding sites (TFBS) in DNA sequences from a species or groups of species of interest. Used for detection of known transcription regulatory elements using species-tailored searches. identify, transcription, factor, binding, site, DNA, sequence, species, regulatory, element, search PMID:11847087
PMID:12824386
Free, Available for download, Freely available SCR_016926 PROMO, ALGorithmics and GENetics PROMO, ALGGEN, ALGGEN-PROMO 2026-08-29 11:25:53 434
smMIPfil
 
Resource Report
Resource Website
1+ mentions
smMIPfil (RRID:SCR_016892) data analysis software, data processing software, software application, software resource Software tool for single molecule Molecular Inversion Probes data analysis. This is a stand-alone perl script. Except that this is dependent on the samtools, no installation required. nucleotide, DNA, read, unique, molecular, identifier, single, inversion, probe, data, analysis, mutation, sequence requires: SAMTOOLS Free, Available for download, Freely available SCR_016892 single molecule Molecular Inversion Probesfil, smMIPfil 2026-08-29 11:25:25 2
CRISPR-P
 
Resource Report
Resource Website
10+ mentions
CRISPR-P (RRID:SCR_016941) analysis service resource, data access protocol, production service resource, service resource, software resource, web service Web tool for synthetic single-guide RNA design of CRISPR-system in plants. Allows to search for high specificity Cas9 target sites within DNA sequences of interest, which also provides off-target loci prediction for specificity analyses and marks restriction enzyme cutting site to every sgRNA for further convenient in experiment. synthetic, single, RNA, CRISP, plant, Cas9, target, DNA, sequence, analysis, restriction, enzyme, sgRNA, bio.tools is listed by: Debian
is listed by: bio.tools
Fundamental Research Funds for the Central Universities ;
National Basic Research Program of China ;
Program for New Century Excellent Talents in University
PMID:24719468 Free, Freely available biotools:CRISPR-P https://bio.tools/CRISPR-P SCR_016941 CRISPR-P 2.0, Clustered Regularly Interspaced Short Palindromic Repeats P, CRISPR P 2026-08-29 11:25:53 42
BioNano: Irys system
 
Resource Report
Resource Website
10+ mentions
BioNano: Irys system (RRID:SCR_016754) instrument resource System by BioNano Genomics ( formerly BioNanomatrix) which provides optical next generation mapping (NGM). Used for sequence assembly and structural variation analysis. Provides Scaffold Bionano genome mapping data with sequencing data to improve assembly contiguity, reduce sequencing coverage needed, and automatically correct errors in sequencing based assemblies. instrument, Irys, system, BioNano Genomics, BioNanomatrix, optical, next, generation, mapping, sequence, assembly, structural, variation, analysis, data, Commercially available https://raw.githubusercontent.com/SciCrunch/RRID-Instruments/refs/heads/main/PDF/SCR_016754.pdf https://bionanogenomics.com/wp-content/uploads/2017/01/2016-Irys-System-Brochure.pdf https://bionanogenomics.com/technology/genome-assembly/ SCR_016754 2026-08-29 11:25:22 35
PICRUSt
 
Resource Report
Resource Website
10+ mentions
PICRUSt (RRID:SCR_016855) PICRUSt simulation software, software application, software resource Software package to predict metagenome functional content from marker gene (e.g., 16S rRNA) surveys and full genomes. Used to predict which gene families are present and then combines gene families to estimate the composite metagenome. predict, metagenome, functional, content, DNA, sample, marker, gene, sequence, data, microbiome, 16S, RNA is related to: PICRUSt2 ARO W911NF1110473;
Canada Research Chairs program ;
Canadian Institutes of Health Research ;
Crohn’s and Colitis Foundation of America ;
Howard Hughes Medical Institute ;
NHGRI R01 HG004872;
NHGRI R01 HG005969;
NHGRI U01 HG004866;
NIDDK P01 DK078669;
NSF CAREER DBI1053486;
Sloan Foundation
PMID:23975157 Free, Available for download, Freely available SCR_016856 SCR_016855 Phylogenetic Investigation of Communities by Reconstruction of Unobserved States, PICRUSt 2026-08-29 11:25:24 45
KAT
 
Resource Report
Resource Website
10+ mentions
KAT (RRID:SCR_016741) KAT data analysis software, data processing software, software application, software resource, software toolkit Software that generates, analyses and compares k-mer spectra produced from sequence files. Used to quality control NGS datasets and genome assemblies. generate, analyse, compare, k-mer, spectra, sequence, file, quality, control, NGS, dataset, genome, assembly, bio.tools is listed by: Debian
is listed by: bio.tools
BBSRC DOI:10.1093/bioinformatics/btw663 Free, Available for download, Freely available biotools:kat http://www.earlham.ac.uk/kat-tools, https://bio.tools/kat SCR_016741 K-mer Analysis Toolkit 2026-08-29 11:25:52 21
CCTOP
 
Resource Report
Resource Website
10+ mentions
CCTOP (RRID:SCR_016963) CCTOP analysis service resource, data access protocol, production service resource, service resource, software resource, web service Web application providing transmembrane topology prediction. Server incorporates topology information from existing experimental and computational sources using the probabilistic framework of hidden Markov model. Provides the option to precede the topology prediction with signal peptide prediction and transmembrane globular protein discrimination. Given the amino acid sequence of a putative α helical transmembrane protein, CCTOP predicts its topology i.e. localization of membrane spanning regions and orientation of segments between them. transmembrane, topology, prediction, signal, peptide, globular, protein, discrimination, amino, acid, sequence, region, orientation, segment, bio.tools is listed by: Debian
is listed by: bio.tools
works with: PDBTM
works with: Topology Data Bank of Transmembrane Proteins
works with: TopDom
Hungarian Scientific Research Fund PMID:25943549 Free, Freely available biotools:cctop https://bio.tools/cctop SCR_016963 CCTOP, Consensus Constrained TOPology 2026-08-29 11:25:54 31
RNAmmer
 
Resource Report
Resource Website
100+ mentions
RNAmmer (RRID:SCR_017075) analysis service resource, data access protocol, data analysis service, data analysis software, data processing software, production service resource, service resource, software application, software resource, standalone software, web service Software package to predict ribosomal RNA genes in full genome sequences by utilising two levels of Hidden Markov Models. Consistent and rapid annotation of ribosomal RNA genes. predict, ribosomal, RNA, gene, full, genome, sequence, HMM, rRNA has parent organization: Technical University of Denmark; Lyngby; Denmark Danish Center for Scientific Computing ;
EMBIO at the University of Oslo ;
European Union ;
Research Council of Norway
PMID:17452365 Restricted SCR_017075 2026-08-29 11:25:55 120
Bestus Bioinformaticus Duk
 
Resource Report
Resource Website
100+ mentions
Bestus Bioinformaticus Duk (RRID:SCR_016969) BBDuk data analysis software, data analytics software, data processing software, software application, software resource Software tool for trimming and filtering sequencing data. Used to combine data quality related trimming, filtering, and masking operations into a single tool adapter. BBDuk2 allows multiple kmer based operations in a single pass. sequencing, data, quality, trimming, filtering, masking, operation, single, tool, adapter, contaminant, sequence, GC, length, entropy, format, conversion, histogram, kmer, estimation, decontamination is listed by: Bestus Bioinformaticus Tools
has parent organization: DOE Joint Genome Institute
works with: Reformat
http://seqanswers.com/forums/showthread.php?t=42776, https://www.geneious.com/plugins/bbduk/#links SCR_016969 BB Duk, Decontamination Using Kmers, Bestus Bioinformaticus Decontamination using kmers, BBDuk2, BBDUK, BBDuk, BBDuk 2, Bestus Bioinformaticus Decontamination Using kmers 2026-08-29 11:25:27 212
MITE-Tracker
 
Resource Report
Resource Website
1+ mentions
MITE-Tracker (RRID:SCR_017030) MITE Tracker data analysis software, data processing software, sequence analysis software, software application, software resource Open source software tool for identifying miniature inverted repeat transposable elements in large genomes. Used to process large scale genomes, to find and classify MITEs using an efficient alignment strategy to retrieve nearby inverted repeat sequences. genomic, sequence, discover, miniature, inverted, repeat, transposable, element, clustering, cdhit uses: NCBI BLAST
is listed by: OMICtools
is related to: Python Programming Language
National Council for Science and Technology ;
Argentina ;
National Institute of Agricultural Technology
DOI:10.1186/s12859-018-2376-y Free, Available for download, Freely available OMICS_32242 SCR_017030 MITE Tracker, Miniature Inverted repeats Transposable Elements Tracker 2026-08-29 11:25:24 4
Phymm and PhymmBL
 
Resource Report
Resource Website
10+ mentions
Phymm and PhymmBL (RRID:SCR_004751) Phymm, PhymmBL software resource Software for Phylogenetic Classification of Metagenomic Data with Interpolated Markov Models to taxonomically classify DNA sequences and accurately classify reads as short as 100 bp. PhymmBL, the hybrid classifier included in this distribution which combines analysis from both Phymm and BLAST, produces even higher accuracy. metagenome, sequence, taxonomy, classification, phylogenetic classification, genome, short read is listed by: OMICtools
has parent organization: University of Maryland; Maryland; USA
NLM R01-LM006845 PMID:19648916
PMID:21527926
Open-source license OMICS_01461 SCR_004751 2026-08-29 11:22:11 12
GeneDB Tbrucei
 
Resource Report
Resource Website
10+ mentions
GeneDB Tbrucei (RRID:SCR_004786) GeneDB_Tbrucei, GeneDB Tbrucei, GeneDB T. brucei analysis service resource, data analysis service, data or information resource, database, production service resource, service resource Database of the most recent sequence updates and annotations for the T. brucei genome. New annotations are constantly being added to keep up with published manuscripts and feedback from the Trypanosomatid research community. You may search by Protein Length, Molecular Mass, Gene Type, Date, Location, Protein Targeting, Transmembrane Helices, Product, GO, EC, Pfam ID, Curation and Comments, and Dbxrefs. BLAST and other tools are available. T. brucei possesses a two-unit genome, a nuclear genome and a mitochondrial (kinetoplast) genome with a total estimated size of 35Mb/haploid genome. The nuclear genome is split into three classes of chromosomes according to their size on pulsed-field gel electrophoresis, 11 pairs of megabase chromosomes (0.9-5.7 Mb), intermediate (300-900 kb) and minichromosomes (50-100 kb). The T. brucei genome contains a ~0.5Mb segmental duplication affecting chromosomes 4 and 8, which is responsible for some 75 gene duplicates unique to this species. A comparative chromosome map of the duplicons can be accessed here (PubmedID 18036214). Protozoan parasites within the species Trypanosoma brucei are the etiological agent of human sleeping sickness and Nagana in animals. Infections are limited to patches of sub-Saharan Africa where insects vectors of the Glossina genus are endemic. The most recent estimates indicate between 50,000 - 70,000 human cases currently exist, with 17 000 new cases each year (WHO Factsheet, 2006). In collaboration with GeneDB, the EuPathDB genomic sequence data and annotations are regularly deposited on TriTrypDB where they can be integrated with other datasets and queried using customized queries. blast, sequence, annotation, genome is used by: NIF Data Federation
is related to: AmiGO
is related to: TriTrypDB
has parent organization: GeneDB
Wellcome Trust PMID:16020726 nlx_78417 SCR_004786 Trypanosoma brucei TREU927 homepage on GeneDB, Trypanosoma brucei TREU927 on GeneDB 2026-08-29 11:22:13 17

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