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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Specification URL Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
HyPhy
 
Resource Report
Resource Website
1000+ mentions
HyPhy (RRID:SCR_016162) data analysis software, data processing software, sequence analysis software, software application, software resource, software toolkit Open source software package for comparative sequence analysis using stochastic evolutionary models. Used for analysis of genetic sequence data in particular the inference of natural selection using techniques in phylogenetics, molecular evolution, and machine learning. analysis, genetic, sequence, multiply, alignment, rate, pattern, data, evolution, platform, python, r, bio.tools is listed by: Debian
is listed by: bio.tools
is listed by: OMICtools
NIGMS R01 ;
NIH R01 AI47745;
NIH U01 AI43638;
NSF DBI-0096033;
NSF DEB-9996118;
University of California Universitywide AIDS Research Program IS02-SD-701;
University of California ;
San Diego Center for AIDS Research/NIAID Developmental Award 2 P30 AI36214
PMID:15509596 Free, Available for download, Freely available SCR_016271, biotools:HyPhy, OMICS_04235 https://sources.debian.org/src/hyphy-pt/, https://veg.github.io/hyphy-site/, https://github.com/veg/hyphy, https://bio.tools/HyPhy, SCR_016162 HyPhy:Hypothesis Testing using Phylogenies, Hyphy-pt 2026-09-03 04:53:36 1586
zUMIs
 
Resource Report
Resource Website
100+ mentions
zUMIs (RRID:SCR_016139) data analysis software, data processing software, software application, software resource Software pipeline to process RNA-seq data with UMIs. The input to this pipeline is paired-end fastq files, where one read contains the cDNA sequence and the other read contains UMI and Cell Barcode information. single-cell, RNA-seq, UMI, Genomics, shell, r, perl, rna, cdna, cell, sequencing, bio.tools is listed by: bio.tools
is listed by: Debian
DOI:10.1101/153940 Open source, Free, Available for download biotools:zumis https://bio.tools/zumis SCR_016139 zumi 2026-09-03 04:53:28 128
Fastml
 
Resource Report
Resource Website
100+ mentions
Fastml (RRID:SCR_016092) data access protocol, software resource, web application, web service Web application for the reconstruction of ancestral sequences. It computes maximum likelihood ancestral sequence reconstruction based on the phylogenetic relations between homologous sequences. ancestral, amino-acid, sequence, reconstruction, phylogenetic, relation, accurate, bio.tools is listed by: Debian
is listed by: bio.tools
is listed by: OMICtools
Bioinformatics Center at Tel-Aviv University ;
Israel Science Foundation 878/09
PMID:22661579 Free, Freely available biotools:fastml, OMICS_08650 https://bio.tools/fastml, https://sources.debian.org/src/fastml/ SCR_016092 The FastML Server 2026-09-03 04:53:33 111
BioPlex
 
Resource Report
Resource Website
1000+ mentions
BioPlex (RRID:SCR_016144) data or information resource, data repository, database, service resource, storage service resource Database of cell lines with each expressing a tagged version of a protein from the ORFeome collection. The overarching project goal is to determine protein interactions for every member of the collection. cell, line, protein, immunopurification, mass, spectrometry, interaction, bio.tools, FASEB list is listed by: bio.tools
is listed by: Debian
has parent organization: Harvard Medical School; Massachusetts; USA
Canadian Institutes for Health Research ;
NHGRI U41HG006673;
NIDDK K01 DK098285
PMID:28514442 biotools:bioplex_2.0 https://bio.tools/bioplex_2.0 SCR_016144 BioPlex (biophysical interactions of ORFeome-based complexes), Harvard BioPlex, Biophysical Interactions of Orfeome-based comPLEXes (BioPLEX) 2026-09-03 04:53:35 1378
mentha
 
Resource Report
Resource Website
100+ mentions
mentha (RRID:SCR_016148) data analysis software, data or information resource, data processing software, database, software application, software resource, web application Software that archives evidence collected from different sources, then analyzes and presents these data. Its data come from manually curated protein-protein interaction databases that have adhered to the IMEx consortium. protein, ppi, imex, interactome, archival, bio.tools, FASEB list uses: PSICQUIC Registry
is listed by: Debian
is listed by: bio.tools
is related to: IMEx - The International Molecular Exchange Consortium
PMID:23900247 biotools:mentha, r3d100011124 https://bio.tools/mentha, https://doi.org/10.17616/R3SP8V SCR_016148 2026-09-03 04:53:48 156
Exonerate
 
Resource Report
Resource Website
100+ mentions
Exonerate (RRID:SCR_016088) alignment software, data processing software, image analysis software, software application, software resource, software toolkit Software package for sequence alignment of pairwise sequence comparison. Exonerate can be used to align sequences using many alignment models, exhaustive dynamic programming, or a variety of heuristics., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. sequence, alignment, pairwise, comparison, dynamic, programming, heuristic, bio.tools is used by: ExonerateTransferAnnotation
is listed by: Debian
is listed by: bio.tools
has parent organization: Wellcome Trust Sanger Institute; Hinxton; United Kingdom
PMID:15713233 THIS RESOURCE IS NO LONGER IN SERVICE biotools:exonerate https://bio.tools/exonerate SCR_016088 2026-09-03 04:53:46 376
Necklace
 
Resource Report
Resource Website
1+ mentions
Necklace (RRID:SCR_016103) alignment software, data processing software, image analysis software, software application, software resource Software that combines reference and assembled transcriptomes for RNA-Seq analysis. It replaces many manual steps in the pipeline of RNA-Seq analyses involving species with incomplete genome or annotations. RNA, Transcriptome, Non-model species, bio.tools is listed by: bio.tools
is listed by: Debian
PMID:28836999 Free, Available for download biotools:necklace https://bio.tools/necklace SCR_016103 Lace software 2026-09-03 04:53:33 3
BLINK
 
Resource Report
Resource Website
1+ mentions
BLINK (RRID:SCR_016288) algorithm resource, data analysis software, data processing software, software application, software resource Software for next level of genome wide association studies with both individuals and markers in millions. The method releases the requirement that causative genes are evenly distributed on genome and consequently boosts statistical power. GWAS, SNP, dataset, r, genome, bayesian, linkage, nested, keyway, statistic, bio.tools is listed by: Debian
is listed by: bio.tools
Free, Available for download, Tutorial available biotools:BLINK https://bio.tools/BLINK SCR_016288 BLINK (Bayesian-information and Linkage-disequilibrium Iteratively Nested Keyway) 2026-09-03 04:53:42 2
MetaCyto
 
Resource Report
Resource Website
1+ mentions
MetaCyto (RRID:SCR_016415) data analysis software, data processing software, software application, software resource, software toolkit Software tool for automated meta-analysis of mass and flow cytometry data. Provides functions for preprocessing, automated gating and meta-analysis of cytometry data and collection of cytometry data from the ImmPort database. automated, analysis, meta, flow, cytometry, data, bio.tools is listed by: Bioconductor
is listed by: NIDDK Information Network (dkNET)
is listed by: bio.tools
is listed by: Debian
is related to: The Immunology Database and Analysis Portal (ImmPort)
the National Institute of Allergy and Infectious Diseases HHSN272201200028C Free, Available for download, Freely available biotools:metacyto https://bio.tools/metacyto SCR_016415 2026-09-03 04:53:47 5
SMAGEXP
 
Resource Report
Resource Website
1+ mentions
SMAGEXP (RRID:SCR_016360) SMAGEXP data analysis software, data processing software, software application, software resource, software toolkit Software toolkit for transcriptomics data meta-analysis. It integrates metaMA and metaRNAseq packages into Galaxy, carries out meta-analysis of gene expression data, handles microarray data from Gene Expression Omnibus (GEO) database, and more. transcriptomics, data, meta, analysis, MicroArrays, RNA-Seq, Galaxy, gene, expression, next, generation, sequencing, bio.tools is listed by: Debian
is listed by: bio.tools
is related to: Galaxy
is related to: Gene Expression Omnibus
is related to: metaMA
is related to: metaRNASeq
PMID:30698691 Free, Available for download, Freely available biotools:SMAGEXP https://bio.tools/SMAGEXP SCR_016360 Statistical Meta Analysis for Gene EXPression 2026-09-03 04:53:45 2
FluxModeCalculator
 
Resource Report
Resource Website
1+ mentions
FluxModeCalculator (RRID:SCR_016290) data analysis software, data processing software, software application, software resource Software for performing flux mode analysis in stoichiometric models. FluxModeCalculator enables large-scale elementary flux mode (EFM) computation and uses the OpenMP API to optimally exploit processor architectures with multiple cores., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. efm, flux, stoichiometry, algorithm, matlab, linux, model, magnitude, bio.tools is listed by: Debian
is listed by: bio.tools
Biobanking and Biomolecular Resources Research Infrastructure (BBMRI) ;
CardioVascular Research Netherlands (CVON-ENERGISE) ;
Center of Medical Systems Biology (CMSB) ;
European Network for Genetic and Genomic Epidemiology (ENGAGE) ;
Netherlands Consortium for Systems Biology (NCSB)
PMID:26685305 THIS RESOURCE IS NO LONGER IN SERVICE biotools:fluxmodecalculator, OMICS_10894 https://bio.tools/fluxmodecalculator SCR_016290 Flux Mode Calculator 2026-09-03 04:53:53 1
Lifebit Deploit
 
Resource Report
Resource Website
1+ mentions
Lifebit Deploit (RRID:SCR_016428) analysis service resource, data analysis service, data management software, production service resource, service resource, software application, software resource Platform for computing management for data analysis on the cloud from the Lifebit company. Allows the computational analyses to be permanently linked to live analyses pipelines. Lifebit, compute, management, data, analysis, cloud, integrate, data, reproduce, transparent, bio.tools is listed by: Debian
is listed by: bio.tools
PMID:28398311 Commercially available biotools:nextflow https://bio.tools/nextflow SCR_016428 2026-09-03 04:53:40 2
Microscopy Image Browser
 
Resource Report
Resource Website
100+ mentions
Microscopy Image Browser (RRID:SCR_016560) MIB data analysis software, data processing software, data visualization software, image processing software, software application, software resource, standalone software Software package for advanced image processing, analysis, segmentation and visualization of multi-dimensional (2D-4D) light and electron microscopy datasets. segmentation, analysis, multidimentional, dataset, light, electron, microscopy, image, processing, visualization, data, bio.tools is listed by: Debian
is listed by: bio.tools
is related to: MATLAB
Biocenter Finland ;
Biological Imaging Network Academy of Finland ;
University of Helsinki
PMID:26727152 Free, Available for download, Freely available biotools:mib https://www.youtube.com/watch?v=I9FWmJX_nl0&index=1&list=PLGkFvW985wz8cj8CWmXOFkXpvoX_HwXzj, https://bio.tools/mib SCR_016560 MIB, Microscopy Image Browser 2026-09-03 04:53:43 160
DINIES
 
Resource Report
Resource Website
1+ mentions
DINIES (RRID:SCR_016505) DINIES data analysis software, data processing software, sequence analysis software, software application, software resource, web application Web server for predicting unknown drug-target interaction networks from various types of biological data in the framework of supervised network inference. predict, drug, target, interaction, network, biological, data, chemical, structure, protein, amino acid, sequence, domain, bio.tools is listed by: GenomeNet
is listed by: Debian
is listed by: bio.tools
is related to: KEGG
has parent organization: Kyoto University; Kyoto; Japan
Ministry of Education ;
Culture ;
Sports ;
Science and Technology of Japan ;
the Japan Science and Technology Agency ;
the Japan Society for the Promotion of Science
PMID:24838565 Free, Freely available biotools:dinies https://bio.tools/dinies SCR_016505 Drug target Interaction Network Inference Engine based on Supervised analysis 2026-09-03 04:53:44 6
MentaLiST
 
Resource Report
Resource Website
10+ mentions
MentaLiST (RRID:SCR_016469) data analysis software, data processing software, sequence analysis software, software application, software resource Software for a MLST (multi-locus sequence typing) caller, based on a k-mer counting algorithm and written in the Julia language. Designed and implemented to handle large typing schemes. next, generation, sequencing, multi, locus, sequence, typing, pathogen, surveillance, gene, identify, strain, type, housekeeping, whole, genome, sequencing, data, bacteria, genotyping, bio.tools is listed by: bio.tools
is listed by: Debian
Canadian Institute for Health Research ;
Genome BC ;
Genome Canada
PMID:29319471 Free, Available for download, Freely available biotools:mentalist https://bio.tools/mentalist SCR_016469 2026-09-03 04:53:51 15
cisTEM
 
Resource Report
Resource Website
50+ mentions
cisTEM (RRID:SCR_016502) cisTEM data processing software, image processing software, software application, software resource Software to process cryo-EM images of macromolecular complexes and obtain high-resolution 3D reconstructions from them. data, processing, high, resolution, electron, cryo, macroscopy, single, particle, averaging, image, macromolecule, high, resolution, 3D, bio.tools is listed by: bio.tools
is listed by: Debian
Howard Hughes Medical Institute DOI:10.7554/eLife.35383 Open source, Trial available biotools:cistem https://bio.tools/cistem SCR_016502 computational imaging system for Transmission Electron Microscopy 2026-09-03 04:54:03 67
Pavian
 
Resource Report
Resource Website
10+ mentions
Pavian (RRID:SCR_016679) analysis service resource, data analysis service, production service resource, service resource, software resource, web application Software R package for interactive analysis of metagenomics classification results with a special focus on infectious disease diagnosis. Used for analyzing and visualization of metagenomics classification results from classifiers such as Kraken, Centrifuge and MetaPhlAn. Provides an alignment viewer for validation of matches to a particular genome. interactive, analysis, metagenomics, classification, result, infectious, disease, diagnosis, data, visualization, bio.tools is listed by: Debian
is listed by: bio.tools
is related to: Centrifuge Classifier
NHGRI R01 HG006677;
NIGMS R01 GM083873;
U. S. Army Research Office W911NF1410490
DOI:10.1101/084715 Free, Freely available biotools:pavian https://fbreitwieser.shinyapps.io/pavian/, https://bio.tools/pavian SCR_016679 2026-09-03 04:53:58 33
Centrifuge Classifier
 
Resource Report
Resource Website
10+ mentions
Centrifuge Classifier (RRID:SCR_016665) data analysis software, data processing software, sequence analysis software, software application, software resource Software for rapid and sensitive classification of metagenomic sequences. Used for the classification of DNA sequences from microbial samples and analysis of large metagenomics data sets on conventional desktop computers. classification, large, metagenomic, sequence, DNA, microbial, sample, analysis, data, desktop, computer, bio.tools is listed by: bio.tools
is listed by: Debian
is listed by: OMICtools
is related to: Pavian
has parent organization: Center for Computational Biology at JHU
NHGRI R01 HG006677;
NIGMS R01 GM083873;
NSF ABI1356078;
U. S. Army Research Office W911NF1410490
DOI:10.1101/gr.210641.116 Free, Available for download, Freely available biotools:centrifuge, OMICS_12217 https://github.com/infphilo/centrifuge, https://bio.tools/centrifuge, https://sources.debian.org/src/centrifuge/ SCR_016665 2026-09-03 04:53:51 10
TB PORTALS
 
Resource Report
Resource Website
10+ mentions
TB PORTALS (RRID:SCR_016594) consortium, data or information resource, data repository, disease-related portal, organization portal, portal, service resource, storage service resource, topical portal Web based open access platform for global drug resistant tuberculosis data sharing and analysis. The NIAID TB Portals program and consortium of clinicians and scientists from countries with a heavy burden of TB, especially drug resistant TB, to collect TB data. collect, data, sharing, analysis, tuberculosis, global, bio.tools is listed by: NIAID
is listed by: bio.tools
is listed by: Debian
tuberculosis NIH DOI:10.1128/JCM.01013-17 Free, Freely available r3d100013925, biotools:TB_Portals https://bio.tools/TB_Portals, https://doi.org/10.17616/R31NJN8L SCR_016594 2026-09-03 04:54:07 20
NMRProcFlow
 
Resource Report
Resource Website
10+ mentions
NMRProcFlow (RRID:SCR_016592) data processing software, data visualization software, software application, software resource Software as graphical and interactive tool dedicated to 1D spectra processing for NMR-based metabolomics. NMR, metabolomics, data, viewer, spectra, processing, graphical, interface, bio.tools uses: R Project for Statistical Computing
is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
French National Infrastructure in Metabolomics and Fluxomics DOI:10.1007/s11306-017-1178-y Free, Available for download, Freely available biotools:nmrprocflow, SCR_022777 https://github.com/INRA/NMRProcFlow, https://bio.tools/nmrprocflow, https://github.com/inra/nmrprocflow SCR_016592 Nuclear Magnetic Resonance PROcessing FLOW, Nuclear Magnetic Resonance Processing Flow 2026-09-03 04:53:45 29

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