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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Specification URL Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
Center for Disease Control and Prevention: Genetic Testing Reference Materials Coordination Program
 
Resource Report
Resource Website
1+ mentions
Center for Disease Control and Prevention: Genetic Testing Reference Materials Coordination Program (RRID:SCR_013029) data or information resource, portal, topical portal The goal of the Genetic Testing Reference Materials Coordination Program (GeT-RM) is to coordinate a self-sustaining community process to improve the availability of appropriate and characterized reference materials for: Quality control (QC), Proficiency testing (PT), Test development & validation, Research. The purpose of this program is: - To help the genetic testing community obtain appropriate and characterized reference materials - To facilitate and coordinate information exchange between users and providers of QC and reference materials - To coordinate efforts for contribution, development, characterization and distribution of reference materials for genetic testing Get-RM provides information about cell lines, DNA, and other kinds of materials that could be used as reference materials for molecular genetic testing. Some of these materials have been characterized by the GeT-RM program and can be divided into three categories: - Genetic Inherited Disease & Pharmacogenetics This section includes information about cell lines, DNA, and other samples that can be used as reference materials for various inherited diseases (including cystic fibrosis, fragile X, Huntington disease, and Ashkenazi Jewish-related diseases), pharmacogenetic loci, and biochemical genetics. The GeT-RM program has confirmed the genotype of many of the genomic DNA samples through testing in multiple clinical genetic laboratories. - Molecular Oncology This section includes information about commercially available cell lines, DNA, and other kinds of materials that could be used as reference materials for various types of cancers, including leukemia/lymphoma and solid tumors. - Infectious Disease This section includes information about commercially available cell lines, DNA, and other kinds of materials that could be used as reference materials for various infectious disease pathogens including viruses, bacteria, and protozoa. fragile x, genetic, genetics, genetic testing, ashkenazi, bacteria, biochemical, cancer, cell, cell line, coordination, cystic fibrosis, development, disease, dna, genomic, genotype, huntington disease, inherited, jewish, leukemia, locus, lymphoma, material, molecular, oncology, pathogen, pharmacogentic, protozoa, quality, solid, testing, tumor, virus has parent organization: Centers for Disease Control and Prevention nif-0000-10189 SCR_013029 CDC GeT-RM Program 2026-09-12 12:57:57 3
Human Genome Project Information
 
Resource Report
Resource Website
50+ mentions
Human Genome Project Information (RRID:SCR_013028) data or information resource, funding resource, narrative resource, portal, slide, topical portal, training material, video resource This resource gives information about the U.S. Human Genome Project, which was was a 13-year effort to to discover all the estimated 20,000-25,000 human genes and make them accessible for further biological study. The primary project goals were to: - identify all the approximately 20,000-25,000 genes in human DNA, - determine the sequences of the 3 billion chemical base pairs that make up human DNA, - store this information in databases, - improve tools for data analysis, - transfer related technologies to the private sector, and - address the ethical, legal, and social issues (ELSI) that may arise from the project. To help achieve these goals, researchers also studied the genetic makeup of several nonhuman organisms. These include the common human gut bacterium Escherichia coli, the fruit fly, and the laboratory mouse. These parallel studies helped to develop technology and interpret human gene function. Sponsors: The DOE Human Genome Program and the NIH National Human Genome Research Institute (NHGRI) together sponsored the U.S. Human Genome Project. escherichia coli, fruit fly, function, gene, genome, genetic, bacterium, base pair, biological, dna, human, mouse, sequence, FASEB list has parent organization: National Institutes of Health
has parent organization: United States Department of Energy
nif-0000-10252 SCR_013028 HGP 2026-09-12 12:57:57 59
Genetic Analysis Software
 
Resource Report
Resource Website
1+ mentions
Genetic Analysis Software (RRID:SCR_013155) GAS catalog, data or information resource, data set, database, software resource THIS RESOURCE IS NO LONGER IN SERVICE. Documented on May 4th,2023. Listing of computer software for the gene mapping community on the following topics: genetic linkage analysis for human pedigree data, QTL analysis for animal/plant breeding data, genetic marker ordering, genetic association analysis, haplotype construction, pedigree drawing, and population genetics. The inclusion of a program should not be interpreted as an endorsement to that program from us. In the last few years, new technology produces new types of genetic data, and the scope of genetic analyses change dramatically. It is no longer obvious whether a program should be included or excluded from this list. Topics such as next-generation-sequencing (NGS), gene expression, genomics annotation, etc. can all be relevant to a genetic study, yet be specialized topics by themselves. Though programs on variance calling from NSG can be in, those can sequence alignment might be out; programs on eQTL can be in, those on differential expression might be out. This page was created by Dr. Wentian Li, when he was at Columbia University (1995-1996). It was later moved to Rockefeller University (1996-2002), and now takes its new home at North Shore LIJ Research Institute (2002-now). The present copy is maintained by Jurg Ott as a single file. More than 240 programs have been listed by December 2004, more than 350 programs by August 2005, close to 400 programs by December 2006, and close to 480 programs by November 2008, and over 600 programs by October 2012. A version of the searchable database was developed by Zhiliang Hu of Iowa State University, and a recent round of updating was assisted by Wei JIANG of Harbin Medical School. Some earlier software can be downloaded from EBI: ftp://ftp.ebi.ac.uk/pub/software/linkage_and_mapping/ (Linkage and Mapping Software Repository), and http://genamics.com/software/index.htm may contain archived copy of some programs. gene mapping, gene, genetic, genomic, model, modeling, software program, genetic linkage analysis, qtl analysis, genetic marker order, genetic association analysis, haplotype construction, pedigree drawing, population genetics is used by: NIF Data Federation
lists: EM-DECODER
lists: ENTROPY BLOCKER
lists: SOAP
lists: ADEGENET
lists: 2LD
lists: SQTL
lists: POLYMORPHISM
lists: EDAC
lists: FEST
lists: GENEHUNTER SAD
lists: COMDS
lists: CHAPLIN
lists: CRIMAP
lists: DCHIP LINKAGE
lists: FLOSS
lists: HAP 1
lists: HAPSCOPE
lists: LDB/LDB+
lists: LOCUSMAP
lists: MRH
lists: PEDIGREE-VISUALIZER
lists: PEDPHASE
lists: QTL CAFE
lists: RHMAPPER
lists: R/GC, R/GCF
lists: R/GWAPOWER
lists: R/WEIGHTED FDR
lists: SIMM
lists: SOLAR
lists: TDTHAP
lists: HWESTRATA
lists: TDT-PC
lists: EQTL EXPLORER
lists: GAS2
lists: LDMET
lists: LAMBDAA
lists: EIGENSOFT/EIGENSTRAT
lists: Happy
lists: LAMP
lists: CLUSTAG
lists: OSA
lists: SIMIBD
lists: SNPSTATS
lists: Haploview
lists: QGene
lists: PAWE-3D
lists: MILD
lists: PEDPLOT
lists: GS-EM
lists: PEDSCRIPT
lists: Multipoint Identical-by-descent Method
lists: PARENTE
lists: Integrated Software
lists: PEDRAW/WPEDRAW
lists: POPDIST
lists: TDTASP
lists: TDTPOWER
lists: TDT/S-TDT
lists: HAPLOBLOCKFINDER
lists: HAPMIXMAP
lists: Genotype-IBD Sharing Test
lists: LDGROUP
lists: LDHAT
lists: LDMAP
lists: LDHEATMAP
lists: LDSELECT
lists: LINKAGE
lists: LDSUPPORT
lists: FASTLINK
lists: LINKAGE - CEPH
lists: LSP
lists: Whap
lists: TREESCAN
lists: Graphical Overview of Linkage Disequilibrium
lists: MAIA
lists: MULTIMAP
lists: R/ADEGENET
lists: R/ENTROPY BLOCKER
lists: BEAM
lists: BMAPBUILDER
lists: POPGEN
lists: RTDT
lists: R/SPECTRAL-GEM
lists: R/STEPWISE
lists: HAPLOCLUSTERS
lists: TKMAP
lists: CLUMP
lists: FAMOZ
lists: INTEGRAYEDMAP
lists: SIBMED
lists: POOLSCORE
lists: LDA
lists: LAPSTRUCT
lists: BETA
lists: ALTree
lists: TRANSMIT
lists: ETDT
lists: R/TDTHAP
lists: RVTESTS
lists: S
lists: ET-TDT
lists: ILR
lists: MAPCREATOR
lists: MAPMAKER/SIBS
lists: MAP MANAGER QT
lists: MGA-MAPF2
lists: Pedigree-Draw
lists: FASTMAP (1)
lists: ASPEX
lists: PEDJAVA
lists: PEDPEEL
lists: SIMCOAL
lists: SNPHAP
lists: SNPHARVESTER
lists: SNP-HWE
lists: TAGSNP
lists: FASTMAP (2)
lists: FASTSLINK
lists: GASP
lists: GENOGRAM-MAKER
lists: GENEHUNTER++SAD
lists: GENEPI.JAR
lists: BDGEN
lists: TLINKAGE
lists: GENOME
lists: EASYPOP
lists: GENOMESIMLA
lists: TRAP
lists: CARTHAGENE
lists: ACT
lists: ADMIXMAP
lists: 2DMAP
lists: ALBERT
lists: 2SNP
lists: AGEINF
lists: ALLASS
lists: PEDIGREEQUERY
lists: PATH
lists: MULTIQTL
lists: SPERMSEG
lists: FASTER
lists: Platypus
lists: KIN
lists: SNP ASSISTANT
lists: GRONLOD
lists: COMBIN
lists: ARLEQUIN
lists: SEGPATH
lists: JENTI
lists: SCOUT
lists: HAPLOREC
lists: UNPHASED
lists: POWER
lists: HAPLO 1
lists: HAPLO 2
lists: CHIP2SPELL
lists: MAP MANAGER QTX
lists: G-MENDEL
lists: ASSOCIATIONVIEWER
lists: WHICHRUN
lists: GENECLASS
lists: MAREYMAP
lists: HELIXTREE
lists: SVCC
lists: GENEHUNTER-MODSCORE
lists: FAMHAP
lists: BAMA
lists: WEBQTL
lists: HAPLOVISUAL
lists: CASPAR
lists: GC/GCF
lists: MIXSCORE
lists: POWQ
lists: QTLNetwork
lists: SIMULAPLOT
lists: SQTDT/SPDT
lists: FESTA
lists: BOTTLENECK
lists: PAP
lists: QUANTO
lists: R/QTL
lists: SNPEM
lists: GENEPOOL
lists: EPISTACY
lists: VITESSE
lists: LEA
lists: DMAP
lists: MOSCPHASER
lists: UMAKE
lists: TDT-AE
lists: HAPLOWSER
lists: STEPC
lists: RECORD
lists: QUTIE
lists: R/COMPOSITELD
lists: FINESSE
lists: R/EHP
lists: R/HCLUST
lists: STEPWISE
lists: genehunter-imprinting
lists: PBAT
lists: R/BARS
lists: HARDY
lists: R/ARP.GEE
lists: R/COVIBD
lists: STRAT
lists: TREELD
lists: TUNA
lists: SIBSIM
lists: IGG
lists: ALLELIX
lists: ALLEGRO
lists: ALOHOMORA
lists: ALP
lists: AMELIA
lists: ANALYZE
lists: ANCESTRY
lists: APE
lists: BARS
lists: APL-OSA
lists: APM
lists: ARIEL
lists: GENOMIZER
lists: ASP/ASPSHARE
lists: BIMBAM
lists: BIOIDE
lists: BIOLAD-DB
lists: BLADE
lists: BLOCK
lists: BOOLD
lists: BOOSTRAPPER
lists: BPPH
lists: BQTL
lists: DNABASER
lists: Calculator for Association with Two Stage design
lists: CC-QLS
lists: CCRAVAT
lists: CCREL
lists: CEPH2CRI
lists: CEPH2MAP
lists: EVOKER
lists: CFC
lists: CHECKHET
lists: MATLINK
lists: CHECKMATRIX
lists: CHIAMO
lists: CHROMOSCAN
lists: CHROMOSEG
lists: COPE
lists: HCLUST
lists: COVIBD
lists: CRIMAP-PVM
lists: CROSSFIND
lists: DGENE
lists: EHPLUS
lists: DHSMAP
lists: DISENTANGLER
lists: MAKEPED
lists: DOLINK
lists: DPPH
lists: GREGOR
lists: EAGLET
lists: EASYLINKAGE/EASYLINKAGE-PLUS
lists: EH
lists: EHAP
lists: EHP
lists: EMLD
lists: EPDT
lists: ERPA
lists: EXOMEPICKS
lists: R/META
lists: FASTEHPLUS
lists: FASTLINK
lists: FBAT
lists: FINETTI
lists: FIRSTORD
lists: FISHER
lists: GAIA
lists: GAP
lists: GAS
lists: GCHAP
lists: GDA
lists: GEMS
lists: GENECOUNTING
lists: GENEFINDER
lists: GENEHUNTER
lists: GENEHUNTER-IMPRINTING
lists: GENEHUNTER-PLUS
lists: GENEPOP
lists: GENERECON
lists: GENESPRING GT
lists: GENIE
lists: GENETIC POWER CALCULATOR
lists: GENETSIM
lists: GENOOM
lists: GENEVAR
lists: GENEWEAVER
lists: GENOCHECK
lists: GENOPROOF
lists: GENTOOLS
lists: GEST
lists: GEVALT
lists: GGT
lists: GHOST
lists: GLIDERS
lists: GLUE
lists: GMA
lists: GMCHECK
lists: GSMA
lists: GTOOL
lists: GWAPOWER
lists: HAP 2
lists: HAPAR
lists: HAPASSOC
lists: HAPBLOCK
lists: HAPGEN
lists: HAPINFERX
lists: HAPLOBLOCK
lists: HAPLOBUILD
lists: HAPLOPOOL
lists: HAPLORE
lists: HAPLO.STAT
lists: HAPLOT
lists: HAPLOTTER
lists: TWOLOC
lists: HAPLOTYPE ESTIMATION
lists: HAPLOTYPER
lists: HAPMINER
lists: HAP-SAMPLE
lists: HAPSIMU
lists: HIT
lists: HOMOG/HOMOGM
lists: HOTSPOTTER
lists: HPLUS
lists: HS-TDT
lists: HTR
lists: HTSNPER
lists: MDR-PDT
lists: INTERSNP
lists: IMPUTE
lists: NOPAR
lists: JLIN
lists: JOINMAP
lists: JPSGCS
lists: J/QTL
lists: KING
lists: LAMARC
lists: LINKAGE-IMPRINT
lists: LINKBASE
lists: LIPED
lists: LNKTOCRI
lists: LOCUSZOOM
lists: LOGINSERM ESTIHAPLO
lists: LOH-LINKAGE
lists: LOKI
lists: LOT
lists: L-POP
lists: LRP
lists: LRTAE
lists: LTSOFT
lists: MADMAPPER
lists: Marker And Gene Interpolation and Correlation
lists: MALDSOFT
lists: MAMA
lists: MANTEL-STRUCT
lists: MAP/MAP+/MAP+H/MAP2000
lists: MAPCHART
lists: MIDAS
lists: MAPDISTO
lists: MAPDRAW
lists: MAPINSPECT
lists: MAPL
lists: MARGARITA
lists: MDBLOCKS
lists: MAPMAKER/EXP
lists: MAPMAKER/HOMOZ
lists: MAPMAKER/QTL
lists: MAPQTL
lists: MCQTL
lists: MEGA2
lists: MEGASNPHUNTER
lists: MENDEL
lists: MERLIN
lists: MFLINK
lists: MINIMAC
lists: MINSAGE
lists: MITPENE
lists: MKGST
lists: MMDRAWER
lists: MLBGH
lists: MLD
lists: MLR-TAGGING
lists: PEDMANAGER
lists: SAGE
lists: MPDA
lists: MULTIDISEQ
lists: MULTIMAPPER
lists: MULTIMAPPER/OUTBRED
lists: MULTIPOPTAGSELECT
lists: MULTISIM
lists: MUTAGENESYS
lists: NOCOM
lists: NUCULAR
lists: ONEMAP
lists: OSIRIS
lists: P ACT
lists: PASS PEDIGREE
lists: PAWE
lists: PDA
lists: PDPSYS
lists: PDT
lists: PED
lists: PEDAGREE
lists: PEDCHECK
lists: PEDSTATS
lists: PEDSYS
lists: PEDVIZAPI
lists: PEER
lists: PHASE
lists: PLABSIM
lists: PL-EM
lists: POINTER
lists: POOL STR
lists: POWERMARKER
lists: POWERTRIM
lists: POWTEST
lists: PREPLINK
lists: PREST
lists: PROBMAX
lists: PROC QTL
lists: PROFILER
lists: PRT
lists: PSAT
lists: SAS/GENETICS
lists: PSEUDO
lists: PSEUDOMARKER
lists: PSEUDOMARKER.M
lists: R/LDHEATMAP
lists: QTL-ALL
lists: QTL Cartographer
lists: QTL EXPRESS
lists: QU-GENE
lists: RISCALW
lists: RC-TDT
lists: REAPER
lists: RELATIVE
lists: RELATIVEFINDER
lists: RELCHECK
lists: RELPAIR
lists: RELTYPE
lists: RHMAP
lists: ROMPREV
lists: ROSATTA SYLLEGO SYSTEM
lists: R/GAP
lists: R/HAPASSOC
lists: R/IBDREG
lists: R/LAPSTRUCT
lists: R/LDGROUP
lists: R/LUCA
lists: R/METASIM
lists: R/ONEMAP
lists: R/PIAGE
lists: R/POOLSCORE
lists: R/POPGEN
lists: R/QTLBIM
lists: R/SNP.PLOTTER
lists: SDMINP
lists: SELSIM
lists: SEQUENCE LD/SEQUENCE LDHOT
lists: SIBERROR
lists: SIBLINK
lists: SIB-PAIR
lists: SILCLOD
lists: SIMLA
lists: SNP CHART
lists: SIMLINK
lists: SIMPED
lists: SIMPLE
lists: SIMULA
lists: SIMULATE
lists: SIMUPOP
lists: SIMWALK
lists: START
lists: SKAT
lists: SLINK
lists: SMOOTH
lists: Suite of Nucleotide Analysis Programs
lists: SNAP 3
lists: SNPALYZE
lists: SNPFILE
lists: SNPLINK
lists: SNPP
lists: SNP.PLOTTER
lists: SNPTEST
lists: SPAM
lists: SPECTRAL-GEM
lists: SPERM
lists: SPIP
lists: SPLAT
lists: TAGSTER
lists: SPLINK
lists: SSAHASNP
lists: SUMSTAT
lists: SUP
lists: SWEEP
lists: TAGGER
lists: TFPGA
lists: TREESELECT
lists: UNKNOWN
lists: UTIL
lists: WHAIT
lists: ZAPLO
lists: HAPBLOCK 2
lists: PLABQTL
lists: TASSEL
lists: MCLEEPS
lists: SASGENE
lists: PANGAEA
lists: TOMCAT
lists: SCORE-SEQ
lists: SASQUANT
lists: QMSIM
lists: PIAGE
lists: PEDPACK
lists: INSEGT
lists: IBDREG
lists: GLFSINGLE/GLFTRIO/GLFMULTIPLES
lists: GGSD
lists: ECLIPSE
lists: CHROMSCAN
lists: COMPOSITELD
lists: BOOST
lists: ARP.GEE
lists: BOREL
lists: GASSOC
lists: MENDELSOFT
lists: PLINK/SEQ
lists: POLYPHEN
lists: SPREG
lists: MOLKIN
lists: PRESTO: Genetic Association Analysis Software
lists: ENDOG
lists: BEAGLECALL
lists: GWASELECT
lists: HEGESMA
lists: SNIPPEEP
lists: TAGIMPUTE
lists: SNPMSTAT
lists: SNP HITLINK
lists: MECPM
lists: R/FEST
lists: MAOS
lists: SUPERLINK
lists: PEDFIDDLER
lists: VG
lists: HAPSTAT
lists: QTDT
lists: GRIDQTL
lists: VH
lists: R/QTLDESIGN
lists: PyPop
lists: ANTMAP
lists: MDR
lists: WEIGHTED FDR
lists: THESIAS
lists: DMLE
lists: SGS
lists: BAYESFST
lists: HWMET
lists: GRR
lists: AUTOSCAN
lists: TRIMHAP
lists: ILLUMINUS
lists: PELICAN
lists: HAPLOPAINTER
lists: HOMOZYGOSITYMAPPER
lists: GERMLINE
lists: PLINK
lists: MACH 1.0
lists: BEAGLE
lists: BIRDSUITE
lists: BREAKDANCER
lists: CAROL
lists: CASAVA
lists: CYRILLIC
lists: DINDEL
lists: GenABEL
lists: GATK
lists: PEDIGRAPH
lists: MADELINE
lists: METAL
lists: OLORIN
lists: PEDHUNTER
lists: POLYMUTT
lists: SAMTOOLS
lists: SNAP - SNP Annotation and Proxy Search
lists: STRUCTURE
lists: SVA
lists: SYZYGY
lists: VAAST
lists: Hapmix
lists: Ancestrymap
lists: Hmmer
lists: PROGENY
lists: VarScan
lists: MORGAN
lists: CMAP
lists: SIMHAP
lists: SIFT
lists: ANNOVAR
lists: Body Mass Index Calculator
lists: PolyPhen: Polymorphism Phenotyping
has parent organization: Feinstein Institute for Medical Research
has parent organization: Iowa State University; Iowa; USA
THIS RESOURCE IS NO LONGER IN SERVICE nif-0000-33506 http://lab.rockefeller.edu/ott/geneticsoftware http://linkage.rockefeller.edu/soft/ SCR_013155 An Alphabetic List of Genetic Analysis Software 2026-09-12 12:57:59 9
ARP.GEE
 
Resource Report
Resource Website
1+ mentions
ARP.GEE (RRID:SCR_013134) software application, software resource THIS RESOURCE IS NO LONGER IN SERVICE. Documented on May 24,2023. Software application that simultaneously estimates a trait-locus position and its genetic effects for affected relative pairs (ARP) by one of two methods. Either allow a different trait-locus effect for each ARP type, or constrain the trait-locus effects according to the marginal effect of a single susceptibility locus. We include a goodness of fit statistic for the constrained model. (entry from Genetic Analysis Software) gene, genetic, genomic, r/s-plus is listed by: Genetic Analysis Software THIS RESOURCE IS NO LONGER IN SERVICE nlx_154206, SCR_009108, nlx_154232 SCR_013134 R/ARP.GEE 2026-09-12 12:57:59 7
PolyPhen: Polymorphism Phenotyping
 
Resource Report
Resource Website
1000+ mentions
PolyPhen: Polymorphism Phenotyping (RRID:SCR_013189) PolyPhen, PolyPhen-2, POLYPHEN data analysis software, data processing software, simulation software, software application, software resource Software tool which predicts possible impact of amino acid substitution on structure and function of human protein using straightforward physical and comparative considerations. PolyPhen-2 is new development of PolyPhen tool for annotating coding nonsynonymous SNPs. annotate, nonsynonymous, SNP, predict, coding, damaging, effect, missense, mutation, sequence, variant, phenotype, genetic, disease, exon, protein, coding, fraction, genome, bio.tools is listed by: Genetic Analysis Software
is listed by: Debian
is listed by: bio.tools
is related to: OMICtools
has parent organization: Harvard University; Cambridge; United States
PMID:20354512
PMID:23315928
SCR_013200, OMICS_00136, nlx_154540, nif-0000-21329, biotools:polyphen, SCR_013238 https://bio.tools/polyphen http://www.bork.embl-heidelberg.de/PolyPhen/ SCR_013189 PolyPhen, POLYPHEN, PolyPhen-2, Polymorphism Phenotyping, Polymorphism Phenotyping v2 2026-09-12 12:58:00 4723
eQTL Visualization Tool
 
Resource Report
Resource Website
1+ mentions
eQTL Visualization Tool (RRID:SCR_013413) data processing software, data visualization software, software application, software resource THIS RESOURCE IS NO LONGER IN SERVICE. Documented on June 1,2023. eQTL Explorer was developed as a computational resource to visualize and explore data from combined genome-wide expression and linkage studies is essential for the development of testable hypotheses. This visualization tool stores expression profiles, linkage data and information from external sources in a relational database and enables simultaneous visualization and intuitive interpretation of the combined data via a Java graphical interface. eQTL Explorer also provides a new and powerful tool to interrogate these very large and complex datasets. eQTLexplorer allows users to mine and understand data from a repository of genetical genomics experiments. It will graphically display eQTL information based on a certain number of selection criteria, including: tissue type, p-value, cis/trans, probeset Affymetrix id and PQTL type. Sponsors: This work was funded by the MRC Clinical Sciences Centre and the Wellcome Trust programme for Cardiovascular Functional Genomics. experiment, explore, expression, genome, genetic, genetical, cis, computational, data, database, genomic, grafical, interface, linkage, mine, pqtl type, p-value, repository, tissue, tissue type, trans, visualization, visualize THIS RESOURCE IS NO LONGER IN SERVICE nif-0000-10222 SCR_013413 eQTLexplorer 2026-09-12 12:58:03 1
SIFT
 
Resource Report
Resource Website
10000+ mentions
SIFT (RRID:SCR_012813) SIFT analysis service resource, data access protocol, data analysis service, production service resource, service resource, software resource, source code, web service Data analysis service to predict whether an amino acid substitution affects protein function based on sequence homology and the physical properties of amino acids. SIFT can be applied to naturally occurring nonsynonymous polymorphisms and laboratory-induced missense mutations. (entry from Genetic Analysis Software) Web service is also available. gene, genetic, genomic, amino acid, substitution, protein function, coding region, single nucleotide variant, coding indel, deletion, insertion, sequence, protein, bio.tools is listed by: OMICtools
is listed by: Genetic Analysis Software
is listed by: Debian
is listed by: bio.tools
is listed by: SoftCite
is related to: SIFT 4G
has parent organization: Genome Institute of Singapore; Singapore; Singapore
has parent organization: J. Craig Venter Institute
Agency for Science Technology and Research ;
NIGMS GM29009
PMID:19561590
PMID:12824425
PMID:11337480
DOI:10.1038/nprot.2009.86
Non-commercial biotools:sift, OMICS_00137, nlx_154618 http://sift.jcvi.org/, https://bio.tools/sift, https://sources.debian.org/src/sift/ http://sift.bii.a-star.edu.sg/SIFT.html SCR_012813 Sorting Intolerant From Tolerant 2026-09-12 12:57:53 10996
Rice Proteome Database
 
Resource Report
Resource Website
1+ mentions
Rice Proteome Database (RRID:SCR_000743) data or information resource, database THIS RESOURCE IS NO LONGER IN SERVICE, documented July 22, 2016.

A database on the proteome of rice that contains reference maps based on two-dimensional polyacrylamide gel electrophoresis (2D-PAGE) of proteins from rice tissues and subcellular compartments.
rice, proteome, gene, genetic, eleoctrophoresis, 2d-page, tissue, subcellular compartments has parent organization: National Institute of Agrobiological Sciences; Ibaraki; Japan PMID:16217611 THIS RESOURCE IS NO LONGER IN SERVICE nif-0000-03409 http://dbarchive.biosciencedbc.jp/en/rpd/desc.html SCR_000743 2026-09-12 01:01:20 2
NHGRI Dog Genome Project
 
Resource Report
Resource Website
1+ mentions
NHGRI Dog Genome Project (RRID:SCR_002256) NHGRI Dog Genome Project data or information resource, database The Dog Genome Project at the National Human Genome Research Institute is working to develop resources necessary to map and clone canine genes in an effort to utilize dogs as a model system for genetics and cancer research. The US National Human Genome Research Institute (NHGRI) agreed to fund a project to sequence the entire genome of a boxer dog named Tasha, because it recognized the value of the dog as an unrivaled model for the study of human disease. The National Human Genome Research Institute (NHGRI) led the National Institutes of Health's (NIH) contribution to the International Human Genome Project, which had as its primary goal the sequencing of the human genome. This project was successfully completed in April 2003. Now, the NHGRI's mission has expanded to encompass a broad range of studies aimed at understanding the structure and function of the human genome and its role in health and disease. To that end NHGRI supports the development of resources and technology that will accelerate genome research and its application to human health. A critical part of the NHGRI mission continues to be the study of the ethical, legal and social implications (ELSI) of genome research. NHGRI also supports the training of investigators and the dissemination of genome information to the public and to health professionals. gene, genetic, cancer, canine, clone, disease, dog, genome, health, human, map, model, system PMID:16102268 nif-0000-20975 SCR_002256 National Human Genome Research Institute Dog Genome Project 2026-09-12 01:01:25 1
German Collection of Microorganisms and Cell Cultures
 
Resource Report
Resource Website
100+ mentions
German Collection of Microorganisms and Cell Cultures (RRID:SCR_001711) DSMZ data or information resource, database The DSMZ - Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH (German Collection of Microorganisms and Cell Cultures) is the most comprehensive biological resource center in Europe. With more than 18.000 microorganisms, 1.200 plant viruses, 600 human and animal cell lines, 770 plant cell cultures and more than 7.100 cultures deposited for the purposes of patenting, DSMZ has demonstrated their obligation to serve science for decades. Main functions of DSMZ are: - to collect, maintain and store microorganisms and cell lines, as well as other biological material of relevance for applied biology, biotechnology, microbiology, teaching and other areas of research and general application; - to keep the scientific and industrial community informed on the contents of the collections by the means of catalogs, special lists, databases or electronic media; - to supply scientists and institutions with DSMZ cultures, in accordance with national and international laws such as the Infektionsschutzgesetz (Act dealing with protection against infection), the Genetic Engineering Act, the Foreign Trade Laws, the Convention on Biological Diversity as well as the DSMZ terms of supply; - to function as an internationally recognized collection center for the deposit of microorganisms, cell lines, and other biological material which have been cited in scientific literature or which are used in national or international test procedures (e.g. type strains, reference strains for national and international quality control regulations or susceptibility tests, strains with special properties, such as the production of enzymes, degradation of pollutants, host strains for plasmids, etc.); - to act as an International Depositary Authority (IDA) for the deposit of biological material for patent purposes according to the Budapest Treaty; - to act, in a confidential manner, as a center for the safe deposit of biological material; - to act as an advisory center for the scientific community and to offer teaching and service facilities. The DSMZ collections contain over 26 000 cultures (including 6500 patent deposits) representing more than 16 000 cultures of microorganisms (Archaea, Bacteria, plasmids, phages, yeasts, fungi), 750 plant cell cultures, 600 plant viruses, 700 antisera and 580 human and animal cell lines. Unique subcollections are held in the prokaryotes groups of acidophiles, alkaliphiles, halophiles, methanogens, phototrophs, thermophiles, and sulfate reducers. The research is focused on collection related fields which include: - Taxonomy - Evolution - Phylogeny - Microbial diversity and molecular assessment of diversity - Molecular systematics - Research on pathobiological aspects of leukemia-lymphoma cell lines applying classical and molecular genetics, immunological and cell biological methods * Development of cultivation and preservation methods for biological material * Characterization and identification of biological material enzyme, europe, evolution, fungus, genetic, acidophile, alkaliphile, animal, antisera, archaea, bacteria, biological, biology, biotechnology, cell, cell culture, culture, degradation, diversity, halophile, host, human, human cell line, immunological, leukemia, literature, lymphoma, methanogen, microbial, microbiology, microorganism, molecular, pathobiological, phage, phototroph, phylogeny, plant, plant virus, plasmid, pollutant, prokaryote, reducer, research, science, scientific, strain, sulfate, systematic, taxonomy, thermophile, virus, yeast, FASEB list is listed by: DataCite
is listed by: re3data.org
is parent organization of: SILVA
works with: Cellosaurus
PMID:18080463 Free, Freely Available DOI:10.17616/R3G88X, nif-0000-10209, r3d100010219, DOI:10.13145 https://doi.org/10.17616/R3G88X, https://doi.org/10.17616/r3G88X, https://doi.org/10.13145/, https://dx.doi.org/10.13145/, https://doi.org/10.17616/R3G88X SCR_001711 Leibniz Institut DSMZ - Deutsche Sammlung von Mikroorganismen und Zellkulturen GmbH, Leibniz Institute DSMZ - German Collection of Microorganisms and Cell Cultures 2026-09-12 01:01:23 424
WD repeat Family of Proteins
 
Resource Report
Resource Website
WD repeat Family of Proteins (RRID:SCR_002160) data or information resource, database THIS RESOURCE IS NO LONGER IN SERVICE, documented on August 26, 2016. This website contains a library of WD-repeat containing proteins in which the repeats appear as multi-aligned sets. WD-repeat-containing proteins are those that contain 4 or more copies of the WD-repeat (tryptophan-aspartate repeat), a sequence motif approximately 31 amino acids long, that encodes a structural repeat. This repeat is described by the following profile, where x is ANY amino acid. By clicking on each high-lighted character you will obtain the distribution of amino acids found at that position of the repeat among an aligned set of WD-repeat containing proteins. The tertiary structure of only one member of this family has been determined, that of the G protein beta subunit, which contains 7 WD-repeats. Each of the 7 repeats folds into a small antiparallel beta-sheet. The over-lines above indicate the position of these strands, with a being the strand closest to the central pore and d at the external surface of the folded protein. These sheets are arranged around a central pseudosymmetry axis into a beta propeller. The WD-repeat-containing proteins form a very large family that is diverse in both its function and domain structure. Within all these proteins the WD-repeat domains are thought to have two common features: the domain folds into a beta propeller; and the domains form a platform without any catalytic activity on which multiple protein complexes assemble reversibly. The fact that these proteins play such key roles in the formation of protein-protein complexes in nearly all the major pathways and organelles unique to eukaryotic cells has two important implications. It supports both their ancient and proto eukaryotic origins and supports a likely association with many genetic diseases. eukaryotic, function, genetic, align, amino acid, ancient, antiparallel, aspartate, beta, cell, disease, domain, g protein, multi-aligned, organelle, origin, pathway, propeller, protein, proto, pseudosymmetry, sheet, structural, tertiary, tryptophan, wd-repeat THIS RESOURCE IS NO LONGER IN SERVICE nif-0000-20949 SCR_002160 WD repeat Family of Proteins 2026-09-12 01:01:24 0
Interaction Reference Index
 
Resource Report
Resource Website
10+ mentions
Interaction Reference Index (RRID:SCR_002085) iRefIndex data or information resource, database An index of protein interactions available in a number of primary interaction databases including BIND, BioGRID, CORUM, DIP, HPRD, IntAct, MINT, MPact, MPPI and OPHID. This index includes multiple interaction types including physical and genetic (mapped to their corresponding protein products) as determined by a multitude of methods. This index allows the user to search for a protein and retrieve a non-redundant list of interactors for that protein. iRefIndex uses the Sequence Global Unique Identifier (SEGUID) to group proteins and interactions into redundant groups. This method allows users to integrate their own data with the iRefIndex in a way that ensures proteins with the exact same sequence will be represented only once. iRefIndex project has three long term objectives: # to facilitate exchange of interaction data between interaction databases. # to consolidate interaction data from multiple sources. # to provide feedback to source interaction databases. iRefIndex is made available in a number of formats: MITAB tab-delimited text files, iRefWeb interface, iRefScape plugin for Cytoscape, PSICQUIC Web services, and an interface for the R programming language environment. genetic, interaction, protein, protein interaction, protein-protein interaction is related to: BIND
is related to: Biological General Repository for Interaction Datasets (BioGRID)
is related to: CORUM
is related to: Database of Interacting Proteins (DIP)
is related to: HPRD - Human Protein Reference Database
is related to: InnateDB
is related to: IntAct
is related to: MatrixDB
is related to: MINT
is related to: MPact: Representation of Interaction Data at MIPS
is related to: MPIDB
is related to: MIPS Mammalian Protein-Protein Interaction Database
is related to: I2D
is related to: IMEx - The International Molecular Exchange Consortium
is related to: PSICQUIC Registry
PMID:18823568 THIS RESOURCE IS NO LONGER IN SERVICE nif-0000-20860 http://irefindex.uio.no SCR_002085 2026-09-12 01:01:23 22
GeneCards
 
Resource Report
Resource Website
5000+ mentions
GeneCards (RRID:SCR_002773) GeneCards data or information resource, database Database of human genes that provides concise genomic, proteomic, transcriptomic, genetic and functional information on all known and predicted human genes. Information featured in GeneCards includes orthologies, disease relationships, mutations and SNPs, gene expression, gene function, pathways, protein-protein interactions, related drugs and compounds and direct links to cutting edge research reagents and tools such as antibodies, recombinant proteins, clones, expression assays and RNAi reagents. genome, human gene, genome, gene, genomic, proteomic, transcriptomic, genetic, function, ortholog, disease, mutation, single nucleotide polymorphism, gene expression, gene function, pathway, protein-protein interaction, drug, compound, reagent, antibody, recombinant protein, clone, expression assay, rnai reagent, FASEB list is listed by: OMICtools
is related to: MOPED - Model Organism Protein Expression Database
PMID:20689021 Free, Freely available nif-0000-02879, OMICS_01652, r3d100012015 http://bioinfo.weizmann.ac.il/genecards/, https://doi.org/10.17616/R3D643 SCR_002773 GeneCards - The Human Gene Compendium 2026-09-12 01:01:26 7635
LINCS Connectivity Map
 
Resource Report
Resource Website
500+ mentions
LINCS Connectivity Map (RRID:SCR_002639) CMap data or information resource, database A catalog of gene-expression data collected from human cells treated with chemical compounds and genetic reagents. Computational methods to reduce the number of necessary genomic measurements along with streamlined methodologies enable the current effort to significantly increase the size of the CMap database and along with it, our potential to connect human diseases with the genes that underlie them and the drugs that treat them. The NIH has funded a large expansion of the Connectivity Map dataset through the Library of Integrated Network-based Cellular Signatures (LINCS). The Broad Institute's LINCS center aims to create a first installment of data generation and analysis for the LINCS program. Through these data LINCS intends to accelerate the discovery process by systematically revealing connections between genes/compounds discovered in screens and molecular pathways that underlie disease states. functional genomics, gene, cell, gene expression, compound, molecule, pathway, disease, perturbagen, gene expression profile, genetic, cellular, chemical reagent, FASEB list has parent organization: Broad Institute
has parent organization: HMS LINCS Database
NIH Common Fund PMID:28069634 Free, Freely available nlx_156066 SCR_002639 Connectivity Map 2026-09-12 01:01:26 650
Hapmix
 
Resource Report
Resource Website
50+ mentions
Hapmix (RRID:SCR_004203) HAPMIX software application, software resource, source code Software application that uses genotyping data from SNP arrays for accurately inferring chromosomal segments of distinct continental ancestry in admixed populations, using dense genetic data. (entry from Genetic Analysis Software) gene, genetic, genomic, admixed, population, genotype, single nucleotide polymorphism, ancestry, chromosomal segment, snp array is listed by: OMICtools
is listed by: Genetic Analysis Software
has parent organization: Harvard Medical School; Massachusetts; USA
NHGRI U01-HG004168;
NHLBI R01-HL087699
PMID:19543370 Restricted nlx_22768, OMICS_02082 http://www.hsph.harvard.edu/faculty/alkes-price/software/, http://www.stats.ox.ac.uk/~myers/software.html, https://reich.hms.harvard.edu/software http://genetics.med.harvard.edu/reich/Reich_Lab/Software.html SCR_004203 2026-09-12 01:01:30 52
Hungarian Neurological-Psychiatric Biobank
 
Resource Report
Resource Website
Hungarian Neurological-Psychiatric Biobank (RRID:SCR_003715) NEPSYBANK biomaterial supply resource, material resource, tissue bank The Hungarian Society of Clinical Neurgenetics established a nationwide collaboration for prospective collection of human biological materials and databases from patient with neurological and psychiatric diseases. The basic triangle of the NEPSYBANK is the sample, the information and the study management. The present participants of the NEPSYBANK are the Department of Neurology and Psychiatry of the four Medical Universities (in Budapest, Debrecen, Pecs, Szeged) and the National Institute of Psychiatry and Neurology in Budapest. The NEPSYBANK is a disease based biobank collecting both phenotypical and environmental data and biological materials such as DNA/RNA, whole blood, plasma, cerebral spinal fluid, muscle / nerve / skin biopsy, brain, and fibroblast. The target of the diseases is presently (Phase I): stroke syndromes, dementias, movement disorders, motoneuron diseases, epilepsy, multiple sclerosis, schizophrenia, alcohol addiction. In the near future (Phase II.) it is planned to enlarge the scale with headaches, disorders of the peripheral nerves, disorders of neuromuscular transmission, disorders of skeletal muscle, depression, anxiety. DNA/RNA is usually extracted from whole blood, but occasionally different tissues such as muscle, brain etc. can be used as well. The extracting procedures differ among the institutes, but in all cases the concentration and the quality of the DNA/RNA must be registered in the database. Participating institutional biobanks have committed themselves to follow common quality standards, which provide access to samples after prioritization on scientific grounds only. In every case the following data are registered. 1. General data: main bank categories, age, sex, ethnicity, body height, body weight, economic stats, education, type of place of living, marital status, birth complications, alcohol, drugs, smoking. 2. Sample properties (sample ID, type of sample, date of extraction, concentration, and level of purity). General patient data as blood pressure, heart rate, internal medical status, ECG, additional diseases. Disease specific question e.g. in schizophrenia the diagnosis after DSMIV and ICD 10, detailed diagnostic questions after both classification, detailed psychiatric and neurological status, laboratory findings, rating scales, data of neuroimaging, genetic tests, applied medication (with generic name, dose, duration), adverse drug effects and other treatments. The Biobank Information Management System (BIMS) is responsible for linkage of databases containing information on the individual sample donors. If you want to have samples from the NEPSYBANK an application must be submitted containing the following information: short research plan including aims and study design, ethic application with a positive decision, specific demands regarding the right of disposition, agreements with grant organizations which regulate immaterial property, information about financing (academic grants, support from industry). All participants have the right to withdraw their samples through a simple order. neurology, psychiatry, genomic, gene, genetic, disease, phenotype, clinical data, environment, dna, rna, whole blood, plasma, cerebral spinal fluid, muscle, biopsy, nerve, skin, brain, fibroblast, tissue, blood, frozen, liquid nitrogen, neurological disease, psychiatric disease, stroke, dementia, movement disorder, motor neuron disease, epilepsy, multiple sclerosis, schizophrenia, alcohol, addiction, alcohol addiction, headache, peripheral nerve disorder, neuromuscular transmission disorder, skeletal muscle disorder, depressive disorder, anxiety is listed by: One Mind Biospecimen Bank Listing Neurological disease, Psychiatric disease, Stroke, Dementia, Movement disorder, Motor Neuron Disease, Epilepsy, Multiple Sclerosis, Schizophrenia, Alcohol addiction, Headache, Peripheral nerve disorder, Neuromuscular transmission disorder, Skeletal muscle disorder, Depressive Disorder, Anxiety PMID:17448454 Public: if you want to have samples from the NEPSYBANK an application must be submitted. nlx_13478 SCR_003715 Hungarian Neurological - Psychiatric Biobank, Hungarian Neurological - Psychiatric Biobank - NEPSYBANK 2026-09-12 01:01:29 0
Wiring the Brain
 
Resource Report
Resource Website
Wiring the Brain (RRID:SCR_005528) Wiring the Brain blog, data or information resource, narrative resource This blog highlights and comments on current research and hypotheses relating to how the brain wires itself up during development, how the end result can vary in different people and what happens when it goes wrong. It includes discussions of the genetic and neurodevelopmental bases of traits such as intelligence and personality characteristics, as well as of conditions such as schizophrenia, autism, dyslexia, epilepsy, synaesthesia and others. research, brain, development, genetic, wiring, neurodevelopment, trait, intelligence, personality, schizophrenia, autism, dyslexia, epilepsy, synaesthesia Schizophrenia, Autism, Dyslexia, Epilepsy, Synaesthesia, Etc. nlx_144622 SCR_005528 2026-09-12 01:01:38 0
Stroke Patient Recovery Research Database (SPReD)
 
Resource Report
Resource Website
Stroke Patient Recovery Research Database (SPReD) (RRID:SCR_005508) SPReD data or information resource, database, image THIS RESOURCE IS NO LONGER IN SERVICE. Documented on January 28,2025. The Stroke Patient Recovery Research Database (SPReD) initiative creates the infrastructure needed for the collection of a wide range of data related to stroke risk factors and to stroke recovery. It also promotes the analysis and management of large brain and vessel images. A major goal is to create a comprehensive electronic database Stroke Patient Recovery Research Database or SPReD and populate it with patient data, including demographic, biomarker, genetic and proteomic data and imaging data. SPReD will enable us to combine descriptions of our stroke patients from multiple projects that are geographically distributed. We will do this in a uniform fashion in order to enhance our ability to document rates of recovery; to study the effects of vascular risk factors and inflammatory biomarkers; and to use these data to improve their physical and cognitive recovery through innovative intervention programs. This comprehensive database will provide an integrated repository of data with which our researchers will investigate and test original ideas, ultimately leading to knowledge that can be applied clinically to benefit stroke survivors. stroke, demographic, biomarker, genetic, proteomic, imaging, clinical, brain, vessel, risk factor, recovery THIS RESOURCE IS NO LONGER IN SERVICE nlx_144609 SCR_005508 Stroke Patient Recovery Research Database 2026-09-12 01:01:38 0
Center for Computational Biology at UCLA
 
Resource Report
Resource Website
Center for Computational Biology at UCLA (RRID:SCR_000334) CCB, UCLA CCB, USC CCB data or information resource, organization portal, portal THIS RESOURCE IS NO LONGER IN SERVICE. Documented on August 31, 2022. Center focused on the development of computational biological atlases of different populations, subjects, modalities, and spatio-temporal scales with 3 types of resources: (1) Stand-alone computational software tools (image and volume processing, analysis, visualization, graphical workflow environments). (2) Infrastructure Resources (Databases, computational Grid, services). (3) Web-services (web-accessible resources for processing, validation and exploration of multimodal/multichannel data including clinical data, imaging data, genetics data and phenotypic data). The CCB develops novel mathematical, computational, and engineering approaches to map biological form and function in health and disease. CCB computational tools integrate neuroimaging, genetic, clinical, and other relevant data to enable the detailed exploration of distinct spatial and temporal biological characteristics. Generalizable mathematical approaches are developed and deployed using Grid computing to create practical biological atlases that describe spatiotemporal change in biological systems. The efforts of CCB make possible discovery-oriented science and the accumulation of new biological knowledge. The Center has been divided into cores organized as follows: - Core 1 is focused on mathematical and computational research. Core 2 is involved in the development of tools to be used by Core 3. Core 3 is composed of the driving biological projects; Mapping Genomic Function, Mapping Biological Structure, and Mapping Brain Phenotype. - Cores 4 - 7 provide the infrastructure for joint structure within the Center as well as the development of new approaches and procedures to augment the research and development of Cores 1-3. These cores are: (4)Infrastructure and Resources, (5) Education and Training, (6) Dissemination, and (7) Administration and Management. The main focus of the CCB is on the brain, and specifically on neuroimaging. This area has a long tradition of sophisticated mathematical and computational techniques. Nevertheless, new developments in related areas of mathematics and computational science have emerged in recent years, some from related application areas such as Computer Graphics, Computer Vision, and Image Processing, as well as from Computational Mathematics and the Computational Sciences. We are confident that many of these ideas can be applied beneficially to neuroimaging. functional, genetic, biological system, brain, clinical, computational, computational mathematic, disease, health, image processing, physiological, population, structural, neuroimaging, computational neuroscience, imaging genomics, magnetic resonance, pet, spect is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC)
is related to: National Centers for Biomedical Computing
has parent organization: Laboratory of Neuro Imaging
NCRR U54 RR021813 PMID:22081221 THIS RESOURCE IS NO LONGER IN SERVICE nif-0000-10492 http://ccb.loni.ucla.edu/ http://www.nitrc.org/projects/ccb, http://cms.loni.ucla.edu/CCB/ SCR_000334 CCB at UCLA, Center for Computational Biology 2026-09-12 01:00:51 0
Tennenbaum Center for the Biology of Creativity
 
Resource Report
Resource Website
Tennenbaum Center for the Biology of Creativity (RRID:SCR_000668) data or information resource, organization portal, portal The purpose of this center is to study the molecular, cellular, systems and cognitive mechanisms that result in cognitive enhancements and explain unusual levels of performance in gifted individuals, including extraordinary creativity. Additionally, by understating the mechanisms responsible for enhancements in performance we may be better suited to intervene and reverse disease states that result in cognitive deficits. One of the key topics addressed by the Center is the biological basis of cognitive enhancements, a topic that can be studied in human subjects and animal models. In the past much of the focus in the brain sciences has been on the study of brain mechanisms that degrade cognitive performance (for example, on mutations or other lesions that cause cognitive deficits). The Tennenbaum Center for the Biology of Creativity at UCLA enables an interdisciplinary team of leading scientists to advance knowledge about the biological bases of creativity. Starting with a pilot project program, a series of investigations was launched, spanning disciplines from basic molecular biology to cognitive neuroscience. Because the concept of creativity is multifaceted, initial efforts targeted refinement of the component processes necessary to generate novel, useful cognitive products. The identified core cognitive processes: 1.) Novelty Generation the ability to flexibly and adaptively generate products that are unique; 2.) Working Memory and Declarative Memory the ability to maintain, and then use relevant information to guide goal-directed performance, along with the capacity to store and retrieve this information; and 3.) Response Inhibition the ability to suppress habitual plans and substitute alternate actions in line with changing problem-solving demands. To study the basic mechanisms underlying these complex brain functions we use translational strategies. Starting from foundational studies in basic neuroscience, we forged an interdisciplinary strategy that permits the most advanced techniques for genetic manipulation and basic neurobiological research to be applied in close collaboration with human studies that converge on the same core cognitive processes. Our integrated research program aims to reveal the genetic architecture and fundamental brain mechanisms underlying creative cognition. The work holds enormous promise for both enhancing healthy cognitive performance and designing new treatments for diverse cognitive disorders. Sponsors: The Tennenbaum Center for the Biology of Creativity was inspired by the vision and generosity of Michael Tennenbaum. generation, genetic, animal, biological, brain, brain science, cellular, cognitive, cognitive deficit, cognitive disorder, cognitive neuroscience, creativity, declarative memory, disease, habitual, human, inhibition, mechanism, memory, model, molecular, molecular biology, neurobiological, performance, response, working memory THIS RESOURCE IS NO LONGER IN SERVICE nif-0000-10497 SCR_000668 UCLA CBC 2026-09-12 01:00:51 0

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