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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Specification URL Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
BioPlex
 
Resource Report
Resource Website
1000+ mentions
BioPlex (RRID:SCR_016144) data or information resource, data repository, database, service resource, storage service resource Database of cell lines with each expressing a tagged version of a protein from the ORFeome collection. The overarching project goal is to determine protein interactions for every member of the collection. cell, line, protein, immunopurification, mass, spectrometry, interaction, bio.tools, FASEB list is listed by: bio.tools
is listed by: Debian
has parent organization: Harvard Medical School; Massachusetts; USA
Canadian Institutes for Health Research ;
NHGRI U41HG006673;
NIDDK K01 DK098285
PMID:28514442 biotools:bioplex_2.0 https://bio.tools/bioplex_2.0 SCR_016144 BioPlex (biophysical interactions of ORFeome-based complexes), Harvard BioPlex, Biophysical Interactions of Orfeome-based comPLEXes (BioPLEX) 2026-08-29 11:25:32 1378
mentha
 
Resource Report
Resource Website
100+ mentions
mentha (RRID:SCR_016148) data analysis software, data or information resource, data processing software, database, software application, software resource, web application Software that archives evidence collected from different sources, then analyzes and presents these data. Its data come from manually curated protein-protein interaction databases that have adhered to the IMEx consortium. protein, ppi, imex, interactome, archival, bio.tools, FASEB list uses: PSICQUIC Registry
is listed by: Debian
is listed by: bio.tools
is related to: IMEx - The International Molecular Exchange Consortium
PMID:23900247 biotools:mentha, r3d100011124 https://bio.tools/mentha, https://doi.org/10.17616/R3SP8V SCR_016148 2026-08-29 11:25:32 156
Exonerate
 
Resource Report
Resource Website
100+ mentions
Exonerate (RRID:SCR_016088) alignment software, data processing software, image analysis software, software application, software resource, software toolkit Software package for sequence alignment of pairwise sequence comparison. Exonerate can be used to align sequences using many alignment models, exhaustive dynamic programming, or a variety of heuristics., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. sequence, alignment, pairwise, comparison, dynamic, programming, heuristic, bio.tools is used by: ExonerateTransferAnnotation
is listed by: Debian
is listed by: bio.tools
has parent organization: Wellcome Trust Sanger Institute; Hinxton; United Kingdom
PMID:15713233 THIS RESOURCE IS NO LONGER IN SERVICE biotools:exonerate https://bio.tools/exonerate SCR_016088 2026-08-29 11:25:12 376
Necklace
 
Resource Report
Resource Website
1+ mentions
Necklace (RRID:SCR_016103) alignment software, data processing software, image analysis software, software application, software resource Software that combines reference and assembled transcriptomes for RNA-Seq analysis. It replaces many manual steps in the pipeline of RNA-Seq analyses involving species with incomplete genome or annotations. RNA, Transcriptome, Non-model species, bio.tools is listed by: bio.tools
is listed by: Debian
PMID:28836999 Free, Available for download biotools:necklace https://bio.tools/necklace SCR_016103 Lace software 2026-08-29 11:25:12 3
BLINK
 
Resource Report
Resource Website
1+ mentions
BLINK (RRID:SCR_016288) algorithm resource, data analysis software, data processing software, software application, software resource Software for next level of genome wide association studies with both individuals and markers in millions. The method releases the requirement that causative genes are evenly distributed on genome and consequently boosts statistical power. GWAS, SNP, dataset, r, genome, bayesian, linkage, nested, keyway, statistic, bio.tools is listed by: Debian
is listed by: bio.tools
Free, Available for download, Tutorial available biotools:BLINK https://bio.tools/BLINK SCR_016288 BLINK (Bayesian-information and Linkage-disequilibrium Iteratively Nested Keyway) 2026-08-29 11:25:16 2
MetaCyto
 
Resource Report
Resource Website
1+ mentions
MetaCyto (RRID:SCR_016415) data analysis software, data processing software, software application, software resource, software toolkit Software tool for automated meta-analysis of mass and flow cytometry data. Provides functions for preprocessing, automated gating and meta-analysis of cytometry data and collection of cytometry data from the ImmPort database. automated, analysis, meta, flow, cytometry, data, bio.tools is listed by: Bioconductor
is listed by: NIDDK Information Network (dkNET)
is listed by: bio.tools
is listed by: Debian
is related to: The Immunology Database and Analysis Portal (ImmPort)
the National Institute of Allergy and Infectious Diseases HHSN272201200028C Free, Available for download, Freely available biotools:metacyto https://bio.tools/metacyto SCR_016415 2026-08-29 11:25:43 5
SMAGEXP
 
Resource Report
Resource Website
1+ mentions
SMAGEXP (RRID:SCR_016360) SMAGEXP data analysis software, data processing software, software application, software resource, software toolkit Software toolkit for transcriptomics data meta-analysis. It integrates metaMA and metaRNAseq packages into Galaxy, carries out meta-analysis of gene expression data, handles microarray data from Gene Expression Omnibus (GEO) database, and more. transcriptomics, data, meta, analysis, MicroArrays, RNA-Seq, Galaxy, gene, expression, next, generation, sequencing, bio.tools is listed by: Debian
is listed by: bio.tools
is related to: Galaxy
is related to: Gene Expression Omnibus
is related to: metaMA
is related to: metaRNASeq
PMID:30698691 Free, Available for download, Freely available biotools:SMAGEXP https://bio.tools/SMAGEXP SCR_016360 Statistical Meta Analysis for Gene EXPression 2026-08-29 11:25:40 2
FluxModeCalculator
 
Resource Report
Resource Website
1+ mentions
FluxModeCalculator (RRID:SCR_016290) data analysis software, data processing software, software application, software resource Software for performing flux mode analysis in stoichiometric models. FluxModeCalculator enables large-scale elementary flux mode (EFM) computation and uses the OpenMP API to optimally exploit processor architectures with multiple cores., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. efm, flux, stoichiometry, algorithm, matlab, linux, model, magnitude, bio.tools is listed by: Debian
is listed by: bio.tools
Biobanking and Biomolecular Resources Research Infrastructure (BBMRI) ;
CardioVascular Research Netherlands (CVON-ENERGISE) ;
Center of Medical Systems Biology (CMSB) ;
European Network for Genetic and Genomic Epidemiology (ENGAGE) ;
Netherlands Consortium for Systems Biology (NCSB)
PMID:26685305 THIS RESOURCE IS NO LONGER IN SERVICE biotools:fluxmodecalculator, OMICS_10894 https://bio.tools/fluxmodecalculator SCR_016290 Flux Mode Calculator 2026-08-29 11:25:37 1
Knime4Bio
 
Resource Report
Resource Website
1+ mentions
Knime4Bio (RRID:SCR_005376) Knime4Bio software resource A set of custom nodes for the KNIME (The Konstanz Information Miner) graphical workbench, for analysing next-generation sequencing (NGS) data without the requirement of programming skills. node, next-generation sequencing, knime, bioinformatics, workflow, sequencing, flow, data, bam, wig, bed, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: Google Code
PMID:21984761 GNU General Public License, v3 biotools:knime4bio, OMICS_01143 https://bio.tools/knime4bio SCR_005376 Knime4Bio: custom nodes for the interpretation of Next Generation Sequencing data with KNIME 2026-08-29 11:22:13 2
PhenoMan
 
Resource Report
Resource Website
1+ mentions
PhenoMan (RRID:SCR_005249) PhenoMan software resource An interactive software program that integrates phenotypic data exploration, selection, management and quality control using a unified platform for association studies of rare and common variants. phenotype, quality control, statistical genetics, association study, python, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: Google Code
has parent organization: Baylor University; Texas; USA
GNU General Public License, v3 biotools:phenoman, OMICS_00301 https://bio.tools/phenoman SCR_005249 phenoman - Phenotypic data exploration selection management and quality control for association studies of rare and common variants 2026-08-29 11:22:17 1
KGGSeq
 
Resource Report
Resource Website
50+ mentions
KGGSeq (RRID:SCR_005311) KGGSeq software resource A biological Knowledge-based mining platform for Genomic and Genetic studies using Sequence data. The software platform, constituted of bioinformatics and statistical genetics functions, makes use of valuable biologic resources and knowledge for sequencing-based genetic mapping of variants / genes responsible for human diseases / traits. It facilitates geneticists to fish for the genetic determinants of human diseases / traits in the big sea of DNA sequences. KGGSeq has paid attention to downstream analysis of genetic mapping. The framework was implemented to filter and prioritize genetic variants from whole exome sequencing data. genomic, genetic, sequence, mutation, exome sequencing, disease, gene, variant, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
Monogenic disorder, Cancer PMID:22241780 biotools:kggseq, OMICS_02260 https://bio.tools/kggseq SCR_005311 KGGSeq: A biological Knowledge-based mining platform for Genomic and Genetic studies using Sequence data 2026-08-29 11:22:18 58
Scripture
 
Resource Report
Resource Website
10+ mentions
Scripture (RRID:SCR_005269) Scripture software resource Software for transcriptome reconstruction that relies solely on RNA-Seq reads and an assembled genome to build a transcriptome ab initio. The statistical methods to estimate read coverage significance are also applicable to other sequencing data. Scripture also has modules for ChIP-Seq peak calling. transcriptome, rna-seq read, genome sequence, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
is related to: Alt Event Finder
has parent organization: Broad Institute
PMID:20436462 biotools:scripture, OMICS_01265 https://bio.tools/scripture SCR_005269 2026-08-29 11:22:18 11
becas
 
Resource Report
Resource Website
10+ mentions
becas (RRID:SCR_005337) data access protocol, service resource, software resource, web service Web application, API and widget able to recognize and annotate biomedical concepts in text.Provides annotations for isolated, nested and intersected entities.Identifies concepts from multiple semantic groups, providing preferred names and enriching them with references to public knowledge resources. Annotation, biomedical concept recognition, annotate biomedical concepts, text, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: University of Aveiro; Aveiro; Portugal
Free, Freely available biotools:becas, OMICS_01173 https://bioinformatics.ua.pt/software/becas/, https://bio.tools/becas SCR_005337 2026-08-29 11:22:19 12
NCBO Annotator
 
Resource Report
Resource Website
1+ mentions
NCBO Annotator (RRID:SCR_005329) NCBO Annotator data access protocol, production service resource, service resource, software resource, web service A Web service that annotates textual metadata (e.g. journal abstract) with relevant ontology concepts. NCBO uses this Web service to annotate resources in the NCBO Resource Index. They also provide this Web service as a stand-alone service for users. This Web service can be accessed through BioPortal or used directly in your software. Currently, the annotation workflow is based on syntactic concept recognition (using concept names and synonyms) and on a set of semantic expansion algorithms that leverage the semantics in ontologies (e.g., is_a relations). Their service methodology leverages ontologies to create annotations of raw text and returns them using semantic web standards. ontology, annotation, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
is related to: STOP
has parent organization: BioPortal
has parent organization: National Centers for Biomedical Computing
has parent organization: Stanford University; Stanford; California
NHGRI U54 HG004028 PMID:19483092 biotools:bioportal, nlx_144389, OMICS_01172 https://bio.tools/bioportal SCR_005329 Open Biomedical Annotator, NCBO BioPortal Annotator 2026-08-29 11:22:12 6
CoPub
 
Resource Report
Resource Website
1+ mentions
CoPub (RRID:SCR_005327) CoPub data access protocol, service resource, software resource, web service Text mining tool that detects co-occuring biomedical concepts in abstracts from the MedLine literature database. It allows batch input of multiple human, mouse or rat genes and produces lists of keywords from several biomedical thesauri that are significantly correlated with the set of input genes. These lists link to Medline abstracts in which the co-occurring input genes and correlated keywords are highlighted. Furthermore, CoPub can graphically visualize differentially expressed genes and over-represented keywords in a network, providing detailed insight in the relationships between genes and keywords, and revealing the most influential genes as highly connected hubs. microarray, gene, literature, enrich, annotate, network, database, differential expression, bio.tools uses: MEDLINE
uses: Gene Ontology
is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: Netherlands Bioinformatics Centre
Netherlands Bioinformatics Centre PMID:18442992 Free, Public, Acknowledgement requested OMICS_01178, biotools:copub https://bio.tools/copub http://services.nbic.nl/cgi-bin/copub/CoPub.pl SCR_005327 2026-08-29 11:22:25 5
PeakSeq
 
Resource Report
Resource Website
10+ mentions
PeakSeq (RRID:SCR_005349) PeakSeq software resource A software program for identifying and ranking peak regions in ChIP-Seq experiments. It takes as input, mapped reads from a ChIP-Seq experiment, mapped reads from a control experiment and outputs a file with peak regions ranked with increasing Q-values. bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: Yale University; Connecticut; USA
PMID:19122651 biotools:peakseq, OMICS_00453 https://bio.tools/peakseq SCR_005349 2026-08-29 11:22:13 39
PAZAR
 
Resource Report
Resource Website
10+ mentions
PAZAR (RRID:SCR_005410) PAZAR data or information resource, data repository, database, service resource, software resource, storage service resource Database that unites independently created and maintained data collections of transcription factor and regulatory sequence annotation. The flexible PAZAR schema permits the representation of diverse information derived from experiments ranging from biochemical protein-DNA binding to cellular reporter gene assays. Data collections can be made available to the public, or restricted to specific system users. The data ''boutiques'' within the shopping-mall-inspired system facilitate the analysis of genomics data and the creation of predictive models of gene regulation., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. transcription factor, target gene, regulatory sequence, transcription factor profile, annotation, sequence, profile, transcription factor binding profile, chip, chip-seq, gene, cis-regulatory element, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: University of British Columbia; British Columbia; Canada
has parent organization: SourceForge
PMID:18971253 THIS RESOURCE IS NO LONGER IN SERVICE OMICS_00540, biotools:pazar https://bio.tools/pazar SCR_005410 2026-08-29 11:22:14 32
TIGRFAMS
 
Resource Report
Resource Website
100+ mentions
TIGRFAMS (RRID:SCR_005493) JCVI TIGRFAMS, TIGRFAM data or information resource, data set, database Consists curated multiple sequence alignments, Hidden Markov Models (HMMs) for protein sequence classification, and associated information designed to support automated annotation of (mostly prokaryotic) proteins. Starting with release 10.0, TIGRFAMs models use HMMER3, which provides excellent search speed as well as exquisite search sensitivity. See the "TIGRFAMs Complete Listing" page to review the accession, protein name, model type, and EC number (if assigned) of all models. TIGRFAMs is a member database in InterPro. The HMM libraries and supporting files are available to download and use for free from our FTP site. sequence alignment, hidden markov model, protein sequence, classification, protein, protein family, sequence homology, sequence, homology, function, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
is related to: InterPro
is related to: InterPro
has parent organization: J. Craig Venter Institute
PMID:23197656 Free nif-0000-03560, OMICS_01700, biotools:tigrfams https://bio.tools/tigrfams http://www.tigr.org/TIGRFAMs SCR_005493 TIGRFAMs 2026-08-29 11:22:26 142
Segemehl
 
Resource Report
Resource Website
10+ mentions
Segemehl (RRID:SCR_005494) Segemehl software resource A software to map short sequencer reads to reference genomes. It is able to detect not only mismatches but also insertions and deletions. Furthermore, it is not limited to a specific read length and is able to mapprimer- or polyadenylation contaminated reads correctly. segemehl implements a matching strategy based on enhanced suffix arrays (ESA). Segemehl now supports the SAM format, reads gziped queries to save both disk and memory space and allows bisulfite sequencing mapping and split read mapping. bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
is related to: ANNOgesic
has parent organization: University of Leipzig; Saxony; Germany
PMID:24512684
PMID:22581174
PMID:19750212
DOI:10.1371/journal.pcbi.1000502
Acknowledgement requested, Free, Public biotools:segemehl, OMICS_00683 https://bio.tools/segemehl, https://sources.debian.org/src/segemehl/ SCR_005494 segemehl - short read mapping with gaps 2026-08-29 11:22:21 48
PASS
 
Resource Report
Resource Website
1000+ mentions
PASS (RRID:SCR_005490) PASS software resource THIS RESOURCE IS NO LONGER IN SERVICE. Documented on October 19, 2020.A program to align short sequences that has been developed with an innovative strategy to perform fast gapped and ungapped alignment onto a reference sequence. It supports several data formats and allows the user to modulate very finely the sensitivity of the alignments. The program is designed to handle huge amounts of short reads generated by ILLUMINA, SOLiD and Roche-454 technology. The optimization of the internal data structure and a filter based on precomputed short-word alignments allow the program to skip false positives in the extension phase, thus reducing the execution time without loss of sensitivity. The final alignment is performed by dynamic programming., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
is listed by: SoftCite
is related to: PASS-bis
has parent organization: University of Padua; Padua; Italy
PMID:19218350 THIS RESOURCE IS NO LONGER IN SERVICE biotools:pass, OMICS_00673 https://bio.tools/pass SCR_005490 PASS: a program to align short sequences 2026-08-29 11:22:21 2085

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