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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Specification URL Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
Pavian
 
Resource Report
Resource Website
10+ mentions
Pavian (RRID:SCR_016679) analysis service resource, data analysis service, production service resource, service resource, software resource, web application Software R package for interactive analysis of metagenomics classification results with a special focus on infectious disease diagnosis. Used for analyzing and visualization of metagenomics classification results from classifiers such as Kraken, Centrifuge and MetaPhlAn. Provides an alignment viewer for validation of matches to a particular genome. interactive, analysis, metagenomics, classification, result, infectious, disease, diagnosis, data, visualization, bio.tools is listed by: Debian
is listed by: bio.tools
is related to: Centrifuge Classifier
NHGRI R01 HG006677;
NIGMS R01 GM083873;
U. S. Army Research Office W911NF1410490
DOI:10.1101/084715 Free, Freely available biotools:pavian https://fbreitwieser.shinyapps.io/pavian/, https://bio.tools/pavian SCR_016679 2026-09-05 06:28:12 33
XYalign
 
Resource Report
Resource Website
1+ mentions
XYalign (RRID:SCR_016661) data analysis software, data processing software, sequence analysis software, software application, software resource Software tool for identifying, understanding, and correcting technical biases on the sex chromosomes in next generation sequencing data. correct, technical, bias, sex, chromosome, next, generation, sequencing, data is listed by: OMICtools NIGMS R35 GM124827 DOI:10.1101/346940 Free, Available for download, Freely available SCR_016661 2026-09-05 06:28:12 1
Centrifuge Classifier
 
Resource Report
Resource Website
10+ mentions
Centrifuge Classifier (RRID:SCR_016665) data analysis software, data processing software, sequence analysis software, software application, software resource Software for rapid and sensitive classification of metagenomic sequences. Used for the classification of DNA sequences from microbial samples and analysis of large metagenomics data sets on conventional desktop computers. classification, large, metagenomic, sequence, DNA, microbial, sample, analysis, data, desktop, computer, bio.tools is listed by: bio.tools
is listed by: Debian
is listed by: OMICtools
is related to: Pavian
has parent organization: Center for Computational Biology at JHU
NHGRI R01 HG006677;
NIGMS R01 GM083873;
NSF ABI1356078;
U. S. Army Research Office W911NF1410490
DOI:10.1101/gr.210641.116 Free, Available for download, Freely available biotools:centrifuge, OMICS_12217 https://github.com/infphilo/centrifuge, https://bio.tools/centrifuge, https://sources.debian.org/src/centrifuge/ SCR_016665 2026-09-05 06:28:12 10
KnowEnG
 
Resource Report
Resource Website
1+ mentions
KnowEnG (RRID:SCR_016875) data or information resource, organization portal, portal, software resource, training resource Part of the NIH Big Data to Knowledge (BD2K) Initiative. One of 11 Centers of Excellence in Big Data Computing. Platform for genomics data analysis where user-supplied data sets will be analyzed in the context of existing knowledge. E-science framework for genomics where biomedical scientists will have access to powerful methods of data mining, network mining, and machine learning to extract knowledge out of genomics data. center, excellence, big, data, computing, biomedical, analytics has parent organization: Mayo Clinic
has parent organization: University of Illinois at Urbana-Champaign; Illinois; USA
NIGMS U54 GM114838 PMID:26205246 https://github.com/BD2K/KnowEng SCR_016875 Knowledge Engine for Genomics, The Knowledge Engine for Genomics 2026-09-05 06:28:14 1
Phenograph
 
Resource Report
Resource Website
100+ mentions
Phenograph (RRID:SCR_016919) PhenoGraph data analysis software, data processing software, software application, software resource Software tool as clustering method designed for high dimensional single cell data. Algorithmically defines phenotypes in high dimensional single cell data. Used for large scale analysis of single cell heterogeneity. high, dimention, single, cell, data, phenotype, analysis, heterogeneity uses: Python Programming Language
is related to: Rphenograph
CIRM DR1 01477;
CIRM RB201592;
Entertainment Industry Foundation ;
NCI P01 CA034233;
NCI R01 CA130826;
NCI R01 CA164729;
NCI U54 CA121852;
NCI U54 CA143907;
NCI U54 CA149145;
NIAID U19 AI057229;
NICHD DP1 HD084071;
NIGMS R00 GM104148;
NIH Office of the Director DP2 OD002414;
NIH N01 HV00242;
Packard Fellowship for Science and Engineering ;
Rachford and Carlota Harris Endowed Professorship ;
Stand Up To Cancer Phillip A. Sharp Award SU2CAACRPS04;
US Department of Health and Human Services HHSN272200700038C;
US DOD W81XWH1210591;
US FDA HHSF223201210194C
PMID:26095251 Free, Available for download, Freely available https://github.com/JinmiaoChenLab/Rphenograph https://github.com/jacoblevine/PhenoGraph SCR_016919 2026-09-05 06:28:15 235
CheckMyMetal
 
Resource Report
Resource Website
1+ mentions
CheckMyMetal (RRID:SCR_016887) CMM data access protocol, software resource, web service Metal binding site validation server. Used for systematic inspection of the metal-binding architectures in macromolecular structures. The validation parameters that CMM examines cover the entire binding environment of the metal ion, including the position, charge and type of atoms and residues surrounding the metal. metal, binging, site, validation, server, systematic, inspection, macromolecular, structure, ion, charge, position, atom NHGRI HG008424;
NIAID HHSN272201200026C;
NIGMS GM117325
PMID:28291757 Free, Freely available SCR_016887 2026-09-05 06:28:15 8
BinPacker
 
Resource Report
Resource Website
10+ mentions
BinPacker (RRID:SCR_017038) data analysis software, data processing software, software application, software resource Software tool as de novo trascriptome assembler for RNA-Seq data. Used to assemble full length transcripts by remodeling problem as tracking set of trajectories of items over splicing graph. Input RNA-Seq reads in fasta or fastq format, and ouput all assembled candidate transcripts in fasta format. Operating system Unix/Linux. de novo, transcriptome, assembler, RNAseq, data, full, length, transcript, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
National Natural Science Foundation of China ;
NCRR P20 RR01 6460;
NIGMS P20 GM103429;
NSF 1553680
PMID:26894997 Free, Available for download, Freely available OMICS_11199, biotools:binpacker http://sourceforge.net/projects/transcriptomeassembly/files/BinPacker_1.0.tar.gz/download, http://sourceforge.net/projects/transcriptomeassembly/files/BinPacker_binary.tar.gz/download, https://bio.tools/binpacker SCR_017038 2026-09-05 06:28:17 10
CCPN Data Model
 
Resource Report
Resource Website
CCPN Data Model (RRID:SCR_016982) data or information resource, data processing software, data repository, data storage software, database, service resource, software application, software resource, storage service resource Model to cover data for macromolecular NMR spectroscopy from the initial experimental data to the final validation. Used for the large scale data deposition, data mining and program interoperability. Enables movement from one software package to another without difficulties with data conversion or loss of information. Works with CcpNmr Analysis software for analysis and interactive display, CcpNmr FormatConverter for allowing transfer of data from programs used in NMR to and from the Data Model, and the CLOUDS software for automated structure calculation and assignment. Used within the CCPN software suite for NMR spectroscopy and at the BioMagResBank for converting existing deposited restraint lists to a standard IUPAC nomenclature. data, macromolecular, NMR, spectroscopy, deposition, mining, interoperability, conversion is related to: Biological Magnetic Resonance Data Bank (BMRB)
has parent organization: Collaborative Computing Project for NMR
works with: CCPN Analysis
works with: CCPN Analysis
BBSRC ;
EU ;
NIGMS GM67965;
NLM P41 LM005799
PMID:15815974
PMID:15613391
PMID:21953355
Free, Public SCR_016982 The CCPN Data Model 2026-09-05 06:28:16 0
exRNA Atlas
 
Resource Report
Resource Website
10+ mentions
exRNA Atlas (RRID:SCR_017221) analysis service resource, application programming interface, atlas, consortium, controlled vocabulary, data access protocol, data analysis service, data or information resource, data repository, database, expression atlas, ontology, organization portal, portal, production service resource, service resource, software resource, storage service resource Software tool as data and metadata repository of Extracellular RNA Communication Consortium. Atlas includes small RNA sequencing and qPCR derived exRNA profiles from human and mouse biofluids. All RNAseq datasets are processed using version 4 of exceRpt small RNAseq pipeline. Atlas accepts submissions for RNAseq or qPCR data. Differential, expression, RNA, sequencing, qPCR, data, visualization, extracellular, exRNA, atlas, repository, dataset is recommended by: National Library of Medicine
has parent organization: Baylor College of Medicine; Houston; Texas
has parent organization: exRNA
gastric cancer, colon carcinoma, colorectal cancer, prostate carcinoma, pancreatic carcinoma, multiple sclerosis, glioblastoma multiforme, ulcerative colitis, Alzheimer's disease, ischemic stroke, intraparenchymal hemorrhage of brain, asthma, cardiovascular disorder, myocardial infarction, lupus, nephrotic syndrome, transplanted kidney present, liver disease, transplanted liver present, pre-eclampsia, Parkinson disease, intraventricular brain hemorrhage, subarachnoid hemorrhage American Cancer Society ResearchProfessor Award ;
Frank McGraw Memorial Chair in CancerResearch ;
NCATS UH3 TR000906;
NCATS UH3 TR000943;
NCI CA217685;
NCI R01 CA163849;
NCI R35 CA209904;
NCI U19 CA179512;
NHLBI K23 HL127099;
NHLBI R01 HL122547;
NHLBI R01 HL136685;
NIA R01 AG059729;
NIDA U54 DA036134;
NIDDK P30 DK63720;
NIGMS R25 GM056929
PMID:30951672 Restricted SCR_017221 2026-09-05 06:28:20 29
RNAstructure
 
Resource Report
Resource Website
50+ mentions
RNAstructure (RRID:SCR_017216) analysis service resource, data access protocol, production service resource, service resource, simulation software, software application, software resource, web service Web server for RNA and DNA secondary structure prediction and analysis. Software package as RNA folding prediction program. RNA, DNA, secondary, structure, prediction, analysis is listed by: SoftCite
has parent organization: University of Rochester; New York; USA
NIGMS R01 GM076485 PMID:23620284 Free, Freely available SCR_017216 2026-09-05 06:28:20 58
SerialEM
 
Resource Report
Resource Website
100+ mentions
SerialEM (RRID:SCR_017293) data acquisition software, data processing software, software application, software resource Software tool for automated EM data acquisition. Used for efficient tilt series acquisition and interface for image capture, display, and storage and for control of some aspects of microscope function. automated, data, acquisition, tilt, image, capture, display, storage, microscope NCRR RR00592;
NIGMS P01 GM61306
PMID:16182563 Restricted SCR_017293 2026-09-05 06:28:22 228
Protomo
 
Resource Report
Resource Website
1+ mentions
Protomo (RRID:SCR_017296) data processing software, image processing software, software application, software resource Software tool for electron tomography and 3D image processing. Software package used in electron tomography for marker free alignment and 3D reconstruction of tilt series. Tomography software package distributed for linux operating system and developed by Hanspeter Winkler. electron, tomography, 3D, image, processing NIGMS GM30598;
NIGMS GM64346
PMID:16973379 Restricted SCR_017296 2026-09-05 06:28:22 5
GenePattern Notebook
 
Resource Report
Resource Website
1+ mentions
GenePattern Notebook (RRID:SCR_015699) electronic laboratory notebook, software application, software resource, systems interoperability software, web application Interactive analysis notebook environment that streamlines genomics research by interleaving text, multimedia, and executable code into unified, sharable, reproducible “research narratives.” It integrates the dynamic capabilities of notebook systems with an investigator-focused, simple interface that provides access to hundreds of genomic tools without the need to write code. gene, genomics research, research narrative, notebook system, analysis notebook, bio.tools is listed by: bio.tools
is listed by: Debian
is affiliated with: GenePattern
NIGMS R01-GM074024;
NCI U24-CA194107
PMID:28822753 Open Source, Free, Available for download, Account required biotools:GenePattern_notebook https://bio.tools/GenePattern_notebook SCR_015699 GenePattern Notebook environment 2026-09-05 06:27:58 3
UCSF ChimeraX
 
Resource Report
Resource Website
1000+ mentions
UCSF ChimeraX (RRID:SCR_015872) 3d visualization software, 4d visualization software, data processing software, data visualization software, software application, software resource Software for 3D/4D image reconstruction. UCSF ChimeraX is the next-generation molecular visualization program from the Resource for Biocomputing, Visualization, and Informatics (RBVI), following UCSF Chimera. 3d, 4d, image reconstruction, molecular visualization, biocomputing, informatics, rbvi, ucsf, chimera is related to: UCSF Chimera
is related to: UCSF Chimera
has parent organization: University of California at San Francisco; California; USA
has plug in: ISOLDE
NIGMS P41 GM103311 SCR_015872 ChimeraX 2026-09-05 06:28:00 2366
Brain Imaging Data Structure (BIDs)
 
Resource Report
Resource Website
100+ mentions
Brain Imaging Data Structure (BIDs) (RRID:SCR_016124) BIDS data or information resource, narrative resource, portal, standard specification Standard specification for organizing and describing outputs of neuroimaging experiments. Used to organize and describe neuroimaging and behavioral data by neuroscientific community as standard to organize and share data. BIDS prescribes file naming conventions and folder structure to store data in set of already existing file formats. Provides standardized templates to store associated metadata in form of Javascript Object Notation (JSON) and tab-separated value (TSV) files. Facilitates data sharing, metadata querying, and enables automatic data analysis pipelines. System to curate, aggregate, and annotate neuroimaging databases. Intended for magnetic resonance imaging data, magnetoencephalography data, electroencephalography data, and intracranial encephalography data. Data storing structure, neuroimaging, standardized template, data sharing, MRI data, MEG data, EEG data, iEEG data, FASEB list is used by: OpenNeuro
is used by: SPARC Portal
is used by: SPARC Data Standard
is listed by: FAIRsharing
is related to: BIDS-Matlab
is related to: NiPoppy
works with: MNE-BIDS
European Regional Development Fund ;
German federal state of Sachsen-Anhalt ;
International Neuroinformatics Coordinating Facility ;
Laura and John Arnold Foundation ;
Medical Research Council United Kingdom ;
NIAAA U01 AA021697;
NIGMS P20 GM103472;
NIMH Intramural Research Program ;
NSF 1429999;
Wellcome Trust
PMID:27326542
PMID:29917016
PMID:31239435
PMID:31239438
PMID:37744469
Free, Freely available https://bids-specification.readthedocs.io/en/stable/, https://doi.org/10.25504/FAIRsharing.rd1j6t SCR_016124 Brain Imaging Data Structure, BIDS, Brain Imaging Data Structure (BIDS), Brain Imaging Data Structure v1.4.0 2026-09-05 06:28:04 235
SV-plaudit
 
Resource Report
Resource Website
1+ mentions
SV-plaudit (RRID:SCR_016285) data analysis software, data processing software, image analysis software, software application, software resource Software for rapidly curating structural variant (SVs) predictions. SV-plaudit provides a pipeline for creating image views of genomic intervals, automatically storing them in the cloud, deploying a website to view/score them, and retrieving scores for analysis. genomics, structural, variants, visualization, manual, curation, prediction, image, alignment NCI U24 CA209999;
NHGRI K99 HG009532;
NHGRI R01 HG006693;
NIGMS R01 GM124355
Free, Available for download SCR_016285 2026-09-05 06:28:06 2
star-for-criu
 
Resource Report
Resource Website
1+ mentions
star-for-criu (RRID:SCR_016294) alignment software, data processing software, image analysis software, software application, software resource Software as an Hot Start software container for STAR alignment using CRIU (Checkpoint Restore in Userspace) tool to freeze the running container. Can be deployed to align RNA sequencing data. Used in the processing of biomedical big data for better reproducibility and reliability. hot, start, container, star, aligner, sequencing, data, processing, biomedical, cloud, reproducibility, RNA, analysis, computing, environment is related to: Systems Transcriptional Activity Reconstruction AMEDD Advanced Medical Technology Initiative ;
NHLBI U54 HL127624;
NIGMS R01 GM126019
Free, Freely available, Available for download https://github.com/paizhang/Hotstarting-For-STAR-Alignment SCR_016294 2026-09-05 06:28:06 1
MotionCor2
 
Resource Report
Resource Website
100+ mentions
MotionCor2 (RRID:SCR_016499) data analysis software, data processing software, software application, software resource Software tool for anisotropic correction of beam-induced motion for improved cryo-electron microscopy. Used to describe the sample motion as a local deformation that varies smoothly throughout the exposure. A program running on Linux. anisotropic, correction, beam, induced, motion, cryo, electron, microscopy, exposure, data has parent organization: University of California at San Francisco; California; USA NIGMS P01 GM111126;
NIH R01 GM031627
PMID:28250466 Restricted http://msg.ucsf.edu/em/software/motioncor2.html SCR_016499 MotionCor 2026-09-05 06:28:09 186
HiTIMED
 
Resource Report
Resource Website
HiTIMED (RRID:SCR_028180) software application, software resource, source code Software DNA methylation-based algorithm, to estimate cell proportions in tumor microenvironment. Profiles tumor, immune, and angiogenic components, allowing researchers to study tumor composition and its clinical implications using archival biospecimens. estimate cell proportions, cell type resolution, tumor microenvironment, tumor-type-specific DNA methylation data, NCI P30 CA168524;
NCI P50 CA097257;
NCI R01 CA207360;
NCI R01CA216265;
NIGMS P20 GM130423;
NIGMS P20GM103428;
NIGMS P20GM104416
PMID:36348337 Free, Available for download, Freely available SCR_028180 Hierarchical Tumor Immune Microenvironment Epigenetic Deconvolution 2026-09-05 06:36:07 0
OncoDB
 
Resource Report
Resource Website
50+ mentions
OncoDB (RRID:SCR_028340) data or information resource, database Database offers integrated multi-omic data for patients across 33 cancer types. It encompasses gene expression, DNA methylation, somatic mutations, proteomic profiles, and chromatin accessibility, drawing from TCGA, GTEx, and CPTAC projects. Users can compare gene expression, DNA methylation, and protein levels between tumor and normal tissues, identifying differentially expressed genes and proteins, and examining gene-to-gene correlations. Provides oncogene mutation profiles and allows for survival analysis based on gene expression and methylation, linked to clinical parameters. Facilitates exploration of multi-omic correlations, such as gene expression with DNA methylation, and their variations with mutation status. Extends its analytical capabilities to include six major oncoviruses, offering insights into their impact on gene expression, methylation, and patient survival. cancer patients data, gene expression, DNA methylation, somatic mutations, proteomic profiles, chromatin accessibility, NCI R01CA287778;
NIDCR R01DE026471;
NIGMS R35GM141535
PMID:34718715
PMID:40995640
Free, Freely available, SCR_028340 OncoDB2.0 2026-09-05 06:36:10 84

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