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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
| Resource Name | Proper Citation | Abbreviations | Resource Type |
Description |
Keywords | Resource Relationships | ||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
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University of New England COBRE Histology and Imaging Core Facility Resource Report Resource Website 1+ mentions |
University of New England COBRE Histology and Imaging Core Facility (RRID:SCR_017885) | access service resource, core facility, service resource | Core provides access to expertise, training and specialized instrumentation related to tissue processing, sectioning, staining, immunohistochemistry and microscopy. Offers services and training related to image analysis and image analysis software to guide investigators in choosing best methods for presenting their data.Services include Trimming of wet tissues,Tissue processing into paraffin, OCT and paraffin embedding, Sectioning of paraffin-embedded/frozen tissues, Routine and special histochemical staining, Immunohistochemistry/Immunofluorescence, Antibody optimization, Brightfield/ widefield/ confocal microscopy, Image capture and image analysis.Core has cryostats, microtomes and microscopes available for reservation. | Instrumentation, tissue, processing, sectioning, staining, immunochemistry, microscopy, training, expertise, image, analysis, data, trimming, wet, tissue, processing, paraffin, embedding, immunofluorescence, antibody, optimization, microscopy, cryostat, microtome, service, core | is listed by: ABRF CoreMarketplace | NIGMS P20 GM103643 | Open | ABRF_748 | https://coremarketplace.org/?FacilityID=748&citation=1 | SCR_017885 | SciCrunch Registry | Histology and Imaging Core | 2026-10-17 01:37:43 | 1 | ||||||
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Northwestern University Proteomics Core Facility Resource Report Resource Website 10+ mentions |
Northwestern University Proteomics Core Facility (RRID:SCR_017945) | access service resource, core facility, service resource | Core offers multiple types of experiments from simple protein identification to protein quantitation. Performs traditional bottom-up proteomics, where proteins are digested with enzyme prior to analysis and intact, top-down proteomics analyses. Services include proteins identification after in-gel or in-solution digestion, top-down mass spectrometry to preserve post-translationally modified forms of proteins present in vivo by measuring them intact, IP-MS Pulldown,BioID service to identify target of biotin ligase that has been tagged onto their protein via traditional cloning methods,Untargeted Quantitative Peptide Proteomics,Targeted Quantitative Peptide Proteomics,Epiproteomic Histone Modification Panel A,Epiproteomic Histone Modification Panel B,Untargeted Metabolomics,Phosphoproteomics,PTM Scan,ChIP-MS. | Protein, indentification, quantitation, proteomics, analysis, enzyme, digestion, mass, spectrometry, peptide, targeted, epiproteomic, histone, modification, untargeted, phosphoproteomics, PTM Scan, ChIP-MS, service, core, ABRF |
is listed by: ABRF CoreMarketplace is related to: USEDit has parent organization: Northwestern University; Illinois; USA |
NCI P30 CA060553; NIGMS P41 GM108569; NIH Office of the Director S10 OD025194 |
Open | SCR_017880, ABRF_944 | https://coremarketplace.org/?FacilityID=944 | https://coremarketplace.org/?FacilityID=738 | SCR_017945 | SciCrunch Registry | Northwestern Proteomics, Northwestern University Proteomics Center of Excellence Core Facility | 2026-10-17 01:36:49 | 10 | |||||
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Mount Desert Island Biological Laboratory Light Microscopy Core Facility Resource Report Resource Website 10+ mentions |
Mount Desert Island Biological Laboratory Light Microscopy Core Facility (RRID:SCR_019166) | LMF MDIBL | access service resource, core facility, service resource | Core provides professional scientific expertise in light microscopy. Offers access to hardware and software as well as expert guidance at any step of imaging project, from experimental design to image analysis.Comprises eight microscope systems including two laser scanning confocal microscopes including one Olympus inverted confocal microscope system (FV1000) and one Zeiss inverted confocal microscope system (LSM-980) equipped with Airy scan 2 for super resolution and 2-photon technology for in-vivo deep imaging with temperature controlled chamber. One spinning disk confocal including Nikon inverted spinning disk microscope system with incubation chamber (Eclipse Ti with Yokogawa disk CSU-W1), two Zeiss widefield microscopes for brightfield and epifluorescence illumination (Zeiss Apotome and Zeiss Colibri), three macroscopes systems to observe large samples or complete model organisms in brightfield and epifluorescence including one Olympus stereomicroscope system (MVX10) and two Zeiss stereomicroscope systems (SteREO Discovery V12), fully automated and one AxioZoom V16 , fully automated with ApoTome attachment. | USEDit, light microscopy, imaging project, image analysis, experimental design, ABRF |
is listed by: ABRF CoreMarketplace has parent organization: MDI Biological Laboratory |
NIGMS GM103423 | ABRF_172 | https://coremarketplace.org/?FacilityID=172 | SCR_019166 | SciCrunch Registry | MDIBL Light Microscopy Facility, Light Microscopy Facility MDIBL | 2026-10-17 01:35:59 | 12 | ||||||
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Marshall University School of Medicine Genomics Core Facility Resource Report Resource Website 1+ mentions |
Marshall University School of Medicine Genomics Core Facility (RRID:SCR_018885) | access service resource, core facility, service resource | Core provides services including high throughput next generation sequencing (NGS) to support whole genome, whole exome, RNA-Seq, single cell RNA-Seq, microbiome and global chromatin and methylation studies, biostatistical and bioinformatic support for NGS projects, access to DNA/RNA sequence analysis software, automated Sanger DNA sequencing, genotyping and RNA/DNA quality assessment, access to shared instrumentation such as plate readers, real time thermal cyclers, Agilent Bioanalyzers, fluorimeters, and spectrophotometers. | USEDit, genomics, next generation sequencing, biostatistical and bioinformatic support, RNA-Seq, global chromatin and methylation studies, ABRF |
is listed by: ABRF CoreMarketplace is related to: USEDit has parent organization: Marshall University Joan C. Edwards School of Medicine; West Virginia; USA |
NIGMS 1P20GM121299; NIGMS 2U54GM104942; NIGMS P20GM103434 |
ABRF_163 | https://coremarketplace.org/?FacilityID=163 | SCR_018885 | SciCrunch Registry | Marshall University Genomics Core Facility, MU Genomics Core Facility, Marshall University Genomics and Bioinformatics Core Facilities | 2026-10-17 01:36:52 | 6 | |||||||
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COACH Resource Report Resource Website 1+ mentions |
COACH (RRID:SCR_027684) | data access protocol, software resource, web service | Web application for protein-ligand binding site prediction. Starting from given structure of target proteins, COACH will generate complementray ligand binding site predictions using two comparative methods, TM-SITE and S-SITE, which recognize ligand-binding templates from the BioLiP protein function database by binding-specific substructure and sequence profile comparisons. | protein-ligand binding site prediction, protein, ligand, binding site prediction, | NIGMS GM083107; NIGMS GM084222; NSF Career Award |
PMID:23975762 | Free, Freely available | http://zhanglab.ccmb.med.umich.edu/COACH/ | SCR_027684 | SciCrunch Registry | , COACH server | 2026-10-17 01:38:23 | 7 | |||||||
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RCy3 Resource Report Resource Website 1+ mentions |
RCy3 (RRID:SCR_027668) | software resource, software toolkit, source code | Software R package in Bioconductor that communicates with Cytoscape via its REST API, providing access to the full feature set of Cytoscape from within the R programming environment. RCy3 has been redesigned to streamline its usage and future development as part of a broader Cytoscape Automation effort.Network biology using Cytoscape from within R. | Network biology using Cytoscape from within R, network biology, Cytoscape, R | works with: Cytoscape | Google Summer of Code ; NIGMS P41GM103504 |
PMID:31819800 | Free, Available for download, Freely available | https://bioconductor.org/packages/release/bioc/html/RCy3.html, https://zenodo.org/records/3473421 | SCR_027668 | SciCrunch Registry | RCy3: Network biology using Cytoscape from within R | 2026-10-17 01:38:23 | 9 | ||||||
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CBaSE Resource Report Resource Website |
CBaSE (RRID:SCR_027765) | software application, software resource, source code | Software tool which derives gene-specific probabilistic estimates of the strength of negative and positive selection in cancer. | Cancer Genes, SNV, indel, gene-specific probabilistic estimates, strength of negative and positive selection, cancer | NCI U54 CA143874; NIGMS R01 GM078598; NIMH R01 MH101244 |
PMID:29106416 | Free, Available for download, Freely available | https://github.com/weghornlab/CBaSE, http://genetics.bwh.harvard.edu/cbase | SCR_027765 | SciCrunch Registry | Cancer Bayesian SElection estimation | 2026-10-17 01:39:20 | 0 | |||||||
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CoMUT Resource Report Resource Website 1+ mentions |
CoMUT (RRID:SCR_027745) | software library, software resource, software toolkit, source code | Software Python library for creating comutation plots to visualize genomic and phenotypic information. Used for visualizing genomic and phenotypic information via comutation plots. | genomic DNA, phenotype, visualizing genomic and phenotypic information, comutation plots, | NCI R01 CA227388; NCI R37 CA222574; NCI U01 CA233100; NIGMS T32 GM008313; NSF |
PMID:32502231 | Free, Available for download, Freely available | SCR_027745 | SciCrunch Registry | 2026-10-17 01:38:25 | 4 | |||||||||
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HiTIMED Resource Report Resource Website |
HiTIMED (RRID:SCR_028180) | software application, software resource, source code | Software DNA methylation-based algorithm, to estimate cell proportions in tumor microenvironment. Profiles tumor, immune, and angiogenic components, allowing researchers to study tumor composition and its clinical implications using archival biospecimens. | estimate cell proportions, cell type resolution, tumor microenvironment, tumor-type-specific DNA methylation data, | NCI P30 CA168524; NCI P50 CA097257; NCI R01 CA207360; NCI R01CA216265; NIGMS P20 GM130423; NIGMS P20GM103428; NIGMS P20GM104416 |
PMID:36348337 | Free, Available for download, Freely available | SCR_028180 | SciCrunch Registry | Hierarchical Tumor Immune Microenvironment Epigenetic Deconvolution | 2026-10-17 01:38:35 | 0 | ||||||||
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OncoDB Resource Report Resource Website 50+ mentions |
OncoDB (RRID:SCR_028340) | data or information resource, database | Database offers integrated multi-omic data for patients across 33 cancer types. It encompasses gene expression, DNA methylation, somatic mutations, proteomic profiles, and chromatin accessibility, drawing from TCGA, GTEx, and CPTAC projects. Users can compare gene expression, DNA methylation, and protein levels between tumor and normal tissues, identifying differentially expressed genes and proteins, and examining gene-to-gene correlations. Provides oncogene mutation profiles and allows for survival analysis based on gene expression and methylation, linked to clinical parameters. Facilitates exploration of multi-omic correlations, such as gene expression with DNA methylation, and their variations with mutation status. Extends its analytical capabilities to include six major oncoviruses, offering insights into their impact on gene expression, methylation, and patient survival. | cancer patients data, gene expression, DNA methylation, somatic mutations, proteomic profiles, chromatin accessibility, | NCI R01CA287778; NIDCR R01DE026471; NIGMS R35GM141535 |
PMID:34718715 PMID:40995640 |
Free, Freely available, | SCR_028340 | SciCrunch Registry | OncoDB2.0 | 2026-10-17 01:38:39 | 84 | ||||||||
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MAP Database Guide for Membrane Protein Solubilization Resource Report Resource Website 1+ mentions |
MAP Database Guide for Membrane Protein Solubilization (RRID:SCR_025656) | data or information resource, database | Open access web app that allows users to search for optimal condition for extraction of membrane proteins into membrane active polymers which allows for retention of native membrane environment around target protein. | optimal condition for extraction of membrane proteins, membrane active polymers, retention of native membrane environment, target protein, | has parent organization: Yale University; Connecticut; USA | Michael J. Fox Foundation ; NIGMS R01GM141192; NIGMS R35GM147095; NIGMS RM1GM149406 |
PMID:38405833 | Free, Freely available | SCR_025656 | SciCrunch Registry | Membrane Active Polymers Database Guide for Membrane Protein Solubilization | 2026-10-17 01:37:32 | 1 | |||||||
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SpaGCN Resource Report Resource Website |
SpaGCN (RRID:SCR_025978) | software application, software resource, source code | Software graph convolutional network to integrate gene expression and histology to identify spatial domains and spatially variable genes. SpaGCN integrates information from gene. | Integrating gene expression and histology, graph convolutional network, identify spatial domains, identify spatially variable genes, | NEI R01EY030192; NEI R01EY031209; NHLBI R01HL113147; NHLBI R01HL150359; NIA P01AG066597; NIGMS R01GM125301 |
PMID:34711970 | Free, Available for download, Freely available | SCR_025978 | SciCrunch Registry | 2026-10-17 01:36:56 | 0 | |||||||||
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LinDA Resource Report Resource Website 1+ mentions |
LinDA (RRID:SCR_025966) | data analysis software, data processing software, software application, software resource, source code | Software linear models for differential abundance analysis of microbiome compositional data. Used to tackle compositional effects in differential abundance analysis. It fits linear regression models on centered log2-ratio transformed data, identifies bias term due to transformation and compositional effect, and corrects bias using mode of regression coefficients. It could fit mixed-effect models. | differential abundance analysis, microbiome compositional data, differential abundance analysis, | Mayo Clinic Center for Individualized Medicine ; NIGMS R01GM144351; NSF |
PMID:35421994 | SCR_025966 | SciCrunch Registry | Linear models for differential abundance analysis of microbiome compositional data (LinDA), Linear models for differential abundance analysis of microbiome compositional data | 2026-10-17 01:36:56 | 4 | |||||||||
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Conditional AutoRegressive Deconvolution Resource Report Resource Website 1+ mentions |
Conditional AutoRegressive Deconvolution (RRID:SCR_026310) | CARD | software resource, software toolkit, source code | Software R package for spatial transcriptomics. Deconvolution method that combines cell-type-specific expression information from single-cell RNA sequencing (scRNA-seq) with correlation in cell-type composition across tissue locations. | Deconvolution method, spatial transcriptomics, cell-type-specific expression, single-cell RNA sequencing, cell-type composition across tissue locations, | NHGRI R01HG011883; NIGMS R01GM126553; NIGMS R01GM144960 |
PMID:35501392 | Free, Available for download, Freely available | SCR_026310 | SciCrunch Registry | , CARD: Conditional AutoRegressive Deconvolution, Conditional autoregressive-based deconvolution | 2026-10-17 01:37:07 | 3 | |||||||
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AutoDockTools Resource Report Resource Website 1000+ mentions |
AutoDockTools (RRID:SCR_026401) | ADT | software application, software resource | Software graphical user interface to help to set up which bonds will treated as rotatable in the ligand and to analyze dockings. Used for automated docking with selective receptor flexibility. Designed to predict how small molecules, such as substrates or drug candidates, bind to receptor of known 3D structure. | automated docking, selective receptor flexibility, predict binding, bind to receptor of known 3D structure, ligand, analyze dockings | NIGMS RO1 GM069832 | PMID:19399780 | Free, Available for download, Freely available | https://autodock.scripps.edu/ | SCR_026401 | SciCrunch Registry | AutoDockTools: the Graphical User Interface for AutoDock | 2026-10-17 01:37:10 | 2063 | ||||||
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NucleAIzer Resource Report Resource Website 1+ mentions |
NucleAIzer (RRID:SCR_026500) | software resource, source code | Software tool as parameter-free deep learning framework for nucleus segmentation using image style transfer. Cell segmentation tool. | nucleus segmentation, image style transfer, | Academy of Finland ; European Regional Development Funds ; NIGMS R35 GM122547; Swedish Research Council |
DOI:10.1016/j.cels.2020.04.003 | Free, Available for download, Freely available | SCR_026500 | SciCrunch Registry | 2026-10-17 01:39:03 | 4 | |||||||||
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MeTPeak Resource Report Resource Website 10+ mentions |
MeTPeak (RRID:SCR_026533) | software resource, software toolkit, source code | Software package for finding the location of m6A sites in MeRIP-seq data. | finding location of m6A sites, MeRIP-seq data | Natural Science Foundation of China ; NCI P30CA54174; NCI U54 CA113001; NIGMS R01 GM113245; NSF |
PMID:27307641 | Free, Available for download, Freely available | SCR_026533 | SciCrunch Registry | 2026-10-17 01:37:12 | 11 | |||||||||
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Liftoff Resource Report Resource Website 10+ mentions |
Liftoff (RRID:SCR_026535) | software resource, source code | Software genome annotation lift-over tool capable of mapping genes between two assemblies of the same or closely related species. Aligns genes from reference genome to target genome and finds the mapping that maximizes sequence identity while preserving the structure of each exon, transcript and gene. Used for accurate mapping of gene annotations. | Aligns genes, reference genome to target genome alignment, mapping of gene annotations, genome annotation lift-over, mapping genes between two assemblies of species, mapping genes, same or closely related species, | NHGRI R01 HG006677; NIGMS R35 GM130151 |
PMID:33320174 | Free, Available for download, Freely available | SCR_026535 | SciCrunch Registry | 2026-10-17 01:39:04 | 10 | |||||||||
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EndoMap Resource Report Resource Website 1+ mentions |
EndoMap (RRID:SCR_026690) | data or information resource, database | Structural interactome viewer. Interactive database of endosomal protein-protein interactions identified by cross-linking mass spectrometry and modeled by AlphaFold multimer. Structural protein interactome of human early endosomes. | Structural protein interactome, structural interactome viewer, endosomal protein-protein interactions, human early endosomes, | Aligning Science Across Parkinson ; Michael J Fox Foundation ; NIGMS RO1 GM132129; NINDS R01NS110395 |
DOI:10.1101/2025.02.07.636106 | Free, Freely available | SCR_026690 | SciCrunch Registry | EndoMAP.v1 | 2026-10-17 01:37:55 | 2 | ||||||||
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kraken2 Resource Report Resource Website 1000+ mentions |
kraken2 (RRID:SCR_026838) | software application, software resource, source code | Software tool as second version of Kraken taxonomic sequence classification system. | taxonomic sequence classification system, taxonomic, sequence, classification system, | NIGMS R01 GM118568; NIGMS R35 GM130151; NSF |
PMID:31779668 | Free, Available for download, Freely available | SCR_026838 | SciCrunch Registry | 2026-10-17 01:39:07 | 1421 |
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