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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Specification URL Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Authority Synonyms Record Last Update Mentions Count
University of New England COBRE Histology and Imaging Core Facility
 
Resource Report
Resource Website
1+ mentions
University of New England COBRE Histology and Imaging Core Facility (RRID:SCR_017885) access service resource, core facility, service resource Core provides access to expertise, training and specialized instrumentation related to tissue processing, sectioning, staining, immunohistochemistry and microscopy. Offers services and training related to image analysis and image analysis software to guide investigators in choosing best methods for presenting their data.Services include Trimming of wet tissues,Tissue processing into paraffin, OCT and paraffin embedding, Sectioning of paraffin-embedded/frozen tissues, Routine and special histochemical staining, Immunohistochemistry/Immunofluorescence, Antibody optimization, Brightfield/ widefield/ confocal microscopy, Image capture and image analysis.Core has cryostats, microtomes and microscopes available for reservation. Instrumentation, tissue, processing, sectioning, staining, immunochemistry, microscopy, training, expertise, image, analysis, data, trimming, wet, tissue, processing, paraffin, embedding, immunofluorescence, antibody, optimization, microscopy, cryostat, microtome, service, core is listed by: ABRF CoreMarketplace NIGMS P20 GM103643 Open ABRF_748 https://coremarketplace.org/?FacilityID=748&citation=1 SCR_017885 SciCrunch Registry Histology and Imaging Core 2026-10-17 01:37:43 1
Northwestern University Proteomics Core Facility
 
Resource Report
Resource Website
10+ mentions
Northwestern University Proteomics Core Facility (RRID:SCR_017945) access service resource, core facility, service resource Core offers multiple types of experiments from simple protein identification to protein quantitation. Performs traditional bottom-up proteomics, where proteins are digested with enzyme prior to analysis and intact, top-down proteomics analyses. Services include proteins identification after in-gel or in-solution digestion, top-down mass spectrometry to preserve post-translationally modified forms of proteins present in vivo by measuring them intact, IP-MS Pulldown,BioID service to identify target of biotin ligase that has been tagged onto their protein via traditional cloning methods,Untargeted Quantitative Peptide Proteomics,Targeted Quantitative Peptide Proteomics,Epiproteomic Histone Modification Panel A,Epiproteomic Histone Modification Panel B,Untargeted Metabolomics,Phosphoproteomics,PTM Scan,ChIP-MS. Protein, indentification, quantitation, proteomics, analysis, enzyme, digestion, mass, spectrometry, peptide, targeted, epiproteomic, histone, modification, untargeted, phosphoproteomics, PTM Scan, ChIP-MS, service, core, ABRF is listed by: ABRF CoreMarketplace
is related to: USEDit
has parent organization: Northwestern University; Illinois; USA
NCI P30 CA060553;
NIGMS P41 GM108569;
NIH Office of the Director S10 OD025194
Open SCR_017880, ABRF_944 https://coremarketplace.org/?FacilityID=944 https://coremarketplace.org/?FacilityID=738 SCR_017945 SciCrunch Registry Northwestern Proteomics, Northwestern University Proteomics Center of Excellence Core Facility 2026-10-17 01:36:49 10
Mount Desert Island Biological Laboratory Light Microscopy Core Facility
 
Resource Report
Resource Website
10+ mentions
Mount Desert Island Biological Laboratory Light Microscopy Core Facility (RRID:SCR_019166) LMF MDIBL access service resource, core facility, service resource Core provides professional scientific expertise in light microscopy. Offers access to hardware and software as well as expert guidance at any step of imaging project, from experimental design to image analysis.Comprises eight microscope systems including two laser scanning confocal microscopes including one Olympus inverted confocal microscope system (FV1000) and one Zeiss inverted confocal microscope system (LSM-980) equipped with Airy scan 2 for super resolution and 2-photon technology for in-vivo deep imaging with temperature controlled chamber. One spinning disk confocal including Nikon inverted spinning disk microscope system with incubation chamber (Eclipse Ti with Yokogawa disk CSU-W1), two Zeiss widefield microscopes for brightfield and epifluorescence illumination (Zeiss Apotome and Zeiss Colibri), three macroscopes systems to observe large samples or complete model organisms in brightfield and epifluorescence including one Olympus stereomicroscope system (MVX10) and two Zeiss stereomicroscope systems (SteREO Discovery V12), fully automated and one AxioZoom V16 , fully automated with ApoTome attachment. USEDit, light microscopy, imaging project, image analysis, experimental design, ABRF is listed by: ABRF CoreMarketplace
has parent organization: MDI Biological Laboratory
NIGMS GM103423 ABRF_172 https://coremarketplace.org/?FacilityID=172 SCR_019166 SciCrunch Registry MDIBL Light Microscopy Facility, Light Microscopy Facility MDIBL 2026-10-17 01:35:59 12
Marshall University School of Medicine Genomics Core Facility
 
Resource Report
Resource Website
1+ mentions
Marshall University School of Medicine Genomics Core Facility (RRID:SCR_018885) access service resource, core facility, service resource Core provides services including high throughput next generation sequencing (NGS) to support whole genome, whole exome, RNA-Seq, single cell RNA-Seq, microbiome and global chromatin and methylation studies, biostatistical and bioinformatic support for NGS projects, access to DNA/RNA sequence analysis software, automated Sanger DNA sequencing, genotyping and RNA/DNA quality assessment, access to shared instrumentation such as plate readers, real time thermal cyclers, Agilent Bioanalyzers, fluorimeters, and spectrophotometers. USEDit, genomics, next generation sequencing, biostatistical and bioinformatic support, RNA-Seq, global chromatin and methylation studies, ABRF is listed by: ABRF CoreMarketplace
is related to: USEDit
has parent organization: Marshall University Joan C. Edwards School of Medicine; West Virginia; USA
NIGMS 1P20GM121299;
NIGMS 2U54GM104942;
NIGMS P20GM103434
ABRF_163 https://coremarketplace.org/?FacilityID=163 SCR_018885 SciCrunch Registry Marshall University Genomics Core Facility, MU Genomics Core Facility, Marshall University Genomics and Bioinformatics Core Facilities 2026-10-17 01:36:52 6
COACH
 
Resource Report
Resource Website
1+ mentions
COACH (RRID:SCR_027684) data access protocol, software resource, web service Web application for protein-ligand binding site prediction. Starting from given structure of target proteins, COACH will generate complementray ligand binding site predictions using two comparative methods, TM-SITE and S-SITE, which recognize ligand-binding templates from the BioLiP protein function database by binding-specific substructure and sequence profile comparisons. protein-ligand binding site prediction, protein, ligand, binding site prediction, NIGMS GM083107;
NIGMS GM084222;
NSF Career Award
PMID:23975762 Free, Freely available http://zhanglab.ccmb.med.umich.edu/COACH/ SCR_027684 SciCrunch Registry , COACH server 2026-10-17 01:38:23 7
RCy3
 
Resource Report
Resource Website
1+ mentions
RCy3 (RRID:SCR_027668) software resource, software toolkit, source code Software R package in Bioconductor that communicates with Cytoscape via its REST API, providing access to the full feature set of Cytoscape from within the R programming environment. RCy3 has been redesigned to streamline its usage and future development as part of a broader Cytoscape Automation effort.Network biology using Cytoscape from within R. Network biology using Cytoscape from within R, network biology, Cytoscape, R works with: Cytoscape Google Summer of Code ;
NIGMS P41GM103504
PMID:31819800 Free, Available for download, Freely available https://bioconductor.org/packages/release/bioc/html/RCy3.html, https://zenodo.org/records/3473421 SCR_027668 SciCrunch Registry RCy3: Network biology using Cytoscape from within R 2026-10-17 01:38:23 9
CBaSE
 
Resource Report
Resource Website
CBaSE (RRID:SCR_027765) software application, software resource, source code Software tool which derives gene-specific probabilistic estimates of the strength of negative and positive selection in cancer. Cancer Genes, SNV, indel, gene-specific probabilistic estimates, strength of negative and positive selection, cancer NCI U54 CA143874;
NIGMS R01 GM078598;
NIMH R01 MH101244
PMID:29106416 Free, Available for download, Freely available https://github.com/weghornlab/CBaSE, http://genetics.bwh.harvard.edu/cbase SCR_027765 SciCrunch Registry Cancer Bayesian SElection estimation 2026-10-17 01:39:20 0
CoMUT
 
Resource Report
Resource Website
1+ mentions
CoMUT (RRID:SCR_027745) software library, software resource, software toolkit, source code Software Python library for creating comutation plots to visualize genomic and phenotypic information. Used for visualizing genomic and phenotypic information via comutation plots. genomic DNA, phenotype, visualizing genomic and phenotypic information, comutation plots, NCI R01 CA227388;
NCI R37 CA222574;
NCI U01 CA233100;
NIGMS T32 GM008313;
NSF
PMID:32502231 Free, Available for download, Freely available SCR_027745 SciCrunch Registry 2026-10-17 01:38:25 4
HiTIMED
 
Resource Report
Resource Website
HiTIMED (RRID:SCR_028180) software application, software resource, source code Software DNA methylation-based algorithm, to estimate cell proportions in tumor microenvironment. Profiles tumor, immune, and angiogenic components, allowing researchers to study tumor composition and its clinical implications using archival biospecimens. estimate cell proportions, cell type resolution, tumor microenvironment, tumor-type-specific DNA methylation data, NCI P30 CA168524;
NCI P50 CA097257;
NCI R01 CA207360;
NCI R01CA216265;
NIGMS P20 GM130423;
NIGMS P20GM103428;
NIGMS P20GM104416
PMID:36348337 Free, Available for download, Freely available SCR_028180 SciCrunch Registry Hierarchical Tumor Immune Microenvironment Epigenetic Deconvolution 2026-10-17 01:38:35 0
OncoDB
 
Resource Report
Resource Website
50+ mentions
OncoDB (RRID:SCR_028340) data or information resource, database Database offers integrated multi-omic data for patients across 33 cancer types. It encompasses gene expression, DNA methylation, somatic mutations, proteomic profiles, and chromatin accessibility, drawing from TCGA, GTEx, and CPTAC projects. Users can compare gene expression, DNA methylation, and protein levels between tumor and normal tissues, identifying differentially expressed genes and proteins, and examining gene-to-gene correlations. Provides oncogene mutation profiles and allows for survival analysis based on gene expression and methylation, linked to clinical parameters. Facilitates exploration of multi-omic correlations, such as gene expression with DNA methylation, and their variations with mutation status. Extends its analytical capabilities to include six major oncoviruses, offering insights into their impact on gene expression, methylation, and patient survival. cancer patients data, gene expression, DNA methylation, somatic mutations, proteomic profiles, chromatin accessibility, NCI R01CA287778;
NIDCR R01DE026471;
NIGMS R35GM141535
PMID:34718715
PMID:40995640
Free, Freely available, SCR_028340 SciCrunch Registry OncoDB2.0 2026-10-17 01:38:39 84
MAP Database Guide for Membrane Protein Solubilization
 
Resource Report
Resource Website
1+ mentions
MAP Database Guide for Membrane Protein Solubilization (RRID:SCR_025656) data or information resource, database Open access web app that allows users to search for optimal condition for extraction of membrane proteins into membrane active polymers which allows for retention of native membrane environment around target protein. optimal condition for extraction of membrane proteins, membrane active polymers, retention of native membrane environment, target protein, has parent organization: Yale University; Connecticut; USA Michael J. Fox Foundation ;
NIGMS R01GM141192;
NIGMS R35GM147095;
NIGMS RM1GM149406
PMID:38405833 Free, Freely available SCR_025656 SciCrunch Registry Membrane Active Polymers Database Guide for Membrane Protein Solubilization 2026-10-17 01:37:32 1
SpaGCN
 
Resource Report
Resource Website
SpaGCN (RRID:SCR_025978) software application, software resource, source code Software graph convolutional network to integrate gene expression and histology to identify spatial domains and spatially variable genes. SpaGCN integrates information from gene. Integrating gene expression and histology, graph convolutional network, identify spatial domains, identify spatially variable genes, NEI R01EY030192;
NEI R01EY031209;
NHLBI R01HL113147;
NHLBI R01HL150359;
NIA P01AG066597;
NIGMS R01GM125301
PMID:34711970 Free, Available for download, Freely available SCR_025978 SciCrunch Registry 2026-10-17 01:36:56 0
LinDA
 
Resource Report
Resource Website
1+ mentions
LinDA (RRID:SCR_025966) data analysis software, data processing software, software application, software resource, source code Software linear models for differential abundance analysis of microbiome compositional data. Used to tackle compositional effects in differential abundance analysis. It fits linear regression models on centered log2-ratio transformed data, identifies bias term due to transformation and compositional effect, and corrects bias using mode of regression coefficients. It could fit mixed-effect models. differential abundance analysis, microbiome compositional data, differential abundance analysis, Mayo Clinic Center for Individualized Medicine ;
NIGMS R01GM144351;
NSF
PMID:35421994 SCR_025966 SciCrunch Registry Linear models for differential abundance analysis of microbiome compositional data (LinDA), Linear models for differential abundance analysis of microbiome compositional data 2026-10-17 01:36:56 4
Conditional AutoRegressive Deconvolution
 
Resource Report
Resource Website
1+ mentions
Conditional AutoRegressive Deconvolution (RRID:SCR_026310) CARD software resource, software toolkit, source code Software R package for spatial transcriptomics. Deconvolution method that combines cell-type-specific expression information from single-cell RNA sequencing (scRNA-seq) with correlation in cell-type composition across tissue locations. Deconvolution method, spatial transcriptomics, cell-type-specific expression, single-cell RNA sequencing, cell-type composition across tissue locations, NHGRI R01HG011883;
NIGMS R01GM126553;
NIGMS R01GM144960
PMID:35501392 Free, Available for download, Freely available SCR_026310 SciCrunch Registry , CARD: Conditional AutoRegressive Deconvolution, Conditional autoregressive-based deconvolution 2026-10-17 01:37:07 3
AutoDockTools
 
Resource Report
Resource Website
1000+ mentions
AutoDockTools (RRID:SCR_026401) ADT software application, software resource Software graphical user interface to help to set up which bonds will treated as rotatable in the ligand and to analyze dockings. Used for automated docking with selective receptor flexibility. Designed to predict how small molecules, such as substrates or drug candidates, bind to receptor of known 3D structure. automated docking, selective receptor flexibility, predict binding, bind to receptor of known 3D structure, ligand, analyze dockings NIGMS RO1 GM069832 PMID:19399780 Free, Available for download, Freely available https://autodock.scripps.edu/ SCR_026401 SciCrunch Registry AutoDockTools: the Graphical User Interface for AutoDock 2026-10-17 01:37:10 2063
NucleAIzer
 
Resource Report
Resource Website
1+ mentions
NucleAIzer (RRID:SCR_026500) software resource, source code Software tool as parameter-free deep learning framework for nucleus segmentation using image style transfer. Cell segmentation tool. nucleus segmentation, image style transfer, Academy of Finland ;
European Regional Development Funds ;
NIGMS R35 GM122547;
Swedish Research Council
DOI:10.1016/j.cels.2020.04.003 Free, Available for download, Freely available SCR_026500 SciCrunch Registry 2026-10-17 01:39:03 4
MeTPeak
 
Resource Report
Resource Website
10+ mentions
MeTPeak (RRID:SCR_026533) software resource, software toolkit, source code Software package for finding the location of m6A sites in MeRIP-seq data. finding location of m6A sites, MeRIP-seq data Natural Science Foundation of China ;
NCI P30CA54174;
NCI U54 CA113001;
NIGMS R01 GM113245;
NSF
PMID:27307641 Free, Available for download, Freely available SCR_026533 SciCrunch Registry 2026-10-17 01:37:12 11
Liftoff
 
Resource Report
Resource Website
10+ mentions
Liftoff (RRID:SCR_026535) software resource, source code Software genome annotation lift-over tool capable of mapping genes between two assemblies of the same or closely related species. Aligns genes from reference genome to target genome and finds the mapping that maximizes sequence identity while preserving the structure of each exon, transcript and gene. Used for accurate mapping of gene annotations. Aligns genes, reference genome to target genome alignment, mapping of gene annotations, genome annotation lift-over, mapping genes between two assemblies of species, mapping genes, same or closely related species, NHGRI R01 HG006677;
NIGMS R35 GM130151
PMID:33320174 Free, Available for download, Freely available SCR_026535 SciCrunch Registry 2026-10-17 01:39:04 10
EndoMap
 
Resource Report
Resource Website
1+ mentions
EndoMap (RRID:SCR_026690) data or information resource, database Structural interactome viewer. Interactive database of endosomal protein-protein interactions identified by cross-linking mass spectrometry and modeled by AlphaFold multimer. Structural protein interactome of human early endosomes. Structural protein interactome, structural interactome viewer, endosomal protein-protein interactions, human early endosomes, Aligning Science Across Parkinson ;
Michael J Fox Foundation ;
NIGMS RO1 GM132129;
NINDS R01NS110395
DOI:10.1101/2025.02.07.636106 Free, Freely available SCR_026690 SciCrunch Registry EndoMAP.v1 2026-10-17 01:37:55 2
kraken2
 
Resource Report
Resource Website
1000+ mentions
kraken2 (RRID:SCR_026838) software application, software resource, source code Software tool as second version of Kraken taxonomic sequence classification system. taxonomic sequence classification system, taxonomic, sequence, classification system, NIGMS R01 GM118568;
NIGMS R35 GM130151;
NSF
PMID:31779668 Free, Available for download, Freely available SCR_026838 SciCrunch Registry 2026-10-17 01:39:07 1421

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