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URL: http://kt.ijs.si/software/SEGS/
Proper Citation: SEGS (RRID:SCR_003554)
Description: A web tool for descriptive analysis of microarray data. The analysis is performed by looking for descriptions of gene sets that are statistically significantly over- or under-expressed between different scenarios within the context of a genome-scale experiments (DNA microarray). Descriptions are defined by using the terms from the Gene Ontology (GO), the Kyoto Encyclopedia of Genes and Genomes (KEGG) pathways and gene-gene interactions found in the ENTREZ database. Gene annotations by GO and KEGG terms can also be found in the ENTREZ database. The tool provides three procedures for testing the enrichment of the gene sets (over- or under-expressed): Fisher's exact test, GSEA and PAGE, and option for combining the results of the tests. Because of the multiple-hypothesis testing nature of the problem, all the p-values are computed using the permutation testing method.
Abbreviations: SEGS
Synonyms: Search for Enriched Gene Sets
Resource Type: analysis service resource, data analysis service, production service resource, service resource
Defining Citation: PMID:18234563
Keywords: microarray, pathway, gene-gene interaction, gene, interaction, annotation, gene expression, ortholog, molecular function, biological process, cellular component, enriched gene set, gene set
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