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Plasmid Name
pSicoR-shS6K1/2
RRID:Addgene_81088 RRID Copied  
PDF Report How to cite
RRID:Addgene_81088
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Plasmid Information

URL: http://www.addgene.org/81088

Proper Citation: RRID:Addgene_81088

Insert Name: S6K1 & S6K2 shRNA

Organism: Mus musculus

Bacterial Resistance: Ampicillin

Defining Citation: PMID:24139800

Vector Backbone Description: Backbone Marker:Jacks Lab (MIT); Backbone Size:7567; Vector Backbone:pSicoR; Vector Types:Mammalian Expression, Lentiviral, RNAi, Cre/Lox; Bacterial Resistance:Ampicillin

Comments: pSicoR allows for expression of the S6K1/2 shRNA in the absence of Cre. Expression of Cre turns off shRNA expression. These plasmids were also used in the following publication "Normalizing translation through 4E-BP prevents mTOR-driven cortical mislamination and ameliorates aberrant neuron integration. Lin TV, Hsieh L, Kimura T, Malone TJ, Bordey A. Proc Natl Acad Sci U S A. 2016 Oct 4;113(40):11330-11335."

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Data and Source Information

Source: Addgene