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Plasmid Name
pLHCX-XBP1 mNeonGreen NLS
RRID:Addgene_115971 RRID Copied  
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RRID:Addgene_115971
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Plasmid Information

URL: http://www.addgene.org/115971

Proper Citation: RRID:Addgene_115971

Insert Name: X-box binding protein 1

Organism: Homo sapiens

Bacterial Resistance: Ampicillin

Defining Citation: PMID:30088945

Vector Backbone Description: Backbone Marker:Clontech; Backbone Size:6813; Vector Backbone:pLHCX; Vector Types:Mammalian Expression, Retroviral; Bacterial Resistance:Ampicillin

Comments: This sensor leads to the expression of a mNeonGreen fusion protein in the nucleus upon induction of ER-stress. ER-stress kinetic through the IRE1/XBP1 pathway can thus be monitored by recording the green fluorescent signal arising in the nucleus. Designed by Adrien Nougarède.

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Data and Source Information

Source: Addgene