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URL: http://www.addgene.org/42511
Proper Citation: RRID:Addgene_42511
Insert Name: Pyruvate Kinase M1
Organism: Mus musculus
Bacterial Resistance: Ampicillin
Defining Citation: PMID:22052977
Vector Backbone Description: Backbone Marker:Clontech; Backbone Size:6800; Vector Backbone:pLHCX; Vector Types:Retroviral; Bacterial Resistance:Ampicillin
Comments: Plasmid constructed by Heather Christofk in Lew Cantley's Lab. Ref: Christofk, H. R., Vander Heiden, M. G., Harris, M. H., Ramanathan, A., Gerszten, R. E., Wei, R., Fleming, M. D., et al. (2008). The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth. Nature, 452(7184), 230–233. doi:10.1038/nature06734 The depositing scientist notes: NM_011099.3 is PKM2 and NM_001253883.1 is PKM1, based on sequence homology of the respective translated products to the human PKM isoforms. The isoform annotations in the corresponding GeneBank entries are incorrect.
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Source: Addgene
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