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URL: http://www.addgene.org/225490
Proper Citation: RRID:Addgene_225490
Insert Name: Potassium channel subfamily K member 2
Organism: Mus musculus
Bacterial Resistance: Ampicillin
Defining Citation: PMID:39029456
Vector Backbone Description: Vector Backbone:pcDNA3.1; Vector Types:Mammalian Expression, Neuronal expression; Bacterial Resistance:Ampicillin
Comments: NOTE: Also known as TREK-1CG* A286F and used in chemogenetic strategy termed CATKLAMP (covalent activation of TREK family K+ channels to clamp membrane potential) for irreversibly activating K2P potassium channels and thereby silencing of electrical activity in neurons in the presence of CAT335, a maleimide derivative of the K2P modulator pocket activator ML335.
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No rating or validation information has been found for pCDNA3.1(+)-hSyn-HA-mTREK-1(S131C/A286F)-IRES-GFP.
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Source: Addgene
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