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URL: http://toppgene.cchmc.org/
Proper Citation: ToppGene Suite (RRID:SCR_005726)
Description: ToppGene Suite is a one-stop portal for gene list enrichment analysis and candidate gene prioritization based on functional annotations and protein interactions network. ToppGene Suite is a one-stop portal for (i) gene list functional enrichment, (ii) candidate gene prioritization using either functional annotations or network analysis and (iii) identification and prioritization of novel disease candidate genes in the interactome. Functional annotation-based disease candidate gene prioritization uses a fuzzy-based similarity measure to compute the similarity between any two genes based on semantic annotations. The similarity scores from individual features are combined into an overall score using statistical meta-analysis.
Synonyms: ToppGene
Resource Type: analysis service resource, data analysis service, data or information resource, database, portal, production service resource, resource, service resource
Defining Citation: PMID:19465376
Keywords: gene portal, enrichment analysis, functional annotation, gene prioritization, protein interaction, bio.tools, FASEB list
Funding: State of Ohio Computational Medicine Center ODD TECH 04-042; NIDDK 1U01DK70219; NIDDK P30DK078392
Availability: Free for academic use
Resource Name: ToppGene Suite
Resource ID: SCR_005726
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Source: SciCrunch Registry (RRID:SCR_005400)
Description: Interactive portal for finding and submitting biomedical resources. Resources within SciCrunch have assigned RRIDs which are used to cite resources in scientific manuscripts. SciCrunch Registry, formerly NIF Registry, provides resources catalog. Allows to add new resources. Allows edit existing resources after registration. Curators are tasked with identifying and registering resources, examining data, writing configuration files to index and display data and keeping contents current.
URL: https://rrid.site/rin/sources/SCR_005400
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