NIF Data Spotlight: GEO

Gene Expression Omnibus (GEO) is an another database of NCBI that holds gene expression information. It international public repository that archives and freely distributes microarray, next-generation sequencing, and other forms of high-throughput functional genomics data submitted by the research community. It provides robust and versatile database of gene expression profiles that provides an opportunity for scientists to easily submit their research and query for others' works.

NIF's federated search engine provides variety of information from GEO, including GEO Accession, experiment description, experiment type, organism, platform, technology and contributor. Any of these categories can be used to search related expression profiles in GEO. For example, if we wanted to look up some data on human's snp variation. We can search for "human snp variation" and navigate to Data Type > Microarray > GEO:GEO, and browse for any gene expression profile of interest (shown below).



Clicking on the GEO accession number will direct the users to the more detailed page in GEO. The page will show you more detailed description of the experiment and its results. They also have downloadable files that users can download.

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The NIF Data Spotlight is a weekly blog post highlighting the databases, information, and resources curated by the Neuroscience Information Framework. For comments, questions or concerns feel free to drop us a line at curation@neuinfo.org.