Representing Neurons
- 12:56pm January 22, 2010
- NIF Blogger
How does NIF represent neurons, the basic unit of information processing in the brain?
Each class organized by NIF is a concatenation of a brain region and known cell type. Cell type is determined by any distinguishing features and common practice. Thus, the substantia nigra pars compacta dopamine neuron is a class of a cell that has been morphologically and physiologically characterized and identified by its neurochemical signature. There is a probable relation to the VTA DA cells but as we are not certain, we add the brain region to distinguish between the two classes. NIF has automatically generated inferred classes such as "Dopaminergic neuron" which is any neuron that uses dopamine as a neurotransmitter. However, that is not a primary class. NIF is also adding "Substantia nigra neuron" as an inferred class, which is any neuron whose soma lies in any part of the substantia nigra. We are grouping these under the Neurolex "Inferred neuron class" to distinguish them from the primary asserted neuron types.