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 PMID:33737344  

Copy number loss in granzyme genes confers resistance to immune checkpoint inhibitor in nasopharyngeal carcinoma.

Yuxiang Ma | Xi Chen | Ao Wang | Hongyun Zhao | Qingguang Lin | Hua Bao | Yang Zhang | Shaodong Hong | Wanxiangfu Tang | Yan Huang | Yunpeng Yang | Xue Wu | Yang Shao | Wenfeng Fang | Li Zhang
Journal for immunotherapy of cancer | 2021

Anti-programmed death (PD)-1 therapy has recently been used in recurrent or metastatic (R/M) nasopharyngeal carcinoma (NPC). The long-term survival and its biomarkers responding to anti-PD-1 treatment in patients with R/M NPC remain unclear.

Pubmed ID: 33737344

Research resources used in this publication

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Additional research tools detected in this publication

Antibodies used in this publication

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This is a list of tools and resources that we have found mentioned in this publication.


Picard (tool)

RRID:SCR_006525

Java toolset for working with next generation sequencing data in the BAM format.

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Trimmomatic (tool)

RRID:SCR_011848

Software Java pipeline for trimming tasks for Illumina paired end and single ended data. Flexible Trimmer for Illumina Sequence Data. Pair aware preprocessing tool optimized for Illumina next generation sequencing data. Includes several processing steps for read trimming and filtering. Operating systems Unix/Linux, Mac OS, Windows.

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Scalpel (tool)

RRID:SCR_012107

A software package for detecting INDELs (INsertions and DELetions) mutations in a reference genome which has been sequenced with next-generation sequencing technology (e.g., Illumina).

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