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 PMID:33402096  

D-mannose ameliorates autoimmune phenotypes in mouse models of lupus.

Haiting Wang | Xiangyu Teng | Georges Abboud | Wei Li | Shuang Ye | Laurence Morel
BMC immunology | 2021

Systemic lupus erythematosus is an autoimmune disease characterized by an overproduction of autoantibodies resulting from dysregulation in multiple immune cell types. D-mannose is a C- 2 epimer of glucose that exhibits immunoregulatory effects in models of autoimmune diseases, such as type 1 diabetes, induced rheumatoid arthritis, and airway inflammation. This study was conducted to evaluate the efficacy of D-mannose treatment in mouse models of lupus.

Pubmed ID: 33402096

Research resources used in this publication

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Associated grants

  • Agency: NIAID NIH HHS, United States
    Id: R01 AI128901

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Promega (tool)

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