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 PMID:31260875  

Stimulation of alpha 7 nicotinic acetylcholine receptor (α7nAChR) inhibits atherosclerosis via immunomodulatory effects on myeloid cells.

Marcus A Ulleryd | Filip Mjörnstedt | Dimitra Panagaki | Li Jin Yang | Kajsa Engevall | Saray Gutiérrez | Yixin Wang | Li-Ming Gan | Holger Nilsson | Erik Michaëlsson | Maria E Johansson
Atherosclerosis | 2019

Alpha 7 nicotinic acetylcholine receptor (α7nAChR) stimulation can regulate acute inflammation, and lack of α7nAChR accelerates atherosclerosis in mice. In this study, we aimed to investigate the effects of the novel α7nAChR agonist, AZ6983, on atherosclerosis and assess its possible immunomodulating effects.

Pubmed ID: 31260875

Research resources used in this publication

None found

Antibodies used in this publication

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Associated grants

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BD FACSDiva Software (tool)

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