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 PMID:31130472  

In-depth characterization of congenital Zika syndrome in immunocompetent mice: Antibody-dependent enhancement and an antiviral peptide therapy.

Vidyleison N Camargos | Giselle Foureaux | Daniel C Medeiros | Vivian T da Silveira | Celso M Queiroz-Junior | Ana Luisa B Matosinhos | André F A Figueiredo | Carla D F Sousa | Thaiane P Moreira | Victória F Queiroz | Ana Carolina F Dias | Karina T O Santana | Ingredy Passos | Ana Luíza C V Real | Ludmila C Silva | Flávio A G Mourão | Natália T Wnuk | Milton A P Oliveira | Soraia Macari | Tarcília Silva | Gustavo P Garlet | Joshua A Jackman | Frederico M Soriani | Márcio F D Moraes | Eduardo M A M Mendes | Fabíola M Ribeiro | Guilherme M J Costa | Antônio L Teixeira | Nam-Joon Cho | Antônio C P Oliveira | Mauro M Teixeira | Vivian V Costa | Danielle G Souza
EBioMedicine | 2019

Zika virus (ZIKV) infection during pregnancy may cause major congenital defects, including microcephaly, ocular, articular and muscle abnormalities, which are collectively defined as Congenital Zika Syndrome. Here, we performed an in-depth characterization of the effects of congenital ZIKV infection (CZI) in immunocompetent mice.

Pubmed ID: 31130472

Research resources used in this publication

None found

Antibodies used in this publication

None found

Associated grants

None

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ATCC (tool)

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Global nonprofit biological resource center (BRC) and research organization that provides biological products, technical services and educational programs to private industry, government and academic organizations. Its mission is to acquire, authenticate, preserve, develop and distribute biological materials, information, technology, intellectual property and standards for the advancement and application of scientific knowledge. The primary purpose of ATCC is to use its resources and experience as a BRC to become the world leader in standard biological reference materials management, intellectual property resource management and translational research as applied to biomaterial development, standardization and certification. ATCC characterizes cell lines, bacteria, viruses, fungi and protozoa, as well as develops and evaluates assays and techniques for validating research resources and preserving and distributing biological materials to the public and private sector research communities.

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