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 PMID:29860496  

Development of Clinical-Stage Human Monoclonal Antibodies That Treat Advanced Ebola Virus Disease in Nonhuman Primates.

Kristen E Pascal | Drew Dudgeon | John C Trefry | Manu Anantpadma | Yasuteru Sakurai | Charles D Murin | Hannah L Turner | Jeanette Fairhurst | Marcela Torres | Ashique Rafique | Ying Yan | Ashok Badithe | Kevin Yu | Terra Potocky | Sandra L Bixler | Taylor B Chance | William D Pratt | Franco D Rossi | Joshua D Shamblin | Suzanne E Wollen | Justine M Zelko | Ricardo Carrion | Gabriella Worwa | Hilary M Staples | Darya Burakov | Robert Babb | Gang Chen | Joel Martin | Tammy T Huang | Karl Erlandson | Melissa S Willis | Kimberly Armstrong | Thomas M Dreier | Andrew B Ward | Robert A Davey | Margaret L M Pitt | Leah Lipsich | Peter Mason | William Olson | Neil Stahl | Christos A Kyratsous
The Journal of infectious diseases | 2018

For most classes of drugs, rapid development of therapeutics to treat emerging infections is challenged by the timelines needed to identify compounds with the desired efficacy, safety, and pharmacokinetic profiles. Fully human monoclonal antibodies (mAbs) provide an attractive method to overcome many of these hurdles to rapidly produce therapeutics for emerging diseases.

Pubmed ID: 29860496

Associated grants

  • Agency: NIH HHS, United States
    Id: P51 OD011133

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Sino Biological (tool)

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Texas Biomedical Research Institute; Texas; USA (tool)

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An independent biomedical research institution specializing in genetics and in virology and immunology. Texas Biomed is funded by government and corporate grants and contracts, and donations from the public. (Wikipedia)

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