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PMID:29860395

The Orphan Receptor GPR35 Contributes to Angiotensin II-Induced Hypertension and Cardiac Dysfunction in Mice.

Nina Divorty | Graeme Milligan | Delyth Graham | Stuart A Nicklin

American journal of hypertension | 2018

The orphan receptor G protein-coupled receptor 35 (GPR35) has been associated with a range of diseases, including cancer, inflammatory bowel disease, diabetes, hypertension, and heart failure. To assess the potential for GPR35 as a therapeutic target in cardiovascular disease, this study investigated the cardiovascular phenotype of a GPR35 knockout mouse under both basal conditions and following pathophysiological stimulation.

Pubmed ID: 29860395

Research resources used in this publication

None found

Additional research tools detected in this publication

C57BL/6J (RRID:IMSR_JAX:000664)

Antibodies used in this publication

None found

Associated grants

Agency: Wellcome Trust, United Kingdom
Agency: Wellcome Trust, United Kingdom
Id: 099787/Z/12/Z
Agency: British Heart Foundation, United Kingdom
Id: RE/13/5/30177

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C57BL/6J (tool)

RRID:IMSR_JAX:000664

Mus musculus with name C57BL/6J from IMSR.

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