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Prostate cancer (PCa) is one of the most common malignant diseases among male patients. Although androgen deprivation therapy remains the main treatment for PCa, most patients would inevitably progress to castration-resistant PCa, which is the main cause of cancer-related deaths. Thus, novel antitumor agents are urgently needed. Recent studies demonstrated that aloperine (ALO) as a natural alkaloid showed antitumor effects in other cancer types. However, the biological function and underlying mechanisms of ALO in PCa have not been investigated.
Pubmed ID: 29785122
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View all literature mentionsCell line DU145 is a Cancer cell line with a species of origin Homo sapiens (Human)
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View all literature mentionsCell line LNCaP is a Cancer cell line with a species of origin Homo sapiens (Human)
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