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PMID:29679791

Phosphorodiamidate morpholino targeting the 5' untranslated region of the ZIKV RNA inhibits virus replication.

Waldemar Popik | Atanu Khatua | James E K Hildreth | Benjamin Lee | Donald J Alcendor

Virology | 2018

Zika virus (ZIKV) infection has been associated with microcephaly in infants. Currently there is no treatment or vaccine. Here we explore the use of a morpholino oligonucleotide targeted to the 5' untranslated region (5'-UTR) of the ZIKV RNA to prevent ZIKV replication.

Pubmed ID: 29679791

Research resources used in this publication

None found

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Santa Cruz Biotechnology (RRID:SCR_008987)

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Associated grants

Agency: NIDDK NIH HHS, United States
Id: R21 DK094735
Agency: NIDDK NIH HHS, United States
Id: R21 DK089980
Agency: NIMHD NIH HHS, United States
Id: U54 MD007586
Agency: NCRR NIH HHS, United States
Id: U54 RR019192
Agency: NIGMS NIH HHS, United States
Id: R25 GM059994

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