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 PMID:29544490  

The acute diuretic effect of an ethanolic fraction of Phyllanthus amarus (Euphorbiaceae) in rats involves prostaglandins.

Alain N'guessan Yao | Mamadou Kamagaté | Augustin Kouao Amonkan | Philippe Chabert | Fidèle Kpahé | Camille Koffi | Mathieu N'goran Kouamé | Cyril Auger | Séraphin Kati-Coulibaly | Valérie Schini-Kerth | Henri Die-Kakou
BMC complementary and alternative medicine | 2018

Phyllanthus amarus (Schum & Thonn), a plant belonging to the family of Euphorbiaceae is used in Ivorian traditional medicine to treat cardiovascular disorders such as hypertension. However, although this plant has been described as a diuretic agent, the underlying mechanism remains unclear. Therefore, the aim of the present study was to investigate the mechanism action of diuretic effects of an ethanolic fraction of Phyllanthus amarus (EFPA) in rats.

Pubmed ID: 29544490

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Associated grants

  • Agency: Sercice de Coopération et d'Action Culturelle of French Embassy of Côte d'Ivoire,
    Id: Campus France N° 767294B and 796998H
  • Agency: Ministère de l'Enseignement Supérieur et de la Recherche Scientifique of Côte d'Ivoire,
    Id: Décision N° 436 du 11/09/2013

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WI (tool)

RRID:RGD_13508588

Rattus norvegicus with name WI from RGD.

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