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 PMID:28114589  

Murine Corneal Inflammation and Nerve Damage After Infection With HSV-1 Are Promoted by HVEM and Ameliorated by Immune-Modifying Nanoparticle Therapy.

Rebecca G Edwards | Sarah J Kopp | Igal Ifergan | Jr-Wen Shui | Mitchell Kronenberg | Stephen D Miller | Richard Longnecker
Investigative ophthalmology & visual science | 2017

To determine cellular and temporal expression patterns of herpes virus entry mediator (HVEM, Tnfrsf14) in the murine cornea during the course of herpes simplex virus 1 (HSV-1) infection, the impact of this expression on pathogenesis, and whether alterations in HVEM or downstream HVEM-mediated effects ameliorate corneal disease.

Pubmed ID: 28114589

Research resources used in this publication

None found

Antibodies used in this publication

None found

Associated grants

  • Agency: NINDS NIH HHS, United States
    Id: R01 NS026543
  • Agency: NIAID NIH HHS, United States
    Id: R01 AI061516
  • Agency: NIAID NIH HHS, United States
    Id: U01 AI125955
  • Agency: NCI NIH HHS, United States
    Id: P30 CA060553
  • Agency: NIGMS NIH HHS, United States
    Id: T32 GM008152
  • Agency: NEI NIH HHS, United States
    Id: R01 EY023977
  • Agency: NEI NIH HHS, United States
    Id: T32 EY025202

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BioLegend (tool)

RRID:SCR_001134

Commercial antibody supplier and developer for biomedical research. These products are compatible with use in flow cytometry and mass cytometry, immunoprecipitation and chip, western blotting, immunofluorescence microscopy, and quantitative multiplexing.

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Thermo Fisher Scientific (tool)

RRID:SCR_008452

Commercial vendor and service provider of laboratory reagents and antibodies. Supplier of scientific instrumentation, reagents and consumables, and software services.

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FlowJo (tool)

RRID:SCR_008520

Software for single-cell flow cytometry analysis. Its functions include management, display, manipulation, analysis and publication of the data stream produced by flow and mass cytometers.

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Vero (tool)

RRID:CVCL_0059

Cell line Vero is a Spontaneously immortalized cell line with a species of origin Chlorocebus sabaeus

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BALB/cAnNCrl (tool)

RRID:MGI:2683685

laboratory mouse with name BALB/cAnNCrl from MGI.

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C57BL/6J (tool)

RRID:IMSR_JAX:000664

Mus musculus with name C57BL/6J from IMSR.

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