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Integrated Animals is a virtual database currently indexing available animal strains and mutants from: AGSC (Ambystoma), BCBC (mice), BDSC (flies), European Xenopus Resource Center (frog), The National Xenopus Resource (frog), Xenopus Express (frog), CWRU Cystic Fibrosis Mouse Models (mice), DGGR (flies), FlyBase (flies), IMSR (mice), MGI (mice), MMRRC (mice), NSRRC (pig), RGD (rats), Sperm Stem Cell Libraries for Biological Research (rats), Tetrahymena Stock Center (Tetrahymena), WormBase (worms), XGSC (Xiphophorus), ZFIN (zebrafish), and ZIRC (zebrafish). Note, the IMSR data is linked, but users may need to re-execute the search if the top mouse is not returned properly.
Note: BCBC is no longer in service, so the links may not be functional.
http://www.wormbase.org/db/get?name=WBStrain00004531
Source Database: WormBase (WB)
Affected Genes: WBGene00001609(glp-1)
Genomic Alteration: WBGene00001609(glp-1)
Availability: available
Source References: PMID:31576668, PMID:32049015, PMID:33034119, PMID:34610328, PMID:37118502, PMID:37474586, PMID:37624117, PMID:37644339, PMID:37722055, PMID:37729202, PMID:38177158, PMID:38740431, PMID:38816072, PMID:38869949, PMID:38908368, PMID:39164296
Synonyms: glp-1(e2141)
Alternate IDs: WB-STRAIN:CB4037, CGC_CB4037
Notes: Made_by: Schnabels|"Reference WBPaper00059294 added based on published strain data identified by Textpresso literature search."|"Supplementary_genotype glp-1(e2141) III."|"Supplementary_genotype [glp-1(e2141)]"|"Temperature sensitive. Sterile at 25C. Maintain at 15C. Do not distribute this strain; other labs should request it from the CGC. This strain cannot be distributed to commercial organizations. This strain cannot be used for any commercial purpose or for work on human subjects. [2/98: Craig Mello noticed a different embryonic phenotype in this strain as compared to the e2141 stock that Jim Priess obtained from England-the ABp fate appears WT.] [NOTE (11/16/10 - J. Hubbard): This strain is NOT synonymous with glp-1(e2144) as previously reported in Kodoyianni V, Maine EM, Kimble J. (1992) [Molecular basis of loss-of-function mutations in the glp-1 gene of Caenorhabditis elegans. Mol Biol Cell. 3,1199-213. PMID: 1457827]. As reported in Worm Breeders Gazette December 2010; 18(3), e2144 carries the mutation c2785t in exon 8, leading to the amino acid change L929F, whereas e2141 carries the mutations c2920t and a3610g in exon 8, leading to the amino acid changes R974C and T1204A.]"|"WBStrain provided so WBPaper00060426 paper added based on AFP_Strain data."|"WBStrain provided so WBPaper00060484 paper added based on AFP_Strain data."|"WBStrain provided so WBPaper00061436 paper added based on AFP_Strain data."
Proper citation: RRID:WB-STRAIN:WBStrain00004531 Copy
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