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Integrated Animals is a virtual database currently indexing available animal strains and mutants from: AGSC (Ambystoma), BCBC (mice), BDSC (flies), European Xenopus Resource Center (frog), The National Xenopus Resource (frog), Xenopus Express (frog), CWRU Cystic Fibrosis Mouse Models (mice), DGGR (flies), FlyBase (flies), IMSR (mice), MGI (mice), MMRRC (mice), NSRRC (pig), RGD (rats), Sperm Stem Cell Libraries for Biological Research (rats), Tetrahymena Stock Center (Tetrahymena), WormBase (worms), XGSC (Xiphophorus), ZFIN (zebrafish), and ZIRC (zebrafish). Note, the IMSR data is linked, but users may need to re-execute the search if the top mouse is not returned properly.
Note: BCBC is no longer in service, so the links may not be functional.
| Organism Name | Proper Citation | Species | Synonyms |
Notes |
Phenotype | Affected Gene | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
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LE-Adora2aem1(iCre)Berke Resource Report Resource Website 1+ mentions |
RRID:RRRC_00857 | Rattus norvegicus | The CRISPR system was used to created target insertion of iCre recombinase immediately after Adora2a gene, with P2A linker, of the embryos of BluHsd:LE. Rat Resource and Research Center | 00857 | mutant | Rat Resource and Research Center (RRRC) | RRRC | Live Animals (as of 2021-02-12) | RGD_14398734, 14398734, RRRC_857, RRRC_0857, RRRC_00857 | 2026-08-29 02:55:00 | 6 | |||||
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SD-Tg(TRE-TARDBP-M337V) Resource Report Resource Website 1+ mentions |
RRID:RRRC_00633 | Rattus norvegicus | Strain carries a transgene expressing human TDP43 with the M337V mutation under control of a tTA-dependent promoter (TRE). When mated to a second transgenic strain (RRRC:632) that carries a tetracycline-controlled transactivator driven by the mouse choline acetyltransferase (Chat) promoter, the expression of mutant TDP43 in Chat-expressing motor neurons in the double transgenic rats can be induced by withdrawal of doxycycline. Rat Resource and Research Center | 00633 | transgenic | Rat Resource and Research Center (RRRC) | RRRC | Cryopreserved Sperm (as of 2019-02-05) | RGD_7245494, 7245494, RRRC_633, RRRC_0633, RRRC_00633 | 2026-08-29 02:54:59 | 2 | |||||
|
SD-Tg(Chat-tTA) Resource Report Resource Website 1+ mentions |
RRID:RRRC_00632 | Rattus norvegicus | Rats express a mouse tetracycline-controlled transactivator (tTA) driven by the mouse choline acetyltransferase (Chat) promotor. When mated to a second transgenic strain (RRRC:00633) that carries a target gene (TDP43) under the regulation of a tetracycline response element (TRE), the expression of TDP43 in Chat-expressing motor neurons in the double transgenic rats can be induced by withdrawal of doxycycline. Rat Resource and Research Center | 00632 | transgenic | Rat Resource and Research Center (RRRC) | RRRC | Cryopreserved Sperm (as of 2019-02-05) | RGD_7245488, 7245488, RRRC_632, RRRC_0632, RRRC_00632 | 2026-08-29 02:55:00 | 2 | |||||
|
MR/NRrrc Maudsely reactive Resource Report Resource Website 1+ mentions |
RRID:RRRC_00173 | Rattus norvegicus | Origin: as for MNR except selection was for high defecation response in the open field. To Harrington in 1965 at F25 and to NIH in 1964 at F18+ (Hansen et al 1982). Now is available at Rat Resource & Research Center Rat Resource and Research Center, RGD HRDP, contact HRDP | 00173 | inbred | Rat Resource and Research Center (RRRC) | RRRC | Live Animals; Cryopreserved Embryo; Cryorecovery (as of 2023-10-25) | RGD_153323320, 153323320, RRRC_00173 | 2026-08-29 02:55:02 | 1 | |||||
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F344-Tg(CAG-ACE2)057BrydRrrc Resource Report Resource Website 1+ mentions |
RRID:RRRC_00946 | Rattus norvegicus | The human ACE2 gene was placed under control of the synthetic CAG promoter which allows ubiquitous expression of the gene. Based on droplet digital PCR analysis, the strain carries only 1 copy of the transgene. The integration site is unknown. These rats express the human ACE2 gene. The encoded protein is a functional receptor for the spike glycoprotein of several human coronaviruses including SARS-CoV-2, the causative agent of coronavirus disease-2019 (COVID-19). Rat Resource and Research Center | 00946 | transgenic | Rat Resource and Research Center (RRRC) | RRRC | Live Animals (as of 2022-11-04) | RGD_155641251, 155641251, RRRC_946, RRRC_0946, RRRC_00946 | 2026-08-29 02:55:00 | 1 | |||||
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LE-Tg(cFos-eGFP)2Ottc Resource Report Resource Website 1+ mentions |
RRID:RRRC_00766 | Rattus norvegicus | The transgene contains reporter rat expressing eGFP in cFos expressing cells Optogenetics and Transgenic Technology Core, Rat Resource and Research Center | 00766 | transgenic | Rat Resource and Research Center (RRRC) | RRRC | Unknown | RGD_9588570, 9588570, RRRC_766, RRRC_0766, RRRC_00766 | 2026-08-29 02:55:01 | 1 | |||||
|
LE-Tg(Slc6a3-icre)1Ottc Resource Report Resource Website 1+ mentions |
RRID:RRRC_00730 | Rattus norvegicus | The transgene contains BAC transgenic using rat DAT promoter to express Cre recombinase in dopaminergic neurons Optogenetics and Transgenic Technology Core, Rat Resource and Research Center | 00730 | transgenic | Rat Resource and Research Center (RRRC) | RRRC | Unknown | RGD_9588572, 9588572, RRRC_730, RRRC_0730, RRRC_00730 | 2026-08-29 02:55:04 | 2 | |||||
|
SD-Tg(Oprm1-icre)1Ottc Resource Report Resource Website 1+ mentions |
RRID:RRRC_00975 | Rattus norvegicus | Targeted knock-in adding a T2A-iCre to the Oprm1 (mu opioid receptor) in this cre recombinase reporter SD rat Rat Resource and Research Center | 00975 | transgenic | Rat Resource and Research Center (RRRC) | RRRC | Live Animals; Cryopreserved Embryo; Cryopreserved Sperm (as of 2023-12-13) | RGD_155641245, 155641245, RRRC_975, RRRC_0975, RRRC_00975 | 2026-08-29 02:55:02 | 1 | |||||
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SD-Tg(Rho*S334X)4Lav Resource Report Resource Website 1+ mentions |
RRID:RRRC_00645 | Rattus norvegicus | This transgenic strain carries a mouse rhodopsin gene that bears a termination codon at residue 334, which encodes a C-terminal truncated opsin protein. Retinal Degeneration Rat Model Resource ,Rat Resource and Research Center | 00645 | transgenic | Rat Resource and Research Center (RRRC) | RRRC | Unknown | RGD_1358303, 1358303, RRRC_645, RRRC_0645, RRRC_00645 | 2026-08-29 02:55:01 | 1 | |||||
|
SD-Tg(Rho*P23H)3Lav Resource Report Resource Website 1+ mentions |
RRID:RRRC_00641 | Rattus norvegicus | This transgenic strain carries a copy of mouse Rhodopsin gene with a proline to histidine substitution at codon 23 (c.68C>A). Retinal Degeneration Rat Model Resource ,Rat Resource and Research Center | 00641 | transgenic | Rat Resource and Research Center (RRRC) | RRRC | Unknown | RGD_1358300, 1358300, RRRC_641, RRRC_0641, RRRC_00641 | 2026-08-29 02:55:01 | 1 | |||||
|
SD-Chrna6em2Slot Resource Report Resource Website 1+ mentions |
RRID:RRRC_00985 | Rattus norvegicus | Using CRISPR/Cas9 genomic engineering in rats via homologous end-joining in fertilized embryos, we have knocked'in a humanized CHRNA6 3'UTR in place of the natural CHRNA6 3'UTR of the Sprague Dawley rat line. This new genetically modified CHRNA6C123G humanized rat line carries a homozygous CC nucleotide modification at position 123 within the CHRNA6 gene 3'UTR. The laboratory has deposited these strains with the Rat Resource and Research Center | 00985 | mutant | Rat Resource and Research Center (RRRC) | RRRC | Unknown (as of 2023-12-19) | RGD_155900757, 155900757, RRRC_985, RRRC_0985, RRRC_00985 | 2026-08-29 02:55:00 | 1 | |||||
|
N:SD Sprague-Dawley Resource Report Resource Website 10+ mentions |
RRID:RRRC_00239 | Rattus norvegicus | To N 1945 from Sprague Dawley, Inc. Colony closed since then. NIH Autoimmune Rat Model Repository and Development Center, Rat Resource and Research Center | 00239 | outbred | Rat Resource and Research Center (RRRC) | RRRC | Extinct | RGD_728193, 728193, RRRC_239, RRRC_0239, RRRC_00239 | 2026-08-29 02:55:03 | 21 | |||||
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LE-ROSA26 em1(CAG-Cas9)Ottc Resource Report Resource Website 1+ mentions |
RRID:RRRC_00833 | Rattus norvegicus | The CRISPR/Case9 knock-in rats have cre recombinase-dependent expression of Cas9 under the control of CAG promoter inserted to the rat ROSA26 locus. ROSA26 is a synonym for rat Thumpd3-as1 (RGD:6491660) and is used as an official symbol for rat strain nomenclature. Rat Resource and Research Center | 00833 | mutant | Rat Resource and Research Center (RRRC) | RRRC | Cryorecovery (as of 2025-08-29) | RGD_13208224, 13208224, RRRC_833, RRRC_0833, RRRC_00833 | 2026-08-29 02:55:02 | 2 | |||||
|
F344-Tp53tm1(EGFP-Pac)Qly/Rrrc Resource Report Resource Website 1+ mentions |
RRID:RRRC_00661 | Rattus norvegicus | Backcrossed STOCK-Tp53tm1(EGFP-Pac)QlyRrrc with F344 using speed congenic approach to move mutation onto F344 genetic background. Rat Resource and Research Center | 00661 | mutant | Rat Resource and Research Center (RRRC) | RRRC | Unknown | RGD_7364940, 7364940, RRRC_661, RRRC_0661, RRRC_00661 | 2026-08-29 02:55:01 | 1 | |||||
|
SS-Cd40em1Uthal-/- Resource Report Resource Website 1+ mentions |
RRID:RRRC_00840 | Rattus norvegicus | Zinc Finger Nuclease (ZFN) was utilized to knockout rat CD40 function in the embryos of SS/JrHsd rats. The target sequence (CAGCACCGACACTGCgaactcAGTGCGTGGGGCTGCCGGG) introduced an 11 bp-deletion (CTGCGAACTCA) in the third exon of the Cd40 gene, resulted in a trucated protein. Rat Resource and Research Center | 00840 | mutant | Rat Resource and Research Center (RRRC) | RRRC | Unknown | RGD_14398460, 14398460, RRRC_840, RRRC_0840, RRRC_00840 | 2026-08-29 02:55:02 | 1 | |||||
|
LE-Fxn em2Fara-/+/Rrrc Resource Report Resource Website 1+ mentions |
RRID:RRRC_00961 | Rattus norvegicus | Heterozygous KO of the Fxn gene obtained by targeting exon 4 with CRISPR/Cas9 system Rat Resource and Research Center | 00961 | mutant | Rat Resource and Research Center (RRRC) | RRRC | Unknown | RGD_152999002, 152999002, RRRC_961, RRRC_0961, RRRC_00961 | 2026-08-29 02:55:05 | 1 | |||||
|
LE-Tg(DIO-mCherry)2Ottc Resource Report Resource Website 1+ mentions |
RRID:RRRC_00687 | Rattus norvegicus | The transgene contains Cre recombinase reporter rat expressing mCherry driven by the EF1 alpha promoter. A Rrrc substrain available at Rat Resource and Research Center | 00687 | transgenic | Rat Resource and Research Center (RRRC) | RRRC | Unknown | RGD_150521660, 150521660, RRRC_687, RRRC_0687, RRRC_00687 | 2026-08-29 02:55:02 | 3 | |||||
|
LH.LH-Chr 17LN-(Fanccrgdv551196202-C-rs107291522)/Aek Resource Report Resource Website 1+ mentions |
RRID:RRRC_00825 | Rattus norvegicus | This congenic strain contains a fragment of chromosome 17 from the LH-Chr 17LN/Aek from Fanccrgdv551196202-C through rs107291522 transferred to the LH/MRrrcAek background. Rat Resource & Research Center | 00825 | congenic | Rat Resource and Research Center (RRRC) | RRRC | Unknown | RGD_13207341, 13207341, RRRC_825, RRRC_0825, RRRC_00825 | 2026-08-29 02:55:02 | 1 | |||||
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SD-Lrp5em2Vari/Rrrc Resource Report Resource Website 1+ mentions |
RRID:RRRC_00880 | Rattus norvegicus | CRISPR/Cas9 system was used to introduce a 22-bp deletion at the sgRNA2 site of exon 2 in the rat Lrp5 gene of Crl:SD embryos. Rat Resource and Research Center | 00880 | mutant | Rat Resource and Research Center (RRRC) | RRRC | Unknown | RGD_150521606, 150521606, RRRC_880, RRRC_0880, RRRC_00880 | 2026-08-29 02:55:05 | 1 | |||||
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SD-Il15em1Soar Resource Report Resource Website 1+ mentions |
RRID:RRRC_00769 | Rattus norvegicus | Zinc finger nuclease mediated 7bp deletion within exon 2 of the Il15 gene, resulting in a frameshift and premature stop codon. Rat Resource and Research Center | 00769 | mutant | Rat Resource and Research Center (RRRC) | RRRC | Unknown | RGD_11087551, 11087551, RRRC_769, RRRC_0769, RRRC_00769 | 2026-08-29 02:55:01 | 2 |
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