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Integrated Animals is a virtual database currently indexing available animal strains and mutants from: AGSC (Ambystoma), BCBC (mice), BDSC (flies), European Xenopus Resource Center (frog), The National Xenopus Resource (frog), Xenopus Express (frog), CWRU Cystic Fibrosis Mouse Models (mice), DGGR (flies), FlyBase (flies), IMSR (mice), MGI (mice), MMRRC (mice), NSRRC (pig), RGD (rats), Sperm Stem Cell Libraries for Biological Research (rats), Tetrahymena Stock Center (Tetrahymena), WormBase (worms), XGSC (Xiphophorus), ZFIN (zebrafish), and ZIRC (zebrafish). Note, the IMSR data is linked, but users may need to re-execute the search if the top mouse is not returned properly.
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  • Genomic Alteration:wbgene00006843(unc-119) (facet)

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Organism Name Proper Citation Species Synonyms Notes Phenotype Affected Gene Genomic Alteration Catalog Number Background Database Database Abbreviation Availability Source References Alternate IDs Authority Record Last Update Mentions Count
FT1450
 
Resource Report
Resource Website
RRID:WB-STRAIN:WBStrain00007550 Caenorhabditis elegans unc-119(ed3) III; xnIs23; xnEx342. xnIs23 [cdc-42p::ZF1::GFP::cdc-42 + unc-119(+)]. xnEx342 [rab-3p::zif-1 + rab-3p::mCherry + rol-6(su1006)]. Pick Rollers to maintain. ZF1::GFP::cdc-42 is expressed ubiquitously and enriched at the plasma membrane. In embryos inheriting xnEx342, ZF1::GFP::cdc-42 is degraded and mCherry is expressed in neurons. Reference: Armenti ST, et al. Development. 2014 Dec;141(23):4640-7. WBGene00006843(unc-119) WBGene00006843(unc-119) WB-STRAIN:WBStrain00007550 WormBase (WB) WB available WB-STRAIN:FT1450, CGC_FT1450 WormBase 2026-10-24 10:59:26 0
FT1394
 
Resource Report
Resource Website
RRID:WB-STRAIN:WBStrain00007549 Caenorhabditis elegans unc-119(ed3) III; xnIs502. xnIs502 [pie-1p::GFP::jac-1 + unc-119(+)]. Maintain at 25C to slow silencing of transgene. GFP::JAC-1 localized at contacts in early embryos. Reference: Klompstra D, et al. Nat Cell Biol. 2015 Jun;17(6):726-35. WBGene00006843(unc-119) WBGene00006843(unc-119) WB-STRAIN:WBStrain00007549 WormBase (WB) WB available WB-STRAIN:FT1394, CGC_FT1394 WormBase 2026-10-24 10:59:26 0
FT1379
 
Resource Report
Resource Website
RRID:WB-STRAIN:WBStrain00007548 Caenorhabditis elegans avr-14(ad1302) I; xnSi34 II; unc-119 (ed3) III; glc-1(pk54::Tc1) avr-15(ad1051) V. xnSi34 [sec-15::YFP + unc-119(+)] II. Expresses sec-15::YFP maternally and zygotically. Expression is present in many cells, including early embryos, epithelial cells, the excretory cell, and the germ line. Transgene was inserted by MosSCI into ttTi5605 excision site. Derived from WM186. Reference: Armenti ST, Chan E, Nance J. Dev Biol. 2014 Aug 4. pii: S0012-1606(14)00355-8. WBGene00000232(avr-14)|WBGene00000233(avr-15)|WBGene00001591(glc-1)|WBGene00006843(unc-119) WBGene00000232(avr-14), WBGene00000233(avr-15), WBGene00001591(glc-1), WBGene00006843(unc-119) WB-STRAIN:WBStrain00007548 WormBase (WB) WB available WB-STRAIN:FT1379, CGC_FT1379 WormBase 2026-10-24 10:59:26 0
FT1569
 
Resource Report
Resource Website
RRID:WB-STRAIN:WBStrain00007556 Caenorhabditis elegans unc-119(ed3) III; xnIs371; xnEx385. xnIs371 [pie-1p::GFP::pac-1(1-574) + unc-119(+)]. xnEx385 [hsp16p::HA::phplc1(delta)1::hmr-1(ICD-M) + rol-6(su1006)]. Rollers. Rollers express mutated HMR-1 intracellular domain (unable to bind catenins) pan-cortically in cells upon heat shock. Maintain at 15C or 20C to prevent leaky expression of heat shock transgene. Reference: Klompstra D, et al. Nat Cell Biol. 2015 Jun;17(6):726-35. WBGene00006843(unc-119) WBGene00006843(unc-119) WB-STRAIN:WBStrain00007556 WormBase (WB) WB available WB-STRAIN:FT1569, CGC_FT1569 WormBase 2026-10-24 10:59:26 0
GA906
 
Resource Report
Resource Website
RRID:WB-STRAIN:WBStrain00007686 Caenorhabditis elegans unc-119(ed3) III; pkIs1641. pkIs1641 [unc-119(+)]. Derived by outcrossing NL3908 to HT1593 (six times). Reference: Burnett C, et al. Nature. 2011 Sep 21;477(7365):482-5.|"Reference WBPaper00058832 added based on published strain data identified by Textpresso literature search." WBGene00006843(unc-119) WBGene00006843(unc-119) WB-STRAIN:WBStrain00007686 WormBase (WB) WB available PMID:21839827
PMID:31704915
WB-STRAIN:GA906, CGC_GA906 WormBase 2026-10-24 10:59:28 0
GC822
 
Resource Report
Resource Website
RRID:WB-STRAIN:WBStrain00007717 Caenorhabditis elegans unc-119(ed3) III; naEx75. Made_by: R. Voutev/J. Hubbard|"naEx75 [(pGC146) hsp-16.2p::FLP::let-858 3'UTR) + Cbr-unc-119(+) + (pCW2.1) ceh-22p::GFP)]. Array was bombarded but did not integrate." WBGene00006843(unc-119) WBGene00006843(unc-119) WB-STRAIN:WBStrain00007717 WormBase (WB) WB available WB-STRAIN:GC822, CGC_GC822 WormBase 2026-10-24 10:59:29 0
GC817
 
Resource Report
Resource Website
RRID:WB-STRAIN:WBStrain00007716 Caenorhabditis elegans unc-119(ed3) III; naIs6. Made_by: R. Voutev/J. Hubbard|"naIs6 [hsp-16.2p::FLP::let-858 3'UTR + Cbr-unc-119(+) + ceh-22p::GFP)]." WBGene00006843(unc-119) WBGene00006843(unc-119) WB-STRAIN:WBStrain00007716 WormBase (WB) WB available WB-STRAIN:GC817, CGC_GC817 WormBase 2026-10-24 10:59:29 0
GC773
 
Resource Report
Resource Website
RRID:WB-STRAIN:WBStrain00007714 Caenorhabditis elegans unc-119(ed3) III; naIs3. Made_by: R. Voutev/J. Hubbard|"naIs3 [(pGC133) hsp-16.41::FLP:::let-858 3'UTR) + Cbr-unc-119(+)]." WBGene00006843(unc-119) WBGene00006843(unc-119) WB-STRAIN:WBStrain00007714 WormBase (WB) WB available WB-STRAIN:GC773, CGC_GC773 WormBase 2026-10-24 10:59:29 0
GR1719
 
Resource Report
Resource Website
RRID:WB-STRAIN:WBStrain00007944 Caenorhabditis elegans unc-119(ed3) III; mgSi3 IV. Made_by: Tai Montgomery|"mgSi3 [(pCMP2)ubl-1p::GFP::ubl-1-3'UTR + Cbr-unc-119(+)] IV. Strong ubiquitous GFP expression. Can be used as a control for a strain containing an endogenous siRNA sensor (GR1720). Reference: Montgomery TA, et al. PLoS Genet. 2012;8(4):e1002616." WBGene00006843(unc-119) WBGene00006843(unc-119) WB-STRAIN:WBStrain00007944 WormBase (WB) WB available WB-STRAIN:GR1719, CGC_GR1719 WormBase 2026-10-24 10:59:32 0
GRU102
 
Resource Report
Resource Website
1+ mentions
RRID:WB-STRAIN:WBStrain00007980 Caenorhabditis elegans gnaIs2 [myo-2p::YFP + unc-119p::Abeta1-42] gnaIs2 [myo-2p::YFP + unc-119p::Abeta1-42]. Pan-neuronal amyloid beta1-42 expression. Impaired neuromuscular and sensorimotor behavior. See GRU101 for wild-type control strain. Reference: Fong S, et al. Sci Rep. 2016 Sep 22;6:33781. doi: 10.1038/srep33781.|"Supplementary_genotype gnaIs2 [myo-2p::YFP + unc-119p::Abeta1-42],"|[2020-10-08T19:09:27.569Z WBPerson324] Ressurect Strain: Genotype: gnaIs2 [myo-2p::YFP + unc-119p::humanAbeta1-42]|[2020-10-08T23:35:51.358Z WBPerson324] Ressurect Strain: Genotype: gnaIs2 [myo-2p::YFP + unc-119p::Abeta1-42] WBGene00003514(myo-2)|WBGene00006843(unc-119) WBGene00003514(myo-2), WBGene00006843(unc-119) WB-STRAIN:WBStrain00007980 WormBase (WB) WB available PMID:32088829
PMID:37080524
PMID:37838776
PMID:39149885
PMID:39329779
WB-STRAIN:GRU102, CGC_GRU102 WormBase 2026-10-24 10:59:33 5
HCC21
 
Resource Report
Resource Website
RRID:WB-STRAIN:WBStrain00008383 Caenorhabditis elegans hwSi3 II; unc-119(ed9) III. hwSi3 [pie-1p::GFP::mex-3::pie-1 3'UTR + unc-119(+)] II. Worms are healthiest at 15C. Shift to 25C overnight to increase brightness of GFP. Mos1-mediated single-copy insertion (MosSCI) into EG4322. GFP-tagged transgene expressing full-length MEX-3 uniformly throughout oocytes and early embryos through the 4-cell stage. GFP::MEX-3 then mirrors endogenous MEX-3, disappearing from somatic cells by about the 12-cell stage. Also detected in P granules. GFP::MEX-3 can replace endogenous MEX-3. Reference: Huang NN & Hunter CP. Gene. 2015 Jan 10;554(2):160-73. WBGene00006843(unc-119) WBGene00006843(unc-119) WB-STRAIN:WBStrain00008383 WormBase (WB) WB available WB-STRAIN:HCC21, CGC_HCC21 WormBase 2026-10-24 10:59:38 0
HCL67
 
Resource Report
Resource Website
RRID:WB-STRAIN:WBStrain00008386 Caenorhabditis elegans unc-119(ed3) III; uocIs1. uocIs1 [eft-3p::Cas9(dpiRNA)::tbb-2 3' UTR + unc-119(+)]. Cas9 is optimized to remove all piRNA sites. Cas9 is expressed in the germline. Reference: Zhang D, et al. Science. 2018 Feb 2;359(6375):587-592. WBGene00006843(unc-119) WBGene00006843(unc-119) WB-STRAIN:WBStrain00008386 WormBase (WB) WB available PMID:33440146
PMID:37453426
WB-STRAIN:HCL67, CGC_HCL67 WormBase 2026-10-24 10:59:38 0
HBR986
 
Resource Report
Resource Website
RRID:WB-STRAIN:WBStrain00008316 Caenorhabditis elegans unc-119(ed3) III; goeEx361. goeEx361 [ceh-24p::ReaChr::mKate2::unc-54 3'UTR + unc-119(+)]. Pick non-Unc to maintain. Reporter expresses ReaChr with expression control mKate2. Reference: Schwarz J & Bringmann H. eLife 2017;10.7554/eLife.24846. WBGene00006843(unc-119) WBGene00006843(unc-119) WB-STRAIN:WBStrain00008316 WormBase (WB) WB available WB-STRAIN:HBR986, CGC_HBR986 WormBase 2026-10-24 10:59:37 0
HT1708
 
Resource Report
Resource Website
RRID:WB-STRAIN:WBStrain00008523 Caenorhabditis elegans unc-119(ed3) III; wwEx68. Made_by: Walhout/Tissenbaum|"wwEx68 [ins-9p::GFP + unc-119(+)]. Pick wild-type (non-Unc) to maintain. Reference: Ritter AD, et al. Genome Res. 2013 Mar 28." WBGene00006843(unc-119) WBGene00006843(unc-119) WB-STRAIN:WBStrain00008523 WormBase (WB) WB available WB-STRAIN:HT1708, CGC_HT1708 WormBase 2026-10-24 10:59:40 0
HT1711
 
Resource Report
Resource Website
RRID:WB-STRAIN:WBStrain00008524 Caenorhabditis elegans unc-119(ed3) III; wwEx69. Made_by: Walhout/Tissenbaum|"wwEx69 [ins-10p::GFP + unc-119(+)]. Pick wild-type (non-Unc) to maintain. Reference: Ritter AD, et al. Genome Res. 2013 Mar 28." WBGene00006843(unc-119) WBGene00006843(unc-119) WB-STRAIN:WBStrain00008524 WormBase (WB) WB available WB-STRAIN:HT1711, CGC_HT1711 WormBase 2026-10-24 10:59:40 0
HT1714
 
Resource Report
Resource Website
RRID:WB-STRAIN:WBStrain00008525 Caenorhabditis elegans unc-119(ed3) III; wwEx70. Made_by: Walhout/Tissenbaum|"wwEx70 [ins-11p::GFP + unc-119(+)]. Pick wild-type (non-Unc) to maintain. Reference: Ritter AD, et al. Genome Res. 2013 Mar 28." WBGene00006843(unc-119) WBGene00006843(unc-119) WB-STRAIN:WBStrain00008525 WormBase (WB) WB available WB-STRAIN:HT1714, CGC_HT1714 WormBase 2026-10-24 10:59:40 0
HT1718
 
Resource Report
Resource Website
RRID:WB-STRAIN:WBStrain00008526 Caenorhabditis elegans unc-119(ed3) III; wwIs27. Made_by: Walhout/Tissenbaum|"wwIs27 [ins-12p::GFP + unc-119(+)]. Pick wild-type (non-Unc) to maintain. Reference: Ritter AD, et al. Genome Res. 2013 Mar 28." WBGene00006843(unc-119) WBGene00006843(unc-119) WB-STRAIN:WBStrain00008526 WormBase (WB) WB available WB-STRAIN:HT1718, CGC_HT1718 WormBase 2026-10-24 10:59:40 0
HT1737
 
Resource Report
Resource Website
RRID:WB-STRAIN:WBStrain00008532 Caenorhabditis elegans unc-119(ed3) III; wwEx74. Made_by: Walhout/Tissenbaum|"wwEx74 [ins-18p::GFP + unc-119(+)]. Pick wild-type (non-Unc) to maintain. Reference: Ritter AD, et al. Genome Res. 2013 Mar 28." WBGene00006843(unc-119) WBGene00006843(unc-119) WB-STRAIN:WBStrain00008532 WormBase (WB) WB available WB-STRAIN:HT1737, CGC_HT1737 WormBase 2026-10-24 10:59:40 0
HT1803
 
Resource Report
Resource Website
RRID:WB-STRAIN:WBStrain00008548 Caenorhabditis elegans unc-119(ed3) III; wwIs40. Made_by: Walhout/Tissenbaum|"wwIs40 [ins-37p::GFP + unc-119(+)]. Pick wild-type (non-Unc) to maintain. Reference: Ritter AD, et al. Genome Res. 2013 Mar 28." WBGene00006843(unc-119) WBGene00006843(unc-119) WB-STRAIN:WBStrain00008548 WormBase (WB) WB available WB-STRAIN:HT1803, CGC_HT1803 WormBase 2026-10-24 10:59:40 0
HT1806
 
Resource Report
Resource Website
RRID:WB-STRAIN:WBStrain00008549 Caenorhabditis elegans unc-119(ed3) III; wwEx83. Made_by: Walhout/Tissenbaum|"wwEx83 [ins-38p::GFP + unc-119(+)]. Pick wild-type (non-Unc) to maintain. Reference: Ritter AD, et al. Genome Res. 2013 Mar 28." WBGene00006843(unc-119) WBGene00006843(unc-119) WB-STRAIN:WBStrain00008549 WormBase (WB) WB available WB-STRAIN:HT1806, CGC_HT1806 WormBase 2026-10-24 10:59:40 0

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