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Integrated Animals is a virtual database currently indexing available animal strains and mutants from: AGSC (Ambystoma), BCBC (mice), BDSC (flies), European Xenopus Resource Center (frog), The National Xenopus Resource (frog), Xenopus Express (frog), CWRU Cystic Fibrosis Mouse Models (mice), DGGR (flies), FlyBase (flies), IMSR (mice), MGI (mice), MMRRC (mice), NSRRC (pig), RGD (rats), Sperm Stem Cell Libraries for Biological Research (rats), Tetrahymena Stock Center (Tetrahymena), WormBase (worms), XGSC (Xiphophorus), ZFIN (zebrafish), and ZIRC (zebrafish). Note, the IMSR data is linked, but users may need to re-execute the search if the top mouse is not returned properly.
Note: BCBC is no longer in service, so the links may not be functional.
http://www.wormbase.org/db/get?name=WBStrain00062720
Source Database: WormBase (WB)
Affected Genes: WBGene00006977(zif-1)|WBGene00044431(mzt-1)
Genomic Alteration: WBGene00006977(zif-1), WBGene00044431(mzt-1)
Availability: unknown
Source References: EMPTY
Synonyms: mzt-1(wow51[GFP::3xFLAG::mzt-1]) I; zif-1(gk117) III.
Notes: GFP and 3xFLAG tags inserted into endogenous mzt-1 locus. No overt phenotypes. GFP fluorescence is observed at microtubule-organizing centers. Reference: Sallee M, et al. PLoS Biol. 2018 Aug 6;16(8):e2005189. doi: 10.1371/journal.pbio.2005189. PMID: 30080857.|"Made_by: Jenny Zonka"
Proper citation: RRID:WB-STRAIN:WBStrain00062720 Copy
http://www.wormbase.org/db/get?name=WBStrain00062723
Source Database: WormBase (WB)
Availability: unknown
Source References: EMPTY
Synonyms: E. coli [MG1655 bioB::kan].
Notes: Biotin auxotrophic E. coli strain is kan resistant and grows fine on LB. This mutant strain produces significantly less biotin and can therefore be used to reduce background in TurboID experiments. Also known as MG1655 bioB::kan and STL110 (J. Cronen, U. of Illinois). References: Sanchez AD & Feldman JL. STAR Protoc. 2021 Dec 2;2(4):100986. doi: 10.1016/j.xpro.2021.100986. PMID: 34927095. Ortega-Cuellar D., et al. J Nutrigenet Nutrigenomics. 2010;3(1):18-30. doi: 10.1159/000318054. PMID: 20798549|"Made_by: Ortega-Cuellar et al., 2010"
Proper citation: RRID:WB-STRAIN:WBStrain00062723 Copy
http://www.wormbase.org/db/get?name=WBStrain00062724
Source Database: WormBase (WB)
Affected Genes: WBGene00016741(haps-1)
Genomic Alteration: WBGene00016741(haps-1)
Availability: unknown
Source References: EMPTY
Synonyms: haps-1(ljt1) I.
Notes: CRISPR-engineered KO strain of haps-1 made by knock-in of tandem stop codons to the first exon of endogenous haps-1 locus. haps-1(C48B6.3) is the C. elegans ortholog of human HAPSTR1. haps-1(ljt1) is superficially wild-type when cultured at 20C, but is hypersensitive to paraquat (redox stress), MLN4924 (neddylation inhibition), and camptothecin (genotoxic stress). Reference: Amici DR, et al. Proc Natl Acad Sci U S A. 2022 Jul 5;119(27):e2111262119. doi: 10.1073/pnas.2111262119. PMID: 35776542.
Proper citation: RRID:WB-STRAIN:WBStrain00062724 Copy
http://www.wormbase.org/db/get?name=WBStrain00062689
Source Database: WormBase (WB)
Affected Genes: WBGene00001597(gld-3)
Genomic Alteration: WBGene00001597(gld-3)
Availability: unknown
Source References: EMPTY
Synonyms: gld-3(q1215[*q1065]) II.
Notes: 1xV5 tag inserted into endogenous gld-3 locus containing K864A & L867A engineered mutations, specifically tagging GLD-3L isoform. GLD-3L::1xV5 (K864A, L867A) animals are 30% Fog. Derived by CRISPR-engineered mutation of parental strain JK6091.|"Made_by: Brian Carrick"
Proper citation: RRID:WB-STRAIN:WBStrain00062689 Copy
http://www.wormbase.org/db/get?name=WBStrain00062722
Source Database: WormBase (WB)
Affected Genes: WBGene00004953(spd-2)|WBGene00004955(spd-5)
Genomic Alteration: WBGene00004953(spd-2), WBGene00004955(spd-5)
Availability: unknown
Source References: EMPTY
Synonyms: spd-5(wow36[tagRFP-T::spd-5]) spd-2(wow60[spd-2::GFP::3xFlag]) I.
Notes: Made_by: Jeremy Magescas|"tagRFP-T tag inserted into endogenous spd-5 locus. GFP and 3xFLAG tags inserted into endogenous spd-2 locus. No overt phenotypes. GFP and RFP fluorescence is observed at centrosomes. Reference: Magescas J, et al. eLife. 2019 Jun 27;8:e47867. doi: 10.7554/eLife.47867. PMID: 31246171."
Proper citation: RRID:WB-STRAIN:WBStrain00062722 Copy
http://www.wormbase.org/db/get?name=WBStrain00062715
Source Database: WormBase (WB)
Affected Genes: WBGene00004121(ptrn-1)
Genomic Alteration: WBGene00004121(ptrn-1)
Availability: unknown
Source References: EMPTY
Synonyms: ptrn-1(wow4[ptrn-1::GFP]) X.
Notes: GFP tag inserted into endogenous ptrn-1 locus. No overt phenotypes. GFP fluorescence is observed at non-centrosomal microtubule-organizing centers, including the apical surface of intestinal cells. Reference: Sallee M, et al. PLoS Biol. 2018 Aug 6;16(8):e2005189. doi: 10.1371/journal.pbio.2005189. PMID: 30080857.
Proper citation: RRID:WB-STRAIN:WBStrain00062715 Copy
http://www.wormbase.org/db/get?name=WBStrain00062719
Source Database: WormBase (WB)
Affected Genes: WBGene00001589(gip-1)|WBGene00006977(zif-1)
Genomic Alteration: WBGene00001589(gip-1), WBGene00006977(zif-1)
Availability: unknown
Source References: EMPTY
Synonyms: gip-1(wow5[ZF::GFP::gip-1]) zif-1(gk117) III.
Notes: ZF-degron and GFP tags inserted into endogenous gip-1 locus. No overt phenotypes in a zif-1(gk117) background. GFP fluorescence is observed at microtubule-organizing centers. Presence of ZF-degron targets tagged proteins for ZIF-mediated degradation. Expression of ZIF-1 causes the tagged GIP-1 protein to be degraded. Reference: Sallee M, et al. PLoS Biol. 2018 Aug 6;16(8):e2005189. doi: 10.1371/journal.pbio.2005189. PMID: 30080857.
Proper citation: RRID:WB-STRAIN:WBStrain00062719 Copy
http://www.wormbase.org/db/get?name=WBStrain00062671
Source Database: WormBase (WB)
Affected Genes: WBGene00003798(npp-12)
Genomic Alteration: WBGene00003798(npp-12)
Availability: unknown
Source References: EMPTY
Synonyms: npp-12(ax4544) I.
Notes: ax4544 is a CRISPR-engineered null mutant of npp-12. Reference: Thomas, Bodas, and Seydoux (2025). FG repeats drive co-clustering of nuclear pores and P granules in the C. elegans germline.|"Made_by: Basma Taleb Ismail"
Proper citation: RRID:WB-STRAIN:WBStrain00062671 Copy
http://www.wormbase.org/db/get?name=WBStrain00062679
Source Database: WormBase (WB)
Affected Genes: WBGene00003785(nos-3)
Genomic Alteration: WBGene00003785(nos-3)
Availability: unknown
Source References: EMPTY
Synonyms: nos-3(q958[nos-3::1xOLLAS]) II.
Notes: 1xOLLAS tag inserted into endogenous nos-3 locus via CRISPR/Cas9 engineering.|"Made_by: Brian Carrick"
Proper citation: RRID:WB-STRAIN:WBStrain00062679 Copy
http://www.wormbase.org/db/get?name=WBStrain00062713
Source Database: WormBase (WB)
Affected Genes: WBGene00000098(air-1)|WBGene00006977(zif-1)
Genomic Alteration: WBGene00000098(air-1), WBGene00006977(zif-1)
Availability: unknown
Source References: EMPTY
Synonyms: zif-1(gk117) III; air-1(wow14[AIR-1::ZF::GFP::3xFLAG]) V.
Notes: ZF-degron, GFP, and 3xFLAG tags inserted into endogenous air-1 locus. No overt phenotypes in a zif-1(gk117) background. GFP expression is observed in mitotic cells at the spindle poles and along microtubules. Presence of ZF-degron targets tagged proteins for ZIF-mediated degradation. Expression of ZIF-1 causes the tagged AIR-1 protein to be degraded. Reference: Sallee M, et al. PLoS Biol. 2018 Aug 6;16(8):e2005189. doi: 10.1371/journal.pbio.2005189. PMID: 30080857.
Proper citation: RRID:WB-STRAIN:WBStrain00062713 Copy
http://www.wormbase.org/db/get?name=WBStrain00062825
Source Database: WormBase (WB)
Affected Genes: WBGene00000898(daf-2)|WBGene00000912(daf-16)
Genomic Alteration: WBGene00000898(daf-2), WBGene00000912(daf-16)
Availability: unknown
Source References: EMPTY
Synonyms: daf-16(ot853[daf-16::mNG::AID]) I; otSi2 II; daf-2(e1370) III.
Notes: otSi2 [ges-1p::TIR1(F79G)::mRuby::unc-54 3'UTR + Cbr-unc-119(+) *ieSi61] II. Temperature-senstive daf(c): maintain at 15C. Intestine-specific TIR1 sequence in ieSi61 allele was edited to TIR1(F79G) using CRISPR/Cas9 to make it compatible with AID2. [TCC GTC GAG CTC AAG GGA AAG CCA CAC TTC] edited to [AGT GTC GAA TTG AAG GGA AAG CCA CAC GGA]. This strain can be used to deplete DAF-16 specifically from the intestine with the modified auxin 5-Ph-IAA. Constitutive dauer formation at 25 C due to daf-2(e1370). Reference: Sural S, et al. bioRxiv 2025.01.06.631508; doi: https:
Proper citation: RRID:WB-STRAIN:WBStrain00062825 Copy
http://www.wormbase.org/db/get?name=WBStrain00062781
Source Database: WormBase (WB)
Affected Genes: WBGene00017381(ddr-2)
Genomic Alteration: WBGene00017381(ddr-2)
Availability: unknown
Source References: EMPTY
Synonyms: ddr-2(qy64[LoxP]) X.
Notes: CRISPR-engineered deletion of ddr-2. Low penetrance Rup. Reference: Park K, et al. eLife. 2023 Jul 5;12:RP87037. doi: 10.7554/eLife.87037. PMID: 37405383.|"Made_by: Sara Payne"
Proper citation: RRID:WB-STRAIN:WBStrain00062781 Copy
http://www.wormbase.org/db/get?name=WBStrain00062785
Source Database: WormBase (WB)
Availability: unknown
Source References: EMPTY
Synonyms: qySi180 I.
Notes: Made_by: Sherwood Lab|"qySi180 [lin-29p::GFP::CAAX] I. MosSCI single copy insertion. Anchor cell specific expression of CAAX motif. Superficially wild-type. Reference: Park K, et al. J Cell Biol. 2024 Oct 7;223(10):e202402035. PMID: 39007804."
Proper citation: RRID:WB-STRAIN:WBStrain00062785 Copy
http://www.wormbase.org/db/get?name=WBStrain00062786
Source Database: WormBase (WB)
Affected Genes: WBGene00004892(sms-1)
Genomic Alteration: WBGene00004892(sms-1)
Availability: unknown
Source References: EMPTY
Synonyms: sms-1(qy198[sms-1::mNG]) IV.
Notes: Made_by: Sherwood Lab|"sms-1 locus endogenously tagged with mNG at the C-terminus. Superficially wild-type. Reference: Park K, et al. J Cell Biol. 2024 Oct 7;223(10):e202402035. PMID: 39007804."
Proper citation: RRID:WB-STRAIN:WBStrain00062786 Copy
http://www.wormbase.org/db/get?name=WBStrain00062783
Source Database: WormBase (WB)
Availability: unknown
Source References: EMPTY
Synonyms: qyIs555.
Notes: Made_by: Sherwood Lab|"qyIs555 [cdh-3p::aman-2::GFP]. Anchor cell specific expression of golgi protein aman-2. Superficially wild-type. Reference: Park K, et al. J Cell Biol. 2024 Oct 7;223(10):e202402035. PMID: 39007804."
Proper citation: RRID:WB-STRAIN:WBStrain00062783 Copy
http://www.wormbase.org/db/get?name=WBStrain00062784
Source Database: WormBase (WB)
Availability: unknown
Source References: EMPTY
Synonyms: qyIs562.
Notes: Made_by: Sherwood Lab|"qyIs562 [zmp-1p::zmp-1sp::sfGFP::KDEL]. Anchor cell specific expression of KDEL ER lumen marker. Superficially wild-type. Reference: Park K, et al. J Cell Biol. 2024 Oct 7;223(10):e202402035. PMID: 39007804."
Proper citation: RRID:WB-STRAIN:WBStrain00062784 Copy
http://www.wormbase.org/db/get?name=WBStrain00062822
Source Database: WormBase (WB)
Affected Genes: WBGene00022103(cdh-12)
Genomic Alteration: WBGene00022103(cdh-12)
Availability: unknown
Source References: EMPTY
Synonyms: cdh-12(ot1119[cdh-12::T2A::GFP::H2B]) III.
Notes: Made_by: SUNY Biotech|"SL2::GFP::H2B tag inserted at C-terminus of endogenous cdh-12 locus."
Proper citation: RRID:WB-STRAIN:WBStrain00062822 Copy
http://www.wormbase.org/db/get?name=WBStrain00062820
Source Database: WormBase (WB)
Affected Genes: WBGene00000395(cdh-3)
Genomic Alteration: WBGene00000395(cdh-3)
Availability: unknown
Source References: EMPTY
Synonyms: cdh-3(ot1096[cdh-3::T2A::GFP::H2B]) III.
Notes: Made_by: Maryam Majeed|"SL2::GFP::H2B tag inserted at C-terminus of endogenous cdh-3 locus."
Proper citation: RRID:WB-STRAIN:WBStrain00062820 Copy
http://www.wormbase.org/db/get?name=WBStrain00062788
Source Database: WormBase (WB)
Affected Genes: WBGene00017268(hmgr-1)
Genomic Alteration: WBGene00017268(hmgr-1)
Availability: unknown
Source References: EMPTY
Synonyms: hmgr-1(qy202[mNG::hmgr-1]) III.
Notes: hmgr-1 locus endogenously tagged with mNG at the N-terminus. Superficially wild-type. Reference: Park K, et al. J Cell Biol. 2024 Oct 7;223(10):e202402035. PMID: 39007804.|"Made_by: Sherwood Lab"
Proper citation: RRID:WB-STRAIN:WBStrain00062788 Copy
http://www.wormbase.org/db/get?name=WBStrain00062815
Source Database: WormBase (WB)
Affected Genes: WBGene00019994(cdh-1)
Genomic Alteration: WBGene00019994(cdh-1)
Availability: unknown
Source References: EMPTY
Synonyms: cdh-1(ot1092[cdh-1::T2A::GFP::H2B]) III.
Notes: Made_by: Maryam Majeed|"SL2::GFP::H2B tag inserted at C-terminus of endogenous cdh-1 locus."
Proper citation: RRID:WB-STRAIN:WBStrain00062815 Copy
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