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Integrated Animals is a virtual database currently indexing available animal strains and mutants from: AGSC (Ambystoma), BCBC (mice), BDSC (flies), European Xenopus Resource Center (frog), The National Xenopus Resource (frog), Xenopus Express (frog), CWRU Cystic Fibrosis Mouse Models (mice), DGGR (flies), FlyBase (flies), IMSR (mice), MGI (mice), MMRRC (mice), NSRRC (pig), RGD (rats), Sperm Stem Cell Libraries for Biological Research (rats), Tetrahymena Stock Center (Tetrahymena), WormBase (worms), XGSC (Xiphophorus), ZFIN (zebrafish), and ZIRC (zebrafish). Note, the IMSR data is linked, but users may need to re-execute the search if the top mouse is not returned properly.
Note: BCBC is no longer in service, so the links may not be functional.
http://www.wormbase.org/db/get?name=WBStrain00062585
Source Database: WormBase (WB)
Affected Genes: WBGene00002246(lag-2)|WBGene00003001(lin-12)
Genomic Alteration: WBGene00002246(lag-2), WBGene00003001(lin-12)
Availability: unknown
Source References: EMPTY
Synonyms: cshIs128 II; lin-12(ljf33[lin-12::mNeonGreen[C1]::LoxP::3xFLAG::AID]) III; lag-2(bmd202[lag-2::P2A::H2B::mTurquoise2::lox511i::2xHA]) V.
Notes: cshIs128 [rpl-28p::TIR1::T2A::mCherry::his-11)] II. Auxin-dependent degradation of endogenous LIN-12 with visible readout of endogenous lag-2 expression. Reference: Pani AM, et al. A new toolkit to visualize and perturb endogenous LIN-12/Notch signaling in C. elegans. MicroPubl Biol. 2022 Jul 28;2022:10.17912/micropub.biology.000603. doi: 10.17912/micropub.biology.000603. PMID: 35966394.|"Made_by: Theresa Gibney and Taylor Medwig-Kinney"
Proper citation: RRID:WB-STRAIN:WBStrain00062585 Copy
http://www.wormbase.org/db/get?name=WBStrain00062586
Source Database: WormBase (WB)
Affected Genes: WBGene00002246(lag-2)|WBGene00003001(lin-12)
Genomic Alteration: WBGene00002246(lag-2), WBGene00003001(lin-12)
Availability: unknown
Source References: EMPTY
Synonyms: cshIs140 II; lin-12(ljf33[lin-12::mNeonGreen[C1]::loxP::3xFLAG::AID*]) III; lag-2(bmd202[lag-2::P2A::H2B::mTurquoise2::lox511i::2xHA]) V.
Notes: cshIs140 [rpl-28p::TIR1(F79G)::T2A::mCherry::HIS-11] II. Allows for conditional degradation of endogenous LIN-12 using 5-Ph-IAA. Reference: Pani AM, et al. A new toolkit to visualize and perturb endogenous LIN-12/Notch signaling in C. elegans. MicroPubl Biol. 2022 Jul 28;2022:10.17912/micropub.biology.000603. doi: 10.17912/micropub.biology.000603. PMID: 35966394.|"Made_by: Theresa Gibney and Taylor Medwig-Kinney"
Proper citation: RRID:WB-STRAIN:WBStrain00062586 Copy
http://www.wormbase.org/db/get?name=WBStrain00062625
Source Database: WormBase (WB)
Availability: unknown
Source References: EMPTY
Synonyms: Y116F11B.14(bet83) V.
Notes: Homozygous viable. Deletion of 1493 bp in parental strain N2. Left flanking sequence: attaatttttgaatttcctaca; Right flanking sequence: tgacgggctaatattgaatta. sgRNA #1: attacactataataatgtgt; sgRNA #2: aaacgacaaactcattatga.|"Made_by: Bettinger lab"
Proper citation: RRID:WB-STRAIN:WBStrain00062625 Copy
http://www.wormbase.org/db/get?name=WBStrain00062622
Source Database: WormBase (WB)
Affected Genes: WBGene00022629(algn-12)
Genomic Alteration: WBGene00022629(algn-12)
Availability: unknown
Source References: EMPTY
Synonyms: algn-12(bet74) V/nT1[qls51] (IV;V).
Notes: Homozygous sterile. Balanced by nT1[qIs51]. Deletion of 3471 bp in parental strain N2. Left flanking sequence: tgatcactcacagttccctgg; Right flanking sequence: gaatggatatgatgatgtatat. sgRNA #1: atgttcgtggaacgacacca; sgRNA #2: aggataaactctctcttgaa.|"Made_by: Bettinger lab"
Proper citation: RRID:WB-STRAIN:WBStrain00062622 Copy
http://www.wormbase.org/db/get?name=WBStrain00062617
Source Database: WormBase (WB)
Availability: unknown
Source References: EMPTY
Synonyms: Y76A2B.4(bet65) III.
Notes: Homozygous viable. Deletion of 1579 bp in parental strain N2. Left flanking sequence: gcaaaaaaaaacataccaga; Right flanking sequence: cgtggtttcaggccattacg. sgRNA #1: cctcactgatgatcgtcatc; sgRNA #2: aaaggttcagcattcacacg.|"Made_by: Bettinger lab"
Proper citation: RRID:WB-STRAIN:WBStrain00062617 Copy
http://www.wormbase.org/db/get?name=WBStrain00062618
Source Database: WormBase (WB)
Affected Genes: WBGene00016665(chil-11)
Genomic Alteration: WBGene00016665(chil-11)
Availability: unknown
Source References: EMPTY
Synonyms: chil-11(bet66) IV.
Notes: Homozygous viable. Deletion of 2532 bp in parental strain N2. Left flanking sequence: agtcaattcggaactccatgt; Right flanking sequence: tctacggtttaaacaactcctc. sgRNA #1: aacgggatctgttcatcaca; sgRNA #2: agtgtgaaacgcaacgtcta.|"Made_by: Bettinger lab"
Proper citation: RRID:WB-STRAIN:WBStrain00062618 Copy
http://www.wormbase.org/db/get?name=WBStrain00062616
Source Database: WormBase (WB)
Availability: unknown
Source References: EMPTY
Synonyms: Y67H2A.2(bet63) IV.
Notes: Homozygous viable. Deletion of 2572 bp in parental strain N2. Left flanking sequence: atctatttttttaaggccgaac; Right flanking sequence: tattggcagcaagcgttgcgaa. sgRNA #1: ccatacgttgttgtggagtt; sgRNA #2: tgtgaagcggaaaaccctat.|"Made_by: Bettinger lab"
Proper citation: RRID:WB-STRAIN:WBStrain00062616 Copy
http://www.wormbase.org/db/get?name=WBStrain00062572
Source Database: WormBase (WB)
Availability: unknown
Source References: EMPTY
Synonyms: dmaEx617.
Notes: dmaEx617 [fshr-1p::fshr-1::GFP + unc-54p::mCherry]. Pick mCherry+ animals to maintain. Extrachromosomal fshr-1p::fshr-1::GFP translation reporter. Reference: Wang C, et al. Aging Cell. 2023 Jan;22(1):e13735. doi: 10.1111/acel.13735. PMID: 36415159.|"Made_by: Dengke Ma Lab"
Proper citation: RRID:WB-STRAIN:WBStrain00062572 Copy
http://www.wormbase.org/db/get?name=WBStrain00062576
Source Database: WormBase (WB)
Affected Genes: WBGene00003271(mir-43)
Genomic Alteration: WBGene00003271(mir-43)
Availability: unknown
Source References: EMPTY
Synonyms: mir-43(sjm1) II.
Notes: Homozygotes lack obvious gross phenotypes; miR-43(sjm1) accumulates in L4 larvae compared to wild-type miR-43. mir-43(sjm1) has an inversion of the miR-43 seed sequence. Reference: Stubna MW, et al. bioRxiv doi: 10.1101/2024.06.28/601170.|"Made_by: Michael Stubna"
Proper citation: RRID:WB-STRAIN:WBStrain00062576 Copy
http://www.wormbase.org/db/get?name=WBStrain00062577
Source Database: WormBase (WB)
Affected Genes: WBGene00003271(mir-43)
Genomic Alteration: WBGene00003271(mir-43)
Availability: unknown
Source References: EMPTY
Synonyms: mir-43(sjm2) II.
Notes: Homozygotes lack obvious gross phenotypes. mir-43(sjm2) has positions 9-23 of miR-43 substituted for random sequence. This strain is also homozygous for a G>T point substitution at position 8 of miR-42. Reference: Stubna MW, et al. bioRxiv doi: 10.1101/2024.06.28/601170.|"Made_by: Michael Stubna"
Proper citation: RRID:WB-STRAIN:WBStrain00062577 Copy
http://www.wormbase.org/db/get?name=WBStrain00062610
Source Database: WormBase (WB)
Availability: unknown
Source References: EMPTY
Synonyms: Caenorhabditis sp. 78 wild isolate.
Notes: Made_by: Marie-Anne Felix and Hagus Tarno's lab|"Male-female. Maintain at 20C or warmer. Elegans group. Isofemale line isolated from rotting flowers of Stewartia pseudocamellia collected near Malino, South Sulawesi, Indonesia, on 6 May 2024. GPS -5.242944, 119.868592. Reference: Devi, et al., in preparation."
Proper citation: RRID:WB-STRAIN:WBStrain00062610 Copy
http://www.wormbase.org/db/get?name=WBStrain00062613
Source Database: WormBase (WB)
Availability: unknown
Source References: EMPTY
Synonyms: Caenorhabditis sp. 80 wild isolate.
Notes: Made_by: Marie-Anne Felix and Hagus Tarno's lab|"Male-female. Maintain at 20C or warmer. Elegans group. Isofemale line isolated from rotting wild Musa pseudostems collected in the forest on the road between Bromo and Malang, East Java, Indonesia, on 11 May 2024. GPS -7.99746, 112.87387. Reference: Devi, et al., in preparation."
Proper citation: RRID:WB-STRAIN:WBStrain00062613 Copy
http://www.wormbase.org/db/get?name=WBStrain00062614
Source Database: WormBase (WB)
Affected Genes: WBGene00003625(nhr-31)
Genomic Alteration: WBGene00003625(nhr-31)
Availability: unknown
Source References: EMPTY
Synonyms: nhr-31(ye123) IV.
Notes: Made_by: Youmie Kim|"Maintain at 15C. Temperature-sensitive: slow growth rate, reduced brood size. Resistant to Cry proteins. Isolated from EMS screen in N2 background. Reference: Kim YM, et al. PLoS Pathog. 2024 Oct 18;20(10):e1012611. doi: 10.1371/journal.ppat.1012611. PMID: 39423230."
Proper citation: RRID:WB-STRAIN:WBStrain00062614 Copy
http://www.wormbase.org/db/get?name=WBStrain00062579
Source Database: WormBase (WB)
Affected Genes: WBGene00003271(mir-43)|WBGene00004140(ebax-1)
Genomic Alteration: WBGene00003271(mir-43), WBGene00004140(ebax-1)
Availability: unknown
Source References: EMPTY
Synonyms: mir-43(sjm1) II; ebax-1(tm2321) IV.
Notes: Homozygotes lack obvious gross phenotypes, though some miRNAs are elevated due to a loss-of-function mutation in ebax-1. mir-43(sjm1) is an inversion of the seed sequence of miR-43. Generated by mating parental strain CZ9907 hermaphrodites to mir-43(sjm1) males. Reference: Stubna MW, et al. bioRxiv doi: 10.1101/2024.06.28/601170.|"Made_by: Michael Stubna"
Proper citation: RRID:WB-STRAIN:WBStrain00062579 Copy
http://www.wormbase.org/db/get?name=WBStrain00062607
Source Database: WormBase (WB)
Affected Genes: WBGene00006514(tdp-1)
Genomic Alteration: WBGene00006514(tdp-1)
Availability: unknown
Source References: EMPTY
Synonyms: tdp-1(tgx58) I.
Notes: Made_by: nVivo Biosystems/ Nemametrix and Hart lab|"Null allele. CRISPR-engineered deletion of the tdp-1 locus precisely eliminates all known tdp-1 exons and introns. Reference: Lins J, et al. Generation of a C. elegans tdp-1 null allele and humanized TARDBP containing human disease-variants. MicroPubl Biol. 2023 Jun 6;2023:10.17912/micropub.biology.000693. doi: 10.17912/micropub.biology.000693. PMID: 37351305."
Proper citation: RRID:WB-STRAIN:WBStrain00062607 Copy
http://www.wormbase.org/db/get?name=WBStrain00062604
Source Database: WormBase (WB)
Affected Genes: WBGene00001975(hmg-5)
Genomic Alteration: WBGene00001975(hmg-5)
Availability: unknown
Source References: EMPTY
Synonyms: hmg-5(xn107[hmg-5::gfp]) IV.
Notes: GFP-tagged HMG-5/TFAM labels mtDNA nucleoids. GFP tag causes a reduction in number of mtDNAs. Reference: Schwartz AZA, et al. eLife. 2022 Oct 6:11:e80396. doi: 10.7554/eLife.80396. PMID: 36200990.|"Made_by: Aaron Schwartz"
Proper citation: RRID:WB-STRAIN:WBStrain00062604 Copy
http://www.wormbase.org/db/get?name=WBStrain00062608
Source Database: WormBase (WB)
Affected Genes: WBGene00008266(rike-1)
Genomic Alteration: WBGene00008266(rike-1)
Availability: unknown
Source References: EMPTY
Synonyms: rike-1(syb1165) V/nT1[qIs51] (IV;V).
Notes: Heterozygotes are wild-type with pharyngeal GFP signal, and segregate WT GFP, arrested nT1[qIs51] aneuploids, and non-GFP rike-1(syb1165) homozygotes (early larval lethality). Homozygous nT1[qIs51] inviable. Pick WT GFP and check for correct segregation of progeny to maintain. Reference: Cheng X, et al. Autophagy. 2023 Jan;19(1):241-255. doi: 10.1080/15548627.2022.2071381. PMID: 35521960.|"Made_by: SunyBiotech"
Proper citation: RRID:WB-STRAIN:WBStrain00062608 Copy
http://www.wormbase.org/db/get?name=WBStrain00062609
Source Database: WormBase (WB)
Availability: unknown
Source References: EMPTY
Synonyms: Caenorhabditis sp. 77 wild isolate.
Notes: Made_by: Marie-Anne Felix and Hagus Tarno's lab|"Male-female. Maintain at 20C or warmer. Elegans group. Isofemale line isolated from rotting banana flowers collected in a forest near Batu, East Java, Indonesia, on 28 Apr 2024. GPS -7.803387, 112.516604. Reference: Devi, et al., in preparation."
Proper citation: RRID:WB-STRAIN:WBStrain00062609 Copy
http://www.wormbase.org/db/get?name=WBStrain00062562
Source Database: WormBase (WB)
Affected Genes: WBGene00019322(ahcy-1)
Genomic Alteration: WBGene00019322(ahcy-1)
Availability: unknown
Source References: EMPTY
Synonyms: ahcy-1(syb748) I.
Notes: ahcy-1(syb748) is a CRISPR/Cas9-engineered C280A substitution that eliminates electrophile sensing but retains enzymatic activity.|"Made_by: SunyBiotech Co., Ltd"
Proper citation: RRID:WB-STRAIN:WBStrain00062562 Copy
http://www.wormbase.org/db/get?name=WBStrain00062566
Source Database: WormBase (WB)
Affected Genes: WBGene00000601(col-12)
Genomic Alteration: WBGene00000601(col-12)
Availability: unknown
Source References: EMPTY
Synonyms: col-12::mNG(ju1932) V.
Notes: Made_by: Jennifer Gotenstein Adams|"mNG inserted at C-terminus of endogenous col-12 locus."
Proper citation: RRID:WB-STRAIN:WBStrain00062566 Copy
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