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Integrated Animals is a virtual database currently indexing available animal strains and mutants from: AGSC (Ambystoma), BCBC (mice), BDSC (flies), European Xenopus Resource Center (frog), The National Xenopus Resource (frog), Xenopus Express (frog), CWRU Cystic Fibrosis Mouse Models (mice), DGGR (flies), FlyBase (flies), IMSR (mice), MGI (mice), MMRRC (mice), NSRRC (pig), RGD (rats), Sperm Stem Cell Libraries for Biological Research (rats), Tetrahymena Stock Center (Tetrahymena), WormBase (worms), XGSC (Xiphophorus), ZFIN (zebrafish), and ZIRC (zebrafish). Note, the IMSR data is linked, but users may need to re-execute the search if the top mouse is not returned properly.
Note: BCBC is no longer in service, so the links may not be functional.
http://www.wormbase.org/db/get?name=WBStrain00035044
Source Database: WormBase (WB)
Affected Genes: WBGene00000950(deg-1)
Genomic Alteration: WBGene00000950(deg-1)
Availability: available
Source References: PMID:7627559
Synonyms: deg-1(u506) X.
Alternate IDs: WB-STRAIN:TU1366, CGC_TU1366
Notes: Recessive gain-of-function. Codon 393 changed from alanine (GCT) to threonine (ACT). Deg and Tab at all temperatures. Lethal at 15C (embryos arrest at the two-fold stage, larvae survive).
Proper citation: RRID:WB-STRAIN:WBStrain00035044 Copy
http://www.wormbase.org/db/get?name=WBStrain00035055
Source Database: WormBase (WB)
Availability: available
Source References: PMID:33319173, PMID:38378098
Synonyms: uls60 [unc-119p::YFP+unc-119p::sid-1]
Alternate IDs: WB-STRAIN:TU3311, CGC_TU3311
Notes: Generated from papers flagged positive during the last month for data type afp_strain/other_strain.|"Made_by: Calixto & Topalidou"|"uIs60 [unc-119p::YFP + unc-119p::sid-1]. Hypersensitive neuronal RNAi by feeding. Superficially wild-type. YFP detectable in neurons. Maintain 15-20 degrees. Reference: Calixto et al. (2010) Nature Methods 7:554-9."|"WBStrain provided so WBPaper00060459 paper added based on AFP_Strain data."|"WBStrain provided so WBPaper00060797 paper added based on AFP_Strain data."
Proper citation: RRID:WB-STRAIN:WBStrain00035055 Copy
http://www.wormbase.org/db/get?name=WBStrain00035058
Source Database: WormBase (WB)
Affected Genes: WBGene00004795(sid-1)
Genomic Alteration: WBGene00004795(sid-1)
Availability: available
Source References: PMID:37857834
Synonyms: ccIs4251 I; sid-1(qt2) V; uIs71.
Alternate IDs: WB-STRAIN:TU3403, CGC_TU3403
Notes: ccIs4251 [(pSAK2) myo-3p::GFP::LacZ::NLS + (pSAK4) myo-3p::mitochondrial GFP + dpy-20(+)] I. uIs71 [(pCFJ90) myo-2p::mCherry + mec-18p::sid-1]. TRN-specific feeding RNAi. Reference: Calixto et al. (2010) Nature Methods 7:554-9.|"Supplementary_genotype ccIs4251 ((pSAK2) myo-3p::GFP::LacZ::NLS + (pSAK4) myo-3p::mitochondrial GFP + dpy-20(+)) Isid-1 (qt2) V uIs71 ((pCFJ90) myo-2p::mCherry + mec-18p::sid-1)"
Proper citation: RRID:WB-STRAIN:WBStrain00035058 Copy
http://www.wormbase.org/db/get?name=WBStrain00035057
Source Database: WormBase (WB)
Affected Genes: WBGene00004795(sid-1)
Genomic Alteration: WBGene00004795(sid-1)
Availability: available
Source References: PMID:33674585, PMID:34172445, PMID:34321666, PMID:34496255, PMID:36653384, PMID:37118550, PMID:37118502, PMID:37432924, PMID:37651423, PMID:37722055, PMID:38446031, PMID:38510643, PMID:38740431, PMID:39395417, PMID:39423228
Synonyms: sid-1(pk3321);uIs69
Alternate IDs: WB-STRAIN:TU3401, CGC_TU3401
Notes: no longer available from the CGC.|"Supplementary_genotype sid-1(pk3321) V; uIs69 [pCFJ90 (myo-2p::mCherry) + unc-119p::sid-1] V"|"uIs69 [pCFJ90 (myo-2p::mCherry) + unc-119p::sid-1]. Hypersensitive neuronal RNAi by feeding. Superficially wild-type. Maintain 15-20 degrees. [NOTE: uIs69 is closely linked and maps to the right of dpy-11. (C. Loer 08/2011) See strains LC105 and LC108.] Reference: Calixto et al. (2010) Nature Methods 7:554-9."|"WBStrain mapped, WBPaper00061562 added based on AFP_Strain data."|"WBStrain provided so WBPaper00060797 paper added based on AFP_Strain data."|"WBStrain provided so WBPaper00061750 paper added based on AFP_Strain data."|"WBStrain provided so WBPaper00061894 paper added based on AFP_Strain data."
Proper citation: RRID:WB-STRAIN:WBStrain00035057 Copy
http://www.wormbase.org/db/get?name=WBStrain00035030
Source Database: WormBase (WB)
Affected Genes: WBGene00000950(deg-1)
Genomic Alteration: WBGene00000950(deg-1)
Availability: available
Source References: PMID:2342572, PMID:32009302, PMID:37500635, PMID:38443452
Synonyms: deg-1(u38) X.
Alternate IDs: WB-STRAIN:TU38, CGC_TU38
Notes: Touch insensitive-at the tail. Degeneration of a small set of neurons. TAB Touch ABnormal).
Proper citation: RRID:WB-STRAIN:WBStrain00035030 Copy
http://www.wormbase.org/db/get?name=WBStrain00035034
Source Database: WormBase (WB)
Affected Genes: WBGene00003172(mec-8)
Genomic Alteration: WBGene00003172(mec-8)
Availability: available
Synonyms: mec-8(u314) I.
Alternate IDs: WB-STRAIN:TU166, CGC_TU166
Notes: Reference: Lundquist and Herman 1994 Genetics 138: 83.
Proper citation: RRID:WB-STRAIN:WBStrain00035034 Copy
http://www.wormbase.org/db/get?name=WBStrain00035009
Source Database: WormBase (WB)
Affected Genes: WBGene00008223(lgc-48)
Genomic Alteration: WBGene00008223(lgc-48)
Availability: unknown
Synonyms: unc-119(ed3);tag_1477[WRM062A_D04(pRedFlp-Hgr)(C50B6.11[22755]::S0001_pR6K_Amp_2xTY1ce_EGFP_FRT_rpsl_neo_FRT_3xFlag)dFRT::unc-119-Nat]
Alternate IDs: WB-STRAIN:TRG1477
Notes: Imported directly from the transgeneOme database.
Proper citation: RRID:WB-STRAIN:WBStrain00035009 Copy
http://www.wormbase.org/db/get?name=WBStrain00035066
Source Database: WormBase (WB)
Affected Genes: WBGene00003864(oma-1)
Genomic Alteration: WBGene00003864(oma-1)
Availability: available
Source References: PMID:37878696
Synonyms: oma-1(zu405) IV.
Alternate IDs: WB-STRAIN:TX20, CGC_TX20
Notes: Maintain at 15C. Give about 50% dead embryos at 15C. Gives 100% dead embryos at 20C and 25C.|"Supplementary_genotype oma-1(zu405)"
Proper citation: RRID:WB-STRAIN:WBStrain00035066 Copy
http://www.wormbase.org/db/get?name=WBStrain00035068
Source Database: WormBase (WB)
Affected Genes: WBGene00003864(oma-1)|WBGene00003865(oma-2)
Genomic Alteration: WBGene00003864(oma-1), WBGene00003865(oma-2)
Availability: available
Synonyms: oma-1(zu405te33)/nT1 [unc-?(n754) let-?] IV; oma-2(te51)/nT1 V.
Alternate IDs: WB-STRAIN:TX183, CGC_TX183
Notes: Heterozygotes are Unc and segregate Unc and non-Unc steriles (oma-1; oma-2 homozygotes). The Oma animal has an empty uterus and lots of oocytes in the gonad arms. Maintain by picking Uncs. zu405 is a gain-of-function mutation which results in temperature sensitive, embryonic lethality. Loss-of-function mutation in either oma-1 or oma-2 alone does not have a detectable phenotype. te33 is a dominant suppressor of the zu405 embryonic lethality. te51 is a mutation that, in the oma-1(zu405te33) background, gives an Oma (Ooctye Maturation defective) phenotype.|"Heterozygotes are Unc and segregate Unc and non-Unc steriles (oma-1; oma-2 homozygotes). The Oma animal has an empty uterus and lots of oocytes in the gonad arms. Maintain by picking Uncs. zu405 is a gain-of-function mutation which results in temperature sensitive, embryonic lethality. Loss-of-function mutation in either oma-1 or oma-2 alone does not have a detectable phenotype. te33 is a dominant suppressor of the zu405 embryonic lethality. te51 is a mutation that, in the oma-1(zu405te33) background, gives an Oma (Ooctye Maturation defective) phenotype. [NOTE (09/2016; D. Greenstein, unpublished results): The two molecular changes in te33 are different than reported by Detwiler et al. (2001), but nonetheless result in a strong loss of oma-1 function. Sequencing of the original isolate of te33 gave the same result (S. Robertson and R. Lin, unpublished results).] This strain carrying oma-1(zu405te33) contains the following mutations: zu405 [C8889984T; P240L] and te33 [C8889978A, S238stop & C8889863T, H200Y]."
Proper citation: RRID:WB-STRAIN:WBStrain00035068 Copy
http://www.wormbase.org/db/get?name=WBStrain00035183
Source Database: WormBase (WB)
Availability: available
Source References: PMID:31323240
Synonyms: baIs4.
Alternate IDs: WB-STRAIN:UA57, CGC_UA57
Notes: baIs4 [dat-1p::GFP + dat-1p::CAT-2]. GFP expression in CEP, ADE and PDE neurons. From integration of baEx33.|"Made_by: Caldwell Lab"|"WBStrain mapped, WBPaper00060404 added based on AFP_Strain data."
Proper citation: RRID:WB-STRAIN:WBStrain00035183 Copy
http://www.wormbase.org/db/get?name=WBStrain00035160
Source Database: WormBase (WB)
Affected Genes: WBGene00000254(bli-4)|WBGene00002034(htp-3)
Genomic Alteration: WBGene00000254(bli-4), WBGene00002034(htp-3)
Availability: available
Synonyms: htp-3(tm3655) I/hT2 [bli-4(e937) let-?(q782) qIs48] (I,III).
Alternate IDs: WB-STRAIN:TY5038, CGC_TY5038
Notes: Made_by: Aaron Stevenson|"Segregates WT GFP+ heterozygotes, GFP- tm3655 homozygotes, very rare GFP+ homozygous hT2, and dead eggs. Maintain by picking wild-type GFP+. Avoid picking viable aneuploids that often appear larger and longer than wild-type."
Proper citation: RRID:WB-STRAIN:WBStrain00035160 Copy
http://www.wormbase.org/db/get?name=WBStrain00035162
Source Database: WormBase (WB)
Affected Genes: WBGene00000592(coh-3)|WBGene00004333(rec-8)|WBGene00021560(coh-4)
Genomic Alteration: WBGene00000592(coh-3), WBGene00004333(rec-8), WBGene00021560(coh-4)
Availability: available
Synonyms: rec-8(ok978)/nT1 IV; coh-4(tm1857) coh-3(gk112) V/nT1 [qIs51] V.
Alternate IDs: WB-STRAIN:TY5121, CGC_TY5121
Notes: Heterozygotes are superficially wild-type GFP+, and will segregate wild-type GFP+ heterozygotes, sterile rec-8(ok978); coh-4(tm1857) coh-3(gk112) homozygotes that are GFP-, nT1 GFP+ homozygotes, and aneuploid dead embryos.|"Made_by: Aaron Stevenson"
Proper citation: RRID:WB-STRAIN:WBStrain00035162 Copy
http://www.wormbase.org/db/get?name=WBStrain00035140
Source Database: WormBase (WB)
Affected Genes: WBGene00001484(fox-1)
Genomic Alteration: WBGene00001484(fox-1)
Availability: available
Source References: PMID:9217163, PMID:38134228
Synonyms: fox-1(y303) X.
Alternate IDs: WB-STRAIN:TY2685, CGC_TY2685
Notes: Made_by P. Liu
Proper citation: RRID:WB-STRAIN:WBStrain00035140 Copy
http://www.wormbase.org/db/get?name=WBStrain00035116
Source Database: WormBase (WB)
Affected Genes: WBGene00006962(xol-1)
Genomic Alteration: WBGene00006962(xol-1)
Availability: available
Source References: PMID:3167975
Synonyms: xol-1(y9) X.
Alternate IDs: WB-STRAIN:TY1807, CGC_TY1807
Notes: Fully penetrant XO lethal. XX is WT. Enhancer of her-1(sd), tra-2(lf), tra-3(lf) XX masculinization phenotypes. Does not enhance tra-1(lf).|"Made_by: Larry Casson"
Proper citation: RRID:WB-STRAIN:WBStrain00035116 Copy
http://www.wormbase.org/db/get?name=WBStrain00035202
Source Database: WormBase (WB)
Availability: unknown
Source References: PMID:30683808, PMID:37473700
Synonyms: (baIn34[Peat-4::A, Pmyo-2::mCherry]; adIs1240[Peat-4::GFP])
Alternate IDs: WB-STRAIN:UA198
Notes: Supplementary_genotype baIn34[eat-4p::A1-42 +myo-2p::mCherry]; adIs1240[eat-4p::GFP]
Proper citation: RRID:WB-STRAIN:WBStrain00035202 Copy
http://www.wormbase.org/db/get?name=WBStrain00035241
Source Database: WormBase (WB)
Availability: available
Synonyms: muIs32 II; gqIs25.
Alternate IDs: WB-STRAIN:UF65, CGC_UF65
Notes: muIs32 [mec-7p::GFP + lin-15(+)]. gqIs25 [rab-3p::ppk-1 + lin-15(+)].
Proper citation: RRID:WB-STRAIN:WBStrain00035241 Copy
http://www.wormbase.org/db/get?name=WBStrain00035421
Source Database: WormBase (WB)
Affected Genes: WBGene00002393(lpr-1)
Genomic Alteration: WBGene00002393(lpr-1)
Availability: available
Synonyms: lpr-1(cs207) I.
Alternate IDs: WB-STRAIN:UP2436, CGC_UP2436
Notes: cs207 is an early nonsense allele (Q72stop). Approximately 90% rod-like larval lethal, with 10% normal escapers. Exact percentages are sensitive to temperature and culture conditions.
Proper citation: RRID:WB-STRAIN:WBStrain00035421 Copy
http://www.wormbase.org/db/get?name=WBStrain00035425
Source Database: WormBase (WB)
Affected Genes: WBGene00012261(lpr-3)
Genomic Alteration: WBGene00012261(lpr-3)
Availability: available
Synonyms: lpr-3(cs231) X; csEx436.
Alternate IDs: WB-STRAIN:UP3542, CGC_UP3542
Notes: csEx436 [lpr-3 (fosmid WRM619dE09) + myo-2p::mCherry]. Pick mCherry+ animals to maintain. cs231 is a Crispr/Cas9-induced null allele of lpr-3: a 13 nucleotide deletion in exon 1 results in frameshift. Homozygous mutants are embryonic lethal, but are rescued by csEx436 containing lpr-3(+) fosmid WRM619dE09. NOTE: lpr-3(cs231) should be considered the canonical allele as ok2351 also perturbs expression of adjacent gene lpr-6. Reference: Forman-Rubinsky R, Cohen JD and Sundaram MV. Genetics. 2017 Oct;207(2):625-642.
Proper citation: RRID:WB-STRAIN:WBStrain00035425 Copy
http://www.wormbase.org/db/get?name=WBStrain00035486
Source Database: WormBase (WB)
Affected Genes: WBGene00001812(haf-2)
Genomic Alteration: WBGene00001812(haf-2)
Availability: available
Synonyms: haf-2(gk13) II.
Alternate IDs: WB-STRAIN:VC16, CGC_VC16
Notes: F43E2.4. Superficially wild type.|"Made_by: Vancouver KO Group"|"Mutagen: Formaldehyde"|"This strain was provided by the C. elegans Reverse Genetics Core Facility at the University of British Columbia, which is part of the international C. elegans Gene Knockout Consortium, which should be acknowledged in any publications resulting from its use."
Proper citation: RRID:WB-STRAIN:WBStrain00035486 Copy
http://www.wormbase.org/db/get?name=WBStrain00035481
Source Database: WormBase (WB)
Affected Genes: WBGene00003558(nca-2)
Genomic Alteration: WBGene00003558(nca-2)
Availability: available
Synonyms: nca-2(gk5) III.
Alternate IDs: WB-STRAIN:VC9, CGC_VC9
Notes: C27F2.2. Superficially wild type.|"Made_by: Vancouver KO Group"|"Mutagen: Formaldehyde"|"This strain was provided by the C. elegans Reverse Genetics Core Facility at the University of British Columbia, which is part of the international C. elegans Gene Knockout Consortium, which should be acknowledged in any publications resulting from its use."
Proper citation: RRID:WB-STRAIN:WBStrain00035481 Copy
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