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Integrated Animals is a virtual database currently indexing available animal strains and mutants from: AGSC (Ambystoma), BCBC (mice), BDSC (flies), European Xenopus Resource Center (frog), The National Xenopus Resource (frog), Xenopus Express (frog), CWRU Cystic Fibrosis Mouse Models (mice), DGGR (flies), FlyBase (flies), IMSR (mice), MGI (mice), MMRRC (mice), NSRRC (pig), RGD (rats), Sperm Stem Cell Libraries for Biological Research (rats), Tetrahymena Stock Center (Tetrahymena), WormBase (worms), XGSC (Xiphophorus), ZFIN (zebrafish), and ZIRC (zebrafish). Note, the IMSR data is linked, but users may need to re-execute the search if the top mouse is not returned properly.
Note: BCBC is no longer in service, so the links may not be functional.
http://www.wormbase.org/db/get?name=WBStrain00062938
Source Database: WormBase (WB)
Affected Genes: WBGene00022675(gbb-2)
Genomic Alteration: WBGene00022675(gbb-2)
Availability: unknown
Source References: EMPTY
Synonyms: gbb-2(syb5759[gbb-2::sl2::gfp::h2b]) IV.
Notes: Made_by: SunyBiotech|"SL2::GFP::H2B tags inserted at C-terminus of gbb-2 endogenous locus. Reference: Stefanakis N, et al. 2024 Feb 15. doi: 10.1038/s44318-024-00049-w. PMID: 38360995."
Proper citation: RRID:WB-STRAIN:WBStrain00062938 Copy
http://www.wormbase.org/db/get?name=WBStrain00062892
Source Database: WormBase (WB)
Affected Genes: WBGene00000088(aex-5)|WBGene00001918(his-44)
Genomic Alteration: WBGene00000088(aex-5), WBGene00001918(his-44)
Availability: unknown
Source References: EMPTY
Synonyms: aex-5(ot1532[aex-5::SL2::gfp::his-44]) I.
Notes: SL2::GFP::HIS-44 tag inserted into the endogenous aex-5 locus. Reference: Sural S, et al. bioRxiv 2025.01.06.631508; doi: https:
Proper citation: RRID:WB-STRAIN:WBStrain00062892 Copy
http://www.wormbase.org/db/get?name=WBStrain00062896
Source Database: WormBase (WB)
Availability: unknown
Source References: EMPTY
Synonyms: otIs927 V.
Notes: otIs927 [ges-1p::nlp-40::tagRFP-T::SL2::GFP::his-44::tbb-2 3 UTR + inx-6(prom18)::tagRFP-T::unc-54 3' UTR] V. Transgene allows monitoring of the secretion of NLP-40 neuropeptide from the intestine under different physiological conditions. The multicopy array was inserted at the oxTi553 landing site using the Fluorescent Landmark Interference (FLInt) method. Reference: Sural S, et al. bioRxiv 2025.01.06.631508; doi: https:
Proper citation: RRID:WB-STRAIN:WBStrain00062896 Copy
http://www.wormbase.org/db/get?name=WBStrain00062893
Source Database: WormBase (WB)
Affected Genes: WBGene00006807(unc-75)
Genomic Alteration: WBGene00006807(unc-75)
Availability: unknown
Source References: EMPTY
Synonyms: unc-75(ot1539[mScarlet-I3::unc-75]) I.
Notes: Made_by: Karinna Pe (Hobert Lab)|"mScarlet-I3 tag inserted into endogenous unc-75 locus via CRISPR/Cas9 engineering. Reference: Cao WX, et al. (2024). bioRxiv: 2024.2006.2011.598534. https:"
Proper citation: RRID:WB-STRAIN:WBStrain00062893 Copy
http://www.wormbase.org/db/get?name=WBStrain00062894
Source Database: WormBase (WB)
Affected Genes: WBGene00000084(aex-1)|WBGene00001918(his-44)
Genomic Alteration: WBGene00000084(aex-1), WBGene00001918(his-44)
Availability: unknown
Source References: EMPTY
Synonyms: aex-1(ot1543[aex-1::SL2::gfp::his-44]) I.
Notes: SL2::GFP::HIS-44 tag inserted into the endogenous aex-1 locus. Reference: Sural S, et al. bioRxiv 2025.01.06.631508; doi: https:
Proper citation: RRID:WB-STRAIN:WBStrain00062894 Copy
http://www.wormbase.org/db/get?name=WBStrain00062899
Source Database: WormBase (WB)
Affected Genes: WBGene00000295(cat-1)
Genomic Alteration: WBGene00000295(cat-1)
Availability: unknown
Source References: EMPTY
Synonyms: Cbr-cat-1(ot1621[Cbr-cat-1::SL2::mScarlet3::H2B]) X.
Notes: Made_by: Itai Toker|"SL2::mScarlet3::H2B tag inserted before STOP codon of endogenous Cbr-cat-1 locus using CRISPR/Cas9. Generated in C. briggsae AF16 background. Reference: Toker IA, et al. bioRxiv 2024.11.23.624988; doi: https:"
Proper citation: RRID:WB-STRAIN:WBStrain00062899 Copy
http://www.wormbase.org/db/get?name=WBStrain00062933
Source Database: WormBase (WB)
Affected Genes: WBGene00004394(rol-1)
Genomic Alteration: WBGene00004394(rol-1)
Availability: unknown
Source References: EMPTY
Synonyms: rol-1::mNG(syb5033) II.
Notes: Made_by: SunyBiotech|"mNG inserted at C-terminus of endogenous rol-1 locus."
Proper citation: RRID:WB-STRAIN:WBStrain00062933 Copy
http://www.wormbase.org/db/get?name=WBStrain00062897
Source Database: WormBase (WB)
Availability: unknown
Source References: EMPTY
Synonyms: otIs937 V.
Notes: otIs937 [ceh-19(prom2)::daf-2(DN)::eBFP2::SL2::tagRFP-T::tbb-2 3' UTR + unc-122p::GFP::unc-54 3' UTR] V. daf-2(DN) encodes a dominant negative form of the DAF-2 protein, causing inhibition of the insulin receptor DAF-2. daf-2(DN) encodes a dominant negative form of the DAF-2 protein, causing inhibition of the insulin receptor DAF-2. ceh-19(prom2) drives expression of daf-2(DN) specifically in the MC neurons in the pharyngeal nervous system. The multicopy array was inserted at the oxTi553 landing site using the Fluorescent Landmark Interference (FLInt) method. Reference: Sural S, et al. bioRxiv 2025.01.06.631508; doi: https:
Proper citation: RRID:WB-STRAIN:WBStrain00062897 Copy
http://www.wormbase.org/db/get?name=WBStrain00062925
Source Database: WormBase (WB)
Affected Genes: WBGene00001074(dpy-13)
Genomic Alteration: WBGene00001074(dpy-13)
Availability: unknown
Source References: EMPTY
Synonyms: dpy-13::mNG(syb3318) IV.
Notes: Made_by: SunyBiotech|"mNG inserted at C-terminus of endogenous dpy-13 locus."
Proper citation: RRID:WB-STRAIN:WBStrain00062925 Copy
http://www.wormbase.org/db/get?name=WBStrain00062928
Source Database: WormBase (WB)
Affected Genes: WBGene00000396(cdh-4)
Genomic Alteration: WBGene00000396(cdh-4)
Availability: unknown
Source References: EMPTY
Synonyms: cdh-4(syb4476[cdh-4::SL2::GFP::H2B]) III.
Notes: Made_by: SUNY Biotech|"SL2::GFP::H2B tag inserted at C-terminus of endogenous cdh-4 locus."
Proper citation: RRID:WB-STRAIN:WBStrain00062928 Copy
http://www.wormbase.org/db/get?name=WBStrain00062880
Source Database: WormBase (WB)
Affected Genes: WBGene00306126(cone-1)
Genomic Alteration: WBGene00306126(cone-1)
Availability: unknown
Source References: EMPTY
Synonyms: cone-1(ot1502[GFP::H2B::SL2::cone-1]) III.
Notes: GFP::H2B tag with SL2 inserted at N-terminus of endogenous cone-1 locus. Ubiquitous nuclear green at all stages (as early as 2-cell). GFP signal is very bright compared to C-terminal tag in OH19215. Please contact Oliver Hobert prior to publishing work using this strain.|"Made_by: Michael Cesar"
Proper citation: RRID:WB-STRAIN:WBStrain00062880 Copy
http://www.wormbase.org/db/get?name=WBStrain00062881
Source Database: WormBase (WB)
Affected Genes: WBGene00001135(eat-4)
Genomic Alteration: WBGene00001135(eat-4)
Availability: unknown
Source References: EMPTY
Synonyms: Cbr-eat-4(ot1507[Cbr-eat-4::SL2::mScarlet3::H2B]) III.
Notes: Made_by: Itai Toker|"SL2::mScarlet3::H2B tag inserted before STOP codon of endogenous Cbr-eat-4 locus using CRISPR/Cas9. Generated in C. briggsae AF16 background. Reference: Toker IA, et al. bioRxiv 2024.11.23.624988; doi: https:"
Proper citation: RRID:WB-STRAIN:WBStrain00062881 Copy
http://www.wormbase.org/db/get?name=WBStrain00062885
Source Database: WormBase (WB)
Affected Genes: WBGene00001135(eat-4)
Genomic Alteration: WBGene00001135(eat-4)
Availability: unknown
Source References: EMPTY
Synonyms: Ctr-eat-4(ot1512[Ctr-eat-4::SL2::mScarlet3::H2B]) III.
Notes: Made_by: Itai Toker|"SL2::mScarlet3::H2B tag inserted before STOP codon of endogenous Ctr-eat-4 locus using CRISPR/Cas9. Generated in C. tropicalis NIC203 background. Reference: Toker IA, et al. bioRxiv 2024.11.23.624988; doi: https:"
Proper citation: RRID:WB-STRAIN:WBStrain00062885 Copy
http://www.wormbase.org/db/get?name=WBStrain00062882
Source Database: WormBase (WB)
Affected Genes: WBGene00010306(golg-4)
Genomic Alteration: WBGene00010306(golg-4)
Availability: unknown
Source References: EMPTY
Synonyms: golg-4(ot1508[GFP::golg-4]) III.
Notes: GFP tag inserted into endogenous golg-4 locus via CRISPR/Cas9 engineering. Reference: Cao WX, et al. (2024). bioRxiv: 2024.2006.2011.598534. https:|"Made_by: Wendy Cao (Hobert Lab)"
Proper citation: RRID:WB-STRAIN:WBStrain00062882 Copy
http://www.wormbase.org/db/get?name=WBStrain00062883
Source Database: WormBase (WB)
Affected Genes: WBGene00010306(golg-4)
Genomic Alteration: WBGene00010306(golg-4)
Availability: unknown
Source References: EMPTY
Synonyms: golg-4(ot1509[mScarlet3::golg-4]) III.
Notes: Made_by: Wendy Cao (Hobert Lab)|"mScarlet3 tag inserted into endogenous golg-4 locus via CRISPR/Cas9 engineering. Reference: Cao WX, et al. (2024). bioRxiv: 2024.2006.2011.598534. https:"
Proper citation: RRID:WB-STRAIN:WBStrain00062883 Copy
http://www.wormbase.org/db/get?name=WBStrain00062888
Source Database: WormBase (WB)
Affected Genes: WBGene00000464(ceh-44)
Genomic Alteration: WBGene00000464(ceh-44)
Availability: unknown
Source References: EMPTY
Synonyms: ceh-44(ot1515[*ot1015[ceh-44::gfp]]) III.
Notes: Made_by: Michael Cesar|"ot1015 is a GFP tag inserted at the C-terminus of the endogenous ceh-44 locus by CRISPR. ot1434 is a deletion removing exons 5-7 from the endogenously-tagged ceh-44 locus. No pan-neuronal nuclear GFP expression. Please contact Oliver Hobert prior to publishing work using this strain."
Proper citation: RRID:WB-STRAIN:WBStrain00062888 Copy
http://www.wormbase.org/db/get?name=WBStrain00062889
Source Database: WormBase (WB)
Affected Genes: WBGene00000912(daf-16)
Genomic Alteration: WBGene00000912(daf-16)
Availability: unknown
Source References: EMPTY
Synonyms: daf-16(ot853[daf-16::mNG::AID]) I; otSi2 II.
Notes: otSi2 [ges-1p::TIR1(F79G)::mRuby::unc-54 3'UTR + Cbr-unc-119(+) *ieSi61] II. Intestine-specific TIR1 sequence in ieSi61 allele was edited to TIR1(F79G) using CRISPR/Cas9 to make it compatible with AID2. [TCC GTC GAG CTC AAG GGA AAG CCA CAC TTC] edited to [AGT GTC GAA TTG AAG GGA AAG CCA CAC GGA]. This strain can be used to deplete DAF-16 specifically from the intestine with the modified auxin 5-Ph-IAA. Reference: Sural S, et al. bioRxiv 2025.01.06.631508; doi: https:
Proper citation: RRID:WB-STRAIN:WBStrain00062889 Copy
http://www.wormbase.org/db/get?name=WBStrain00062886
Source Database: WormBase (WB)
Affected Genes: WBGene00006756(unc-17)
Genomic Alteration: WBGene00006756(unc-17)
Availability: unknown
Source References: EMPTY
Synonyms: Ctr-unc-17(ot1513[Ctr-unc-17::T2A::mScarlet3::H2B]) IV.
Notes: Made_by: Itai Toker|"T2A::mScarlet3::H2B tag inserted before STOP codon of endogenous Ctr-unc-17 locus using CRISPR/Cas9. Generated in C. tropicalis NIC203 background. Reference: Toker IA, et al. bioRxiv 2024.11.23.624988; doi: https:"
Proper citation: RRID:WB-STRAIN:WBStrain00062886 Copy
http://www.wormbase.org/db/get?name=WBStrain00062920
Source Database: WormBase (WB)
Affected Genes: WBGene00001072(dpy-10)|WBGene00004416(rpl-5)
Genomic Alteration: WBGene00001072(dpy-10), WBGene00004416(rpl-5)
Availability: unknown
Source References: EMPTY
Synonyms: rpl-5(cc5998)/mIn1 [dpy-10(e128) mIs14] II.
Notes: Balancer recombination happens frequently at 23-25C, strain must be maintained at 16-20C. Homozygous lethal mutation balanced by Dpy- and myo-2p::GFP-marked inversion. Heterozygotes are wild-type with pharyngeal GFP signal, and segregate wild-type GFP+, Dpy bright GFP+ (mIn1 homozygotes), and non-GFP rpl-5(cc5998) homozygotes. Pick wild-type GFP+ to maintain. cc5998 is an engineered mutation creating an early stop (A166*). Presumptive rpl-5 null. Heterozygous rpl-5(cc5998)/mIn1 animals are delayed in development. Check for proper segregation of progeny. Reference: Cenik ES, et al. Dev Cell. 2019 Mar 25;48(6):811-826.e6. doi: 10.1016/j.devcel.2019.01.019. PMID: 30799226.|"Made_by: Elif Sarinay Cenik/ Agustian Surya"
Proper citation: RRID:WB-STRAIN:WBStrain00062920 Copy
http://www.wormbase.org/db/get?name=WBStrain00062914
Source Database: WormBase (WB)
Affected Genes: WBGene00004267(rab-3)
Genomic Alteration: WBGene00004267(rab-3)
Availability: unknown
Source References: EMPTY
Synonyms: jpnIs20 I; rab-3(jpn61[7xGFP11::rab-3]) II.
Notes: jpnIs20 [itr-1p::GFP1-10 + odr-1p::DsRed] I. 7xGFP tag was inserted into the N-terminal of the endogenous rab-3 locus. Expression in DA9 synapses can be observed. Generated in N2 background.|"Made_by: Taisei Watanabe"
Proper citation: RRID:WB-STRAIN:WBStrain00062914 Copy
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