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Integrated Animals is a virtual database currently indexing available animal strains and mutants from: AGSC (Ambystoma), BCBC (mice), BDSC (flies), European Xenopus Resource Center (frog), The National Xenopus Resource (frog), Xenopus Express (frog), CWRU Cystic Fibrosis Mouse Models (mice), DGGR (flies), FlyBase (flies), IMSR (mice), MGI (mice), MMRRC (mice), NSRRC (pig), RGD (rats), Sperm Stem Cell Libraries for Biological Research (rats), Tetrahymena Stock Center (Tetrahymena), WormBase (worms), XGSC (Xiphophorus), ZFIN (zebrafish), and ZIRC (zebrafish). Note, the IMSR data is linked, but users may need to re-execute the search if the top mouse is not returned properly.
Note: BCBC is no longer in service, so the links may not be functional.
http://www.wormbase.org/db/get?name=WBStrain00062190
Source Database: WormBase (WB)
Availability: unknown
Source References: PMID:39392750
Synonyms: daf-2(e1370) aak-1(tm1944)III; tbc-7(rr166) aak-2(ok524)X; rrEx976[NSM-specific tph-1p::gfp::rab-7; rol-6] line 1
Notes: EMPTY
Proper citation: RRID:WB-STRAIN:WBStrain00062190 Copy
http://www.wormbase.org/db/get?name=WBStrain00062191
Source Database: WormBase (WB)
Availability: unknown
Source References: PMID:39392750
Synonyms: daf-2(e1370) aak-1(tm1944)III; tbc-7(rr166) aak-2(ok524)X; rrEx977[ADF-specific srh-142p::gfp::rab-7; rol-6] line 1
Notes: EMPTY
Proper citation: RRID:WB-STRAIN:WBStrain00062191 Copy
http://www.wormbase.org/db/get?name=WBStrain00062182
Source Database: WormBase (WB)
Availability: unknown
Source References: PMID:39392750
Synonyms: ijmSi31[mex-5p::mCherry::his-11::tbb-2 3'UTR] II; daf-2(e1370)III; rrIs67[rgef-1p::HA::gfp::rab-7::rab-7 3'UTR + unc-119(+)]IV
Notes: EMPTY
Proper citation: RRID:WB-STRAIN:WBStrain00062182 Copy
http://www.wormbase.org/db/get?name=WBStrain00062221
Source Database: WormBase (WB)
Affected Genes: WBGene00003001(lin-12)
Genomic Alteration: WBGene00003001(lin-12)
Availability: unknown
Source References: EMPTY
Synonyms: lin-12(ljf31[lin-12::mNeonGreen[C1]::3xFLAG]) III.
Notes: Made_by: Ariel Pani|"mNG and 3xFLAG tags fused to the C-terminal end of the intracellular domain of the endogenous lin-12 locus using a 9 amino acid flexible linker. Reference: Pani AM, et al. A new toolkit to visualize and perturb endogenous LIN-12/Notch signaling in C. elegans. MicroPubl Biol. 2022 Jul 28;2022:10.17912/micropub.biology.000603. doi: 10.17912/micropub.biology.000603. PMID: 35966394."
Proper citation: RRID:WB-STRAIN:WBStrain00062221 Copy
http://www.wormbase.org/db/get?name=WBStrain00062225
Source Database: WormBase (WB)
Affected Genes: WBGene00022172(cosa-1)
Genomic Alteration: WBGene00022172(cosa-1)
Availability: unknown
Source References: EMPTY
Synonyms: cosa-1(viz154[GFP::cosa-1])III.
Notes: GFP tag inserted at N-terminus of endogenous cosa-1 locus. Expressed primarily in both hermaphrodite and male gonad. Reference: Ortega J, et al. Sci. Adv.10,eadp0466(2024).DOI:10.1126/sciadv.adp0466 https:|"Made_by: Jacob Ortega"
Proper citation: RRID:WB-STRAIN:WBStrain00062225 Copy
http://www.wormbase.org/db/get?name=WBStrain00062223
Source Database: WormBase (WB)
Affected Genes: WBGene00004178(prg-1)
Genomic Alteration: WBGene00004178(prg-1)
Availability: unknown
Source References: EMPTY
Synonyms: prg-1(viz142[V5::mCherry::GSIGSLRSI::prg-1] viz146[PAZ deletion]) I.
Notes: 282bp deletion (247aa-345aa) in PAZ domain of endogenously-tagged prg-1 locus. V5 epitope and mCherry tags with a flexible linker inserted after the first 18 nt of the coding sequence of endogneous prg-1 locus. mCherry tagged PRG-1 primarily expressed and localized in both hermaphrodite and male gonad. Reference: Ortega J, et al. Sci. Adv.10,eadp0466(2024).DOI:10.1126/sciadv.adp0466 https:|"Made_by: Jacob Ortega"
Proper citation: RRID:WB-STRAIN:WBStrain00062223 Copy
http://www.wormbase.org/db/get?name=WBStrain00062228
Source Database: WormBase (WB)
Affected Genes: WBGene00003607(nhr-8)
Genomic Alteration: WBGene00003607(nhr-8)
Availability: unknown
Source References: EMPTY
Synonyms: nhr-8(ok186) IV; acEx187.
Notes: acEx187 [vha-6p::nhr-8::SL2::GFP + rol-6(su1006)]. Pick Rollers to maintain (GFP expression in intestine is easy to see and might be easier to score than Rol). Intestinal rescue of nhr-8(ok186) mutants. Reference: Otarigho B & Aballay A. 2020. iScience. 2020 May 22;23(5):101068. doi: 10.1016/j.isci.2020.101068. PMID: 32361270.|"Made_by: Benson Otarigho"
Proper citation: RRID:WB-STRAIN:WBStrain00062228 Copy
http://www.wormbase.org/db/get?name=WBStrain00062180
Source Database: WormBase (WB)
Availability: unknown
Source References: PMID:39392750
Synonyms: daf-2(e1370)III; rrEx958[tsp-7p::tsp-7::gfp::tsp-7 3'UTR; rol-6] line 1
Notes: EMPTY
Proper citation: RRID:WB-STRAIN:WBStrain00062180 Copy
http://www.wormbase.org/db/get?name=WBStrain00062172
Source Database: WormBase (WB)
Availability: unknown
Source References: PMID:39392750
Synonyms: daf-2(e1370) aak-1(tm1944)III; tbc-7(rr166) aak-2(ok524)X; rrEX920[tph-1p::tbc-7; rol-6] line 1
Notes: EMPTY
Proper citation: RRID:WB-STRAIN:WBStrain00062172 Copy
http://www.wormbase.org/db/get?name=WBStrain00062171
Source Database: WormBase (WB)
Availability: unknown
Source References: PMID:39392750
Synonyms: daf-7(e1372)III; rrEx917[rgef-1::HA::gfp::rab-7; sur-5::NeoR; rgef-1::ollas::tsp-7; rgef-1::3xFLAG::mKate; rol-6] line 1
Notes: EMPTY
Proper citation: RRID:WB-STRAIN:WBStrain00062171 Copy
http://www.wormbase.org/db/get?name=WBStrain00062210
Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: unknown
Source References: EMPTY
Synonyms: juSi164 unc-119(ed3) III; wtfIs263.
Notes: juSi164 [mex-5p::HIS-72::miniSOG + Cbr-unc-119(+)] III. wtfIs263 [rab-3p::AI::ChR2(H134R)::unc-54 3'UTR + rab-3p::AI::Voltron::unc-54 3'UTR + rab-3p::his-24::tagBFP::unc-54 3'UTR]. Keep plates covered to avoid unnecessary exposure to light. Pan-neuronal expression of ChR2 (H134R) along with Voltron volatage indicator and nuclear-localized tagBFP. Reporter construct contains an artificial intron (AI). Reference: Sharma AK, et al. Genetics 2024 May 11:iyae077. doi: 10.1093/genetics/iyae077 PMID: 38733622.
Proper citation: RRID:WB-STRAIN:WBStrain00062210 Copy
http://www.wormbase.org/db/get?name=WBStrain00062175
Source Database: WormBase (WB)
Availability: unknown
Source References: PMID:39392750
Synonyms: daf-2(e1370)III; mkcIs13[sun-1p::rde-1::sun-1 3'UTR + unc-119(+)]II; rde-1(mck36)V; rrEx931[rgef-1p::gfp::rab-7; rol-6] line 1
Notes: EMPTY
Proper citation: RRID:WB-STRAIN:WBStrain00062175 Copy
http://www.wormbase.org/db/get?name=WBStrain00062213
Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: unknown
Source References: EMPTY
Synonyms: juSi164 unc-119(ed3) III; wtfIs335.
Notes: juSi164 [mex-5p::HIS-72::miniSOG + Cbr-unc-119(+)] III. wtfIs335 [5xQUAS+(delta)pes-10p::AI::eTsChR::unc-54 3'UTR + rab-3p::AI::QF+hGR::SL2::tagBFP::unc-54 3'UTR + rab-3p::his-24::tagRFP::unc-54 3'UTR + rab-3p::his-24::GCaMP6s::unc-54 3'UTR]. Keep plates covered to avoid unnecessary exposure to light. Pan-neuronal eTsChR on activation using dex treatment via QF+hGR. Worms also express calcium sensing fluorescence protein- GCaMP6s in nuclei of each neurons. Reporter construct contains an artificial intron (AI). Reference: Sharma AK, et al. Genetics 2024 May 11:iyae077. doi: 10.1093/genetics/iyae077 PMID: 38733622.
Proper citation: RRID:WB-STRAIN:WBStrain00062213 Copy
http://www.wormbase.org/db/get?name=WBStrain00062214
Source Database: WormBase (WB)
Availability: unknown
Source References: EMPTY
Synonyms: wtfEx478.
Notes: wtfEx478 [rab-3p::AI::lite-1G::SL2::tagBFP::unc-54 3'UTR + unc-122p::GFP]. Pick GFP+ animals to maintain. Worms express purple/violet light-sensitive optogenetic protein LITE-1 pan-neuronallly and nuclear-localized blue fluorescent protein tagBFP via SL2 trans-slpicing regulatory sequence. Worms also express GFP in coelomocytes. Reporter construct contains an artificial intron (AI). Reference: Sharma AK, et al. Genetics 2024 May 11:iyae077. doi: 10.1093/genetics/iyae077 PMID: 38733622.
Proper citation: RRID:WB-STRAIN:WBStrain00062214 Copy
http://www.wormbase.org/db/get?name=WBStrain00062211
Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: unknown
Source References: EMPTY
Synonyms: juSi164 unc-119(ed3) III; wtfEx296.
Notes: juSi164 [mex-5p::HIS-72::miniSOG + Cbr-unc-119(+)] III. wtfEx296 [rab-3p::AI::gur-3G::unc-54 3'UTR + rab-3p::AI::prdx-2G::SL2::his-24::tagRFP::unc-54 3'UTR + rab-3p::his-24::GCaMP6s::unc-54 3'UTR]. Pick RFP+ to maintain. Keep plates covered to avoid unnecessary exposure to light. Worms expressing a purple light-sensitive optogenetic protein system: pan-neuronal expression of GUR-3 and PRDX-2 with nuclear-localized tagRFP and GCaMP6s. Reporter construct contains an artificial intron (AI). Reference: Sharma AK, et al. Genetics 2024 May 11:iyae077. doi: 10.1093/genetics/iyae077 PMID: 38733622.
Proper citation: RRID:WB-STRAIN:WBStrain00062211 Copy
http://www.wormbase.org/db/get?name=WBStrain00062179
Source Database: WormBase (WB)
Availability: unknown
Source References: PMID:39392750
Synonyms: daf-2(e1370)III; rrEx957[rgef-1p::mKate::T2A::gfp::rab-7; rol-6] line 1
Notes: EMPTY
Proper citation: RRID:WB-STRAIN:WBStrain00062179 Copy
http://www.wormbase.org/db/get?name=WBStrain00062216
Source Database: WormBase (WB)
Availability: unknown
Source References: EMPTY
Synonyms: wtfIs491.
Notes: Made_by: Anuj Sharma & Kevin Chen|"wtfIs491 [inx-1p::twk-18(gf)::mCherry + unc-122p::RFP]. AIB(-) activated potassium channel. Expression of twk-18 gain-of-function mutant in AIB neurons causes permanent inhibition. RFP expression in coelomocytes. Reference: Chen KS, et al. Olfactory learning alters navigation strategies and behavioral variability in C. elegans. ArXiv, Feb 23:arXiv:2311.07117v2. PMID: 38013890."
Proper citation: RRID:WB-STRAIN:WBStrain00062216 Copy
http://www.wormbase.org/db/get?name=WBStrain00062208
Source Database: WormBase (WB)
Availability: unknown
Source References: EMPTY
Synonyms: wtfIs145.
Notes: wtfIs145 [rab-3p::his-24::GCaMP6s::unc-54 3'UTR + pha-1(+)]. Pan-neuronal expression of nuclear-localized GCaMP6s. Reference: Sharma AK, et al. Genetics 2024 May 11:iyae077. doi: 10.1093/genetics/iyae077 PMID: 38733622.
Proper citation: RRID:WB-STRAIN:WBStrain00062208 Copy
http://www.wormbase.org/db/get?name=WBStrain00062209
Source Database: WormBase (WB)
Availability: unknown
Source References: EMPTY
Synonyms: otIs669 V.
Notes: Derived by out-crossing parental strain OH15262 an additional six times to N2. Out-crossed strain AML318 seems healthier than parental strain when maintaining long-term under normal conditions (AML observed an increase in male and sterile progeny in parental strain in successive generations.) otIs669 [UPN::NLS::TagRFP-T + acr-5::NLS::mTagBFP2::H2B + flp-1::NLS::mTagBFP2::H2B + flp-6::NLS::mTagBFP2::H2B + flp-18::NLS::mTagBFP2::H2B + flp-19::NLS::mTagBFP2::H2B + flp-26::NLS::mTagBFP2::H2B + gcy-18::NLS::mTagBFP2::H2B + ggr-3::NLS::mTagBFP2::H2B + lim-4::NLS::mTagBFP2::H2B + pdfr-1::NLS::mTagBFP2::H2B + srab-20::NLS::mTagBFP2::H2B + unc-25::NLS::mTagBFP2::H2B + cho-1::NLS::CyOFP1::H2B + flp-13::NLS::CyOFP1::H2B + flp-20::NLS::CyOFP1::H2B + gcy-36::NLS::CyOFP1::H2B + gpa-1::NLS::CyOFP1::H2B + nlp-12::NLS::CyOFP1::H2B + nmr-1::NLS::CyOFP1::H2B + ocr-1::NLS::CyOFP1::H2B + osm-9::NLS::CyOFP1::H2B + srh-79::NLS::CyOFP1::H2B + sri-1::NLS::CyOFP1::H2B + srsx-3::NLS::CyOFP1::H2B + unc-8::NLS::CyOFP1::H2B + acr-2::NLS::mNeptune2.5 + ceh-2::NLS::mNeptune2.5 + dat-1::NLS::mNeptune2.5 + dhc-3::NLS::mNeptune2.5 + eat-4::NLS::mNeptune2.5 + flp-3::NLS::mNeptune2.5 + gcy-35::NLS::mNeptune2.5 + glr-1::NLS::mNeptune2.5 + gcy-21::NLS::CyOFP1::H2B::T2A::NLS::mTagBFP2::H2B + klp-6::NLS::mNeptune2.5::T2A::NLS::CyOFP1::H2B + lim-6::NLS::mNeptune2.5::T2A::NLS::CyOFP1::H2B + mbr-1::NLS::mNeptune2.5::T2A::NLS::mTagBFP2::H2B + mec-3::NLS::CyOFP1::H2B::T2A::NLS::mTagBFP2::H2B + odr-1::NLS::mNeptune2.5::T2A::NLS::mTagBFP2::H2B + srab-20::NLS::mNeptune2.5::T2A::NLS::mTagBFP2::H2B] V. UPN (Ultra Pan-Neuronal) promoter contains four short pan-neuronal promoters fused together (unc-11::rgef-1::ehs-1::ric-19). NeuroPAL (Neuronal Polychromatic Atlas of Landmarks) transgene used to resolve unique neural identities in whole-brain images. Reference: Yemini E, et al. Cell. 2021 Jan 7;184(1):272-288.e11. PMID: 33378642.
Proper citation: RRID:WB-STRAIN:WBStrain00062209 Copy
http://www.wormbase.org/db/get?name=WBStrain00062161
Source Database: WormBase (WB)
Availability: unknown
Source References: PMID:39392750
Synonyms: rrIs62[pie-1p::his-15::gfp::3xmir-51::tbb-2 3UTR]II; unc-119(+)II; daf-2(e1370) aak-1(tm1944) unc-119(ed3)III; aak-2(ok524)X; oxEx1678
Notes: EMPTY
Proper citation: RRID:WB-STRAIN:WBStrain00062161 Copy
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