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Integrated Animals is a virtual database currently indexing available animal strains and mutants from: AGSC (Ambystoma), BCBC (mice), BDSC (flies), European Xenopus Resource Center (frog), The National Xenopus Resource (frog), Xenopus Express (frog), CWRU Cystic Fibrosis Mouse Models (mice), DGGR (flies), FlyBase (flies), IMSR (mice), MGI (mice), MMRRC (mice), NSRRC (pig), RGD (rats), Sperm Stem Cell Libraries for Biological Research (rats), Tetrahymena Stock Center (Tetrahymena), WormBase (worms), XGSC (Xiphophorus), ZFIN (zebrafish), and ZIRC (zebrafish). Note, the IMSR data is linked, but users may need to re-execute the search if the top mouse is not returned properly.
Note: BCBC is no longer in service, so the links may not be functional.
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=14398734
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: mutant
Availability: Live Animals (as of 2021-02-12)
Alternate IDs: RGD_14398734, 14398734, RRRC_857, RRRC_0857, RRRC_00857
Notes: The CRISPR system was used to created target insertion of iCre recombinase immediately after Adora2a gene, with P2A linker, of the embryos of BluHsd:LE. Rat Resource and Research Center
Proper citation: RRID:RRRC_00857 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=7245494
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: transgenic
Availability: Cryopreserved Sperm (as of 2019-02-05)
Alternate IDs: RGD_7245494, 7245494, RRRC_633, RRRC_0633, RRRC_00633
Notes: Strain carries a transgene expressing human TDP43 with the M337V mutation under control of a tTA-dependent promoter (TRE). When mated to a second transgenic strain (RRRC:632) that carries a tetracycline-controlled transactivator driven by the mouse choline acetyltransferase (Chat) promoter, the expression of mutant TDP43 in Chat-expressing motor neurons in the double transgenic rats can be induced by withdrawal of doxycycline. Rat Resource and Research Center
Proper citation: RRID:RRRC_00633 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=7245488
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: transgenic
Availability: Cryopreserved Sperm (as of 2019-02-05)
Alternate IDs: RGD_7245488, 7245488, RRRC_632, RRRC_0632, RRRC_00632
Notes: Rats express a mouse tetracycline-controlled transactivator (tTA) driven by the mouse choline acetyltransferase (Chat) promotor. When mated to a second transgenic strain (RRRC:00633) that carries a target gene (TDP43) under the regulation of a tetracycline response element (TRE), the expression of TDP43 in Chat-expressing motor neurons in the double transgenic rats can be induced by withdrawal of doxycycline. Rat Resource and Research Center
Proper citation: RRID:RRRC_00632 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=153323320
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: inbred
Availability: Live Animals; Cryopreserved Embryo; Cryorecovery (as of 2023-10-25)
Alternate IDs: RGD_153323320, 153323320, RRRC_00173
Notes: Origin: as for MNR except selection was for high defecation response in the open field. To Harrington in 1965 at F25 and to NIH in 1964 at F18+ (Hansen et al 1982). Now is available at Rat Resource & Research Center Rat Resource and Research Center, RGD HRDP, contact HRDP
Proper citation: RRID:RRRC_00173 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=155641251
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: transgenic
Availability: Live Animals (as of 2022-11-04)
Alternate IDs: RGD_155641251, 155641251, RRRC_946, RRRC_0946, RRRC_00946
Notes: The human ACE2 gene was placed under control of the synthetic CAG promoter which allows ubiquitous expression of the gene. Based on droplet digital PCR analysis, the strain carries only 1 copy of the transgene. The integration site is unknown. These rats express the human ACE2 gene. The encoded protein is a functional receptor for the spike glycoprotein of several human coronaviruses including SARS-CoV-2, the causative agent of coronavirus disease-2019 (COVID-19). Rat Resource and Research Center
Proper citation: RRID:RRRC_00946 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=9588570
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: transgenic
Availability: Unknown
Alternate IDs: RGD_9588570, 9588570, RRRC_766, RRRC_0766, RRRC_00766
Notes: The transgene contains reporter rat expressing eGFP in cFos expressing cells Optogenetics and Transgenic Technology Core, Rat Resource and Research Center
Proper citation: RRID:RRRC_00766 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=9588572
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: transgenic
Availability: Unknown
Alternate IDs: RGD_9588572, 9588572, RRRC_730, RRRC_0730, RRRC_00730
Notes: The transgene contains BAC transgenic using rat DAT promoter to express Cre recombinase in dopaminergic neurons Optogenetics and Transgenic Technology Core, Rat Resource and Research Center
Proper citation: RRID:RRRC_00730 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=155641245
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: transgenic
Availability: Live Animals; Cryopreserved Embryo; Cryopreserved Sperm (as of 2023-12-13)
Alternate IDs: RGD_155641245, 155641245, RRRC_975, RRRC_0975, RRRC_00975
Notes: Targeted knock-in adding a T2A-iCre to the Oprm1 (mu opioid receptor) in this cre recombinase reporter SD rat Rat Resource and Research Center
Proper citation: RRID:RRRC_00975 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=1358303
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: transgenic
Availability: Unknown
Alternate IDs: RGD_1358303, 1358303, RRRC_645, RRRC_0645, RRRC_00645
Notes: This transgenic strain carries a mouse rhodopsin gene that bears a termination codon at residue 334, which encodes a C-terminal truncated opsin protein. Retinal Degeneration Rat Model Resource ,Rat Resource and Research Center
Proper citation: RRID:RRRC_00645 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=1358300
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: transgenic
Availability: Unknown
Alternate IDs: RGD_1358300, 1358300, RRRC_641, RRRC_0641, RRRC_00641
Notes: This transgenic strain carries a copy of mouse Rhodopsin gene with a proline to histidine substitution at codon 23 (c.68C>A). Retinal Degeneration Rat Model Resource ,Rat Resource and Research Center
Proper citation: RRID:RRRC_00641 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=155900757
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: mutant
Availability: Unknown (as of 2023-12-19)
Alternate IDs: RGD_155900757, 155900757, RRRC_985, RRRC_0985, RRRC_00985
Notes: Using CRISPR/Cas9 genomic engineering in rats via homologous end-joining in fertilized embryos, we have knocked'in a humanized CHRNA6 3'UTR in place of the natural CHRNA6 3'UTR of the Sprague Dawley rat line. This new genetically modified CHRNA6C123G humanized rat line carries a homozygous CC nucleotide modification at position 123 within the CHRNA6 gene 3'UTR. The laboratory has deposited these strains with the Rat Resource and Research Center
Proper citation: RRID:RRRC_00985 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=728193
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: outbred
Availability: Extinct
Alternate IDs: RGD_728193, 728193, RRRC_239, RRRC_0239, RRRC_00239
Notes: To N 1945 from Sprague Dawley, Inc. Colony closed since then. NIH Autoimmune Rat Model Repository and Development Center, Rat Resource and Research Center
Proper citation: RRID:RRRC_00239 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=13208224
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: mutant
Availability: Cryorecovery (as of 2025-08-29)
Alternate IDs: RGD_13208224, 13208224, RRRC_833, RRRC_0833, RRRC_00833
Notes: The CRISPR/Case9 knock-in rats have cre recombinase-dependent expression of Cas9 under the control of CAG promoter inserted to the rat ROSA26 locus. ROSA26 is a synonym for rat Thumpd3-as1 (RGD:6491660) and is used as an official symbol for rat strain nomenclature. Rat Resource and Research Center
Proper citation: RRID:RRRC_00833 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=7364940
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: mutant
Availability: Unknown
Alternate IDs: RGD_7364940, 7364940, RRRC_661, RRRC_0661, RRRC_00661
Notes: Backcrossed STOCK-Tp53tm1(EGFP-Pac)QlyRrrc with F344 using speed congenic approach to move mutation onto F344 genetic background. Rat Resource and Research Center
Proper citation: RRID:RRRC_00661 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=14398460
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: mutant
Availability: Unknown
Alternate IDs: RGD_14398460, 14398460, RRRC_840, RRRC_0840, RRRC_00840
Notes: Zinc Finger Nuclease (ZFN) was utilized to knockout rat CD40 function in the embryos of SS/JrHsd rats. The target sequence (CAGCACCGACACTGCgaactcAGTGCGTGGGGCTGCCGGG) introduced an 11 bp-deletion (CTGCGAACTCA) in the third exon of the Cd40 gene, resulted in a trucated protein. Rat Resource and Research Center
Proper citation: RRID:RRRC_00840 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=152999002
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: mutant
Availability: Unknown
Alternate IDs: RGD_152999002, 152999002, RRRC_961, RRRC_0961, RRRC_00961
Notes: Heterozygous KO of the Fxn gene obtained by targeting exon 4 with CRISPR/Cas9 system Rat Resource and Research Center
Proper citation: RRID:RRRC_00961 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=150521660
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: transgenic
Availability: Unknown
Alternate IDs: RGD_150521660, 150521660, RRRC_687, RRRC_0687, RRRC_00687
Notes: The transgene contains Cre recombinase reporter rat expressing mCherry driven by the EF1 alpha promoter. A Rrrc substrain available at Rat Resource and Research Center
Proper citation: RRID:RRRC_00687 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=13207341
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: congenic
Availability: Unknown
Alternate IDs: RGD_13207341, 13207341, RRRC_825, RRRC_0825, RRRC_00825
Notes: This congenic strain contains a fragment of chromosome 17 from the LH-Chr 17LN/Aek from Fanccrgdv551196202-C through rs107291522 transferred to the LH/MRrrcAek background. Rat Resource & Research Center
Proper citation: RRID:RRRC_00825 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=150521606
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: mutant
Availability: Unknown
Alternate IDs: RGD_150521606, 150521606, RRRC_880, RRRC_0880, RRRC_00880
Notes: CRISPR/Cas9 system was used to introduce a 22-bp deletion at the sgRNA2 site of exon 2 in the rat Lrp5 gene of Crl:SD embryos. Rat Resource and Research Center
Proper citation: RRID:RRRC_00880 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=11087551
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: mutant
Availability: Unknown
Alternate IDs: RGD_11087551, 11087551, RRRC_769, RRRC_0769, RRRC_00769
Notes: Zinc finger nuclease mediated 7bp deletion within exon 2 of the Il15 gene, resulting in a frameshift and premature stop codon. Rat Resource and Research Center
Proper citation: RRID:RRRC_00769 Copy
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