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Integrated Animals is a virtual database currently indexing available animal strains and mutants from: AGSC (Ambystoma), BCBC (mice), BDSC (flies), European Xenopus Resource Center (frog), The National Xenopus Resource (frog), Xenopus Express (frog), CWRU Cystic Fibrosis Mouse Models (mice), DGGR (flies), FlyBase (flies), IMSR (mice), MGI (mice), MMRRC (mice), NSRRC (pig), RGD (rats), Sperm Stem Cell Libraries for Biological Research (rats), Tetrahymena Stock Center (Tetrahymena), WormBase (worms), XGSC (Xiphophorus), ZFIN (zebrafish), and ZIRC (zebrafish). Note, the IMSR data is linked, but users may need to re-execute the search if the top mouse is not returned properly.
Note: BCBC is no longer in service, so the links may not be functional.
| Organism Name | Proper Citation | Species | Synonyms |
Notes |
Phenotype | Affected Gene | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
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∆PDD2-som-Bc4 Resource Report Resource Website |
RRID:TSC_SD01323 | Tetrahymena thermophila | Progeny of B2086XCU428 transformation. Somatic KO of PDD2 gene. Mates with CU427, CU428, ∆PDD2-som-BC1, BC3 From the Gorovsky lab, University of Rochester. This strain has been cataloged by the Stock Center but not thawed. | PDD2 (TTHERM_00283530) | Macronucleus: PDD2 with neo2 replacing the 5’ part of coding | SD01323 | (pdd2[∆?::neo2], ?) | TSC, Tetrahymena Stock Center | TSC | PMID:10805754 PMID:10557212 |
TSC | 2026-10-10 05:05:52 | 0 | ||||
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∆CnjB #1 Resource Report Resource Website |
RRID:TSC_SD01845 | Tetrahymena thermophila | somatic knock-outs of CnjB obtained by mating heterozygous CnjB KO heterokaryon with WT then assorted to complete KO in mac; mate with ∆CnjB #3 From the Gorovsky lab, University of Rochester. This strain has been cataloged by the Stock Center but not thawed. | cnjB (TTHERM_01091290) | Micronucleus: Part of CnjB coding replaced with neo3 Macronucleus: Part of CnjB coding replaced with neo3, completely assorted | SD01845 | CnjB/cnjB[∆?::neo3] (cnjB[∆?::neo3] CnjB:neo3, fully assorted; pm-r) | TSC, Tetrahymena Stock Center | TSC | PMID:19596782 | TSC | 2026-10-10 05:05:51 | 0 | ||||
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F8∆CnjB Resource Report Resource Website |
RRID:TSC_SD02780 | Tetrahymena thermophila | Heterozygous heterkaryon for ∆CnjB. Mates with Tomoko’s ∆CnjB 2-1. From the Gorovsky lab, University of Rochester. This strain has been cataloged by the Stock Center but not thawed. | CnjB (TTHERM_01091290) | Micronucleus: CnjB has part of coding replaced with neo3 | SD02780 | CnjB/cnjB[∆?::neo3] (?) | TSC, Tetrahymena Stock Center | TSC | PMID:19596782 | TSC | 2026-10-10 05:05:52 | 0 | ||||
|
doubleKO 5’cd eri1+ twi1 C1 Resource Report Resource Website |
RRID:TSC_SD02025 | Tetrahymena thermophila | Eri1 KO construct was shot into twi1 KO homozygous homokaryon (Neo3 gene is lost in mac, strain is pm-s). From the Gorovsky lab, University of Rochester. This strain has been cataloged by the Stock Center but not thawed. | ERI1 (TTHERM_00501020) | Micronucleus: TWI1 KO Macronucleus: twi1 kO and ERI1 KO | SD02025 | twi1[∆?::neo3]/twi1[∆?::neo3] (twi1[∆?::neo3]; eri1[∆?::neo3]; same as ∆Twi1, ?) | TSC, Tetrahymena Stock Center | TSC | TSC | 2026-10-10 05:05:51 | 0 | |||||
|
SB2401H Resource Report Resource Website |
RRID:TSC_SD01297 | Tetrahymena thermophila | This strain must be crossed to A* for two rounds and cy-r progeny selected to generate the meiotic segregant panel member which is cy-r, mp-r, pm-s, mat3 Submitted by Eduardo Orias, University of California, Santa Barbara | SD01297 | chx1-1/chx1-1; mpr1-1/mpr1-1; PMR1[C3]/PMR1[C3]; MAT3/MAT3 (CHX1[C3]; cy-s, ?) | TSC, Tetrahymena Stock Center | TSC | PMID:8725229 PMID:8601476 |
TSC | 2026-10-10 05:05:51 | 0 | ||||||
|
8596-2 Resource Report Resource Website |
RRID:TSC_SD03115 | Tetrahymena thermophila | Collected by Paul Doerder on 7/22/1994 from the pond designated SG29 in PA (latitude 41.73, longitude -79.23) Presence of micronucleus not determined. | SD03115 | (V) | TSC, Tetrahymena Stock Center | TSC | PMID:25973525 | TSC | 2026-10-10 05:05:52 | 0 | ||||||
|
DRH1 s ∆ C7-5D Resource Report Resource Website |
RRID:TSC_SD01850 | Tetrahymena thermophila | Somatic KO of DRH1 with neo3 KO2 construct. 5’ end of coding removed. Bad maters so not used See Jody DRH1 logbook Gene is expressed at low level in starve and log, peak expression at 4 hr of conjugation. Somatic KO is complete, when mated they arrest after Meiosis II. Homozygous homokaryons do not grow well. From the Gorovsky lab, University of Rochester. This strain has been cataloged by the Stock Center but not thawed. | DRH1 (TTHERM_00190830) | Macronucleus: Neo3 cassette replaces part of 5’ end of coding | SD01850 | in CU427, chx1-1/chx1-1 (drh1[∆?::neo3]; DRH1 gene 5’ end of coding replaced with Neo3 ,pm-r up to 700ug/ml pm with Cd., VI) | TSC, Tetrahymena Stock Center | TSC | TSC | 2026-10-10 05:05:51 | 0 | |||||
|
B1868 VII Resource Report Resource Website |
RRID:TSC_SD01619 | Tetrahymena thermophila | Inbred B clones were originally generated in studies on mating-type determination; B1868 = 18th generation of inbreeding, most recent inbreeding cross in 1968. Submitted by Joseph Frankel, University of Iowa | SD01619 | mat1-2/mat1-2; serH-3/serH-3 (mat1-2; serH-3, VI) | TSC, Tetrahymena Stock Center | TSC | PMID:17248630 PMID:1395139 PMID:17247884 PMID:11973302 |
TSC | 2026-10-10 05:05:52 | 0 | ||||||
|
C-C8-V5-PP36 Resource Report Resource Website |
RRID:TSC_SD02271 | Tetrahymena thermophila | somatic mac transformation of CU428 with construct of PP36 (Protein phosphatase 36 kD MW, predicted TTHERM_00238830) V5 tag after ATG, with neo3 in reverse orientation -200 bases upstream of ATG. Localizes to nucleoli, not studied further. Incomplete replacement, pushed to 3mg/ml pm with 0.5ug/ml Cd. From the Gorovsky lab, University of Rochester. This strain has been cataloged by the Stock Center but not thawed. | TTHERM_00238830 | Macronucleus: V5 tagged PP36 protein | SD02271 | mpr1-1/mpr1-1 (pm-r, VII) | TSC, Tetrahymena Stock Center | TSC | PMID:22426537 | TSC | 2026-10-10 05:05:51 | 0 | ||||
|
HTA1-D1M01 Resource Report Resource Website |
RRID:TSC_SD02395 | Tetrahymena thermophila | G4B1G10A x G4B3C1A. wt HTA1 (pXL53) rescue ∆HTA1∆HTA2 double knockout heterokaryon. Assort to pm-s. Mates with HTA1-D1A01, D2B01, D3E01 From the Gorovsky lab, University of Rochester. This strain has been cataloged by the Stock Center but not thawed. | HTA1 (TTHERM_00790790) + HTA2 (TTHERM_00316500) | Micronucleus: Neo 2 knockout of HTAX and HTA1 genes Macronucleus: WT HTAX | SD02395 | hta1[∆::neo2]/hta1[∆::neo2]; hta2[∆::neo2]/ hta2[∆::neo2]; CHX1/CHX1;mpr1?/mpr1? (HTA1 (now HTAX) is WT but HTA2 (now HTA1) has neo2, ?) | TSC, Tetrahymena Stock Center | TSC | PMID:11430834 PMID:12665578 |
TSC | 2026-10-10 05:05:52 | 0 | ||||
|
IA336 Resource Report Resource Website |
RRID:TSC_SD01462 | Tetrahymena thermophila | Conical shape; expression slightly more pronounced at 39° than at 28° C. Division products are equal in size. Very similar shape to the much more studied con1-1 mutant (J. Exp. Zool. 192: 237-258), but differs in that division products are approximately equal in size, indicating that conical shape does not per se lead to smaller posterior daughter cells. Submitted by Joseph Frankel, University of Iowa | CON2 (conical2) | SD01462 | con2-1/con2-1 (con2-1, V) | TSC, Tetrahymena Stock Center | TSC | TSC | 2026-10-10 05:05:52 | 0 | ||||||
|
IA110 Resource Report Resource Website |
RRID:TSC_SD01586 | Tetrahymena thermophila | A relatively weakly expressed mutant allele of cdaA, in which cytokinesis is only partially arrested at 39oC; it is the only cdaA mutant allele derived from EMS mutagenesis. Submitted by Joseph Frankel, University of Iowa | CDAA (cell division arrest A) | SD01586 | cdaA-3/cdaA-3 (cdaA-3; cdaA, III) | TSC, Tetrahymena Stock Center | TSC | TSC | 2026-10-10 05:05:52 | 0 | ||||||
|
VI005 Resource Report Resource Website |
RRID:TSC_SD01740 | Tetrahymena thermophila | The knockout also deletes 838bp of the 5' flanking region and introduces a frameshift mutation. The knockout has been confirmed by paromomycin resistance, but macronuclear allele homozygosity has not been verified. The neo4-KanR2 knockout cassette was generated by cloning fragments of the pNeo4 plasmid's neo4 cassette and the pUC4K plasmid's KanR2 cassette. The KanR2 gene was used for E. coli transformation and is not a selectable marker in Tetrahymena. Submitted by Robert Coyne, J. Craig Venter Institute | LSD2 (TTHERM_00600670) | Micronucleus: PAR1 gene partially replaced by neo4-KanR2 cassette. Macronucleus: LSD2 gene partially replaced by neo4-KanR2 cassette. | SD01740 | (LSD2/lsd2-1[Δ1-302(::neo4, KanR2)]; pm-r, II) | TSC, Tetrahymena Stock Center | TSC | TSC | 2026-10-10 05:05:53 | 0 | |||||
|
PPG1∆4-3/1 Resource Report Resource Website |
RRID:TSC_SD02034 | Tetrahymena thermophila | Possible polyglycine protein gene was knocked out with neo3 cassette. This is a PPG1 KO heterokaryon with homozygous mic KO and mac assorted to wt.This strain can mate with PPG1∆1 and PPG1∆3 cells. Final name of gene is PGP1 when published. From the Gorovsky lab, University of Rochester. This strain has been cataloged by the Stock Center but not thawed. | PGP1 | Micronucleus: neo3 into PGP1 locus | SD02034 | pgp1[∆?::neo3]/pgp1[∆?::neo3] (VI) | TSC, Tetrahymena Stock Center | TSC | PMID:17189490 | TSC | 2026-10-10 05:05:53 | 0 | ||||
|
IA244 Resource Report Resource Website |
RRID:TSC_SD01222 | Tetrahymena thermophila | Disorganized ciliary rows at 39-40 degrees C. Straightforward t.s. expression of disorganized phenotype,cell division normal. Submitted by Joseph Frankel, University of Iowa | DISD (disorganized-D) | SD01222 | disD-1/disD-1 (disD-1, IV) | TSC, Tetrahymena Stock Center | TSC | PMID:18658256 | TSC | 2026-10-10 05:05:52 | 0 | |||||
|
SAI 2 HA-9 Resource Report Resource Website |
RRID:TSC_SD02832 | Tetrahymena thermophila | Mac-DCL1 was completely replaced with DCL1-HA-neo3, CU428. DCL1 = SAI 2, the original name. From the Gorovsky lab, University of Rochester. This strain has been cataloged by the Stock Center but not thawed. | DCL1 (TTHERM_00284230) | Macronucleus: Mac-DCL1 was completely replaced with DCL1-HA- with neo3 in 3’ flanking region | SD02832 | mpr1-1/mpr1-1 (dcl1-?[3’neo3,HAc]/dcl1-?[3’neo3,HAc], VII) | TSC, Tetrahymena Stock Center | TSC | PMID:15598983 | TSC | 2026-10-10 05:05:53 | 0 | ||||
|
H3.2-Flag-8 Resource Report Resource Website |
RRID:TSC_SD02313 | Tetrahymena thermophila | Don’t know if complete replacement. From the Gorovsky lab, University of Rochester. This strain has been cataloged by the Stock Center but not thawed. | HHT2 (TTHERM_00189180) | Macronucleus: c-terminal HHT2 FLAG tagged | SD02313 | mpr1-1/mpr1-1 (hht2[3’ neo2,FLAGc]; pm-r, VII) | TSC, Tetrahymena Stock Center | TSC | PMID:16908532 PMID:9343391 |
TSC | 2026-10-10 05:05:52 | 0 | ||||
|
∆H3 all, gl KO #28 Resource Report Resource Website |
RRID:TSC_SD01865 | Tetrahymena thermophila | homozygous, Neo cassette knockout before we knew there was HHT4 From the Gorovsky lab, University of Rochester. This strain has been cataloged by the Stock Center but not thawed. | HHT (TTHERM_00570560, TTHERM_00189180, TTHERM_00016170) | Micronucleus: Neo3 KO of major H3s and HHT3 | SD01865 | hht1[∆::neo2]/hht1[∆::neo2]; hhf2,hht2[∆::neo2]/hhf2,hht2[∆::neo2]; hht3[∆::neo2]/hht3[∆::neo2] (mpr1-1; pm-s, mp-r, ?) | TSC, Tetrahymena Stock Center | TSC | PMID:16908532 PMID:15701804 |
TSC | 2026-10-10 05:05:53 | 0 | ||||
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B2086-XS46(6) Resource Report Resource Website |
RRID:TSC_SD01903 | Tetrahymena thermophila | Complete somatic transformant with hta1s134-neo2 replacing the HTA1(HTAX) gene in mac of B2086. From the Gorovsky lab, University of Rochester. This strain has been cataloged by the Stock Center but not thawed. | HTA1 (TTHERM_00790790) | Macronucleus: HTAX has mutation S134A with neo2 cassette in 3’ flank | SD01903 | (htax[S134A,3’neo2]; pm-r, II) | TSC, Tetrahymena Stock Center | TSC | PMID:17242195 | TSC | 2026-10-10 05:05:52 | 0 | ||||
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CU5069 Resource Report Resource Website |
RRID:TSC_SD01194 | Tetrahymena thermophila | SD01194 | chx1-1/chx1-1; pmr1-1/pmr1-1; Nulli 5 (CHX1; pmr1-1; cy-s, pm-r, II) | TSC, Tetrahymena Stock Center | TSC | TSC | 2026-10-10 05:05:52 | 0 |
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