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Integrated Animals is a virtual database currently indexing available animal strains and mutants from: AGSC (Ambystoma), BCBC (mice), BDSC (flies), European Xenopus Resource Center (frog), The National Xenopus Resource (frog), Xenopus Express (frog), CWRU Cystic Fibrosis Mouse Models (mice), DGGR (flies), FlyBase (flies), IMSR (mice), MGI (mice), MMRRC (mice), NSRRC (pig), RGD (rats), Sperm Stem Cell Libraries for Biological Research (rats), Tetrahymena Stock Center (Tetrahymena), WormBase (worms), XGSC (Xiphophorus), ZFIN (zebrafish), and ZIRC (zebrafish). Note, the IMSR data is linked, but users may need to re-execute the search if the top mouse is not returned properly.
Note: BCBC is no longer in service, so the links may not be functional.
http://www.wormbase.org/db/get?name=WBStrain00030488
Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: available
Source References: EMPTY
Synonyms: unc-119(tm4063) III; wgIs765.
Alternate IDs: WB-STRAIN:OP765, CGC_OP765
Notes: Made_by: DKV/MC/PW|"wgIs765 [aptf-3::TY1::EGFP::3xFLAG + unc-119(+)]. TY1::EGFP::3xFLAG tag inserted in frame at C-terminus of coding sequence by recombineering. Expression of transgene confirmed by GFP. References: Sarov M, et al. Nat Methods (2006) 10:839-44. Zhong, M, et al. PLoS Genet (2010) 6(2):e1000848. Strain was constructed as part of the Regulatory Element Project, part of modENCODE (URL: www.modencode.org)."
Proper citation: RRID:WB-STRAIN:WBStrain00030488 Copy
http://www.wormbase.org/db/get?name=WBStrain00030409
Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: available
Source References: EMPTY
Synonyms: unc-119(tm4063) III; wgIs666.
Alternate IDs: WB-STRAIN:OP666, CGC_OP666
Notes: Made_by: DKV/RJT/PW|"wgIs666 [ccch-1::TY1::EGFP::3xFLAG + unc-119(+)]. TY1::EGFP::3xFLAG tag inserted in frame at C-terminus of coding sequence by recombineering. Expression of transgene confirmed by GFP. References: Sarov M, et al. Nat Methods (2006) 10:839-44. Zhong, M, et al. PLoS Genet (2010) 6(2):e1000848. Strain was constructed as part of the Regulatory Element Project, part of modENCODE (URL: www.modencode.org)."
Proper citation: RRID:WB-STRAIN:WBStrain00030409 Copy
http://www.wormbase.org/db/get?name=WBStrain00030408
Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: available
Source References: EMPTY
Synonyms: unc-119(tm4063) III; wgIs665.
Alternate IDs: WB-STRAIN:OP665, CGC_OP665
Notes: Made_by: DKV/RJT/PW|"wgIs665 [spe-10::TY1::EGFP::3xFLAG + unc-119(+)]. TY1::EGFP::3xFLAG tag inserted in frame at C-terminus of coding sequence by recombineering. Expression of transgene confirmed by GFP. References: Sarov M, et al. Nat Methods (2006) 10:839-44. Zhong, M, et al. PLoS Genet (2010) 6(2):e1000848. Strain was constructed as part of the Regulatory Element Project, part of modENCODE (URL: www.modencode.org)."
Proper citation: RRID:WB-STRAIN:WBStrain00030408 Copy
http://www.wormbase.org/db/get?name=WBStrain00030453
Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: available
Source References: EMPTY
Synonyms: unc-119(tm4063) III; wgIs720.
Alternate IDs: WB-STRAIN:OP720, CGC_OP720
Notes: Made_by: DKV/RJT/PW|"Modern strain"|"wgIs720 [lsl-1::TY1::EGFP::3xFLAG + unc-119(+)]. TY1::EGFP::3xFLAG tag inserted in frame at C-terminus of coding sequence by recombineering. Expression of transgene confirmed by GFP. References: Sarov M, et al. Nat Methods (2006) 10:839-44. Zhong, M, et al. PLoS Genet (2010) 6(2):e1000848. Strain was constructed as part of the Regulatory Element Project, part of modENCODE (URL: www.modencode.org)."
Proper citation: RRID:WB-STRAIN:WBStrain00030453 Copy
http://www.wormbase.org/db/get?name=WBStrain00030450
Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: unknown
Source References: EMPTY
Synonyms: unc-119(tm4063) III; wgIs716.
Alternate IDs: WB-STRAIN:OP716
Notes: Made_by: DKV/RJT/PW|"Modern strain"|"wgIs716 [F26F4.8::TY1::EGFP::3xFLAG + unc-119(+)]. TY1::EGFP::3xFLAG tag inserted in frame at C-terminus of coding sequence by recombineering. Expression of transgene confirmed by GFP. References: Sarov M, et al. Nat Methods (2006) 10:839-44. Zhong, M, et al. PLoS Genet (2010) 6(2):e1000848. Strain was constructed as part of the Regulatory Element Project, part of modENCODE (URL: www.modencode.org)."
Proper citation: RRID:WB-STRAIN:WBStrain00030450 Copy
http://www.wormbase.org/db/get?name=WBStrain00030451
Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: available
Source References: EMPTY
Synonyms: unc-119(tm4063) III; wgIs717.
Alternate IDs: WB-STRAIN:OP717, CGC_OP717
Notes: Made_by: DKV/RJT/PW|"wgIs717 [K04C1.3::TY1::EGFP::3xFLAG + unc-119(+)]. TY1::EGFP::3xFLAG tag inserted in frame at C-terminus of coding sequence by recombineering. Expression of transgene confirmed by GFP. References: Sarov M, et al. Nat Methods (2006) 10:839-44. Zhong, M, et al. PLoS Genet (2010) 6(2):e1000848. Strain was constructed as part of the Regulatory Element Project, part of modENCODE (URL: www.modencode.org)."
Proper citation: RRID:WB-STRAIN:WBStrain00030451 Copy
http://www.wormbase.org/db/get?name=WBStrain00030458
Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: available
Source References: EMPTY
Synonyms: unc-119(tm4063) III; wgIs730.
Alternate IDs: WB-STRAIN:OP730, CGC_OP730
Notes: Generated from Paper data WBPaper00060123|"Made_by: DKV/RJT/PW"|"Modern strain"|"wgIs730 [vab-15::TY1::EGFP::3xFLAG + unc-119(+)]. TY1::EGFP::3xFLAG tag inserted in frame at C-terminus of coding sequence by recombineering. Expression of transgene confirmed by GFP. References: Sarov M, et al. Nat Methods (2006) 10:839-44. Zhong, M, et al. PLoS Genet (2010) 6(2):e1000848. Strain was constructed as part of the Regulatory Element Project, part of modENCODE (URL: www.modencode.org)."
Proper citation: RRID:WB-STRAIN:WBStrain00030458 Copy
http://www.wormbase.org/db/get?name=WBStrain00030459
Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: available
Source References: EMPTY
Synonyms: unc-119(tm4063) III; wgIs731.
Alternate IDs: WB-STRAIN:OP731, CGC_OP731
Notes: Made_by: DKV/RJT/PW|"wgIs731 [cdc-14::TY1::EGFP::3xFLAG + unc-119(+)]. TY1::EGFP::3xFLAG tag inserted in frame at C-terminus of coding sequence by recombineering. Expression of transgene confirmed by GFP. References: Sarov M, et al. Nat Methods (2006) 10:839-44. Zhong, M, et al. PLoS Genet (2010) 6(2):e1000848. Strain was constructed as part of the Regulatory Element Project, part of modENCODE (URL: www.modencode.org)."
Proper citation: RRID:WB-STRAIN:WBStrain00030459 Copy
http://www.wormbase.org/db/get?name=WBStrain00030457
Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: available
Source References: EMPTY
Synonyms: unc-119(tm4063) III; wgIs729.
Alternate IDs: WB-STRAIN:OP729, CGC_OP729
Notes: Made_by: Waterston Lab|"wgIs729 [frpr-9::TY1::EGFP::3xFLAG + unc-119(+)]. TY1::EGFP::3xFLAG tag inserted in frame at C-terminus of coding sequence by recombineering. Expression of transgene confirmed by GFP. References: Sarov M, et al. Nat Methods (2006) 10:839-44. Zhong, M, et al. PLoS Genet (2010) 6(2):e1000848. Strain was constructed as part of the Regulatory Element Project, part of modENCODE (URL: www.modencode.org)."
Proper citation: RRID:WB-STRAIN:WBStrain00030457 Copy
http://www.wormbase.org/db/get?name=WBStrain00030463
Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: available
Source References: EMPTY
Synonyms: unc-119(tm4063) III; wgIs738.
Alternate IDs: WB-STRAIN:OP738, CGC_OP738
Notes: Made_by: Waterston Lab|"wgIs738 [Y37F4.6::TY1::EGFP::3xFLAG + unc-119(+)]. TY1::EGFP::3xFLAG tag inserted in frame at C-terminus of coding sequence by recombineering. Expression of transgene confirmed by GFP. References: Sarov M, et al. Nat Methods (2006) 10:839-44. Zhong, M, et al. PLoS Genet (2010) 6(2):e1000848. Strain was constructed as part of the Regulatory Element Project, part of modENCODE (URL: www.modencode.org)."
Proper citation: RRID:WB-STRAIN:WBStrain00030463 Copy
http://www.wormbase.org/db/get?name=WBStrain00030464
Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: available
Source References: EMPTY
Synonyms: unc-119(tm4063) III; wgIs739.
Alternate IDs: WB-STRAIN:OP739, CGC_OP739
Notes: Generated from Paper data WBPaper00060123|"Made_by: DKV/RJT/PW"|"Modern strain"|"wgIs739 [ceh-19::TY1::EGFP::3xFLAG + unc-119(+)]. TY1::EGFP::3xFLAG tag inserted in frame at C-terminus of coding sequence by recombineering. Expression of transgene confirmed by GFP. References: Sarov M, et al. Nat Methods (2006) 10:839-44. Zhong, M, et al. PLoS Genet (2010) 6(2):e1000848. Strain was constructed as part of the Regulatory Element Project, part of modENCODE (URL: www.modencode.org)."
Proper citation: RRID:WB-STRAIN:WBStrain00030464 Copy
http://www.wormbase.org/db/get?name=WBStrain00030501
Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: available
Source References: EMPTY
Synonyms: unc-119(tm4063) III; wgIs789.
Alternate IDs: WB-STRAIN:OP789, CGC_OP789
Notes: Made_by: DKV/MC|"wgIs789 [tab-1::TY1::EGFP::3xFLAG + unc-119(+)]. TY1::EGFP::3xFLAG tag inserted in frame at C-terminus of coding sequence by recombineering. Expression of transgene confirmed by GFP. References: Sarov M, et al. Nat Methods (2006) 10:839-44. Zhong, M, et al. PLoS Genet (2010) 6(2):e1000848. Strain was constructed as part of the Regulatory Element Project, part of modENCODE (URL: www.modencode.org)."
Proper citation: RRID:WB-STRAIN:WBStrain00030501 Copy
http://www.wormbase.org/db/get?name=WBStrain00030465
Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: available
Source References: EMPTY
Synonyms: unc-119(tm4063) III; wgIs740.
Alternate IDs: WB-STRAIN:OP740, CGC_OP740
Notes: Made_by: Waterston Lab|"Modern strain"|"wgIs740 [lin-32::TY1::EGFP::3xFLAG + unc-119(+)]. TY1::EGFP::3xFLAG tag inserted in frame at C-terminus of coding sequence by recombineering. Expression of transgene confirmed by GFP. References: Sarov M, et al. Nat Methods (2006) 10:839-44. Zhong, M, et al. PLoS Genet (2010) 6(2):e1000848. Strain was constructed as part of the Regulatory Element Project, part of modENCODE (URL: www.modencode.org)."
Proper citation: RRID:WB-STRAIN:WBStrain00030465 Copy
http://www.wormbase.org/db/get?name=WBStrain00030551
Source Database: WormBase (WB)
Affected Genes: WBGene00006606(tra-3)
Genomic Alteration: WBGene00006606(tra-3)
Availability: available
Source References: PMID:8244003
Synonyms: tra-3(e1107) IV; ccIs56 V.
Alternate IDs: WB-STRAIN:PD56, CGC_PD56
Notes: ccIs56 [sup-7(st5) +unc-54::lacZ] V. Non-nuclear unc-54::lacZ fusion expressed in nuclei and cytoplasm of body wall muscles.
Proper citation: RRID:WB-STRAIN:WBStrain00030551 Copy
http://www.wormbase.org/db/get?name=WBStrain00030552
Source Database: WormBase (WB)
Affected Genes: WBGene00006789(unc-54)
Genomic Alteration: WBGene00006789(unc-54)
Availability: available
Source References: PMID:8244003
Synonyms: unc-54(e190) I; ccIs126.
Alternate IDs: WB-STRAIN:PD126, CGC_PD126
Notes: ccIs126 [myo-2p::lacZ + unc-54(+)]. lacZ expression in pharyngeal and body wall muscles. Superficially wild-type, but gives some paralyzed animals.
Proper citation: RRID:WB-STRAIN:WBStrain00030552 Copy
http://www.wormbase.org/db/get?name=WBStrain00030557
Source Database: WormBase (WB)
Availability: available
Source References: PMID:37878696
Synonyms: ccTi1594 umnIs7 III.
Alternate IDs: WB-STRAIN:PD2218, CGC_PD2218
Notes: ccTi1594 [mex-5p::GFP::gpr-1::smu-1 3'UTR + Cbr-unc-119(+), III: 680195] III. umnIs7 [myo-2p::GFP + NeoR, III:9421936] III. GFP expression in germline and GFP expression in pharynx. High penetrance of non-Mendelian inheritance. Neomycin resistant. The GPR-1 overexpression transgene consistently confers a high penetrance of non-Mendelian inheritance; fluorescent markers allow tracking of Mendelian and non-Mendelian events. The genomic location of ccTi1594 is with respect to the WEBcel235 assembly.|"Supplementary_genotype ccTi1594 [mex-5p::GFP::gpr-1::smu-1 3'UTR + Cbr-unc-119(+), III: 680195] III. umnIs7 [myo-2p::GFP + NeoR, III:9421936] III"
Proper citation: RRID:WB-STRAIN:WBStrain00030557 Copy
http://www.wormbase.org/db/get?name=WBStrain00030558
Source Database: WormBase (WB)
Availability: available
Source References: PMID:39300074
Synonyms: ccTi1594 umnIs27 III.
Alternate IDs: WB-STRAIN:PD2220, CGC_PD2220
Notes: ccTi1594 [mex-5p::GFP::gpr-1::smu-1 3'UTR + Cbr-unc-119(+), III: 680195] III. umnIs27 [myo-2::GFP + NeoR, III: 8856215 (intergenic)] III. GFP expression in germline and GFP expression in pharynx. High penetrance of non-Mendelian inheritance. Neomycin resistant. The GPR-1 overexpression transgene consistently confers a high penetrance of non-Mendelian inheritance; fluorescent markers allow tracking of Mendelian and non-Mendelian events. The genomic location of ccTi1594 is with respect to the WEBcel235 assembly.
Proper citation: RRID:WB-STRAIN:WBStrain00030558 Copy
http://www.wormbase.org/db/get?name=WBStrain00030555
Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: available
Source References: EMPTY
Synonyms: ccTi1594 unc-119(ed3) III.
Alternate IDs: WB-STRAIN:PD1594, CGC_PD1594
Notes: ccTi1594 [mex-5p::GFP::gpr-1::smu-1 3'UTR + Cbr-unc-119(+), III: 680195] III. GFP expression in germline. Transgene rescues unc-119(ed3). Improved GPR-1 over-expression transgene appears to be stably expressed in the germline at a wide range of temperatures and does not require special handling. (unlike other GPR-1 overexpressing transgenes previously described in the literature). The GPR-1 overexpression transgene consistently confers a high penetrance of non-Mendelian inheritance. Neomycin resistant. The genomic location of ccTi1594 is with respect to the WEBcel235 assembly.|"Made_by: Christian Froekjaer Jensen"
Proper citation: RRID:WB-STRAIN:WBStrain00030555 Copy
http://www.wormbase.org/db/get?name=WBStrain00030556
Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: available
Source References: PMID:38946472
Synonyms: ccTi1594 unc-119(ed3) III; hjSi20 IV.
Alternate IDs: WB-STRAIN:PD2217, CGC_PD2217
Notes: ccTi1594 [mex-5p::GFP::gpr-1::smu-1 3'UTR + Cbr-unc-119(+), III: 680195] III. hjSi20 [myo-2p::mCherry::unc-54 3'UTR] IV. GFP expression in germline. mCherry expression in pharynx. The ccTi1594 transgene rescues unc-119(ed3). High penetrance of non-Mendelian inheritance. The GPR-1 overexpression transgene consistently confers a high penetrance of non-Mendelian inheritance; fluorescent markers allow tracking of Mendelian and non-Mendelian events. The genomic location of ccTi1594 is with respect to the WEBcel235 assembly.
Proper citation: RRID:WB-STRAIN:WBStrain00030556 Copy
http://www.wormbase.org/db/get?name=WBStrain00030553
Source Database: WormBase (WB)
Availability: unknown
Source References: PMID:33313486, PMID:33458604, PMID:33693840, PMID:34156835, PMID:37008729, PMID:36595469, PMID:37170380, PMID:37590248, PMID:37777524, PMID:38596360, PMID:38488606, PMID:38771761, PMID:39712935
Synonyms: EMPTY
Alternate IDs: WB-STRAIN:PD1074
Notes: A defined and recently cloned population of animals derived from the original Bristol variant of C. elegans originally obtained by Brenner from E. Dougherty with no known history of mutagenesis. Brenners original population, called N2, was used as the basis for the vast majority of laboratory strains in use currently. No early frozen stock of the unmutagenized N2 population currently exists, but later stocks were available from several laboratories. PD1074 is a clonal population founded by picking a single worm of one such stock, VC3510. VC3510 in turn derives from a subpopulation of N2 described in the literature as VC2010. PD1074 is intended to be used as a wild type reference strain with the closely matched genome assembly of Yoshimura et al (ref) available on Wormbase as VC2010-1.0. (ENA study accession PRJEB28388; assembly accession GCA_900538205). We note that PD1074 is expected to be largely similar to most lab N2 strains, but that as a clonal isolate derived from N2, there will be some loci that will vary compared to any other particular N2 isolate. One such example is a partial deletion of the alh-2 locus in PD1074. Additional loci that were found to vary between the prior N2 reference genome (WormBase release WS264) and the VC2010-1.0 assembly are detailed in supplemental table 8 in Yoshimura et al (ref).|"A defined and recently cloned population of animals derived from the original Bristol variant of C. elegans originally obtained by Brenner from E. Dougherty with no known history of mutagenesis. Brenners original population, called N2, was used as the basis for the vast majority of laboratory strains in use currently. No early frozen stock of the unmutagenized N2 population currently exists, but later stocks were available from several laboratories. PD1074 is a clonal population founded by picking a single worm of one such stock, VC3510. VC3510 in turn derives from a subpopulation of N2 described in the literature as VC2010. PD1074 is intended to be used as a wild type reference strain with the closely matched genome assembly of Yoshimura, et al. (Genome Res. 2019 Jun;29(6):1009-1022) available on Wormbase as VC2010-1.0. (ENA study accession PRJEB28388; assembly accession GCA_900538205). We note that PD1074 is expected to be largely similar to most lab N2 strains, but that as a clonal isolate derived from N2, there will be some loci that will vary compared to any other particular N2 isolate. One such example is a partial deletion of the alh-2 locus in PD1074. Additional loci that were found to vary between the prior N2 reference genome (WormBase release WS264) and the VC2010-1.0 assembly are detailed in supplemental table 8 in Yoshimura, et al, (2019)."|"Added Wild_Isolate tag as genotype info suggesting that they were sampled from the wild."|"Made_by: Karen Artiles & Mark Edgley"|"no longer available from the CGC."|"Supplementary_genotype"|"WBStrain provided so WBPaper00061243 paper added based on AFP_Strain data."|"WBStrain provided so WBPaper00061573 paper added based on AFP_Strain data."
Proper citation: RRID:WB-STRAIN:WBStrain00030553 Copy
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