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Integrated Animals is a virtual database currently indexing available animal strains and mutants from: AGSC (Ambystoma), BCBC (mice), BDSC (flies), European Xenopus Resource Center (frog), The National Xenopus Resource (frog), Xenopus Express (frog), CWRU Cystic Fibrosis Mouse Models (mice), DGGR (flies), FlyBase (flies), IMSR (mice), MGI (mice), MMRRC (mice), NSRRC (pig), RGD (rats), Sperm Stem Cell Libraries for Biological Research (rats), Tetrahymena Stock Center (Tetrahymena), WormBase (worms), XGSC (Xiphophorus), ZFIN (zebrafish), and ZIRC (zebrafish). Note, the IMSR data is linked, but users may need to re-execute the search if the top mouse is not returned properly.
Note: BCBC is no longer in service, so the links may not be functional.
https://www.jax.org/strain/034545
Source Database: JAX Mice and Services
Affected Genes: apolipoprotein E|TAR DNA binding protein|microtubule-associated protein tau
Genomic Alteration: targeted mutation 1.1; MODEL-AD Center|endonuclease-mediated mutation 9; Cathy Lutz|endonuclease-mediated mutation 2; Cathy Lutz
Availability: embryo
Notes: gene symbol note: apolipoprotein E|TAR DNA binding protein|microtubule-associated protein tau; mutant strain: APOE|Tardbp|Apoe|Mapt
Proper citation: RRID:IMSR_JAX:034545 Copy
https://www.jax.org/strain/034543
Source Database: JAX Mice and Services
Affected Genes: TAR DNA binding protein|amyloid beta precursor protein|apolipoprotein E
Genomic Alteration: endonuclease-mediated mutation 9; Cathy Lutz|endonuclease-mediated mutation 5; Michael Sasner|targeted mutation 1.1; MODEL-AD Center
Availability: embryo
Notes: gene symbol note: TAR DNA binding protein|amyloid beta precursor protein|apolipoprotein E; mutant strain|congenic strain: Tardbp|App|Apoe|APOE
Proper citation: RRID:IMSR_JAX:034543 Copy
https://www.jax.org/strain/034655
Source Database: JAX Mice and Services
Affected Genes: transgene insertion M; Raghu Kalluri
Genomic Alteration: transgene insertion M; Raghu Kalluri
Availability: embryo
Synonyms: C57BL/6-Tg(Fap-TK)MRkl/J
Notes: gene symbol note: transgene insertion M; Raghu Kalluri; mutant strain|congenic strain: Tg(Fap-TK)MRkl
Proper citation: RRID:IMSR_JAX:034655 Copy
https://www.jax.org/strain/034810
Source Database: JAX Mice and Services
Affected Genes: secreted phosphoprotein 1
Genomic Alteration: targeted mutation 1; Brigid L Hogan
Availability: embryo
Notes: gene symbol note: secreted phosphoprotein 1; mutant strain: Spp1
Proper citation: RRID:IMSR_JAX:034810 Copy
https://www.jax.org/strain/035491
Source Database: JAX Mice and Services
Affected Genes: matrix metallopeptidase 28 (epilysin)
Genomic Alteration: targeted mutation 1; Anne M Manicone
Availability: embryo
Notes: gene symbol note: matrix metallopeptidase 28 (epilysin); mutant strain|congenic strain: Mmp28
Proper citation: RRID:IMSR_JAX:035491 Copy
https://www.jax.org/strain/035474
Source Database: JAX Mice and Services
Affected Genes: transgene insertion 10; Maki Yamada
Genomic Alteration: transgene insertion 10; Maki Yamada
Availability: embryo
Notes: gene symbol note: transgene insertion 10; Maki Yamada; mutant strain|congenic strain: Tg(Arc-tTA;-EGFP/Capzb*)10Mkyph
Proper citation: RRID:IMSR_JAX:035474 Copy
https://www.jax.org/strain/035347
Source Database: JAX Mice and Services
Availability: embryo
Notes: gene symbol note: ; wild-derived inbred strain:
Proper citation: RRID:IMSR_JAX:035347 Copy
https://www.jax.org/strain/035843
Source Database: JAX Mice and Services
Affected Genes: FMS-like tyrosine kinase 3|interleukin 2 receptor; gamma chain|interleukin 3|transgene insertion 1; CJ Eaves|protein kinase; DNA activated; catalytic polypeptide|colony stimulating factor 2|cytomegalovirus|KIT ligand
Genomic Alteration: endonuclease-mediated mutation 1; Karolina Palucka|targeted mutation 1; Warren J Leonard|transgene insertion 1; CJ Eaves|severe combined immunodeficiency
Availability: embryo
Notes: gene symbol note: FMS-like tyrosine kinase 3|interleukin 2 receptor; gamma chain|interleukin 3|transgene insertion 1; CJ Eaves|protein kinase; DNA activated; catalytic polypeptide|colony stimulating factor 2|cytomegalovirus|KIT ligand; mutant strain: Flt3|Il2rg|IL3|Tg(CMV-IL3;CSF2;KITLG)1Eav|Prkdc|CSF2|CMV|KITLG
Proper citation: RRID:IMSR_JAX:035843 Copy
https://www.jax.org/strain/035929
Source Database: JAX Mice and Services
Affected Genes: nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor; alpha
Genomic Alteration: targeted mutation 1.1; Shigeki Miyamoto
Availability: embryo
Notes: gene symbol note: nuclear factor of kappa light polypeptide gene enhancer in B cells inhibitor; alpha; mutant strain|congenic strain: Nfkbia
Proper citation: RRID:IMSR_JAX:035929 Copy
https://www.jax.org/strain/035907
Source Database: JAX Mice and Services
Affected Genes: transgene insertion M; Raghu Kalluri
Genomic Alteration: transgene insertion M; Raghu Kalluri
Availability: embryo
Notes: gene symbol note: transgene insertion M; Raghu Kalluri; mutant strain|congenic strain: Tg(Fap-TK)MRkl
Proper citation: RRID:IMSR_JAX:035907 Copy
https://www.jax.org/strain/036400
Source Database: JAX Mice and Services
Affected Genes: ubiquitin specific peptidase 14
Genomic Alteration: neuroscience mutagenesis facility; 375
Availability: embryo
Notes: gene symbol note: ubiquitin specific peptidase 14; mutant strain: Usp14
Proper citation: RRID:IMSR_JAX:036400 Copy
https://www.jax.org/strain/036336
Source Database: JAX Mice and Services
Affected Genes: thyrotropin releasing hormone receptor|growth hormone releasing hormone receptor
Genomic Alteration: targeted mutation 1.1; David E Harrison
Availability: embryo
Notes: gene symbol note: thyrotropin releasing hormone receptor|growth hormone releasing hormone receptor; mutant strain|congenic strain: Trhr|Ghrhr
Proper citation: RRID:IMSR_JAX:036336 Copy
https://www.jax.org/strain/036727
Source Database: JAX Mice and Services
Affected Genes: gene trap ROSA 26; Philippe Soriano
Genomic Alteration: targeted mutation 1.1; Saverio Bellusci
Availability: embryo
Synonyms: C57BL/6-Gt(ROSA)26Sor
Notes: gene symbol note: gene trap ROSA 26; Philippe Soriano; mutant strain: Gt(ROSA)26Sor
Proper citation: RRID:IMSR_JAX:036727 Copy
https://www.jax.org/strain/036930
Source Database: JAX Mice and Services
Affected Genes: collagen; type III; alpha 1
Genomic Alteration: endonuclease-mediated mutation 2; Harry C Dietz
Availability: embryo
Synonyms: C57BL/6J-Col3a1
Notes: gene symbol note: collagen; type III; alpha 1; mutant stock: Col3a1
Proper citation: RRID:IMSR_JAX:036930 Copy
https://archive.har.mrc.ac.uk/stock?id=10282
Source Database: MRC Harwell
Affected Genes: apolipoprotein C-III
Genomic Alteration: endonuclease-mediated mutation 2; Harwell
Availability: embryo
Notes: gene symbol note: apolipoprotein C-III; coisogenic strain: Apoc3
Proper citation: RRID:IMSR_HAR:10282 Copy
https://archive.har.mrc.ac.uk/stock?id=10163
Source Database: MRC Harwell
Affected Genes: deiodinase; iodothyronine; type II
Genomic Alteration: endonuclease-mediated mutation 1; Harwell
Availability: embryo
Notes: gene symbol note: deiodinase; iodothyronine; type II; coisogenic strain: Dio2
Proper citation: RRID:IMSR_HAR:10163 Copy
https://archive.har.mrc.ac.uk/stock?id=10284
Source Database: MRC Harwell
Affected Genes: solute carrier family 30 (zinc transporter); member 3
Genomic Alteration: endonuclease-mediated mutation 1; Harwell
Availability: embryo
Notes: gene symbol note: solute carrier family 30 (zinc transporter); member 3; coisogenic strain: Slc30a3
Proper citation: RRID:IMSR_HAR:10284 Copy
https://archive.har.mrc.ac.uk/stock?id=10162
Source Database: MRC Harwell
Affected Genes: NK1 homeobox 2
Genomic Alteration: endonuclease-mediated mutation 1; Harwell
Availability: embryo
Notes: gene symbol note: NK1 homeobox 2; mutant strain: Nkx1-2
Proper citation: RRID:IMSR_HAR:10162 Copy
https://archive.har.mrc.ac.uk/stock?id=10286
Source Database: MRC Harwell
Affected Genes: protein phosphatase 2; regulatory subunit B''; gamma
Genomic Alteration: endonuclease-mediated mutation 1; Harwell
Availability: embryo
Notes: gene symbol note: protein phosphatase 2; regulatory subunit B''; gamma; coisogenic strain: Ppp2r3c
Proper citation: RRID:IMSR_HAR:10286 Copy
https://archive.har.mrc.ac.uk/stock?id=10051
Source Database: MRC Harwell
Affected Genes: CD74 antigen (invariant polypeptide of major histocompatibility complex; class II antigen-associated)
Genomic Alteration: endonuclease-mediated mutation 1; Harwell
Availability: embryo
Notes: gene symbol note: CD74 antigen (invariant polypeptide of major histocompatibility complex; class II antigen-associated); coisogenic strain: Cd74
Proper citation: RRID:IMSR_HAR:10051 Copy
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