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Integrated Animals is a virtual database currently indexing available animal strains and mutants from: AGSC (Ambystoma), BCBC (mice), BDSC (flies), European Xenopus Resource Center (frog), The National Xenopus Resource (frog), Xenopus Express (frog), CWRU Cystic Fibrosis Mouse Models (mice), DGGR (flies), FlyBase (flies), IMSR (mice), MGI (mice), MMRRC (mice), NSRRC (pig), RGD (rats), Sperm Stem Cell Libraries for Biological Research (rats), Tetrahymena Stock Center (Tetrahymena), WormBase (worms), XGSC (Xiphophorus), ZFIN (zebrafish), and ZIRC (zebrafish). Note, the IMSR data is linked, but users may need to re-execute the search if the top mouse is not returned properly.
Note: BCBC is no longer in service, so the links may not be functional.
http://www.wormbase.org/db/get?name=WBStrain00008570
Source Database: WormBase (WB)
Affected Genes: WBGene00000266(bre-1)
Genomic Alteration: WBGene00000266(bre-1)
Availability: available
Source References: PMID:38719808
Synonyms: bre-1(ye4) IV.
Alternate IDs: WB-STRAIN:HY496, CGC_HY496
Notes: Made_by: Elyassnia/Aroian|"Resistant to Cry5B Bt toxin. Reduced brood size."
Proper citation: RRID:WB-STRAIN:WBStrain00008570 Copy
http://www.wormbase.org/db/get?name=WBStrain00008574
Source Database: WormBase (WB)
Affected Genes: WBGene00003132(mat-1)
Genomic Alteration: WBGene00003132(mat-1)
Availability: available
Source References: PMID:33355089
Synonyms: mat-1(ye121) I.
Alternate IDs: WB-STRAIN:HY604, CGC_HY604
Notes: Made_by: C. Rappleye|"Temperature-sensitive embryonic lethal, maintain at 15C. Shift L4 hermaphrodites to 25C overnight for mutant embryos. Mutant embryos are sensitive to osmolarity and pressure. Previously called pod-5(ye121)."
Proper citation: RRID:WB-STRAIN:WBStrain00008574 Copy
http://www.wormbase.org/db/get?name=WBStrain00008575
Source Database: WormBase (WB)
Affected Genes: WBGene00003133(apc-1)
Genomic Alteration: WBGene00003133(apc-1)
Availability: available
Synonyms: apc-1(or319) II.
Alternate IDs: WB-STRAIN:HY607, CGC_HY607
Notes: Made_by: C. Rappleye|"Temperature-sensitive embryonic lethal, maintain at 15C. Shift L4 hermaphrodites to 24C overnight for mutant embryos. Mutant embryos are sensitive to osmolarity and pressure. Previously called pod-3 and mat-2."
Proper citation: RRID:WB-STRAIN:WBStrain00008575 Copy
http://www.wormbase.org/db/get?name=WBStrain00008576
Source Database: WormBase (WB)
Affected Genes: WBGene00001864(him-5)|WBGene00003133(apc-1)
Genomic Alteration: WBGene00001864(him-5), WBGene00003133(apc-1)
Availability: available
Synonyms: apc-1(or374) II; him-5(e1490) V.
Alternate IDs: WB-STRAIN:HY618, CGC_HY618
Notes: Made_by: C. Rappleye|"Temperature-sensitive embryonic lethal, maintain at 15C. Shift L4 hermaphrodites to 25C overnight for mutant embryos. Mutant embryos are sensitive to osmolarity and pressure. Previously called pod-3 and mat-2.."
Proper citation: RRID:WB-STRAIN:WBStrain00008576 Copy
http://www.wormbase.org/db/get?name=WBStrain00008556
Source Database: WormBase (WB)
Affected Genes: WBGene00000898(daf-2)|WBGene00000912(daf-16)
Genomic Alteration: WBGene00000898(daf-2), WBGene00000912(daf-16)
Availability: available
Source References: PMID:37577954
Synonyms: daf-16(mgDf50) I; daf-2(e1370) III.
Alternate IDs: WB-STRAIN:HT1890, CGC_HT1890
Notes: Short-lived. Dauer-defective (Daf-d). Maintain under standard conditions. Reference: Kwon ES, et al. Nature. 2010 Jul 22;466(7305):498-502.|"WBStrain provided so WBPaper00061869 paper added based on AFP_Strain data."
Proper citation: RRID:WB-STRAIN:WBStrain00008556 Copy
http://www.wormbase.org/db/get?name=WBStrain00008558
Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: available
Synonyms: unc-119(ed3) III; wwEx85.
Alternate IDs: WB-STRAIN:HT2099, CGC_HT2099
Notes: Made_by: Walhout/Tissenbaum|"wwEx85 [daf-28p::GFP + unc-119(+)]. Pick wild-type (non-Unc) to maintain. Reference: Ritter AD, et al. Genome Res. 2013 Mar 28."
Proper citation: RRID:WB-STRAIN:WBStrain00008558 Copy
http://www.wormbase.org/db/get?name=WBStrain00008560
Source Database: WormBase (WB)
Affected Genes: WBGene00003026(lin-41)
Genomic Alteration: WBGene00003026(lin-41)
Availability: available
Synonyms: lin-41(xe11) I.
Alternate IDs: WB-STRAIN:HW1329, CGC_HW1329
Notes: Egg-laying (Egl) defects and subsequent internal hatching of progeny (Bagging) in > 95% of animals. xe11 is a C-to-U point mutation in each of the endogenous let-7 complementary sites, LCS1 and LCS2 [I:C9,335,211T & I:C9,335,260T]. xe11 is a weak gain-of-function allele: mutation of two functionally relevant let-7 binding sites impairs repression by let-7 causing over-expression of LIN-41 in L4 stage animals. Reference: Ecsedi M, et al. Dev Cell. 2015 Feb 9;32(3):335-44. Do not distribute this strain; other labs should request it directly from the CGC. This strain cannot be distributed to commercial organizations. This strain cannot be used for any commercial purpose or for work on human subjects.|"Egg-laying (Egl) defects and subsequent internal hatching of progeny (Bagging) in > 95% of animals. xe11 is a C-to-U point mutation in each of the endogenous let-7 complementary sites, LCS1 and LCS2 [I:C9,335,211T & I:C9,335,260T]. xe11 is a weak gain-of-function allele: mutation of two functionally relevant let-7 binding sites impairs repression by let-7 causing overexpression of LIN-41 in L4 stage animals. Reference: Ecsedi M, et al. Dev Cell. 2015 Feb 9;32(3):335-44. Do not distribute this strain; other labs should request it directly from the CGC. This strain cannot be distributed to commercial organizations. This strain cannot be used for any commercial purpose or for work on human subjects."|"Made_by: Matyas Escedi"
Proper citation: RRID:WB-STRAIN:WBStrain00008560 Copy
http://www.wormbase.org/db/get?name=WBStrain00008561
Source Database: WormBase (WB)
Affected Genes: WBGene00003015(lin-29)
Genomic Alteration: WBGene00003015(lin-29)
Availability: available
Synonyms: lin-29(xe61[lin-29::gfp::3xflag]) II
Alternate IDs: WB-STRAIN:HW1822, CGC_HW1822
Notes: Low penetrance Pvl (i.e., tagged protein appears not fully functional). CRISPR/Cas9-engineered allele adds GFP and 3xflag tag to LIN-29. Do not distribute this strain; other labs should request it directly from the CGC. This strain cannot be distributed to commercial organizations. This strain cannot be used for any commercial purpose or for work on human subjects. Reference: Aeschimann F, et al., Mol Cell. 2017 Feb 2;65(3):476-489.
Proper citation: RRID:WB-STRAIN:WBStrain00008561 Copy
http://www.wormbase.org/db/get?name=WBStrain00008562
Source Database: WormBase (WB)
Affected Genes: WBGene00003015(lin-29)
Genomic Alteration: WBGene00003015(lin-29)
Availability: available
Synonyms: lin-29(xe63[gfp::3xflag::lin-29a]) II.
Alternate IDs: WB-STRAIN:HW1826, CGC_HW1826
Notes: Superficially wild-type. CRISPR/Cas9-engineered allele adds GFP and 3xflag tag to the N-terminus of LIN-29A. Do not distribute this strain; other labs should request it directly from the CGC. This strain cannot be distributed to commercial organizations. This strain cannot be used for any commercial purpose or for work on human subjects. Reference: Aeschimann F, et al., (2019). A single let-7 target to coordinate transition to adulthood. Life Science Alliance 2, e201900335. URL: dx.doi.org/10.26508/lsa.201900335 )
Proper citation: RRID:WB-STRAIN:WBStrain00008562 Copy
http://www.wormbase.org/db/get?name=WBStrain00008563
Source Database: WormBase (WB)
Affected Genes: WBGene00003015(lin-29)
Genomic Alteration: WBGene00003015(lin-29)
Availability: available
Synonyms: lin-29(xe40 xe65[lin-29b::gfp::3xflag]) II.
Alternate IDs: WB-STRAIN:HW1835, CGC_HW1835
Notes: Partially penetrant Pvl and Egl. xe40 specifically disrupts the LIN-29A isoform. The GFP tag was inserted at the shared C-terminus of LIN-29A/B in the xe40 background, so only the labeled B isoform is expressed. Do not distribute this strain; other labs should request it directly from the CGC. This strain cannot be distributed to commercial organizations. This strain cannot be used for any commercial purpose or for work on human subjects. Reference: Pereira et al., (2019) Timing mechanism of sexually dimorphic nervous system differentiation. eLIFE 8: e42078. https:
Proper citation: RRID:WB-STRAIN:WBStrain00008563 Copy
http://www.wormbase.org/db/get?name=WBStrain00008566
Source Database: WormBase (WB)
Affected Genes: WBGene00001078(dpy-19)|WBGene00001609(glp-1)|WBGene00004075(pod-1)|WBGene00006768(unc-32)
Genomic Alteration: WBGene00001078(dpy-19), WBGene00001609(glp-1), WBGene00004075(pod-1), WBGene00006768(unc-32)
Availability: available
Source References: PMID:10557211
Synonyms: unc-32(e189) pod-1(ye11)/qC1 [dpy-19(e1259) glp-1(q339)] III.
Alternate IDs: WB-STRAIN:HY463, CGC_HY463
Notes: Heterozygotes are WT and segregate WT, Sterile Dpys and Uncs. Unc worms produce only dead embyros due to strict maternal effect pod-1(ye11) mutation. Embryos from pod-1 homozygous hermaphrodites are osmotically sensitive and exhibit polarity defects.|"Made_by: Chad Rappleye"
Proper citation: RRID:WB-STRAIN:WBStrain00008566 Copy
http://www.wormbase.org/db/get?name=WBStrain00008617
Source Database: WormBase (WB)
Availability: available
Synonyms: quEx128.
Alternate IDs: WB-STRAIN:IC611, CGC_IC611
Notes: quEx128 [npr-9::GFP + rol-6(su1006)]. Maintain by picking Rollers. ZK455.3 is npr-9 and is expressed in AIB neuron.
Proper citation: RRID:WB-STRAIN:WBStrain00008617 Copy
http://www.wormbase.org/db/get?name=WBStrain00008618
Source Database: WormBase (WB)
Affected Genes: WBGene00013974(npr-9)
Genomic Alteration: WBGene00013974(npr-9)
Availability: available
Synonyms: npr-9(tm1652) X.
Alternate IDs: WB-STRAIN:IC683, CGC_IC683
Notes: EMPTY
Proper citation: RRID:WB-STRAIN:WBStrain00008618 Copy
http://www.wormbase.org/db/get?name=WBStrain00008619
Source Database: WormBase (WB)
Availability: available
Synonyms: quEx162.
Alternate IDs: WB-STRAIN:IC692, CGC_IC692
Notes: quEx162 [sax-3p::GFP + rol-6(su1006)]. Pick GFP to maintain. Very bright GFP in early embryos (after 24 cell stage). Not all GFP+ worms are rolling.
Proper citation: RRID:WB-STRAIN:WBStrain00008619 Copy
http://www.wormbase.org/db/get?name=WBStrain00008621
Source Database: WormBase (WB)
Affected Genes: WBGene00006762(unc-25)|WBGene00006869(vab-2)
Genomic Alteration: WBGene00006762(unc-25), WBGene00006869(vab-2)
Availability: available
Synonyms: juIs73 II; vab-2(ju1) IV.
Alternate IDs: WB-STRAIN:IC700, CGC_IC700
Notes: juIs73 [unc-25p::GFP] II.
Proper citation: RRID:WB-STRAIN:WBStrain00008621 Copy
http://www.wormbase.org/db/get?name=WBStrain00008603
Source Database: WormBase (WB)
Affected Genes: WBGene00001864(him-5)|WBGene00013695(epg-8)
Genomic Alteration: WBGene00001864(him-5), WBGene00013695(epg-8)
Availability: available
Source References: PMID:32302543, PMID:35065714, PMID:37432924
Synonyms: epg-8(bp251) I; him-5(e1490) V.
Alternate IDs: WB-STRAIN:HZ1691, CGC_HZ1691
Notes: Him; ~30% male.|"WBStrain mapped, WBPaper00059578 added based on AFP_Strain data."
Proper citation: RRID:WB-STRAIN:WBStrain00008603 Copy
http://www.wormbase.org/db/get?name=WBStrain00008606
Source Database: WormBase (WB)
Affected Genes: WBGene00000386(cdc-25.1)|WBGene00006808(unc-76)
Genomic Alteration: WBGene00000386(cdc-25.1), WBGene00006808(unc-76)
Availability: available
Synonyms: cdc-25.1(ij48) I; unc-76(e911) ijIs10 V.
Alternate IDs: WB-STRAIN:IA123, CGC_IA123
Notes: ijIs10 [cpr-5::GFP::lacZ + unc-76(+)]. Extra intestinal cells.
Proper citation: RRID:WB-STRAIN:WBStrain00008606 Copy
http://www.wormbase.org/db/get?name=WBStrain00008608
Source Database: WormBase (WB)
Affected Genes: WBGene00000440(ceh-17)
Genomic Alteration: WBGene00000440(ceh-17)
Availability: available
Source References: PMID:32811254, PMID:36652499, PMID:36924492, PMID:39738055, PMID:40114851
Synonyms: ceh-17(np1) I.
Alternate IDs: WB-STRAIN:IB16, CGC_IB16
Notes: Mutagen:UV/TMP|"Supplementary_genotype ceh-17(np1) I"|"WBStrain mapped, WBPaper00060107 added based on AFP_Strain data."|"WT behavioral phenotype. Axon guidance defect in ceh-17 expressing neurons ALA and 4SIA. ceh-17 = D1007.1, a C. elegans paired homeodomain transcription factor, Phox2 orthologue. np1 is a molecular null. np1 is a 1353 bp deletion inculding 549 bp upstream of the initiator ATG and extending to the 5th codon of the homeodomain. [NOTE: Miyazaki, et al. (2022) report that this strain carries the fln-2(ot611) mutation in the background, and outcrossing the strain resulted in significantly reduced quiescence during lethargus.]"
Proper citation: RRID:WB-STRAIN:WBStrain00008608 Copy
http://www.wormbase.org/db/get?name=WBStrain00004938
Source Database: WormBase (WB)
Availability: available
Synonyms: umnTi2 III.
Alternate IDs: WB-STRAIN:CGC5, CGC_CGC5
Notes: Made_by: Britt Werre|"umnTi2 [eft-3p::GFP + unc-119(+)]. Integration site: (III:+13.25 cM/nt 11,816,400). Might still contain unc-119(ed3) in background."
Proper citation: RRID:WB-STRAIN:WBStrain00004938 Copy
http://www.wormbase.org/db/get?name=WBStrain00004939
Source Database: WormBase (WB)
Availability: available
Synonyms: umnTi3 I.
Alternate IDs: WB-STRAIN:CGC6, CGC_CGC6
Notes: Made_by: Britt Werre|"umnTi3 [eft-3p::GFP + unc-119(+)]. Integration site: (I:+30 cM/nt 15,065,881). Might still contain unc-119(ed3) in background."
Proper citation: RRID:WB-STRAIN:WBStrain00004939 Copy
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