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Integrated Animals is a virtual database currently indexing available animal strains and mutants from: AGSC (Ambystoma), BCBC (mice), BDSC (flies), European Xenopus Resource Center (frog), The National Xenopus Resource (frog), Xenopus Express (frog), CWRU Cystic Fibrosis Mouse Models (mice), DGGR (flies), FlyBase (flies), IMSR (mice), MGI (mice), MMRRC (mice), NSRRC (pig), RGD (rats), Sperm Stem Cell Libraries for Biological Research (rats), Tetrahymena Stock Center (Tetrahymena), WormBase (worms), XGSC (Xiphophorus), ZFIN (zebrafish), and ZIRC (zebrafish). Note, the IMSR data is linked, but users may need to re-execute the search if the top mouse is not returned properly.
Note: BCBC is no longer in service, so the links may not be functional.
http://www.cfmice.org/cf-mouse-strains.html
Source Database: Cystic Fibrosis Mouse Model Core
Affected Genes: cystic fibrosis transmembrane conductance regulator
Genomic Alteration: endonuclease-mediated mutation 3; Case Western Reserve University
Availability: live
Notes: gene symbol note: cystic fibrosis transmembrane conductance regulator; coisogenic strain: Cftr
Proper citation: RRID:IMSR_CWR:CGX Copy
https://www.taconic.com/transgenic-mouse-model/apob100
Source Database: Taconic Biosciences
Genomic Alteration: transgene insertion 1102; Stephen G Young
Availability: live
Synonyms: ApoB100 MICROINJECTED - C57BL/6 Background. B6.Cg-Tg(APOB)1102Sgy/Tac
Notes: gene symbol note: ; mutant strain|congenic strain:
Proper citation: RRID:IMSR_TAC:1004 Copy
https://www.taconic.com/rat-model/lrrk2-g2019s
Source Database: Taconic Biosciences
Availability: live
Notes: gene symbol note: ; mutant strain:
Proper citation: RRID:IMSR_TAC:10681 Copy
https://www.taconic.com/transgenic-mouse-model/oatp1a1b-cluster-knockout-mouse
Source Database: Taconic Biosciences
Availability: live
Notes: gene symbol note: ; mutant strain:
Proper citation: RRID:IMSR_TAC:10707 Copy
http://www.cfmice.org/cf-mouse-strains.html
Source Database: Cystic Fibrosis Mouse Model Core
Affected Genes: cystic fibrosis transmembrane conductance regulator
Genomic Alteration: targeted mutation 1; Case Western Reserve University
Availability: live
Notes: gene symbol note: cystic fibrosis transmembrane conductance regulator; congenic strain: Cftr
Proper citation: RRID:IMSR_CWR:CFC Copy
https://www.taconic.com/transgenic-mouse-model/rag2ot-ii-11490
Source Database: Taconic Biosciences
Availability: live
Synonyms: B6.Cg-Rag2
Notes: gene symbol note: ; mutant strain:
Proper citation: RRID:IMSR_TAC:11490 Copy
http://taconic.com/mouse-model/cyp2a13-cyp2f1-cyp2b6
Source Database: Taconic Biosciences
Affected Genes: |cytochrome P450; family 2; subfamily f; polypeptide 2
Genomic Alteration: transgene insertion 349; Xinxin Ding|targeted mutation 1; Xinxin Ding
Availability: live
Notes: gene symbol note: |cytochrome P450; family 2; subfamily f; polypeptide 2; mutant strain|inbred strain: |Cyp2f2
Proper citation: RRID:IMSR_TAC:10835 Copy
https://www.taconic.com/transgenic-mouse-model/humanized-oatp1b11b3-mouse
Source Database: Taconic Biosciences
Availability: live
Notes: gene symbol note: ; mutant strain:
Proper citation: RRID:IMSR_TAC:11594 Copy
https://www.taconic.com/transgenic-mouse-model/rash2
Source Database: Taconic Biosciences
Genomic Alteration: transgene insertion 2; Central Institute for Experimental Animals; Japan
Availability: live
Synonyms: rasH2 MICROINJECTED - BALB/cBy x C57BL/6 F1 Hybrid Background. (BALB/cByJJic x C57BL/6JJic-Tg(HRAS)2Jic)F1/Tac
Notes: gene symbol note: ; unclassified|mutant stock:
Proper citation: RRID:IMSR_TAC:1178 Copy
https://en.gempharmatech.com/product/search_1.html?searchKey=T044551
Source Database: GemPharmatech
Affected Genes: mortality factor 4 like 2
Availability: live
Synonyms: C57BL/6JGpt-Morf4l2
Notes: gene symbol note: mortality factor 4 like 2; coisogenic strain: Morf4l2
Proper citation: RRID:IMSR_GPT:T044551 Copy
https://www.jax.org/strain/038824
Source Database: JAX Mice and Services
Affected Genes: myosin; heavy polypeptide 11; smooth muscle
Genomic Alteration: endonuclease-mediated mutation 2; Jifeng Zhang
Availability: live
Notes: gene symbol note: myosin; heavy polypeptide 11; smooth muscle; coisogenic strain|mutant strain: Myh11
Proper citation: RRID:IMSR_JAX:038824 Copy
https://www.jax.org/strain/039001
Source Database: JAX Mice and Services
Affected Genes: N-sulfoglucosamine sulfohydrolase (sulfamidase)|interleukin 2 receptor; gamma chain|recombination activating gene 2|CD47 antigen (Rh-related antigen; integrin-associated signal transducer)
Genomic Alteration: mucopolysaccharidosis IIIA|targeted mutation 1; Warren J Leonard|targeted mutation 1; Frederick W Alt|targeted mutation 1; Frederik P Lindberg
Availability: live
Notes: gene symbol note: N-sulfoglucosamine sulfohydrolase (sulfamidase)|interleukin 2 receptor; gamma chain|recombination activating gene 2|CD47 antigen (Rh-related antigen; integrin-associated signal transducer); mutant strain|congenic strain: Sgsh|Il2rg|Rag2|Cd47
Proper citation: RRID:IMSR_JAX:039001 Copy
https://www.jax.org/strain/038919
Source Database: JAX Mice and Services
Affected Genes: interspecies replacement; human Chr 19; Michael Koob 2
Genomic Alteration: interspecies replacement; human Chr 19; Michael Koob 2
Availability: live
Synonyms: B6J.B6N-Tc(HSA19*APOE_i4)1Mdk/J
Notes: gene symbol note: interspecies replacement; human Chr 19; Michael Koob 2; mutant strain|congenic strain: Isr(HSA19;APOE_i4)2Mdk
Proper citation: RRID:IMSR_JAX:038919 Copy
https://www.jax.org/strain/038812
Source Database: JAX Mice and Services
Affected Genes: coagulation factor XII (Hageman factor)
Genomic Alteration: targeted mutation 1; Francis J Castellino
Availability: live
Notes: gene symbol note: coagulation factor XII (Hageman factor); mutant strain|congenic strain: F12
Proper citation: RRID:IMSR_JAX:038812 Copy
https://www.jax.org/strain/038813
Source Database: JAX Mice and Services
Affected Genes: fibrinogen gamma chain
Genomic Alteration: targeted mutation 1; Francis J Castellino
Availability: live
Notes: gene symbol note: fibrinogen gamma chain; mutant strain|congenic strain: Fgg
Proper citation: RRID:IMSR_JAX:038813 Copy
https://www.jax.org/strain/038929
Source Database: JAX Mice and Services
Affected Genes: retinoid X receptor gamma|retinoic acid receptor; beta
Genomic Alteration: endonuclease-mediated mutation 1; Nenad Sestan
Availability: live
Notes: gene symbol note: retinoid X receptor gamma|retinoic acid receptor; beta; mutant stock: Rxrg|Rarb
Proper citation: RRID:IMSR_JAX:038929 Copy
https://www.jax.org/strain/039033
Source Database: JAX Mice and Services
Affected Genes: HtrA serine peptidase 1
Genomic Alteration: targeted mutation 1.2; Josephine Hoh
Availability: live
Notes: gene symbol note: HtrA serine peptidase 1; coisogenic strain|mutant strain: Htra1
Proper citation: RRID:IMSR_JAX:039033 Copy
https://www.jax.org/strain/039032
Source Database: JAX Mice and Services
Affected Genes: HtrA serine peptidase 2
Genomic Alteration: targeted mutation 1.1; Josephine Hoh
Availability: live
Notes: gene symbol note: HtrA serine peptidase 2; coisogenic strain|mutant strain: Htra2
Proper citation: RRID:IMSR_JAX:039032 Copy
https://www.jax.org/strain/038908
Source Database: JAX Mice and Services
Affected Genes: interspecies replacement; human Chr 17; Michael Koob 2|amyloid beta precursor protein
Genomic Alteration: interspecies replacement; human Chr 17; Michael Koob 2|endonuclease-mediated mutation 1; MODEL-AD Center
Availability: live
Synonyms: B6.Cg-Tc(HSA17)2Mdk App
Notes: gene symbol note: interspecies replacement; human Chr 17; Michael Koob 2|amyloid beta precursor protein; mutant strain|congenic strain: Isr(HSA17)2Mdk|App
Proper citation: RRID:IMSR_JAX:038908 Copy
https://www.jax.org/strain/039199
Source Database: JAX Mice and Services
Affected Genes: transgene insertion 4.2.28; Myriam Hemberger
Genomic Alteration: transgene insertion 4.2.28; Myriam Hemberger
Availability: live
Synonyms: B6N.Cg-Tg(Sox2-flpo)4.2.28Mhem/J
Notes: gene symbol note: transgene insertion 4.2.28; Myriam Hemberger; mutant strain: Tg(Sox2-flpo)4.2.28Mhem
Proper citation: RRID:IMSR_JAX:039199 Copy
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