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Integrated Animals is a virtual database currently indexing available animal strains and mutants from: AGSC (Ambystoma), BCBC (mice), BDSC (flies), European Xenopus Resource Center (frog), The National Xenopus Resource (frog), Xenopus Express (frog), CWRU Cystic Fibrosis Mouse Models (mice), DGGR (flies), FlyBase (flies), IMSR (mice), MGI (mice), MMRRC (mice), NSRRC (pig), RGD (rats), Sperm Stem Cell Libraries for Biological Research (rats), Tetrahymena Stock Center (Tetrahymena), WormBase (worms), XGSC (Xiphophorus), ZFIN (zebrafish), and ZIRC (zebrafish). Note, the IMSR data is linked, but users may need to re-execute the search if the top mouse is not returned properly.
Note: BCBC is no longer in service, so the links may not be functional.
http://www.wormbase.org/db/get?name=WBStrain00008307
Source Database: WormBase (WB)
Availability: available
Synonyms: goeIs22.
Alternate IDs: WB-STRAIN:HBR205, CGC_HBR205
Notes: goeIs22 [mec-4p::SL1::GCaMP3.35::SL2::mKate2::unc-54 3'UTR + unc-119(+)]. Reporter allows visualization of several mechanosensitive neurons. Reference: Schwarz J & Bringmann H. PLoS One. 2013 Sep 20;8(9):e75853.
Proper citation: RRID:WB-STRAIN:WBStrain00008307 Copy
http://www.wormbase.org/db/get?name=WBStrain00008308
Source Database: WormBase (WB)
Affected Genes: WBGene00019424(aptf-1)
Genomic Alteration: WBGene00019424(aptf-1)
Availability: available
Source References: PMID:32811254, PMID:36652499
Synonyms: aptf-1(gk794) II.
Alternate IDs: WB-STRAIN:HBR227, CGC_HBR227
Notes: Complete lack of behavioral quiescence during sleep. References: Turek et al. Current Biology, 2013, 23, 2215-2223. Turek et al. eLife 2016;5:e12499.|"WBStrain mapped, WBPaper00060107 added based on AFP_Strain data."
Proper citation: RRID:WB-STRAIN:WBStrain00008308 Copy
http://www.wormbase.org/db/get?name=WBStrain00008309
Source Database: WormBase (WB)
Affected Genes: WBGene00019424(aptf-1)
Genomic Alteration: WBGene00019424(aptf-1)
Availability: available
Source References: PMID:32811254, PMID:40114851
Synonyms: aptf-1(tm3287) II.
Alternate IDs: WB-STRAIN:HBR232, CGC_HBR232
Notes: Complete lack of behavioral quiescence during sleep. Reference: Turek et al. Current Biology, 2013, 23, 2215-2223.|"WBStrain mapped, WBPaper00060107 added based on AFP_Strain data."
Proper citation: RRID:WB-STRAIN:WBStrain00008309 Copy
http://www.wormbase.org/db/get?name=WBStrain00008390
Source Database: WormBase (WB)
Affected Genes: WBGene00006828(unc-100)
Genomic Alteration: WBGene00006828(unc-100)
Availability: available
Source References: PMID:7348600
Synonyms: unc-100(su115) I.
Alternate IDs: WB-STRAIN:HE115, CGC_HE115
Notes: Made_by: Zengel J|"Slow. Slightly Dpy. Recessive. Grows fairly well. Body Muscle abnormal. Sarcomeres faint."
Proper citation: RRID:WB-STRAIN:WBStrain00008390 Copy
http://www.wormbase.org/db/get?name=WBStrain00008391
Source Database: WormBase (WB)
Affected Genes: WBGene00006827(unc-98)
Genomic Alteration: WBGene00006827(unc-98)
Availability: available
Source References: PMID:7348600
Synonyms: unc-98(su130) X.
Alternate IDs: WB-STRAIN:HE130, CGC_HE130
Notes: Made_by: Zengel J|"Movement WT. Body muscle abnormal."
Proper citation: RRID:WB-STRAIN:WBStrain00008391 Copy
http://www.wormbase.org/db/get?name=WBStrain00008392
Source Database: WormBase (WB)
Affected Genes: WBGene00006764(unc-27)
Genomic Alteration: WBGene00006764(unc-27)
Availability: available
Synonyms: unc-27(su142) X.
Alternate IDs: WB-STRAIN:HE142, CGC_HE142
Notes: Made_by: Zengel J|"Slow moving Unc. Semi-dominant. Body muscle abnormal. Slightly small."
Proper citation: RRID:WB-STRAIN:WBStrain00008392 Copy
http://www.wormbase.org/db/get?name=WBStrain00008393
Source Database: WormBase (WB)
Affected Genes: WBGene00006825(unc-96)
Genomic Alteration: WBGene00006825(unc-96)
Availability: available
Source References: PMID:7348600
Synonyms: unc-96(su151) X.
Alternate IDs: WB-STRAIN:HE151, CGC_HE151
Notes: Made_by: Zengel J|"Movement WT. Body muscle abnormal."
Proper citation: RRID:WB-STRAIN:WBStrain00008393 Copy
http://www.wormbase.org/db/get?name=WBStrain00008396
Source Database: WormBase (WB)
Affected Genes: WBGene00006787(unc-52)
Genomic Alteration: WBGene00006787(unc-52)
Availability: available
Source References: PMID:7348600
Synonyms: unc-52(su200) II.
Alternate IDs: WB-STRAIN:HE200, CGC_HE200
Notes: Made_by:
Proper citation: RRID:WB-STRAIN:WBStrain00008396 Copy
http://www.wormbase.org/db/get?name=WBStrain00008311
Source Database: WormBase (WB)
Affected Genes: WBGene00001454(flp-11)
Genomic Alteration: WBGene00001454(flp-11)
Availability: available
Source References: PMID:36652499, PMID:37155851
Synonyms: flp-11(tm2706) X.
Alternate IDs: WB-STRAIN:HBR507, CGC_HBR507
Notes: 70% reduction of behavioral quiescence during sleep. Reference: Turek et al. eLife 2016;5:e12499.
Proper citation: RRID:WB-STRAIN:WBStrain00008311 Copy
http://www.wormbase.org/db/get?name=WBStrain00008312
Source Database: WormBase (WB)
Availability: available
Synonyms: goeIs102.
Alternate IDs: WB-STRAIN:HBR546, CGC_HBR546
Notes: goeIs102 [aptf-1 5'UTR::ChR2::mKate2::aptf-1 3'UTR + unc-119(+)]. Superficially wild-type. This strain carries an optogenetic transgene that can be used to send worms to sleep immediately at any given time point. Reference: Turek M, et al. Curr Biol. 2013 Nov 18;23(22):2215-2223.|"goeIs102 [aptf-1 5'UTR::ChR2::mKate2::aptf-1 3'UTR + unc-119(+)]. Superficially wild-type. This strain carries an optogenetic transgene, which allows to send worms to sleep immediately at any given time point. Reference: Turek M, et al. Curr Biol. 2013 Nov 18;23(22):2215-2223."
Proper citation: RRID:WB-STRAIN:WBStrain00008312 Copy
http://www.wormbase.org/db/get?name=WBStrain00008313
Source Database: WormBase (WB)
Availability: available
Synonyms: C10C6.7(goe3) IV.
Alternate IDs: WB-STRAIN:HBR762, CGC_HBR762
Notes: goe3 is a 25 bp deletion in the second exon causing a frame shift and presumptive molecular null allele. sgRNA target sequence: GTTATGGTGAGAAGGAAAGCtgg Reference: Turek et al. eLife 2016;5:e12499.|"Made_by: Lewandrowski & Turek"
Proper citation: RRID:WB-STRAIN:WBStrain00008313 Copy
http://www.wormbase.org/db/get?name=WBStrain00008383
Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: available
Synonyms: hwSi3 II; unc-119(ed9) III.
Alternate IDs: WB-STRAIN:HCC21, CGC_HCC21
Notes: hwSi3 [pie-1p::GFP::mex-3::pie-1 3'UTR + unc-119(+)] II. Worms are healthiest at 15C. Shift to 25C overnight to increase brightness of GFP. Mos1-mediated single-copy insertion (MosSCI) into EG4322. GFP-tagged transgene expressing full-length MEX-3 uniformly throughout oocytes and early embryos through the 4-cell stage. GFP::MEX-3 then mirrors endogenous MEX-3, disappearing from somatic cells by about the 12-cell stage. Also detected in P granules. GFP::MEX-3 can replace endogenous MEX-3. Reference: Huang NN & Hunter CP. Gene. 2015 Jan 10;554(2):160-73.
Proper citation: RRID:WB-STRAIN:WBStrain00008383 Copy
http://www.wormbase.org/db/get?name=WBStrain00008386
Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: available
Source References: PMID:33440146, PMID:37453426
Synonyms: unc-119(ed3) III; uocIs1.
Alternate IDs: WB-STRAIN:HCL67, CGC_HCL67
Notes: uocIs1 [eft-3p::Cas9(dpiRNA)::tbb-2 3' UTR + unc-119(+)]. Cas9 is optimized to remove all piRNA sites. Cas9 is expressed in the germline. Reference: Zhang D, et al. Science. 2018 Feb 2;359(6375):587-592.
Proper citation: RRID:WB-STRAIN:WBStrain00008386 Copy
http://www.wormbase.org/db/get?name=WBStrain00008389
Source Database: WormBase (WB)
Affected Genes: WBGene00004879(smg-1)|WBGene00006826(unc-97)
Genomic Alteration: WBGene00004879(smg-1), WBGene00006826(unc-97)
Availability: available
Source References: PMID:7348600
Synonyms: smg-1(re1) I; unc-97(su110) X.
Alternate IDs: WB-STRAIN:HE110, CGC_HE110
Notes: Variable phenotype-WT when relaxed. Paralyzed. Dave Reiner identified smg-1(re1) in this strain.
Proper citation: RRID:WB-STRAIN:WBStrain00008389 Copy
http://www.wormbase.org/db/get?name=WBStrain00008334
Source Database: WormBase (WB)
Affected Genes: WBGene00004796(sid-2)
Genomic Alteration: WBGene00004796(sid-2)
Availability: available
Source References: PMID:38547071
Synonyms: ccIs4251 [(pSAK2) Pmyo-3::GFP::LacZ::NLS + (pSAK4) Pmyo-3::mitochondrial GFP + dpy-20(+)] I; qtIs3 [Pmyo-2::GFP dsRNA hairpin] sid-2(qt42) III; mIs11 [Pmyo-2::GFP + Ppes-10::GFP + gut-promoter::GFP] IV
Alternate IDs: WB-STRAIN:HC271, CGC_HC271
Notes: ccIs4251 [(pSAK2) myo-3p::GFP::LacZ::NLS + (pSAK4) myo-3p::mitochondrial GFP + dpy-20(+)] I. qtIs3 [myo-2p::GFP dsRNA hairpin]. mIs11 [myo-2p::GFP + pes-10p::GFP + gut-promoter::GFP]. GFP expression in 4-cell embryos, pharyngeal muscle and gut. Resistant to systemic RNAi by feeding only.
Proper citation: RRID:WB-STRAIN:WBStrain00008334 Copy
http://www.wormbase.org/db/get?name=WBStrain00008314
Source Database: WormBase (WB)
Availability: available
Synonyms: C10C6.7(goe5) IV.
Alternate IDs: WB-STRAIN:HBR764, CGC_HBR764
Notes: goe5 is a 4 bp deletion in the second exon causing a frame shift and presumptive molecular null allele. sgRNA target sequence: GTTATGGTGAGAAGGAAAGCtgg Reference: Turek et al. eLife 2016;5:e12499.|"Made_by: Lewandrowski & Turek"
Proper citation: RRID:WB-STRAIN:WBStrain00008314 Copy
http://www.wormbase.org/db/get?name=WBStrain00008315
Source Database: WormBase (WB)
Affected Genes: WBGene00002988(lim-6)
Genomic Alteration: WBGene00002988(lim-6)
Availability: available
Synonyms: lim-6(tm4836) X.
Alternate IDs: WB-STRAIN:HBR914, CGC_HBR914
Notes: Complete lack of behavioral quiescence during sleep. Reference: Turek et al. eLife 2016;5:e12499.
Proper citation: RRID:WB-STRAIN:WBStrain00008315 Copy
http://www.wormbase.org/db/get?name=WBStrain00008316
Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: available
Synonyms: unc-119(ed3) III; goeEx361.
Alternate IDs: WB-STRAIN:HBR986, CGC_HBR986
Notes: goeEx361 [ceh-24p::ReaChr::mKate2::unc-54 3'UTR + unc-119(+)]. Pick non-Unc to maintain. Reporter expresses ReaChr with expression control mKate2. Reference: Schwarz J & Bringmann H. eLife 2017;10.7554/eLife.24846.
Proper citation: RRID:WB-STRAIN:WBStrain00008316 Copy
http://www.wormbase.org/db/get?name=WBStrain00008319
Source Database: WormBase (WB)
Availability: available
Synonyms: goeIs247.
Alternate IDs: WB-STRAIN:HBR1077, CGC_HBR1077
Notes: goeIs247 [ceh-24p::GCaMP6s::mKate2::unc-54 3'UTR + unc-119(+)]. Reporter expresses calcium sensor GCaMP6s with expression control mKate2. Reference: Schwarz J & Bringmann H. eLife 2017;10.7554/eLife.24846.
Proper citation: RRID:WB-STRAIN:WBStrain00008319 Copy
http://www.wormbase.org/db/get?name=WBStrain00008320
Source Database: WormBase (WB)
Availability: available
Synonyms: goeIs288.
Alternate IDs: WB-STRAIN:HBR1261, CGC_HBR1261
Notes: goeIs288 [flp-11p::mKate2::unc-54 3'UTR + unc-119(+)]. Low copy number insertion. Integration site unknown, but likely not in LG II. Reference: Turek et al. eLife 2016;5:e12499.
Proper citation: RRID:WB-STRAIN:WBStrain00008320 Copy
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