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Integrated Animals is a virtual database currently indexing available animal strains and mutants from: AGSC (Ambystoma), BCBC (mice), BDSC (flies), European Xenopus Resource Center (frog), The National Xenopus Resource (frog), Xenopus Express (frog), CWRU Cystic Fibrosis Mouse Models (mice), DGGR (flies), FlyBase (flies), IMSR (mice), MGI (mice), MMRRC (mice), NSRRC (pig), RGD (rats), Sperm Stem Cell Libraries for Biological Research (rats), Tetrahymena Stock Center (Tetrahymena), WormBase (worms), XGSC (Xiphophorus), ZFIN (zebrafish), and ZIRC (zebrafish). Note, the IMSR data is linked, but users may need to re-execute the search if the top mouse is not returned properly.
Note: BCBC is no longer in service, so the links may not be functional.
http://www.wormbase.org/db/get?name=WBStrain00050698
Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: unknown
Synonyms: unc-119(ed3) III; goeIs257.
Notes: goeIs257 [nas- 38p::d1mGFP::nas-38 3'UTR + unc-119(+)]. Destabilized GFP expressed from the nas-38 promoter; especially visible in hypodermis and excretory system. Reference: Sinner MP, et al. Curr Biol. 2021 Feb 8;31(3):564-577.e12. PMID: 33259791|"Made_by: Florentin Masurat"
Proper citation: RRID:WB-STRAIN:WBStrain00050698 Copy
http://www.wormbase.org/db/get?name=WBStrain00050761
Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)|WBGene00009163(drsh-1)|WBGene00011908(pash-1)
Genomic Alteration: WBGene00006843(unc-119), WBGene00009163(drsh-1), WBGene00011908(pash-1)
Availability: unknown
Synonyms: drsh-1(luc82[myc::AID::3XFLAG::4xGGSG::drsh-1::4xGGSG::3xFLAG::AID::myc]) pash-1(luc71[pash-1::2xGGSG::3xFLAG::AID::myc]) I; ieSi57 II; unc-119(ed3) III; ieSi38 IV; lucIs20; lucIs24.
Notes: ieSi57 [eft-3p::TIR1::mRuby::unc-54 3'UTR + Cbr-unc-119(+)] II. ieSi38 [sun-1p::TIR1::mRuby::sun-1 3'UTR + Cbr-unc-119(+)] IV. lucIs20 [mir-35p::mirtron-35 + myo-2::mCherry]. lucIs24 [mir-52p::mirtron-51 + elt-2::dsRed + myo-2::mCherry]. Endogenous drsh-1 tagged at both N- and C-termini with the auxin-inducible-degron (AID) peptide. Endogenous pash-1 tagged with the AID peptide at the C-terminus. Strain expresses modified Arabidopsis thaliana TIR1 tagged with mRuby in soma and germline. In addition, strain expresses mirtron-versions of mir-35 and mir-51, which are processed independently of Drosha and Pasha. miRNA biogenesis can be stringently inhibited via simultaneous removal of Drosha and Pasha, causing absence of all canonical miRNAs and embryonic lethality upon Auxin treatment. Reference: Dexheimer, PJ, et al. Curr Biol. 2020. in press.|"Made_by: Philipp Dexheimer"
Proper citation: RRID:WB-STRAIN:WBStrain00050761 Copy
http://www.wormbase.org/db/get?name=WBStrain00050748
Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: unknown
Synonyms: lucSi100 II; unc-119(ed3) III.
Notes: lucSi100 [hsp16.41::vhhGFP4::zif-1::SL2::mCherry::his-11::tbb-2 3'UTR] II. Superficially wild-type morphology. Single-copy insertion of a GFP-nanobody::zif-1 fusion transgene under a heat-shock promoter for timely controlled degradation of GFP-tagged proteins (Wang et al. (2017). A toolkit for GFP-mediated tissue-specific protein degradation in C. elegans. Development 144, 2694-2701.)
Proper citation: RRID:WB-STRAIN:WBStrain00050748 Copy
http://www.wormbase.org/db/get?name=WBStrain00050747
Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)|WBGene00011908(pash-1)
Genomic Alteration: WBGene00006843(unc-119), WBGene00011908(pash-1)
Availability: unknown
Synonyms: pash-1(luc71[pash-1::2xGGSG::3xFLAG::AID::myc]) I; ieSi57 II; unc-119(ed3) III; ieSi38 IV.
Notes: ieSi57 [eft-3p::TIR1::mRuby::unc-54 3'UTR + Cbr-unc-119(+)] II. ieSi38 [sun-1p::TIR1::mRuby::sun-1 3'UTR + Cbr-unc-119(+)] IV. Endogenous pash-1 tagged with the auxin-inducible-degron (AID) peptide at the C-terminus. Strain expresses modified Arabidopsis thaliana TIR1 tagged with mRuby in germ line and soma. Animals are superficially wild-type; addition of auxin induces embryonic lethality and larval arrest phenotypes. Reference: Dexheimer, PJ, et al. Curr Biol. 2020. in press.|"Made_by: Philipp Dexheimer"
Proper citation: RRID:WB-STRAIN:WBStrain00050747 Copy
http://www.wormbase.org/db/get?name=WBStrain00040001
Source Database: WormBase (WB)
Affected Genes: WBGene00001815(hmt-1)|WBGene00006843(unc-119)
Genomic Alteration: WBGene00001815(hmt-1), WBGene00006843(unc-119)
Availability: available
Synonyms: arIs37 I; unc-119(ed3) hmt-1(gk161) III; cdIs32.
Alternate IDs: WB-STRAIN:VF14, CGC_VF14
Notes: arIs37 [myo-3p::ssGFP + dpy-20(+)] I. cdIs32 [unc-122p::DT-A(E148D) + myo-2p::GFP + unc-119(+)]. Hypersensitive to cadmium. Lacks coelomocytes and accumulates GFP in pseudocoelome. Maintain under normal conditions. Reference: Schwartz MS, et al., PLoS One. 2010 Mar 5;5(3):e9564.|"Made_by: Joe Benci"
Proper citation: RRID:WB-STRAIN:WBStrain00040001 Copy
http://www.wormbase.org/db/get?name=WBStrain00039996
Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: available
Synonyms: unc-119(ed3) III; gfEx1.
Alternate IDs: WB-STRAIN:VF1, CGC_VF1
Notes: gfEx1 [hmt-1p::GFP + unc-119(+)]. Maintain under normal conditions. GFP expression detected in Intestinal cells, terminal pharyngeal bulb, coelomocytes, and head & tail neurons. Reference: Schwartz MS, et al., PLoS One. 2010 Mar 5;5(3):e9564.
Proper citation: RRID:WB-STRAIN:WBStrain00039996 Copy
http://www.wormbase.org/db/get?name=WBStrain00040079
Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: available
Synonyms: unc-119(ed3) III; wwEx34.
Alternate IDs: WB-STRAIN:VL1, CGC_VL1
Notes: wwEx34 contains [hlh-31::GFP + unc-119(+)]. Trangenic animals are superficially wild-type. Maintain by picking GFP+.
Proper citation: RRID:WB-STRAIN:WBStrain00040079 Copy
http://www.wormbase.org/db/get?name=WBStrain00040090
Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: available
Synonyms: unc-119(ed3) III; wwEx44.
Alternate IDs: WB-STRAIN:VL19, CGC_VL19
Notes: wwEx44 [hlh-33::GFP + unc-119(+)]. Superficially wildtype. Grove C. A., De Masi F., et al (2009) Cell 138(2); 314-327.
Proper citation: RRID:WB-STRAIN:WBStrain00040090 Copy
http://www.wormbase.org/db/get?name=WBStrain00040087
Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: available
Synonyms: unc-119(ed3) III; wwEx41.
Alternate IDs: WB-STRAIN:VL10, CGC_VL10
Notes: wwEx41 [hlh-13::GFP + unc-119(+)]. Superficially wildtype. Grove C. A., De Masi F., et al (2009) Cell 138(2); 314-327.
Proper citation: RRID:WB-STRAIN:WBStrain00040087 Copy
http://www.wormbase.org/db/get?name=WBStrain00040088
Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: available
Synonyms: unc-119(ed3) III; wwEx42.
Alternate IDs: WB-STRAIN:VL12, CGC_VL12
Notes: wwEx42 [hlh-15::GFP + unc-119(+)]. Superficially wildtype. Grove C. A., De Masi F., et al (2009) Cell 138(2); 314-327.
Proper citation: RRID:WB-STRAIN:WBStrain00040088 Copy
http://www.wormbase.org/db/get?name=WBStrain00040082
Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: available
Synonyms: unc-119(ed3) III; wwEx37.
Alternate IDs: WB-STRAIN:VL4, CGC_VL4
Notes: wwEx37 [ngn-1::GFP + unc-119(+)]. Superficially wildtype. Grove C. A., De Masi F., et al (2009) Cell 138(2); 314-327.
Proper citation: RRID:WB-STRAIN:WBStrain00040082 Copy
http://www.wormbase.org/db/get?name=WBStrain00040084
Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: available
Synonyms: unc-119(ed3) III; wwEx39.
Alternate IDs: WB-STRAIN:VL6, CGC_VL6
Notes: wwEx39 [hlh-32::GFP + unc-119(+)]. Superficially wildtype. Grove C. A., De Masi F., et al (2009) Cell 138(2); 314-327.
Proper citation: RRID:WB-STRAIN:WBStrain00040084 Copy
http://www.wormbase.org/db/get?name=WBStrain00040006
Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: unknown
Synonyms: EMPTY
Alternate IDs: WB-STRAIN:VH41
Notes: EMPTY
Proper citation: RRID:WB-STRAIN:WBStrain00040006 Copy
http://www.wormbase.org/db/get?name=WBStrain00040100
Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: available
Synonyms: unc-119(ed3) III; wwEx51.
Alternate IDs: WB-STRAIN:VL78, CGC_VL78
Notes: wwEx51 contains [hlh-1::GFP + unc-119(+)]. Trangenic animals are superficially wild-type. Maintain by picking GFP+.
Proper citation: RRID:WB-STRAIN:WBStrain00040100 Copy
http://www.wormbase.org/db/get?name=WBStrain00040101
Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: available
Synonyms: unc-119(ed3) III; wwIs10.
Alternate IDs: WB-STRAIN:VL99, CGC_VL99
Notes: Made_by: N Martinez/M Ow|"wwIs10 [mir-45p::GFP + unc-119(+)]. Wild type."
Proper citation: RRID:WB-STRAIN:WBStrain00040101 Copy
http://www.wormbase.org/db/get?name=WBStrain00040030
Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: available
Synonyms: unc-119(ed3) III; pmcIs1.
Alternate IDs: WB-STRAIN:VIG3, CGC_VIG3
Notes: pmcIs1 [ant-1.1p::ant-1.1::GFP + unc-119(+)]. Expression of ant-1.1::GFP under ant-1.1 promotor (Farina et al., Dev Dyn 2008) in most tissues including the gonads and in the spermatozoa. GFP intensity is low and unstable. GFP positive worms should be selected under fluorescence microscope. ant-1.1::GFP expression seems to be more stable when worms are grown at 24C and in the dark. Reference: Al Rawi S, et al. Science. 2011 Nov 25;334(6059):1144-7.
Proper citation: RRID:WB-STRAIN:WBStrain00040030 Copy
http://www.wormbase.org/db/get?name=WBStrain00040095
Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: available
Synonyms: unc-119(ed3) III; wwIs1.
Alternate IDs: WB-STRAIN:VL43, CGC_VL43
Notes: wwIs1[mdl-1::GFP + unc-119(+)]. Worms are non-Unc.
Proper citation: RRID:WB-STRAIN:WBStrain00040095 Copy
http://www.wormbase.org/db/get?name=WBStrain00040016
Source Database: WormBase (WB)
Affected Genes: WBGene00003004(lin-15)|WBGene00006843(unc-119)|WBGene00023497(lin-15B)|WBGene00045274(nre-1)
Genomic Alteration: WBGene00003004(lin-15), WBGene00006843(unc-119), WBGene00023497(lin-15B), WBGene00045274(nre-1)
Availability: available
Source References: PMID:33634121, PMID:37432924
Synonyms: rhIs13 V; nre-1(hd20) lin-15B(hd126) X.
Alternate IDs: WB-STRAIN:VH624, CGC_VH624
Notes: rhIs13 [unc-119::GFP + dpy-20(+)]. RNAi hypersensitive, effective RNAi in the nervous system. unc-119::GFP in neurons is almost completely suppressed on anti-GFP RNAi plates. Reduced progeny at 25C (almost sterile). nre-1(hd20) and lin-15B(hd126) seem very closely linked. Maintain at 15C or 20C.
Proper citation: RRID:WB-STRAIN:WBStrain00040016 Copy
http://www.wormbase.org/db/get?name=WBStrain00040117
Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: available
Synonyms: unc-119(ed3) III; wwIs18.
Alternate IDs: WB-STRAIN:VL412, CGC_VL412
Notes: Made_by: N Martinez/M Ow|"wwIs18 [mir-79p::GFP + unc-119(+)]. Wild type."
Proper citation: RRID:WB-STRAIN:WBStrain00040117 Copy
http://www.wormbase.org/db/get?name=WBStrain00040115
Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: available
Synonyms: unc-119(ed3) III; wwEx31.
Alternate IDs: WB-STRAIN:VL397, CGC_VL397
Notes: Made_by: N Martinez/M Ow|"wwEx31 [mir-268p::GFP + unc-119(+)]. Maintain by picking WT."
Proper citation: RRID:WB-STRAIN:WBStrain00040115 Copy
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