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Integrated Animals is a virtual database currently indexing available animal strains and mutants from: AGSC (Ambystoma), BCBC (mice), BDSC (flies), European Xenopus Resource Center (frog), The National Xenopus Resource (frog), Xenopus Express (frog), CWRU Cystic Fibrosis Mouse Models (mice), DGGR (flies), FlyBase (flies), IMSR (mice), MGI (mice), MMRRC (mice), NSRRC (pig), RGD (rats), Sperm Stem Cell Libraries for Biological Research (rats), Tetrahymena Stock Center (Tetrahymena), WormBase (worms), XGSC (Xiphophorus), ZFIN (zebrafish), and ZIRC (zebrafish). Note, the IMSR data is linked, but users may need to re-execute the search if the top mouse is not returned properly.
Note: BCBC is no longer in service, so the links may not be functional.
http://www.wormbase.org/db/get?name=WBStrain00054981
Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: unknown
Synonyms: ltSi220 I; ltSi1232 II; unc-119(ed3) III.
Notes: ltSi220 [mex-5p::GFP::tbb-2::operon-linker::mCherry::his-11 + Cbr-unc-119(+)] I. ltSi1232 [spd-2p::spd-5(S170A T178A T198A)::spd-5 3'UTR + Cbr-unc-119(+)] II. mCherry-labeled histones. GFP-labeled microtubules. Reference: Ohta M, et al. J Cell Biol. 2021 Feb 1;220(2):e202009083. doi: 10.1083/jcb.202009083. PMID: 33399854.
Proper citation: RRID:WB-STRAIN:WBStrain00054981 Copy
http://www.wormbase.org/db/get?name=WBStrain00054983
Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: unknown
Synonyms: ltSi220 I; ltSi1561 II; unc-119(ed3) III.
Notes: ltSi220 [mex-5p::GFP::tbb-2::operon-linker::mCherry::his-11 + Cbr-unc-119(+)] I. ltSi1561 [spd-2p::spd-5(S170A T178A T198A S653A S658A)::spd-5 3'UTR + Cbr-unc-119(+)] II. mCherry-labeled histones. GFP-labeled microtubules. Reference: Ohta M, et al. J Cell Biol. 2021 Feb 1;220(2):e202009083. doi: 10.1083/jcb.202009083. PMID: 33399854.
Proper citation: RRID:WB-STRAIN:WBStrain00054983 Copy
http://www.wormbase.org/db/get?name=WBStrain00054987
Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: unknown
Synonyms: ltSi264 II; unc-119(ed3) III.
Notes: ltSi264 [bub-1p::bub-1(re-encoded)::RFP + Cbr-unc-119(+)] II. BUB-1::RFP has been re-coded to be knl-1(RNAi) resistant. Reference: Pelisch F, et al. Mol Cell. 2017 Jan 5;65(1):66-77. doi: 10.1016/j.molcel.2016.11.001. PMID: 27939944|"Made_by: Arshad Desai lab"
Proper citation: RRID:WB-STRAIN:WBStrain00054987 Copy
http://www.wormbase.org/db/get?name=WBStrain00054966
Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: unknown
Synonyms: ltSi597 I; unc-119(ed3) III.
Notes: ltSi597 [knl-1p::knl-1::mCherry::knl-1 3'UTR Cbr-unc-119(+)] I. mCherry labeled KNL-1. Reference: Hattersley et al., Dev Cell 2016 Sep 12;38(5):463-77. doi: 10.1016/j.devcel.2016.08.006. PMID: 27623381|"Made_by: Arshad Desai lab"
Proper citation: RRID:WB-STRAIN:WBStrain00054966 Copy
http://www.wormbase.org/db/get?name=WBStrain00054968
Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: unknown
Synonyms: ltSi569 I; ltSi1141 II; unc-119(ed3) III.
Notes: ltSi569 [CEOP3608 tbg-1::mCherry + Cbr-unc-119(+)] inserted into oxTi185 [ttTi5605 + NeoR(+) + unc-18(+)] I. ltSi1141 [spd-2p::gfp::spd-5(re-encoded) + Cbr-unc-119(+)] II. Re-encoded spd-5 is siRNA-resistant. mCherry-labeled gamma tubulin. GFP-labeled centrioles. Reference: Woodruff JB, et al. Science. 2015 May 15;348(6236):808-12. doi: 10.1126/science.aaa3923. PMID: 25977552
Proper citation: RRID:WB-STRAIN:WBStrain00054968 Copy
http://www.wormbase.org/db/get?name=WBStrain00047202
Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: unknown
Source References: PMID:32149606
Synonyms: adeIs1 II; unc-119(ed3) III; ltIs37 IV.
Notes: adeIs1 [mex-5::spd-1::GFP + unc-119(+)] II. ltIs37 [pie-1p::mCherry::his-58 + unc-119(+)] IV. Superficially wild-type. SPD-1::GFP and mCherry-tagged histones allow visualisation of chromatin with central spindle/midbody during cell divisions. Reference: Nahaboo W, et al. Mol Biol Cell. 2015 Jun 1;26(11):2020-9.|"adeIs1 [mex-5::spd-1::GFP + unc-119(+)] II. ltIs37 [pie-1p::mCherry::his-58 + unc-119(+)] IV. Superficially wild-type. SPD-1::GFP and mCherry-tagged histones allow visualisation of chromatin with central spindle/midobdy during cell divisions. Reference: Nahaboo W, et al. Mol Biol Cell. 2015 Jun 1;26(11):2020-9."
Proper citation: RRID:WB-STRAIN:WBStrain00047202 Copy
http://www.wormbase.org/db/get?name=WBStrain00047270
Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: unknown
Source References: PMID:37708895, PMID:38746662
Synonyms: egxSi155 II; unc-119(ed3) III.
Notes: egxSi155 [mex-5p::tomm-20::mKate2::pie-1 3UTR + unc-119(+)] II. Superficially wild-type. Stable expression of TOMM-20 tagged with mKate2 on the outer membranes of mitochondria in the germline and embryos. Reference: Fan X, et al. G3 (accepted).|"Made_by: Stephanie Miller"|"Supplementary_genotype egxSi155[mex-5p::tomm-20::mKate2::pie-1 3'UTR + unc-119(+)] II; unc-119(ed3) III"
Proper citation: RRID:WB-STRAIN:WBStrain00047270 Copy
http://www.wormbase.org/db/get?name=WBStrain00047271
Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: unknown
Synonyms: egxSi157 II; unc-119(ed3) III.
Notes: egxSi157 [mex-5p::tomm-20::Dendra2::pie-1 3UTR + unc-119(+)] II. Superficially wild-type. Stable expression of TOMM-20 tagged with photoconvertible Dendra2 on the outer membranes of mitochondria in the germline and embryos. Reference: Fan X, et al. G3 (accepted).|"Made_by: Stephanie Miller"
Proper citation: RRID:WB-STRAIN:WBStrain00047271 Copy
http://www.wormbase.org/db/get?name=WBStrain00047267
Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: unknown
Synonyms: egxSi145 II; unc-119(ed3) III.
Notes: egxSi145 [mex-5p::hsp-3(aa1-19)::halotag::HDEL::pie-1 3UTR + unc-119(+)] II. Superficially wild-type. Stable expression of Halotag in the ER lumen in the germline and embryos. Reference: Fan X, et al. G3 (accepted).|"Made_by: Xintao Fan"
Proper citation: RRID:WB-STRAIN:WBStrain00047267 Copy
http://www.wormbase.org/db/get?name=WBStrain00047268
Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)|WBGene00012354(cox-4)
Genomic Alteration: WBGene00006843(unc-119), WBGene00012354(cox-4)
Availability: unknown
Synonyms: cox-4(zu476[cox-4::eGFP::3XFLAG]) I; egxSi136 II; unc-119(ed3) III.
Notes: egxSi136 [mex-5p::tomm-20::halotag::pie-1 3UTR + unc-119(+)] II. GFP and 3xFLAG tags inserted into endogenous cox-4 locus to create a C-terminal translational GFP fusion. Outer membranes are stably labeled with the TOMM-20::Halotag transgene, and the mitochondria matrix are labeled with COX-4::GFP. Reference: Fan X, et al. G3 (accepted).|"Made_by: Stephanie Miller"
Proper citation: RRID:WB-STRAIN:WBStrain00047268 Copy
http://www.wormbase.org/db/get?name=WBStrain00047269
Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: unknown
Source References: PMID:37708895
Synonyms: egxSi152 II; unc-119(ed3) III.
Notes: egxSi152 [mex-5p: tomm-20::gfp::pie-1 3UTR + unc-119(+)] II. Superficially wild-type. Stable expression of TOMM-20 tagged with GFP on the outer membranes of mitochondria in the germline and embryos. Reference: Fan X, et al. G3 (accepted).|"Made_by: Xintao Fan"|"Supplementary_genotype egxSi152[mex-5p: tomm-20::gfp::pie-1 3UTR + unc-119(+)] II; unc-119(ed3) III"
Proper citation: RRID:WB-STRAIN:WBStrain00047269 Copy
http://www.wormbase.org/db/get?name=WBStrain00047264
Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: unknown
Synonyms: egxSi126 I; unc-119(ed3) III
Notes: egxSi126 [mex-5p::hsp-3(aa1-19)::halotag::HDEL::pie-1 3UTR + unc-119(+)] I. Superficially wild-type. Stable expression of Halotag in the ER lumen in the germline and embryos. Reference: Fan X, et al. G3 (accepted).|"Made_by: Xintao Fan"
Proper citation: RRID:WB-STRAIN:WBStrain00047264 Copy
http://www.wormbase.org/db/get?name=WBStrain00047326
Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: unknown
Synonyms: qSi369 II; unc-119(ed3) III; qSi370 V.
Notes: qSi369 [sygl-1p::24xMS2 loops::3xflag::sygl-1::sygl1 3'UTR]. qSi370 [mex-5p:: MS2 Coat Protein::linker::sfGFP::tbb-2 3' UTR::gpd-2 intergenic sequence::H2B::mCherry::unc-54 3' UTR]. Superficially wild-type with expression of sfGFP and nuclear mCherry in germline. qSi369 and qSi370 constitute an MS2 system which allows live visualization of sygl-1 nascent transcripts in the C. elegans germline in a glp-1 mutant background. qSi370 can be prone to silencing, especially after severe starvation; silencing of GFP or mCherry expression can occur independently of one another. Maintain by picking animals with bright GFP and mCherry expression. Reference: Lee C, et al. Dev Cell. 2019 Aug 19;50(4):426-435.e4.
Proper citation: RRID:WB-STRAIN:WBStrain00047326 Copy
http://www.wormbase.org/db/get?name=WBStrain00047420
Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: unknown
Synonyms: unc-119 (tm4063) III; wgIs797.
Notes: Made_by: DKV/MC|"Mutagen:Particle Bombardment"|"wgIs797 [flt-1::TY1::EGFP::3xFLAG + unc-119(+)]. TY1::EGFP::3xFLAG tag inserted in frame at C-terminus of coding sequence by recombineering. Expression of transgene confirmed by GFP. References: Sarov M, et al. Nat Methods (2006) 10:839-44."
Proper citation: RRID:WB-STRAIN:WBStrain00047420 Copy
http://www.wormbase.org/db/get?name=WBStrain00047422
Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: unknown
Synonyms: unc-119 (tm4063) III; wgIs809.
Notes: Made_by: DKV/MC|"Mutagen:Particle Bombardment"|"wgIs809 [ets-5::TY1::EGFP::3xFLAG + unc-119(+)]. TY1::EGFP::3xFLAG tag inserted in frame at C-terminus of coding sequence by recombineering. Expression of transgene confirmed by GFP. References: Sarov M, et al. Nat Methods (2006) 10:839-44."
Proper citation: RRID:WB-STRAIN:WBStrain00047422 Copy
http://www.wormbase.org/db/get?name=WBStrain00047423
Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: unknown
Synonyms: unc-119 (tm4063) III; wgIs810.
Notes: Made_by: DKV/MC|"Mutagen:Particle Bombardment"|"wgIs810 [C06A6.2::TY1::EGFP::3xFLAG + unc-119(+)]. TY1::EGFP::3xFLAG tag inserted in frame at C-terminus of coding sequence by recombineering. Expression of transgene confirmed by GFP. References: Sarov M, et al. Nat Methods (2006) 10:839-44."
Proper citation: RRID:WB-STRAIN:WBStrain00047423 Copy
http://www.wormbase.org/db/get?name=WBStrain00047435
Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: unknown
Synonyms: unc-119(ed4) III; syEx1539.
Notes: syEx1539 [nhr-246p::GFP + unc-119(+)]. Pick non-Unc to maintain. Dauer decision marker that indicates commitment to dauer formation in intestine and hypodermis. Reference: Shih, PY, et al., Dev Biol. 2019 Jun 23. pii: S0012-1606(18)30788-7.
Proper citation: RRID:WB-STRAIN:WBStrain00047435 Copy
http://www.wormbase.org/db/get?name=WBStrain00047384
Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: unknown
Source References: PMID:32255430, PMID:37728486, PMID:38177158
Synonyms: unc-119(ed3) III; qyIs46.
Notes: qyIs46 [emb-9p::emb-9::mCherry + unc-119(+)] X. Superficially wild-type with very low penetrance (~5%) rupture. Integrated collagen::mCherry reporter. Reference: Ihara S, et al. Nat Cell Biol. 2011 Jun;13(6):641-51.|"Supplementary_genotype [emb-9p::emb-9::mCherry + unc-119(+)] X"
Proper citation: RRID:WB-STRAIN:WBStrain00047384 Copy
http://www.wormbase.org/db/get?name=WBStrain00047419
Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: unknown
Synonyms: unc-119 (tm4063) III; wgIs782.
Notes: Made_by: DKV/MC|"Mutagen:Particle Bombardment"|"wgIs782 [ztf-14::TY1::EGFP::3xFLAG + unc-119(+)]. TY1::EGFP::3xFLAG tag inserted in frame at C-terminus of coding sequence by recombineering. Expression of transgene confirmed by GFP. References: Sarov M, et al. Nat Methods (2006) 10:839-44."
Proper citation: RRID:WB-STRAIN:WBStrain00047419 Copy
http://www.wormbase.org/db/get?name=WBStrain00047346
Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: unknown
Synonyms: rcSi1 II; unc-119(ed3) III.
Notes: rcSi1 [mex-5p::rpt-1::mCherry + unc-119(+)] II. RPT-1::mCherry allows visualization of the proteasome in the germline. Reference: Sampuda KL, et al. BMC Cell Biol. 2017 Apr 19;18(1):18.
Proper citation: RRID:WB-STRAIN:WBStrain00047346 Copy
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