Searching the RRID Resource Information Network
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Integrated Animals is a virtual database currently indexing available animal strains and mutants from: AGSC (Ambystoma), BCBC (mice), BDSC (flies), European Xenopus Resource Center (frog), The National Xenopus Resource (frog), Xenopus Express (frog), CWRU Cystic Fibrosis Mouse Models (mice), DGGR (flies), FlyBase (flies), IMSR (mice), MGI (mice), MMRRC (mice), NSRRC (pig), RGD (rats), Sperm Stem Cell Libraries for Biological Research (rats), Tetrahymena Stock Center (Tetrahymena), WormBase (worms), XGSC (Xiphophorus), ZFIN (zebrafish), and ZIRC (zebrafish). Note, the IMSR data is linked, but users may need to re-execute the search if the top mouse is not returned properly.
Note: BCBC is no longer in service, so the links may not be functional.
| Organism Name | Proper Citation | Species | Synonyms |
Notes |
Phenotype | Affected Gene | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
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NOD.Cg-H2h4 Tg(tetO-Tcra)1Doi/HbmMmmh Resource Report Resource Website |
RRID:MMRRC_037148-MU | Mus musculus | Research areas: Immunology and Inflammation; Mutation Type: Targeted Mutation ; Collection: Mullen | abnormal cytokine secretion [MP:0003009]| thyroid inflammation [MP:0003504]| insulitis [MP:0004031]| decreased susceptibility to autoimmune diabetes [MP:0004804]| periinsulitis [MP:0005580]| decreased physiological sensitivity to xenobiotic [MP:0008874] | ||Tcra| | 037148-MU | Targeted Mutation | Mutant Mouse Resource and Research Center (MMRRC) | MMRRC | PMID:21220693 PMID:23509363 |
MMRRC_37148-MU, MMRRC_037148, MMRRC_37148 | 2026-08-01 05:43:46 | 0 | |||
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C3Fe.B6-Golga3repro27/LincMmjax Resource Report Resource Website |
RRID:MMRRC_037050-JAX | Mus musculus | Research areas: Apoptosis, Cell Biology, Developmental Biology, Models for Human Disease, Reproduction; Mutation Type: chemically induced mutation ; Collection: | impaired fertilization [MP:0000242]| abnormal testis morphology [MP:0001146]| abnormal spermatogenesis [MP:0001156]| male infertility [MP:0001925]| abnormal spermiogenesis [MP:0001932]| asthenozoospermia [MP:0002675]| globozoospermia [MP:0002686]| oligozoospermia [MP:0002687]| decreased testis weight [MP:0004852]| decreased male germ cell number [MP:0004901]| azoospermia [MP:0005159]| teratozoospermia [MP:0005578]| abnormal male germ cell apoptosis [MP:0008280]| absent sperm flagellum [MP:0008545]| detached sperm flagellum [MP:0008893]| abnormal sperm head morphology [MP:0009230]| decreased fertilization frequency [MP:0009647] | Golga3 | 037050-JAX | chemically induced mutation | Mutant Mouse Resource and Research Center (MMRRC) | MMRRC | PMID:23495255 | MMRRC_37050-JAX, MMRRC_037050, MMRRC_375 | 2026-08-01 05:43:49 | 0 | |||
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B6;129S2-Drd3tm1Stl/Mmjax Resource Report Resource Website |
RRID:MMRRC_037114-JAX | Mus musculus | Research areas: Neurobiology, Obesity; Mutation Type: Targeted Mutation ; Collection: | abnormal body water content [MP:0000676]| hyperactivity [MP:0001399]| increased exploration in new environment [MP:0001415]| abnormal cued conditioning behavior [MP:0001454]| abnormal food intake [MP:0005449]| increased susceptibility to weight gain [MP:0005455]| increased percent body fat/body weight [MP:0005458]| increased circulating leptin level [MP:0005669]| abnormal behavioral response to addictive substance [MP:0009748]| increased total body fat amount [MP:0010024] | Drd3 | 037114-JAX | Targeted Mutation | Mutant Mouse Resource and Research Center (MMRRC) | MMRRC | PMID:9354330 | MMRRC_37114-JAX, MMRRC_037114, MMRRC_37114 | 2026-08-01 05:43:49 | 0 | |||
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C57BL/6J-Ank1M1Btlr/Mmmh Resource Report Resource Website |
RRID:MMRRC_037103-MU | Mus musculus | Research areas: Cell Biology, Developmental Biology, Hematology, Models for Human Disease, Research Tools; Mutation Type: chemically induced mutation ; Collection: Beutler Mutagenetix | extramedullary hematopoiesis [MP:0000240]| abnormal spleen morphology [MP:0000689]| enlarged spleen [MP:0000691]| abnormal erythrocyte morphology [MP:0002447]| decreased mean corpuscular volume [MP:0002591]| reticulocytosis [MP:0002640]| spherocytosis [MP:0002812]| microcytosis [MP:0002813]| increased erythrocyte cell number [MP:0003131]| abnormal erythrocyte osmotic lysis [MP:0003657]| increased circulating bilirubin level [MP:0005344]| decreased mean corpuscular hemoglobin [MP:0005562]| increased spleen iron level [MP:0008809]| stomatocytosis [MP:0010074]| hemolysis [MP:0010163]| increased circulating erythropoietin level [MP:0011285] | Ank1 | 037103-MU | chemically induced mutation | Mutant Mouse Resource and Research Center (MMRRC) | MMRRC | PMID:23934996 | MMRRC_37103-MU, MMRRC_037103, MMRRC_3713 | 2026-08-01 05:44:02 | 0 | |||
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B6;129S4-Mns1tm1Jw/Mmjax Resource Report Resource Website 1+ mentions |
RRID:MMRRC_037095-JAX | Mus musculus | Research areas: Cell Biology, Developmental Biology, Models for Human Disease, Reproduction; Mutation Type: Targeted Mutation ; Collection: | hydroencephaly [MP:0001891]| male infertility [MP:0001925]| abnormal epididymis morphology [MP:0002631]| asthenozoospermia [MP:0002675]| oligozoospermia [MP:0002687]| left pulmonary isomerism [MP:0003178]| decreased testis weight [MP:0004852]| abnormal spermatid morphology [MP:0006380]| abnormal sperm flagellum morphology [MP:0008892]| kinked sperm flagellum [MP:0009237]| short sperm flagellum [MP:0009239]| abnormal sperm mitochondrial sheath morphology [MP:0009832]| abnormal sperm axoneme morphology [MP:0009838]| lethality [MP:0010831]| incomplete penetrance [MP:0010854]| lung situs inversus [MP:0011050]| abnormal respiratory motile cilium morphology [MP:0030591] | Mns1 | 037095-JAX | Targeted Mutation | Mutant Mouse Resource and Research Center (MMRRC) | MMRRC | PMID:22396656 | MMRRC_37095-JAX, MMRRC_037095, MMRRC_3795 | 2026-08-01 05:43:49 | 1 | |||
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C57BL/6N-Atm1Brd Trmt2atm2a(EUCOMM)Wtsi/Mmucd Resource Report Resource Website |
RRID:MMRRC_037040-UCD | Mus musculus | Research areas: ; Mutation Type: Targeted Mutation ; Collection: BaSH EUCOMM | |Trmt2a|| | 037040-UCD | Targeted Mutation | Mutant Mouse Resource and Research Center (MMRRC) | MMRRC | PMID:21677750 | MMRRC_37040-UCD, MMRRC_037040, MMRRC_374 | 2026-08-01 05:43:44 | 0 | ||||
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NOD.Cg-Pdcd1tm1.1Shr Ifngtm1Ts H2h4/HbmMmmh Resource Report Resource Website 1+ mentions Issue |
RRID:MMRRC_037145-MU | Mus musculus | Research areas: Immunology and Inflammation; Mutation Type: Targeted Mutation ; Collection: Mullen | increased leukocyte cell number [MP:0000218]| increased monocyte cell number [MP:0000220]| extramedullary hematopoiesis [MP:0000240]| increased granulocyte number [MP:0000322]| abnormal spleen morphology [MP:0000689]| enlarged spleen [MP:0000691]| abnormal lymph node size [MP:0000701]| enlarged lymph nodes [MP:0000702]| increased body weight [MP:0001260]| decreased body weight [MP:0001262]| increased metastatic potential [MP:0001272]| abnormal response to new environment [MP:0001413]| altered susceptibility to infection [MP:0001793]| abnormal humoral immune response [MP:0001800]| decreased IgG level [MP:0001805]| decreased IgM level [MP:0001806]| decreased IgA level [MP:0001807]| abnormal inflammatory response [MP:0001845]| increased inflammatory response [MP:0001846]| brain inflammation [MP:0001847]| kidney inflammation [MP:0001859]| liver inflammation [MP:0001860]| lung inflammation [MP:0001861]| stomach inflammation [MP:0001873]| decreased inflammatory response [MP:0001876]| abnormal lactation [MP:0001882]| mammary gland alveolar hyperplasia [MP:0001884]| decreased litter size [MP:0001935]| abnormal lung volume [MP:0001942]| increased airway responsiveness [MP:0001952]| emphysema [MP:0001958]| increased B cell derived lymphoma incidence [MP:0002023]| increased T cell derived lymphoma incidence [MP:0002024]| increased lung adenocarcinoma incidence [MP:0002027]| increased sarcoma incidence [MP:0002032]| increased carcinoma incidence [MP:0002038]| increased pituitary adenoma incidence [MP:0002041]| decreased tumor incidence [MP:0002052]| premature death [MP:0002083]| abnormal spleen size [MP:0002224]| abnormal pulmonary alveolus morphology [MP:0002270]| decreased airway responsiveness [MP:0002335]| abnormal lymph node cortex morphology [MP:0002343]| abnormal lymph node primary follicle morphology [MP:0002345]| abnormal lymph node secondary follicle morphology [MP:0002346]| abnormal spleen red pulp morphology [MP:0002356]| abnormal spleen white pulp morphology [MP:0002357]| abnormal dendritic cell physiology [MP:0002376]| increased susceptibility to bacterial infection [MP:0002412]| increased susceptibility to viral infection [MP:0002418]| abnormal adaptive immunity [MP:0002420]| altered susceptibility to autoimmune disorder [MP:0002425]| abnormal macrophage physiology [MP:0002451]| abnormal dendritic cell antigen presentation [MP:0002455]| abnormal B cell physiology [MP:0002459]| decreased immunoglobulin level [MP:0002460]| increased immunoglobulin level [MP:0002461]| abnormal immunoglobulin level [MP:0002490]| decreased IgE level [MP:0002492]| increased IgE level [MP:0002497]| abnormal type IV hypersensitivity reaction [MP:0002534]| glomerulonephritis [MP:0002743]| decreased vertical activity [MP:0002757]| albuminuria [MP:0002871]| increased circulating alanine transaminase level [MP:0002941]| abnormal cytokine secretion [MP:0003009]| abnormal redox activity [MP:0003186]| small intestinal inflammation [MP:0003306]| abnormal tumor morphology [MP:0003448]| increased fear-related response [MP:0003459]| abnormal pancreatic beta cell physiology [MP:0003562]| increased ovarian carcinoma incidence [MP:0003579]| increased autoantibody level [MP:0003725]| decreased autoantibody level [MP:0003726]| abnormal nitric oxide homeostasis [MP:0003957]| abnormal lung vasculature morphology [MP:0004007]| abnormal maternal decidual layer morphology [MP:0004256]| decreased length of allograft survival [MP:0004752]| decreased anti-nuclear antigen antibody level [MP:0004795]| decreased anti-double stranded DNA antibody level [MP:0004798]| increased susceptibility to experimental autoimmune encephalomyelitis [MP:0004799]| decreased susceptibility to systemic lupus erythematosus [MP:0004802]| decreased susceptibility to autoimmune diabetes [MP:0004804]| abnormal immune tolerance [MP:0005000]| increased eosinophil cell number [MP:0005011]| increased lymphocyte cell number [MP:0005013]| increased T cell number [MP:0005015]| abnormal response to infection [MP:0005025]| decreased susceptibility to parasitic infection [MP:0005026]| increased susceptibility to parasitic infection [MP:0005027]| abnormal MHC II cell surface expression on macrophages [MP:0005040]| impaired natural killer cell mediated cytotoxicity [MP:0005070]| abnormal cytotoxic T cell physiology [MP:0005078]| decreased double-negative T cell number [MP:0005089]| cachexia [MP:0005150]| abnormal response to injury [MP:0005164]| decreased susceptibility to injury [MP:0005166]| abnormal renal glomerulus morphology [MP:0005325]| atherosclerotic lesions [MP:0005338]| decreased susceptibility to autoimmune disorder [MP:0005351]| abnormal Langerhans cell physiology [MP:0005362]| increased susceptibility to fungal infection [MP:0005399]| abnormal skin physiology [MP:0005501]| corneal vascularization [MP:0005542]| decreased circulating creatinine level [MP:0005554]| increased blood urea nitrogen level [MP:0005565]| decreased susceptibility to type IV hypersensitivity reaction [MP:0005616]| increased susceptibility to type IV hypersensitivity reaction [MP:0005617]| abnormal response to transplant [MP:0005671]| abnormal mammary gland growth during pregnancy [MP:0006269]| increased NK T cell number [MP:0008039]| abnormal uterine NK cell morphology [MP:0008054]| increased CD4-positive [MP:0008074]| alpha beta T cell number [MP:0008078]| increased CD8-positive [MP:0008135]| alpha-beta T cell number [MP:0008466]| small Peyer's patches [MP:0008474]| enlarged mesenteric lymph nodes [MP:0008496]| absent spleen germinal center [MP:0008497]| decreased IgG2a level [MP:0008498]| decreased IgG2b level [MP:0008499]| decreased IgG3 level [MP:0008523]| increased IgG1 level [MP:0008567]| absent lymph node germinal center [MP:0008596]| decreased interferon-gamma secretion [MP:0008660]| increased circulating interleukin-6 level [MP:0008661]| increased interleukin-10 secretion [MP:0008663]| decreased interleukin-10 secretion [MP:0008681]| increased interleukin-12 secretion [MP:0008687]| increased interleukin-17 secretion [MP:0008699]| increased interleukin-2 secretion [MP:0008702]| increased interleukin-4 secretion [MP:0008713]| increased interleukin-5 secretion [MP:0008770]| abnormal cytokine level [MP:0008828]| decreased survivor rate [MP:0008874]| abnormal lymph node cell ratio [MP:0009099]| decreased physiological sensitivity to xenobiotic [MP:0009246]| abnormal uterine NK cell physiology [MP:0009336]| pale spleen [MP:0009394]| increased splenocyte proliferation [MP:0009419]| increased uterine NK cell number [MP:0009643]| skeletal muscle fibrosis [MP:0009763]| abnormal urine homeostasis [MP:0009766]| increased sensitivity to induced morbidity/mortality [MP:0009788]| increased sensitivity to xenobiotic induced morbidity/mortality [MP:0009791]| increased susceptibility to bacterial infection induced morbidity/mortality [MP:0009828]| increased susceptibility to viral infection induced morbidity/mortality [MP:0010210]| increased tumor latency [MP:0010308]| abnormal circulating cytokine level [MP:0010574]| decreased tumor latency [MP:0010639]| aorta dilation [MP:0010659]| altered tumor pathology [MP:0010740]| abdominal aorta aneurysm [MP:0010750]| abnormal dendritic cell chemotaxis [MP:0010751]| increased susceptibility to parasitic infection induced morbidity/mortality [MP:0010760]| decreased susceptibility to parasitic infection induced morbidity/mortality [MP:0010766]| abnormal macrophage chemotaxis [MP:0011086]| abnormal NK cell physiology [MP:0011320]| postnatal lethality [MP:0011427]| incomplete penetrance [MP:0012431]| abnormal glomerular capillary morphology [MP:0013239]| mesangial cell hyperplasia [MP:0013590]| increased lymphoma incidence [MP:0030466]| abnormal cytokine secretion [MP:0003009]| thyroid inflammation [MP:0003504]| insulitis [MP:0004031]| decreased susceptibility to autoimmune diabetes [MP:0004804]| periinsulitis [MP:0005580]| decreased physiological sensitivity to xenobiotic [MP:0008874]| vasculitis [MP:0001864]| pancreas inflammation [MP:0001869]| increased retinal ganglion cell number [MP:0002983]| insulitis [MP:0004031]| increased susceptibility to autoimmune diabetes [MP:0004803]| increased regulatory T cell number [MP:0004973]| decreased B-1 B cell number [MP:0004978]| abnormal immune tolerance [MP:0005000]| decreased T cell proliferation [MP:0005095]| increased T cell proliferation [MP:0005348] | |Pdcd1||Ifng|| | 037145-MU | Targeted Mutation | Mutant Mouse Resource and Research Center (MMRRC) | MMRRC | MMRRC_37145-MU, MMRRC_037145, MMRRC_37145 | 2026-08-01 05:43:46 | 1 | ||||
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B6.C-Tg(Grk1)1ShakMmmh Resource Report Resource Website |
RRID:MMRRC_037057-MU | Mus musculus | Research areas: Neurobiology, Research Tools; Mutation Type: Transgenic ; Collection: | Grk1 | 037057-MU | Transgenic | Mutant Mouse Resource and Research Center (MMRRC) | MMRRC | MMRRC_37057-MU, MMRRC_037057, MMRRC_3757 | 2026-08-01 05:43:44 | 0 | |||||
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B6.129S1-Artm3(AR)Dmr/Mmnc Resource Report Resource Website |
RRID:MMRRC_037118-UNC | Mus musculus | Research areas: Cancer, Endocrine Deficiency, Models for Human Disease, Neurobiology, Reproduction, Research Tools; Mutation Type: Targeted Mutation ; Collection: | increased body weight [MP:0001260]| decreased tumor incidence [MP:0002052]| increased percent body fat/body weight [MP:0005458] | Ar|AR| | 037118-UNC | Targeted Mutation | Mutant Mouse Resource and Research Center (MMRRC) | MMRRC | PMID:16601069 | MMRRC_37118-UNC, MMRRC_037118, MMRRC_37118 | 2026-08-01 05:43:49 | 0 | |||
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C57BL/6J-Rag2m1Btlr/Mmmh Resource Report Resource Website |
RRID:MMRRC_037091-MU | Mus musculus | Research areas: Cell Biology, Immunology and Inflammation, Models for Human Disease, Virology; Mutation Type: chemically induced mutation ; Collection: Beutler Mutagenetix | abnormal humoral immune response [MP:0001800]| decreased IgG level [MP:0001805]| decreased IgM level [MP:0001806]| decreased B cell number [MP:0005017]| decreased CD4-positive [MP:0008075] | Rag2 | 037091-MU | chemically induced mutation | Mutant Mouse Resource and Research Center (MMRRC) | MMRRC | MMRRC_37091-MU, MMRRC_037091, MMRRC_3791 | 2026-08-01 05:43:45 | 0 | ||||
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C57BL/6N-Atm1Brd Pld3tm1e(EUCOMM)Wtsi/Mmucd Resource Report Resource Website |
RRID:MMRRC_037027-UCD | Mus musculus | Research areas: ; Mutation Type: ; Collection: Sanger EUCOMM Collection | decreased mean corpuscular volume [MP:0002591]| thrombocytopenia [MP:0003179]| decreased circulating glucose level [MP:0005560]| decreased mean corpuscular hemoglobin [MP:0005562]| decreased NK T cell number [MP:0008040]| decreased mature B cell number [MP:0008211]| increased gamma-delta T cell number [MP:0008346]| increased red blood cell distribution width [MP:0010067] | Pld3 | 037027-UCD | Mutant Mouse Resource and Research Center (MMRRC) | MMRRC | PMID:21677750 | MMRRC_37027-UCD, MMRRC_037027, MMRRC_3727 | 2026-08-01 05:43:44 | 0 | ||||
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C57BL/6N-Zkscan17tm1a(EUCOMM)Wtsi/Mmucd Resource Report Resource Website |
RRID:MMRRC_037045-UCD | Mus musculus | Research areas: ; Mutation Type: Targeted Mutation ; Collection: BaSH EUCOMM | |Zkscan17| | 037045-UCD | Targeted Mutation | Mutant Mouse Resource and Research Center (MMRRC) | MMRRC | PMID:21677750 | MMRRC_37045-UCD, MMRRC_037045, MMRRC_3745 | 2026-08-01 05:44:02 | 0 | ||||
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STOCK Tg(hs192-cre/ERT2,-GFP)1040Jlr/Mmucd Resource Report Resource Website |
RRID:MMRRC_037134-UCD | Mus musculus | Research areas: Developmental Biology, Neurobiology; Mutation Type: Transgenic ; Collection: Human Element Enhancers | |SOX2-OT|DNAJC19|cre/ERT2|GFP | 037134-UCD | Transgenic | Mutant Mouse Resource and Research Center (MMRRC) | MMRRC | PMID:24814534 | MMRRC_37134-UCD, MMRRC_037134, MMRRC_37134 | 2026-08-01 05:43:46 | 0 | ||||
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C57BL/6N-Tatdn3tm1a(EUCOMM)Wtsi Atm1Brd/Mmucd Resource Report Resource Website |
RRID:MMRRC_037037-UCD | Mus musculus | Research areas: ; Mutation Type: Targeted Mutation ; Collection: BaSH EUCOMM | decreased blood urea nitrogen level [MP:0005566] | |Tatdn3|| | 037037-UCD | Targeted Mutation | Mutant Mouse Resource and Research Center (MMRRC) | MMRRC | PMID:21677750 PMID:27626380 |
MMRRC_37037-UCD, MMRRC_037037, MMRRC_3737 | 2026-08-01 05:43:44 | 0 | |||
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B6.129P2(Cg)-Izumo1rtm1.1Salb/Mmnc Resource Report Resource Website 1+ mentions |
RRID:MMRRC_037093-UNC | Mus musculus | Research areas: Cell Biology, Developmental Biology, Immunology and Inflammation, Reproduction; Mutation Type: Targeted Mutation ; Collection: | female infertility [MP:0001926] | Izumo1r | 037093-UNC | Targeted Mutation | Mutant Mouse Resource and Research Center (MMRRC) | MMRRC | PMID:23651732 | MMRRC_37093-UNC, MMRRC_037093, MMRRC_3793 | 2026-08-01 05:43:45 | 2 | |||
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B6.Cg-Eri1tm1.1Anse/Mmucd Resource Report Resource Website |
RRID:MMRRC_037122-UCD | Mus musculus | Research areas: Cell Biology, Dermatology, Developmental Biology, Hematology, Immunology and Inflammation, Metabolism, Models for Human Disease, Neurobiology, Reproduction, Sensorineural, Virology; Mutation Type: other ; Collection: | Eri1 | 037122-UCD | other | Mutant Mouse Resource and Research Center (MMRRC) | MMRRC | PMID:18438418 | MMRRC_37122-UCD, MMRRC_037122, MMRRC_37122 | 2026-08-01 05:43:45 | 0 | ||||
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C57BL/6N-Atm1Brd Trim29tm1a(EUCOMM)Wtsi/Mmucd Resource Report Resource Website |
RRID:MMRRC_037039-UCD | Mus musculus | Research areas: ; Mutation Type: Targeted Mutation ; Collection: BaSH EUCOMM | |Trim29|| | 037039-UCD | Targeted Mutation | Mutant Mouse Resource and Research Center (MMRRC) | MMRRC | PMID:21677750 PMID:27626380 |
MMRRC_37039-UCD, MMRRC_037039, MMRRC_3739 | 2026-08-01 05:44:02 | 0 | ||||
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STOCK Sox2tm4Lpev/Mmnc Resource Report Resource Website |
RRID:MMRRC_037151-UNC | Mus musculus | Research areas: Developmental Biology, Models for Human Disease, Neurobiology, Sensorineural; Mutation Type: Targeted Mutation ; Collection: | anophthalmia [MP:0001293]| microphthalmia [MP:0001297]| disorganized retinal layers [MP:0001328]| retina hyperplasia [MP:0001329]| no abnormal phenotype detected [MP:0002169]| optic nerve hypoplasia [MP:0006221] | Sox2 | 037151-UNC | Targeted Mutation | Mutant Mouse Resource and Research Center (MMRRC) | MMRRC | PMID:16651659 PMID:22522080 PMID:23638914 |
MMRRC_37151-UNC, MMRRC_037151, MMRRC_37151 | 2026-08-01 05:43:50 | 0 | |||
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B6.129S1-Artm2(AR)Dmr/Mmnc Resource Report Resource Website |
RRID:MMRRC_037108-UNC | Mus musculus | Research areas: Cancer, Endocrine Deficiency, Models for Human Disease, Neurobiology, Reproduction, Research Tools; Mutation Type: Targeted Mutation ; Collection: | increased prostate gland tumor incidence [MP:0010357] | Ar|AR| | 037108-UNC | Targeted Mutation | Mutant Mouse Resource and Research Center (MMRRC) | MMRRC | PMID:16601069 | MMRRC_37108-UNC, MMRRC_037108, MMRRC_3718 | 2026-08-01 05:44:02 | 0 | |||
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NOD.Cg-Ifngtm1Ts Ighmtm1Cgn H2h4/HbmMmmh Resource Report Resource Website Issue Issue Issue |
RRID:MMRRC_037144-MU | Mus musculus | Research areas: Immunology and Inflammation; Mutation Type: Targeted Mutation ; Collection: Mullen | abnormal cytokine secretion [MP:0003009]| thyroid inflammation [MP:0003504]| insulitis [MP:0004031]| decreased susceptibility to autoimmune diabetes [MP:0004804]| periinsulitis [MP:0005580]| decreased physiological sensitivity to xenobiotic [MP:0008874]| decreased bone mineral density [MP:0000063]| abnormal trabecular bone morphology [MP:0000130]| decreased compact bone thickness [MP:0000135]| enlarged heart [MP:0000274]| increased cell proliferation [MP:0000351]| abnormal intestinal epithelium morphology [MP:0000488]| abnormal spleen morphology [MP:0000689]| enlarged lymph nodes [MP:0000702]| abnormal skin condition [MP:0001191]| abnormal cardiovascular system physiology [MP:0001544]| abnormal humoral immune response [MP:0001800]| arrested B cell differentiation [MP:0001802]| decreased IgG level [MP:0001805]| decreased IgM level [MP:0001806]| decreased IgA level [MP:0001807]| thymus hypoplasia [MP:0001823]| abnormal antigen presentation [MP:0001835]| abnormal inflammatory response [MP:0001845]| increased inflammatory response [MP:0001846]| heart inflammation [MP:0001853]| myocarditis [MP:0001856]| kidney inflammation [MP:0001859]| abnormal lymphatic vessel morphology [MP:0001879]| premature death [MP:0002083]| abnormal respiratory system physiology [MP:0002133]| abnormal B cell differentiation [MP:0002144]| abnormal spleen marginal sinus morphology [MP:0002363]| abnormal B lymphocyte antigen presentation [MP:0002453]| decreased immunoglobulin level [MP:0002460]| abnormal immunoglobulin level [MP:0002490]| decreased IgE level [MP:0002492]| tubular nephritis [MP:0002704]| increased urine protein level [MP:0002962]| abnormal cytokine secretion [MP:0003009]| cardiac fibrosis [MP:0003141]| thrombocytopenia [MP:0003179]| small intestinal inflammation [MP:0003306]| increased susceptibility to induced arthritis [MP:0003724]| increased autoantibody level [MP:0003725]| abnormal compact bone morphology [MP:0003797]| abnormal PR interval [MP:0003901]| insulitis [MP:0004031]| decreased susceptibility to systemic lupus erythematosus [MP:0004802]| increased susceptibility to autoimmune diabetes [MP:0004803]| decreased susceptibility to autoimmune diabetes [MP:0004804]| decreased spleen weight [MP:0004953]| increased osteoclast cell number [MP:0004984]| increased T cell number [MP:0005015]| decreased B cell number [MP:0005017]| abnormal response to infection [MP:0005025]| increased susceptibility to parasitic infection [MP:0005027]| abnormal T cell proliferation [MP:0005094]| decreased T cell proliferation [MP:0005095]| cachexia [MP:0005150]| decreased susceptibility to injury [MP:0005166]| abnormal pancreatic islet morphology [MP:0005215]| abnormal CD4-positive [MP:0005463]| alpha-beta T cell physiology [MP:0005559]| increased circulating glucose level [MP:0005616]| decreased susceptibility to type IV hypersensitivity reaction [MP:0006387]| abnormal T cell number [MP:0008071]| absent B cells [MP:0008075]| decreased CD4-positive [MP:0008079]| alpha beta T cell number [MP:0008127]| decreased CD8-positive [MP:0008171]| alpha-beta T cell number [MP:0008201]| decreased dendritic cell number [MP:0008211]| abnormal mature B cell morphology [MP:0008212]| absent follicular dendritic cells [MP:0008213]| decreased mature B cell number [MP:0008240]| absent mature B cells [MP:0008241]| absent immature B cells [MP:0008401]| abnormal spleen marginal zone macrophage morphology [MP:0008470]| abnormal metallophilic macrophage morphology [MP:0008495]| abnormal CD8 positive [MP:0009346]| alpha-beta intraepithelial T cell morphology [MP:0010965]| abnormal spleen B cell follicle morphology [MP:0012431]| increased leukocyte cell number [MP:0000218]| increased monocyte cell number [MP:0000220]| extramedullary hematopoiesis [MP:0000240]| increased granulocyte number [MP:0000322]| abnormal spleen morphology [MP:0000689]| enlarged spleen [MP:0000691]| abnormal lymph node size [MP:0000701]| enlarged lymph nodes [MP:0000702]| increased body weight [MP:0001260]| decreased body weight [MP:0001262]| increased metastatic potential [MP:0001272]| abnormal response to new environment [MP:0001413]| altered susceptibility to infection [MP:0001793]| abnormal humoral immune response [MP:0001800]| decreased IgG level [MP:0001805]| decreased IgM level [MP:0001806]| decreased IgA level [MP:0001807]| abnormal inflammatory response [MP:0001845]| increased inflammatory response [MP:0001846]| brain inflammation [MP:0001847]| kidney inflammation [MP:0001859]| liver inflammation [MP:0001860]| lung inflammation [MP:0001861]| stomach inflammation [MP:0001873]| decreased inflammatory response [MP:0001876]| abnormal lactation [MP:0001882]| mammary gland alveolar hyperplasia [MP:0001884]| decreased litter size [MP:0001935]| abnormal lung volume [MP:0001942]| increased airway responsiveness [MP:0001952]| emphysema [MP:0001958]| increased B cell derived lymphoma incidence [MP:0002023]| increased T cell derived lymphoma incidence [MP:0002024]| increased lung adenocarcinoma incidence [MP:0002027]| increased sarcoma incidence [MP:0002032]| increased carcinoma incidence [MP:0002038]| increased pituitary adenoma incidence [MP:0002041]| decreased tumor incidence [MP:0002052]| premature death [MP:0002083]| abnormal spleen size [MP:0002224]| abnormal pulmonary alveolus morphology [MP:0002270]| decreased airway responsiveness [MP:0002335]| abnormal lymph node cortex morphology [MP:0002343]| abnormal lymph node primary follicle morphology [MP:0002345]| abnormal lymph node secondary follicle morphology [MP:0002346]| abnormal spleen red pulp morphology [MP:0002356]| abnormal spleen white pulp morphology [MP:0002357]| abnormal dendritic cell physiology [MP:0002376]| increased susceptibility to bacterial infection [MP:0002412]| increased susceptibility to viral infection [MP:0002418]| abnormal adaptive immunity [MP:0002420]| altered susceptibility to autoimmune disorder [MP:0002425]| abnormal macrophage physiology [MP:0002451]| abnormal dendritic cell antigen presentation [MP:0002455]| abnormal B cell physiology [MP:0002459]| decreased immunoglobulin level [MP:0002460]| increased immunoglobulin level [MP:0002461]| abnormal immunoglobulin level [MP:0002490]| decreased IgE level [MP:0002492]| increased IgE level [MP:0002497]| abnormal type IV hypersensitivity reaction [MP:0002534]| glomerulonephritis [MP:0002743]| decreased vertical activity [MP:0002757]| albuminuria [MP:0002871]| increased circulating alanine transaminase level [MP:0002941]| abnormal cytokine secretion [MP:0003009]| abnormal redox activity [MP:0003186]| small intestinal inflammation [MP:0003306]| abnormal tumor morphology [MP:0003448]| increased fear-related response [MP:0003459]| abnormal pancreatic beta cell physiology [MP:0003562]| increased ovarian carcinoma incidence [MP:0003579]| increased autoantibody level [MP:0003725]| decreased autoantibody level [MP:0003726]| abnormal nitric oxide homeostasis [MP:0003957]| abnormal lung vasculature morphology [MP:0004007]| abnormal maternal decidual layer morphology [MP:0004256]| decreased length of allograft survival [MP:0004752]| decreased anti-nuclear antigen antibody level [MP:0004795]| decreased anti-double stranded DNA antibody level [MP:0004798]| increased susceptibility to experimental autoimmune encephalomyelitis [MP:0004799]| decreased susceptibility to systemic lupus erythematosus [MP:0004802]| decreased susceptibility to autoimmune diabetes [MP:0004804]| abnormal immune tolerance [MP:0005000]| increased eosinophil cell number [MP:0005011]| increased lymphocyte cell number [MP:0005013]| increased T cell number [MP:0005015]| abnormal response to infection [MP:0005025]| decreased susceptibility to parasitic infection [MP:0005026]| increased susceptibility to parasitic infection [MP:0005027]| abnormal MHC II cell surface expression on macrophages [MP:0005040]| impaired natural killer cell mediated cytotoxicity [MP:0005070]| abnormal cytotoxic T cell physiology [MP:0005078]| decreased double-negative T cell number [MP:0005089]| cachexia [MP:0005150]| abnormal response to injury [MP:0005164]| decreased susceptibility to injury [MP:0005166]| abnormal renal glomerulus morphology [MP:0005325]| atherosclerotic lesions [MP:0005338]| decreased susceptibility to autoimmune disorder [MP:0005351]| abnormal Langerhans cell physiology [MP:0005362]| increased susceptibility to fungal infection [MP:0005399]| abnormal skin physiology [MP:0005501]| corneal vascularization [MP:0005542]| decreased circulating creatinine level [MP:0005554]| increased blood urea nitrogen level [MP:0005565]| decreased susceptibility to type IV hypersensitivity reaction [MP:0005616]| increased susceptibility to type IV hypersensitivity reaction [MP:0005617]| abnormal response to transplant [MP:0005671]| abnormal mammary gland growth during pregnancy [MP:0006269]| increased NK T cell number [MP:0008039]| abnormal uterine NK cell morphology [MP:0008054]| increased CD4-positive [MP:0008074]| alpha beta T cell number [MP:0008078]| increased CD8-positive [MP:0008135]| alpha-beta T cell number [MP:0008466]| small Peyer's patches [MP:0008474]| enlarged mesenteric lymph nodes [MP:0008496]| absent spleen germinal center [MP:0008497]| decreased IgG2a level [MP:0008498]| decreased IgG2b level [MP:0008499]| decreased IgG3 level [MP:0008523]| increased IgG1 level [MP:0008567]| absent lymph node germinal center [MP:0008596]| decreased interferon-gamma secretion [MP:0008660]| increased circulating interleukin-6 level [MP:0008661]| increased interleukin-10 secretion [MP:0008663]| decreased interleukin-10 secretion [MP:0008681]| increased interleukin-12 secretion [MP:0008687]| increased interleukin-17 secretion [MP:0008699]| increased interleukin-2 secretion [MP:0008702]| increased interleukin-4 secretion [MP:0008713]| increased interleukin-5 secretion [MP:0008770]| abnormal cytokine level [MP:0008828]| decreased survivor rate [MP:0008874]| abnormal lymph node cell ratio [MP:0009099]| decreased physiological sensitivity to xenobiotic [MP:0009246]| abnormal uterine NK cell physiology [MP:0009336]| pale spleen [MP:0009394]| increased splenocyte proliferation [MP:0009419]| increased uterine NK cell number [MP:0009643]| skeletal muscle fibrosis [MP:0009763]| abnormal urine homeostasis [MP:0009766]| increased sensitivity to induced morbidity/mortality [MP:0009788]| increased sensitivity to xenobiotic induced morbidity/mortality [MP:0009791]| increased susceptibility to bacterial infection induced morbidity/mortality [MP:0009828]| increased susceptibility to viral infection induced morbidity/mortality [MP:0010210]| increased tumor latency [MP:0010308]| abnormal circulating cytokine level [MP:0010574]| decreased tumor latency [MP:0010639]| aorta dilation [MP:0010659]| altered tumor pathology [MP:0010740]| abdominal aorta aneurysm [MP:0010750]| abnormal dendritic cell chemotaxis [MP:0010751]| increased susceptibility to parasitic infection induced morbidity/mortality [MP:0010760]| decreased susceptibility to parasitic infection induced morbidity/mortality [MP:0010766]| abnormal macrophage chemotaxis [MP:0011086]| abnormal NK cell physiology [MP:0011320]| postnatal lethality [MP:0011427]| incomplete penetrance [MP:0012431]| abnormal glomerular capillary morphology [MP:0013239]| mesangial cell hyperplasia [MP:0013590]| increased lymphoma incidence [MP:0030466] | Ighm||Ifng||| | 037144-MU | Targeted Mutation | Mutant Mouse Resource and Research Center (MMRRC) | MMRRC | PMID:23509363 | MMRRC_37144-MU, MMRRC_037144, MMRRC_37144 | 2026-08-01 05:43:46 | 0 |
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