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Integrated Animals is a virtual database currently indexing available animal strains and mutants from: AGSC (Ambystoma), BCBC (mice), BDSC (flies), European Xenopus Resource Center (frog), The National Xenopus Resource (frog), Xenopus Express (frog), CWRU Cystic Fibrosis Mouse Models (mice), DGGR (flies), FlyBase (flies), IMSR (mice), MGI (mice), MMRRC (mice), NSRRC (pig), RGD (rats), Sperm Stem Cell Libraries for Biological Research (rats), Tetrahymena Stock Center (Tetrahymena), WormBase (worms), XGSC (Xiphophorus), ZFIN (zebrafish), and ZIRC (zebrafish). Note, the IMSR data is linked, but users may need to re-execute the search if the top mouse is not returned properly.
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Organism Name Proper Citation Species Synonyms Notes Phenotype Affected Gene Genomic Alteration Catalog Number Background Database Database Abbreviation Availability Source References Alternate IDs Authority Record Last Update Mentions Count
kstSi61 II; unc-119(ed3) III.
 
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RRID:WB-STRAIN:WBStrain00051611 Caenorhabditis elegans kstSi61 II; unc-119(ed3) III. kstSi61 [LoxP + Cbr-unc-119(+) + LoxP + hygroR(kst31)] II. N2-like, no hygromycin resistance (HygroR). hygroR(kst31) is a partial, non-functional hygromycin-resistance construct used for section in MosTI, an updated technique for targeted single-copy and extra-chromosomal array insertion. Cbr-unc-119(+) is flanked by LoxP sites, facilitating removal by recombination. Reference: El Mouridi S, et al. 2022. WBGene00006843(unc-119) WBGene00006843(unc-119) WB-STRAIN:WBStrain00051611 WormBase (WB) WB unknown WormBase 2026-10-10 11:02:32 0
kstSi32 I; unc-119(ed3) III.
 
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RRID:WB-STRAIN:WBStrain00051608 Caenorhabditis elegans kstSi32 I; unc-119(ed3) III. kstSi32 [Cbr-unc-119(kst13)] I. Unc. Cbr-unc-119(kst13) is a partial unc-119 used for section in MosTI, an updated technique for targeted single-copy and extra-chromosomal array insertion. Reference: El Mouridi S, et al. 2022. WBGene00006843(unc-119) WBGene00006843(unc-119) WB-STRAIN:WBStrain00051608 WormBase (WB) WB unknown WormBase 2026-10-10 11:02:32 0
unc-119(ox819 oxTi1126) III.
 
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RRID:WB-STRAIN:WBStrain00051652 Caenorhabditis elegans unc-119(ox819 oxTi1126) III. oxTi1126 [mex-5p::Cas9(+smu-2 introns)::tbb-2 3'UTR + hsp-16.41p::Cre::tbb-2 3'UTR + myo-2p::2xNLS::cyOFP::let-858 3'UTR + lox2272] III. Knock-in into previously modified unc-119(ox819) endogenous locus. Cas9 insertion marked with myo-2p::cyOFP (cyan-excitable Orange Fluorescent Protein), a long-Stokes-shift fluorescent protein that is spectrally separable from common green and red fluorophores. The Cas9 transgene was optimized for germline expression by including 4 large PATC-rich introns from smu-2. Lower activity than other Cas9 strains, but useful because Cas9, Cre, and unc-119 are in a single unit. Reference: Schwartz ML, et al. High-efficiency CRISPR gene editing in C. elegans using Cas9 integrated into the genome. bioRxiv 2021.08.03.454883; doi: https: WBGene00006843(unc-119) WBGene00006843(unc-119) WB-STRAIN:WBStrain00051652 WormBase (WB) WB unknown WormBase 2026-10-10 11:02:33 1
unc-119(ox819) III; W03F9.11(oxTi1121) V.
 
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RRID:WB-STRAIN:WBStrain00051658 Caenorhabditis elegans unc-119(ox819) III; W03F9.11(oxTi1121) V. oxTi1121 [mex-5p::Cas9(+smu-2 introns)::tbb-2 3'UTR + hsp-16.41p::Cre::tbb-2 3'UTR + lox2272]) V. The Cas9 transgene was optimized for germline expression by including 4 large PATC-rich introns from smu-2. Inserted into W03F9.11. Reference: Schwartz ML, et al. High-efficiency CRISPR gene editing in C. elegans using Cas9 integrated into the genome. bioRxiv 2021.08.03.454883; doi: https: WBGene00006843(unc-119) WBGene00006843(unc-119) WB-STRAIN:WBStrain00051658 WormBase (WB) WB unknown WormBase 2026-10-10 11:02:33 0
W01A8.6(oxTi1128) I; unc-119(ox819) III.
 
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RRID:WB-STRAIN:WBStrain00051656 Caenorhabditis elegans W01A8.6(oxTi1128) I; unc-119(ox819) III. oxTi1128 [mex-5p::Cas9(+smu-2 introns)::tbb-2 3'UTR + hsp-16.41p::Cre::tbb-2 3'UTR + myo-2p::2xNLS::cyOFP::let-858 3'UTR + lox2272]) I. Cas9 insertion marked with myo-2p::cyOFP (cyan-excitable Orange Fluorescent Protein), a long-Stokes-shift fluorescent protein that is spectrally separable from common green and red fluorophores. Inserted into W01A8.6. Reference: Schwartz ML, et al. High-efficiency CRISPR gene editing in C. elegans using Cas9 integrated into the genome. bioRxiv 2021.08.03.454883; doi: https: WBGene00006843(unc-119) WBGene00006843(unc-119) WB-STRAIN:WBStrain00051656 WormBase (WB) WB unknown WormBase 2026-10-10 11:02:33 0
muIs252 II; unc-119(ed3) his-72(utx21[his-72::wrmScarlet11::3xMyc]) III.
 
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RRID:WB-STRAIN:WBStrain00051686 Caenorhabditis elegans muIs252 II; unc-119(ed3) his-72(utx21[his-72::wrmScarlet11::3xMyc]) III. Made_by: Ella DeMott (Glow Worms '20)|"muIs252 [eft-3p::wrmScarlet1-10::unc-54 3'UTR + Cbr-unc-119(+)] II. C-terminal tag of HIS-72 via CRISPR/Cas9 knock-in of wrmScarlet11 into endogenous his-72 locus. Genetic background: strain CF4582. Insertion verified by PCR and fluorescence. Left flank: 5' CTCGCCAGACGCATTCGCGGAGAACGTGCT 3' (one silent mutation); Right flank: 5' TAAgctccatcaccaattctcgaagcactt 3'; sgRNA: GAGCTTAAGCACGTTCTCCG; Cas9/sgRNA plasmid: pGLOW87; wrmScarlet11^SEC^3xMyc plasmid: pGLOW88; SEC insertion allele strain: GLW26" WBGene00001946(his-72)|WBGene00006843(unc-119) WBGene00001946(his-72), WBGene00006843(unc-119) WB-STRAIN:WBStrain00051686 WormBase (WB) WB unknown WormBase 2026-10-10 11:02:33 0
oxIs322 II; unc-119(ed3) III; lucEx1311.
 
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RRID:WB-STRAIN:WBStrain00051772 Caenorhabditis elegans oxIs322 II; unc-119(ed3) III; lucEx1311. Made_by: Paula Gutirrez-Prez|"oxIs322 [myo-2p::mCherry::H2B + myo-3p::mCherry::H2B + Cbr-unc-119(+)]. lucEx1311 (myo-3p::R2pH::LAMP1::3xFLAG::unc-54 3UTR + ttx-3p::mCherry). Pick mCherry+ to maintain. Reference: Gutierrez-Perez, P. et al. A deeply conserved miR-1 dependent regulon supports muscle cell physiology. bioRxiv, 2020, doi.org/10.1101/2020.08.31.275644." WBGene00006843(unc-119) WBGene00006843(unc-119) WB-STRAIN:WBStrain00051772 WormBase (WB) WB unknown WormBase 2026-10-10 11:02:35 0
daf-2(hq363[daf-2::degron::mNeonGreen]) unc-119(ed3) III; ieSi38 IV.
 
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RRID:WB-STRAIN:WBStrain00051779 Caenorhabditis elegans daf-2(hq363[daf-2::degron::mNeonGreen]) unc-119(ed3) III; ieSi38 IV. ieSi38 [sun-1p::TIR1::mRuby::sun-1 3' UTR + Cbr-unc-119(+)] IV. Degron and mNeonGreen tag inserted at the 3' end of the endogenous daf-2 gene locus by CRISPR/Cas9 engineering. A single copy transgene was inserted into chromosome IV (cxTi10882) expressing modified Arabidopsis thaliana TIR1 tagged with mRuby in germ line and early embryos. This strain can be used for auxin-inducible degradation (AID) of DAF-2 protein in the germ line.|"Made_by: Yan-Ping Zhang, Wen-Hong Zhang" WBGene00000898(daf-2)|WBGene00006843(unc-119) WBGene00000898(daf-2), WBGene00006843(unc-119) WB-STRAIN:WBStrain00051779 WormBase (WB) WB unknown WormBase 2026-10-10 11:02:35 0
ieSi61 II; daf-2(hq363[daf-2::degron::mNeonGreen]) unc-119(ed3) III.
 
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RRID:WB-STRAIN:WBStrain00051778 Caenorhabditis elegans ieSi61 II; daf-2(hq363[daf-2::degron::mNeonGreen]) unc-119(ed3) III. ieSi61 [ges-1p::TIR1::mRuby::unc-54 3' UTR + Cbr-unc-119(+)] II. Degron and mNeonGreen tag inserted at the 3' end of the endogenous daf-2 gene locus by CRISPR/Cas9 engineering. A single copy transgene was inserted into chromosome II (oxTi179) expressing modified Arabidopsis thaliana TIR1 tagged with mRuby in the intestine. This strain can be used for auxin-inducible degradation (AID) of DAF-2 protein in the intestine. Reference: Zhang Y, et al. BioRxiv. 2021 Aug 2. 2007.2031.454567. https:|"Made_by: Yan-Ping Zhang, Wen-Hong Zhang" WBGene00000898(daf-2)|WBGene00006843(unc-119) WBGene00000898(daf-2), WBGene00006843(unc-119) WB-STRAIN:WBStrain00051778 WormBase (WB) WB unknown WormBase 2026-10-10 11:02:35 0
hqSi8 II; daf-2(hq363[daf-2::degron::mNeonGreen]) unc-119(ed3) III.
 
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RRID:WB-STRAIN:WBStrain00051777 Caenorhabditis elegans hqSi8 II; daf-2(hq363[daf-2::degron::mNeonGreen]) unc-119(ed3) III. hqSi8 [rgef-1p::TIR1::mRuby::unc-54 3UTR+Cbr-unc-119(+)] II. Degron and mNeonGreen tag inserted at the 3' end of the endogenous daf-2 gene locus by CRISPR/Cas9 engineering. hqSi8 was generated by replacing the eft-3 promoter of the ieSi57 insertion (oxTi179 site) with the rgef-1 promoter using CRISPR/Cas9. This strain can be used for auxin-inducible degradation (AID) of DAF-2 protein in the neurons. hqSi8 previously known as hq373. Reference: Zhang Y, et al. BioRxiv. 2021 Aug 2. 2007.2031.454567. https:|"Made_by: Yan-Ping Zhang, Wen-Hong Zhang" WBGene00000898(daf-2)|WBGene00006843(unc-119) WBGene00000898(daf-2), WBGene00006843(unc-119) WB-STRAIN:WBStrain00051777 WormBase (WB) WB unknown WormBase 2026-10-10 11:02:35 0
daf-16(hq389[daf-16::gfp::degron]) I; daf-2(e1370) unc-119(ed3) III; ieSi38 IV.
 
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RRID:WB-STRAIN:WBStrain00051793 Caenorhabditis elegans daf-16(hq389[daf-16::gfp::degron]) I; daf-2(e1370) unc-119(ed3) III; ieSi38 IV. ieSi38 [sun-1p::TIR1::mRuby::sun-1 3' UTR + Cbr-unc-119(+)] IV. Maintain at 15C. GFP tag and degron inserted at the 3' end of the endogenous daf-16 gene locus by CRISPR/Cas9 engineering.This strain can be used for auxin-inducible degradation (AID) of DAF-16 protein in the germ line. Reference: Zhang Y, et al. BioRxiv. 2021 Aug 2. 2007.2031.454567. https:|"Made_by: Yan-Ping Zhang, Wen-Hong Zhang" WBGene00000898(daf-2)|WBGene00000912(daf-16)|WBGene00006843(unc-119) WBGene00000898(daf-2), WBGene00000912(daf-16), WBGene00006843(unc-119) WB-STRAIN:WBStrain00051793 WormBase (WB) WB unknown WormBase 2026-10-10 11:02:35 0
daf-16(hq389[daf-16::gfp::degron]) I; hqSi11 II; daf-2(e1370) unc-119(ed3) III.
 
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RRID:WB-STRAIN:WBStrain00051795 Caenorhabditis elegans daf-16(hq389[daf-16::gfp::degron]) I; hqSi11 II; daf-2(e1370) unc-119(ed3) III. hqSi11 [lim-7p::TIR1::mRuby::unc-54 3' UTR + Cbr-unc-119(+)] II. Maintain at 15C. GFP tag and degron inserted at the 3' end of the endogenous daf-16 gene locus by CRISPR/Cas9 engineering. hqSi11 was generated by replacing the eft-3 promoter of the ieSi57 insertion (oxTi179 site) with the lim-7 promoter using CRISPR/Cas9. This strain can be used for auxin-inducible degradation (AID) of DAF-16 protein in the gonadal sheath. hqSi11 previously known as hq378. Reference: Zhang Y, et al. BioRxiv. 2021 Aug 2. 2007.2031.454567. https:|"Made_by: Yan-Ping Zhang, Wen-Hong Zhang" WBGene00000898(daf-2)|WBGene00000912(daf-16)|WBGene00006843(unc-119) WBGene00000898(daf-2), WBGene00000912(daf-16), WBGene00006843(unc-119) WB-STRAIN:WBStrain00051795 WormBase (WB) WB unknown WormBase 2026-10-10 11:02:35 0
hqSi11 II; daf-2(hq363[daf-2::degron::mNeonGreen]) unc-119(ed3) III.
 
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RRID:WB-STRAIN:WBStrain00051782 Caenorhabditis elegans hqSi11 II; daf-2(hq363[daf-2::degron::mNeonGreen]) unc-119(ed3) III. hqSi11 [lim-7p::TIR1::mRuby::unc-54 3' UTR + Cbr-unc-119(+)] II. Degron and mNeonGreen tag inserted at the 3' end of the endogenous daf-2 gene locus by CRISPR/Cas9 engineering. hqSi11 was generated by replacing the eft-3 promoter of the ieSi57 insertion (oxTi179 site) with the lim-7 promoter using CRISPR/Cas9. This strain can be used for auxin-inducible degradation (AID) of DAF-2 protein in the gonadal sheath. hqSi11 previously known as hq378. Reference: Zhang Y, et al. BioRxiv. 2021 Aug 2. 2007.2031.454567. https:|"Made_by: Yan-Ping Zhang, Wen-Hong Zhang" WBGene00000898(daf-2)|WBGene00006843(unc-119) WBGene00000898(daf-2), WBGene00006843(unc-119) WB-STRAIN:WBStrain00051782 WormBase (WB) WB unknown WormBase 2026-10-10 11:02:35 0
hqSi10 II; daf-2(hq363[daf-2::degron::mNeonGreen]) unc-119(ed3) III.
 
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RRID:WB-STRAIN:WBStrain00051781 Caenorhabditis elegans hqSi10 II; daf-2(hq363[daf-2::degron::mNeonGreen]) unc-119(ed3) III. hqSi10 [myo-3p::TIR1::mRuby::unc-54 3' UTR + Cbr-unc-119(+)] II. Degron and mNeonGreen tag inserted at the 3' end of the endogenous daf-2 gene locus by CRISPR/Cas9 engineering. hqSi10 was generated by replacing the eft-3 promoter of the ieSi57 insertion (oxTi179 site) with the myo-3 promoter using CRISPR/Cas9. This strain can be used for auxin-inducible degradation (AID) of DAF-2 protein in the body wall muscles. hqSi10 previously known as hq375. Reference: Zhang Y, et al. BioRxiv. 2021 Aug 2. 2007.2031.454567. https:|"Made_by: Yan-Ping Zhang, Wen-Hong Zhang" WBGene00000898(daf-2)|WBGene00006843(unc-119) WBGene00000898(daf-2), WBGene00006843(unc-119) WB-STRAIN:WBStrain00051781 WormBase (WB) WB unknown WormBase 2026-10-10 11:02:35 0
hqSi9 II; daf-2(hq363[daf-2::degron::mNeonGreen]) unc-119(ed3) III.
 
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RRID:WB-STRAIN:WBStrain00051780 Caenorhabditis elegans hqSi9 II; daf-2(hq363[daf-2::degron::mNeonGreen]) unc-119(ed3) III. hqSi9 [dpy-7p::TIR1::mRuby::unc-54 3UTR + Cbr-unc-119(+)] II. Degron and mNeonGreen tag inserted at the 3' end of the endogenous daf-2 gene locus by CRISPR/Cas9 engineering. hqSi9 was generated by replacing the eft-3 promoter of the ieSi57 insertion (oxTi179 site) with the dpy-7 promoter using CRISPR/Cas9. This strain can be used for auxin-inducible degradation (AID) of DAF-2 protein in the hypodermis. hqSi9 previously known as hq374. Reference: Zhang Y, et al. BioRxiv. 2021 Aug 2. 2007.2031.454567. https:|"Made_by: Yan-Ping Zhang, Wen-Hong Zhang" WBGene00000898(daf-2)|WBGene00006843(unc-119) WBGene00000898(daf-2), WBGene00006843(unc-119) WB-STRAIN:WBStrain00051780 WormBase (WB) WB unknown WormBase 2026-10-10 11:02:35 0
ieSi57 II; daf-2(hq363[daf-2::degron::mNeonGreen]) unc-119(ed3) III.
 
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RRID:WB-STRAIN:WBStrain00051786 Caenorhabditis elegans ieSi57 II; daf-2(hq363[daf-2::degron::mNeonGreen]) unc-119(ed3) III. ieSi57 [eft-3p::TIR1::mRuby::unc-54 3' UTR + Cbr-unc-119(+)] II. Degron and mNeonGreen tag inserted at the 3' end of the endogenous daf-2 gene locus by CRISPR/Cas9 engineering. A single copy transgene was inserted into chromosome II (oxTi179) expressing modified Arabidopsis thaliana TIR1 tagged with mRuby in the soma. This strain can be used for auxin-inducible degradation (AID) of DAF-2 protein in somatic tissues. Reference: Zhang Y, et al. BioRxiv. 2021 Aug 2. 2007.2031.454567. https:|"Made_by: Yan-Ping Zhang, Wen-Hong Zhang" WBGene00000898(daf-2)|WBGene00006843(unc-119) WBGene00000898(daf-2), WBGene00006843(unc-119) WB-STRAIN:WBStrain00051786 WormBase (WB) WB unknown WormBase 2026-10-10 11:02:35 0
daf-16(hq389[daf-16::gfp::degron]) I; hqSi8 II; daf-2(e1370) unc-119(ed3) III.
 
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RRID:WB-STRAIN:WBStrain00051789 Caenorhabditis elegans daf-16(hq389[daf-16::gfp::degron]) I; hqSi8 II; daf-2(e1370) unc-119(ed3) III. hqSi8 [rgef-1p::TIR1::mRuby::unc-54 3UTR+Cbr-unc-119(+)] II. Maintain at 15C. GFP tag and degron inserted at the 3' end of the endogenous daf-16 gene locus by CRISPR/Cas9 engineering. hqSi8 was generated by replacing the eft-3 promoter of the ieSi57 insertion (oxTi179 site) with the rgef-1 promoter using CRISPR/Cas9. This strain can be used for auxin-inducible degradation (AID) of DAF-16 protein in the neurons. hqSi8 previously known as hq373. Reference: Zhang Y, et al. BioRxiv. 2021 Aug 2. 2007.2031.454567. https:|"Made_by: Yan-Ping Zhang, Wen-Hong Zhang" WBGene00000898(daf-2)|WBGene00000912(daf-16)|WBGene00006843(unc-119) WBGene00000898(daf-2), WBGene00000912(daf-16), WBGene00006843(unc-119) WB-STRAIN:WBStrain00051789 WormBase (WB) WB unknown WormBase 2026-10-10 11:02:35 0
unc-119(ed3) III; stxEx35.
 
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RRID:WB-STRAIN:WBStrain00051957 Caenorhabditis elegans unc-119(ed3) III; stxEx35. stxEx35 [istr-1::TY1::eGFP::3xFLAG + Cbr-unc-119(+)]. Pick non-Unc to maintain. Constitutive expression of GFP. TY1::EGFP::3xFLAG tag inserted in frame at C-terminus of istr-1 coding sequence in fosmid WRM0636D_F01 by recombineering (TransgeneOme bacterial clone 5438954842362824 D10). Reference: Radetskaya O, et al. The PMK-3 (p38) Mitochondrial Retrograde Response Functions in Intestinal Cells to Extend Life via the ESCRT Machinery. bioRxiv 797308; doi: https: WBGene00006843(unc-119) WBGene00006843(unc-119) WB-STRAIN:WBStrain00051957 WormBase (WB) WB unknown WormBase 2026-10-10 11:02:37 0
juSi164 unc-119(ed3) III; wtfIs263.
 
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RRID:WB-STRAIN:WBStrain00062210 Caenorhabditis elegans juSi164 unc-119(ed3) III; wtfIs263. juSi164 [mex-5p::HIS-72::miniSOG + Cbr-unc-119(+)] III. wtfIs263 [rab-3p::AI::ChR2(H134R)::unc-54 3'UTR + rab-3p::AI::Voltron::unc-54 3'UTR + rab-3p::his-24::tagBFP::unc-54 3'UTR]. Keep plates covered to avoid unnecessary exposure to light. Pan-neuronal expression of ChR2 (H134R) along with Voltron volatage indicator and nuclear-localized tagBFP. Reporter construct contains an artificial intron (AI). Reference: Sharma AK, et al. Genetics 2024 May 11:iyae077. doi: 10.1093/genetics/iyae077 PMID: 38733622. WBGene00006843(unc-119) WBGene00006843(unc-119) WB-STRAIN:WBStrain00062210 WormBase (WB) WB unknown WormBase 2026-10-10 11:05:09 0
juSi164 unc-119(ed3) III; wtfIs335.
 
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RRID:WB-STRAIN:WBStrain00062213 Caenorhabditis elegans juSi164 unc-119(ed3) III; wtfIs335. juSi164 [mex-5p::HIS-72::miniSOG + Cbr-unc-119(+)] III. wtfIs335 [5xQUAS+(delta)pes-10p::AI::eTsChR::unc-54 3'UTR + rab-3p::AI::QF+hGR::SL2::tagBFP::unc-54 3'UTR + rab-3p::his-24::tagRFP::unc-54 3'UTR + rab-3p::his-24::GCaMP6s::unc-54 3'UTR]. Keep plates covered to avoid unnecessary exposure to light. Pan-neuronal eTsChR on activation using dex treatment via QF+hGR. Worms also express calcium sensing fluorescence protein- GCaMP6s in nuclei of each neurons. Reporter construct contains an artificial intron (AI). Reference: Sharma AK, et al. Genetics 2024 May 11:iyae077. doi: 10.1093/genetics/iyae077 PMID: 38733622. WBGene00006843(unc-119) WBGene00006843(unc-119) WB-STRAIN:WBStrain00062213 WormBase (WB) WB unknown WormBase 2026-10-10 11:05:09 0

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