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Integrated Animals is a virtual database currently indexing available animal strains and mutants from: AGSC (Ambystoma), BCBC (mice), BDSC (flies), European Xenopus Resource Center (frog), The National Xenopus Resource (frog), Xenopus Express (frog), CWRU Cystic Fibrosis Mouse Models (mice), DGGR (flies), FlyBase (flies), IMSR (mice), MGI (mice), MMRRC (mice), NSRRC (pig), RGD (rats), Sperm Stem Cell Libraries for Biological Research (rats), Tetrahymena Stock Center (Tetrahymena), WormBase (worms), XGSC (Xiphophorus), ZFIN (zebrafish), and ZIRC (zebrafish). Note, the IMSR data is linked, but users may need to re-execute the search if the top mouse is not returned properly.
Note: BCBC is no longer in service, so the links may not be functional.
| Organism Name | Proper Citation | Species | Synonyms |
Notes |
Phenotype | Affected Gene | |||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
SD-Dmdem1Ang Resource Report Resource Website |
RRID:RGD_12880037 | Rattus norvegicus | This mutant strain was generated by injecting TALEN targeting exon23 of rat Dmd into Crl:SD embryo. The resulting mutant is a 11 bp-deletion in exon 23 leading to a +1 grame shift and premature stop codon 81 bp after the mutation. | 12880037 | mutant | Rat Genome Database (RGD) | RGD | Unknown | 12880037 | RGD | 2026-11-07 12:23:26 | 0 | |||||
|
SD-Apoeem1Sage Resource Report Resource Website |
RRID:RGD_12880021 | Rattus norvegicus | The mutant rat strain was produced by injecting zinc endonuclease targeting the exon 3 of rat Apoe into Sprague Dawley embryos. This mutant rat has a 16-bp deletion in the gene and resulted in complete loss of Apoe protein in homozygotes. Horizon Discovery | 12880021 | mutant | Rat Genome Database (RGD) | RGD | Live Animals (as of 2017-05-01) | 12880021 | RGD | 2026-11-07 12:23:26 | 0 | |||||
|
WKY-Cyp2j4em1Sage/Tja Resource Report Resource Website 1+ mentions |
RRID:RGD_12904679 | Rattus norvegicus | ZFN system was used to introduce a 25-bp deletion mutation in the exon 4 of Cyp2j4 gene of WKY/NCrl rat embryos. This deletion results in premature stop of protein translation. | 12904679 | mutant | Rat Genome Database (RGD) | RGD | Unknown | 12904679 | RGD | 2026-11-07 12:23:25 | 1 | |||||
|
F344-Hsd11b2em1Jmul-/- Resource Report Resource Website |
RRID:RGD_13800556 | Rattus norvegicus | The ZFN system targeting exon 2 of Hsd11b2 gene was injected into the F344/IcoCrl embryos to induce a 123-bp deletion removing the 3' end of exon 2 and the first 16-bp of intron B and create a premature stop coden TAG. | 13800556 | mutant | Rat Genome Database (RGD) | RGD | Unknown | 13800556 | RGD | 2026-11-07 12:23:26 | 0 | |||||
|
SD-Mmp12em2Soar Resource Report Resource Website |
RRID:RGD_12910505 | Rattus norvegicus | TALEN mediated 607 bp deletion that includes exon 2 of the Mmp12 gene, resulting in a frameshift and premature stop codon | 12910505 | mutant | Rat Genome Database (RGD) | RGD | Unknown | 12910505 | RGD | 2026-11-07 12:23:25 | 0 | |||||
|
SD-Abcg2em1Sage Resource Report Resource Website |
RRID:RGD_12904063 | Rattus norvegicus | This ZFN model carries a 588-bp deletion within Abcg2 gene. Homozygous knockouts display total loss of protein via Western blot Horizon Discovery | 12904063 | mutant | Rat Genome Database (RGD) | RGD | Live Animals (as of 2017-05-16) | 12904063 | RGD | 2026-11-07 12:23:26 | 0 | |||||
|
F344-Hsd11b2em1Jmul+/+ Resource Report Resource Website 1+ mentions |
RRID:RGD_13800557 | Rattus norvegicus | This is the wild-type litter mates of the Hsd11b2 F344 mutants created by ZFN system targeting exon 2 of Hsd11b2 gene was injected into the F344/IcoCrl embryos to induce a 123-bp deletion removing the 3' end of exon 2 and the first 16-bp of intron B and create a premature stop coden TAG. | 13800557 | mutant | Rat Genome Database (RGD) | RGD | Unknown | 13800557 | RGD | 2026-11-07 12:23:26 | 1 | |||||
|
SS.BN-(D13Hmgc1048-D13Hmgc1050)-Pappa2em4Mcwi Resource Report Resource Website |
RRID:RGD_13204756 | Rattus norvegicus | CRISPR/Cas9 system was used to introduce a 5-bp deletion in exon 2 of the rat Pappa2 gene of SS.BN-(D13Hmgc1048-D13Hmgc1050)/Mcwi rat embryos. Contact MCW rat distribution at [email protected] | 13204756 | mutant | Rat Genome Database (RGD) | RGD | Cryopreserved Sperm (as of 2021-11-03) | 13204756 | RGD | 2026-11-07 12:23:25 | 0 | |||||
|
FHH-Mybphlem1Mcwi Resource Report Resource Website |
RRID:RGD_13800838 | Rattus norvegicus | CRISPR/Cas9 system was used to introduce a 2-bp deletion in exon 1 of rat Mybphl gene in the FHH/EurMcwi embryos. Contact MCW rat distribution at [email protected] | 13800838 | mutant | Rat Genome Database (RGD) | RGD | Cryopreserved Sperm (as of 2021-11-03) | 13800838 | RGD | 2026-11-07 12:23:26 | 0 | |||||
|
SD-Sncaem1Sage Resource Report Resource Website |
RRID:RGD_13782164 | Rattus norvegicus | This model contains a deletion of the endogenous rat SNCA gene, encoding the alpha-synuclein protein. This model was generated using the CRISPR/Cas9 genome targeting strategy. Horizon Discovery | 13782164 | mutant | Rat Genome Database (RGD) | RGD | Live Animals (as of 2018-08-24) | 13782164 | RGD | 2026-11-07 12:23:26 | 0 | |||||
|
SD-Sncatm1(SNCA*)Sage Resource Report Resource Website |
RRID:RGD_13782163 | Rattus norvegicus | This model contains a knockin of the A53T-mutated SNCA gene deeming the rat SNCA gene non-functional. The knockin contains humanized amino acids for the region spanning amino acids 53-122. The resulting model expresses a humanized A53T alpha-synuclein protein without endogenous rat alpha-synuclein. Horizon Discovery | 13782163 | mutant | Rat Genome Database (RGD) | RGD | Live Animals (as of 2018-08-24) | 13782163 | RGD | 2026-11-07 12:23:26 | 0 | |||||
|
SD-Abcb1aem1Sage -/- Resource Report Resource Website |
RRID:RGD_12904057 | Rattus norvegicus | This ZFN model contains biallelic 20 bp deletion within Abcba1 gene. Animals exhibit increased oral bioavailability of P-gp-specific substrates. The homozygous knockout rats display total loss of protein via Western blot. Horizon Discovery | 12904057 | mutant | Rat Genome Database (RGD) | RGD | Live Animals (as of 2017-05-16) | 12904057 | RGD | 2026-11-07 12:23:26 | 0 | |||||
|
FHH-Muc1em1Mcwi Resource Report Resource Website |
RRID:RGD_13800825 | Rattus norvegicus | CRISPR/Cas9 system was used to introduce a 2-bp deletion in exon 2 of rat Muc1 gene in the FHH/EurMcwi embryos. Contact MCW rat distribution at [email protected] | 13800825 | mutant | Rat Genome Database (RGD) | RGD | Cryopreserved Sperm (as of 2018-10-18) | 13800825 | RGD | 2026-11-07 12:23:26 | 0 | |||||
|
SD-(Abcb1a- Abcb1b)em1Sage Resource Report Resource Website |
RRID:RGD_12904059 | Rattus norvegicus | This model carries knockout of Abcb1a and Abcb1b. Horizon Discovery | 12904059 | mutant | Rat Genome Database (RGD) | RGD | Live Animals (as of 2017-05-16) | 12904059 | RGD | 2026-11-07 12:23:26 | 0 | |||||
|
BN-Crb1m1 Resource Report Resource Website |
RRID:RGD_13451132 | Rattus norvegicus | This Brown Norway from Janvier rat strain spontaneously develops progressive focal retinal layer disorganization, loss of photoreceptors, cystic cavitation, and RMG abnormalities associated with early retinal vascular telangiectasia and late stage subretinal neovascularization. This phenotype bears reminiscent of human Macular telangiectasia 2. A deletion insertion mutation in exon 6 of the rat crb1 was identified to be responsible for this retinal phenotype. | 13451132 | mutant | Rat Genome Database (RGD) | RGD | Unknown | 13451132 | RGD | 2026-11-07 12:23:26 | 0 | |||||
|
LEW-Chrnb4em5Mcwi Resource Report Resource Website |
RRID:RGD_13207488 | Rattus norvegicus | CRISPR/Cas9 system was used to introduce a mutation in the Chrnb4 gene of LEW/NCrl rat embryos. The resulting mutation is a 4-bp deletion of exon 4 in the Chrnb4 gene. Contact MCW rat distribution at [email protected] | 13207488 | mutant | Rat Genome Database (RGD) | RGD | Cryopreserved Sperm (as of 2021-11-03) | 13207488 | RGD | 2026-11-07 12:23:25 | 0 | |||||
|
SD-Nr1i2em1Sage Nr1i3em1Sage Ahrem1Sage Resource Report Resource Website 1+ mentions |
RRID:RGD_12903272 | Rattus norvegicus | This model contains three knockout genes, the 20-bp deletion within rat Nr1i2, the ZFN-induced 10-bp deletion within rat Nr1i3 gene and the 760-bp deletion in the rat Ahr gene. Horizon Discovery | 12903272 | mutant | Rat Genome Database (RGD) | RGD | Cryopreserved Embryo (as of 2017-05-10) | 12903272 | RGD | 2026-11-07 12:23:26 | 1 | |||||
|
SS-Kcnq1em5Mcwi Resource Report Resource Website |
RRID:RGD_13800810 | Rattus norvegicus | CRISPR/Cas9 system and the single-stranded oligodeoxynucleotide (ssODN ) were combined to introduce the R231H mutation in the Kcnq1 gene of SS/JrHsdMcwi rat embryos. Contact MCW rat distribution at [email protected] | 13800810 | mutant | Rat Genome Database (RGD) | RGD | Cryopreserved Embryo; Cryopreserved Sperm (as of 2018-10-18) | 13800810 | RGD | 2026-11-07 12:23:26 | 0 | |||||
|
SD-Trpv1em1Sage+/+ Resource Report Resource Website |
RRID:RGD_13792705 | Rattus norvegicus | These ZFN mutant rats were produced by injecting zinc finger nuclease targeting exon 13 of rat Trpv1 into Sprague Dawley embryos. A 2-bp (CA) frameshift deletion in exon 13 was created ( SD-Trpv1em1Sage-/-). This wild type mutant is the wild type offspring from the cross of heterozygous mutants. | 13792705 | mutant | Rat Genome Database (RGD) | RGD | Unknown | 13792705 | RGD | 2026-11-07 12:23:26 | 0 | |||||
|
SD-Trpv1em1Sage-/- Resource Report Resource Website |
RRID:RGD_13792701 | Rattus norvegicus | These ZFN mutant rats were produced by injecting zinc finger nuclease targeting exon 13 of rat Trpv1 into Sprague Dawley embryos. A 2-bp (CA) frameshift deletion in exon 13 was created. Homozygous knockout rats exhibit complete loss of Trpv1 protein. Horizon Discovery | 13792701 | mutant | Rat Genome Database (RGD) | RGD | Cryopreserved Embryo (as of 2018-09-21) | 13792701 | RGD | 2026-11-07 12:23:26 | 0 |
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