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Integrated Animals is a virtual database currently indexing available animal strains and mutants from: AGSC (Ambystoma), BCBC (mice), BDSC (flies), European Xenopus Resource Center (frog), The National Xenopus Resource (frog), Xenopus Express (frog), CWRU Cystic Fibrosis Mouse Models (mice), DGGR (flies), FlyBase (flies), IMSR (mice), MGI (mice), MMRRC (mice), NSRRC (pig), RGD (rats), Sperm Stem Cell Libraries for Biological Research (rats), Tetrahymena Stock Center (Tetrahymena), WormBase (worms), XGSC (Xiphophorus), ZFIN (zebrafish), and ZIRC (zebrafish). Note, the IMSR data is linked, but users may need to re-execute the search if the top mouse is not returned properly.
Note: BCBC is no longer in service, so the links may not be functional.
http://www.wormbase.org/db/get?name=WBStrain00008416
Source Database: WormBase (WB)
Affected Genes: WBGene00006850(unc-127)
Genomic Alteration: WBGene00006850(unc-127)
Availability: available
Source References: PMID:8984009
Synonyms: unc-127(hs13) V.
Alternate IDs: WB-STRAIN:HH27, CGC_HH27
Notes: Cold sensitive coiler Unc.|"Made_by: William Jones"
Proper citation: RRID:WB-STRAIN:WBStrain00008416 Copy
http://www.wormbase.org/db/get?name=WBStrain00008418
Source Database: WormBase (WB)
Affected Genes: WBGene00006749(unc-9)
Genomic Alteration: WBGene00006749(unc-9)
Availability: available
Source References: PMID:8984009
Synonyms: unc-9(hs6) X.
Alternate IDs: WB-STRAIN:HH29, CGC_HH29
Notes: Cold sensitive Unc.|"Made_by: William Jones"
Proper citation: RRID:WB-STRAIN:WBStrain00008418 Copy
http://www.wormbase.org/db/get?name=WBStrain00008448
Source Database: WormBase (WB)
Affected Genes: WBGene00000254(bli-4)|WBGene00003217(mel-44)|WBGene00006873(vab-7)
Genomic Alteration: WBGene00000254(bli-4), WBGene00003217(mel-44), WBGene00006873(vab-7)
Availability: available
Source References: PMID:9409829
Synonyms: +/hT2 I; vab-7(e1562) mel-44(sb44)/hT2 [bli-4(e937) let-?(h661)] III.
Alternate IDs: WB-STRAIN:HR492, CGC_HR492
Notes: Dominant ts maternal-effect embryonic lethal. Embryos arrest prior to morphogenesis or at two-fold. Non-ts recessive mid-larval lethal. Maintain at 15C. Freezes poorly.
Proper citation: RRID:WB-STRAIN:WBStrain00008448 Copy
http://www.wormbase.org/db/get?name=WBStrain00008450
Source Database: WormBase (WB)
Affected Genes: WBGene00001079(dpy-20)|WBGene00003216(memi-1)
Genomic Alteration: WBGene00001079(dpy-20), WBGene00003216(memi-1)
Availability: available
Source References: PMID:9409829
Synonyms: memi-1(sb41) dpy-20(e1282)/nT1 [unc-?(n754) let-?] IV; +/nT1 V.
Alternate IDs: WB-STRAIN:HR592, CGC_HR592
Notes: Dominant ts maternal-effect embryonic lethal. Embryos show extensive cytoplasmic blebbing, often accompanied by small spindles and incomplete cytokinesis. Two cell embryos divide synchronously. Embryos arrest with eight to several hundred cells. Recessive non-ts maternal-effect embryonic lethal. Null may be WT. Maintain at 15C.
Proper citation: RRID:WB-STRAIN:WBStrain00008450 Copy
http://www.wormbase.org/db/get?name=WBStrain00008451
Source Database: WormBase (WB)
Availability: available
Synonyms: sbEx133.
Alternate IDs: WB-STRAIN:HR596, CGC_HR596
Notes: sbEx133 [mel-11::GFP + rol-6(su1006)]. Maintain by picking Rollers.
Proper citation: RRID:WB-STRAIN:WBStrain00008451 Copy
http://www.wormbase.org/db/get?name=WBStrain00008454
Source Database: WormBase (WB)
Affected Genes: WBGene00003056(lon-2)
Genomic Alteration: WBGene00003056(lon-2)
Availability: available
Synonyms: +/szT1 [lon-2(e678)] I; syDf1/szT1 X.
Alternate IDs: WB-STRAIN:HR890, CGC_HR890
Notes: Heterozygotes are Lon and segregate Lon and dead eggs.
Proper citation: RRID:WB-STRAIN:WBStrain00008454 Copy
http://www.wormbase.org/db/get?name=WBStrain00008455
Source Database: WormBase (WB)
Affected Genes: WBGene00006529(tba-2)|WBGene00006829(unc-101)
Genomic Alteration: WBGene00006529(tba-2), WBGene00006829(unc-101)
Availability: available
Synonyms: unc-101(m1) tba-2(sb25) I.
Alternate IDs: WB-STRAIN:HR899, CGC_HR899
Notes: Unc.
Proper citation: RRID:WB-STRAIN:WBStrain00008455 Copy
http://www.wormbase.org/db/get?name=WBStrain00008456
Source Database: WormBase (WB)
Affected Genes: WBGene00000421(ced-7)|WBGene00001076(dpy-17)
Genomic Alteration: WBGene00000421(ced-7), WBGene00001076(dpy-17)
Availability: available
Synonyms: ced-7(n1829) dpy-17(e164) III.
Alternate IDs: WB-STRAIN:HR961, CGC_HR961
Notes: Dpy. Maternal effect persistent cell corpses. This was derived from MT4993; it was outcrossed once to get rid of an unlinked lethal. Hatching rate has improved from 10-70% to 98%.
Proper citation: RRID:WB-STRAIN:WBStrain00008456 Copy
http://www.wormbase.org/db/get?name=WBStrain00008437
Source Database: WormBase (WB)
Availability: available
Source References: PMID:37639584
Synonyms: khIs22.
Alternate IDs: WB-STRAIN:HK205, CGC_HK205
Notes: khIs22[(pRRG4824L) unc-68::GFP + rol-6(su1006)]. Rollers.|"Supplementary_genotype KhIs22 [(pRRG4824L) unc-68p::gfp + rol-6(su1006)]"
Proper citation: RRID:WB-STRAIN:WBStrain00008437 Copy
http://www.wormbase.org/db/get?name=WBStrain00008439
Source Database: WormBase (WB)
Affected Genes: WBGene00003085(ccar-1)
Genomic Alteration: WBGene00003085(ccar-1)
Availability: available
Synonyms: ccar-1(sda11) IV.
Alternate IDs: WB-STRAIN:HMZ245, CGC_HMZ245
Notes: Superficially wild-type except for a slightly shorter body length in adults. Crispr/Cas9 was used to create a 13 bp deletion in exon7 of ccar-1a; breakpoints: CTGATTCGGGAG/sda11/ATCGGAAGTTTC. sda11 is an isoform-specific deletion allele. It only affects the function of CCAR-1A and CCAR-1D, but not CCAR-1B and C. In addition, because CCAR-1D is not expressed in embryos,this allele can be used to specifically inactivate CCAR-1A (the full-length isoform that is the most similar to human CCAR1) during embryogenesis. Reference: Fu R, et al. J Cell Sci. 2018 May 10.
Proper citation: RRID:WB-STRAIN:WBStrain00008439 Copy
http://www.wormbase.org/db/get?name=WBStrain00008440
Source Database: WormBase (WB)
Affected Genes: WBGene00004947(sos-1)
Genomic Alteration: WBGene00004947(sos-1)
Availability: available
Synonyms: sos-1(pd10) V.
Alternate IDs: WB-STRAIN:HP17, CGC_HP17
Notes: sos-1 gain-of-function allele originally isolated as a suppressor of sem-5(n1619) lethality. pd10 causes a E99K substitution within the N-terminal histone fold domain of SOS-1. Single mutants appear wild-type.
Proper citation: RRID:WB-STRAIN:WBStrain00008440 Copy
http://www.wormbase.org/db/get?name=WBStrain00008441
Source Database: WormBase (WB)
Affected Genes: WBGene00004947(sos-1)
Genomic Alteration: WBGene00004947(sos-1)
Availability: available
Synonyms: sos-1(pd9) V.
Alternate IDs: WB-STRAIN:HP23, CGC_HP23
Notes: sos-1(pd9) is a gain-of-function allele causing a C662Y substitution within the Ras exchange motif of SOS-1. Originally isolated as a suppressor of sem-5(n1619) lethality. Single mutants appear wild-type. Reference: Wooller A & Hopper N. (2014) European Worm Meeting. (Anyone using this allele may cite Neil Hopper as a personal communication based on this meeting abstract.)
Proper citation: RRID:WB-STRAIN:WBStrain00008441 Copy
http://www.wormbase.org/db/get?name=WBStrain00008444
Source Database: WormBase (WB)
Affected Genes: WBGene00003183(mei-1)|WBGene00006752(unc-13)|WBGene00006765(unc-29)
Genomic Alteration: WBGene00003183(mei-1), WBGene00006752(unc-13), WBGene00006765(unc-29)
Availability: available
Source References: PMID:2379819
Synonyms: mei-1(b284) unc-29(e1072)/mei-1(ct46) unc-13(e1091) I.
Alternate IDs: WB-STRAIN:HR75, CGC_HR75
Notes: Heterozygotes are WT. ct46 is a dominant, temperature sensitive maternal effect lethal. ct46 homozygotes are viable and fertile at 15C. b284 is a non-conditional, recessive maternal effect lethal. Heterozygotes give more viable progeny at 15C than 25C.|"Made_by: Kemphues/Mains"
Proper citation: RRID:WB-STRAIN:WBStrain00008444 Copy
http://www.wormbase.org/db/get?name=WBStrain00008589
Source Database: WormBase (WB)
Affected Genes: WBGene00001864(him-5)
Genomic Alteration: WBGene00001864(him-5)
Availability: available
Synonyms: him-5(e1490) V; bpIs37.
Alternate IDs: WB-STRAIN:HZ504, CGC_HZ504
Notes: bpIs37 [dcap-1p::dcap-1::DsRed + rol-6(su1006)]. Rollers. Translational DsRed reporter for the P body-specific marker dcap-1, which encodes the C. elegans ortholog of decapping complex component DCAP1. Low levels of expression are homogenously distributed in the cytoplasm at all stages of embryogenesis. Reference: Sun YY, et al. Protein Cell. 2011 Nov;2(11):918-39.|"Mutagen:Gamma radiation"
Proper citation: RRID:WB-STRAIN:WBStrain00008589 Copy
http://www.wormbase.org/db/get?name=WBStrain00008504
Source Database: WormBase (WB)
Affected Genes: WBGene00006808(unc-76)
Genomic Alteration: WBGene00006808(unc-76)
Availability: available
Synonyms: unc-76(e911) V; osEx397.
Alternate IDs: WB-STRAIN:HS2329, CGC_HS2329
Notes: osEx397 [cwn-1p::cwn-1::Venus + unc-76(+)]. Pick nonUnc to maintain. Transgene is expressed in tail region. Reference: Yamamoto et al. PLoS Genet. 2011 Oct;7(10):e1002308.
Proper citation: RRID:WB-STRAIN:WBStrain00008504 Copy
http://www.wormbase.org/db/get?name=WBStrain00008508
Source Database: WormBase (WB)
Affected Genes: WBGene00001072(dpy-10)|WBGene00001101(dsh-1)|WBGene00001102(dsh-2)|WBGene00003241(mig-5)
Genomic Alteration: WBGene00001072(dpy-10), WBGene00001101(dsh-1), WBGene00001102(dsh-2), WBGene00003241(mig-5)
Availability: available
Synonyms: dsh-2(or302) dsh-1(ok1445) mig-5(tm2639)/mIn1 [dpy-10(e128) mIs14] II.
Alternate IDs: WB-STRAIN:HS2725, CGC_HS2725
Notes: Heterozygotes are WT with pharyngeal GFP. Segregates WT GFP+, Dpy GFP+ (mIn1 homozygotes) and non-GFP triple homozygotes (mostly Emb with a few animals surviving to early L1). Pick WT GFP+ animals and check for correct segregation of progeny to maintain.
Proper citation: RRID:WB-STRAIN:WBStrain00008508 Copy
http://www.wormbase.org/db/get?name=WBStrain00008590
Source Database: WormBase (WB)
Affected Genes: WBGene00001864(him-5)
Genomic Alteration: WBGene00001864(him-5)
Availability: available
Source References: PMID:36774344, PMID:37118512, PMID:38483903, PMID:38963038, PMID:39117797
Synonyms: him-5(e1490) V; bpIs151 [sqst-1p::sqst-1::GFP:]
Alternate IDs: WB-STRAIN:HZ589, CGC_HZ589
Notes: bpIs151 [sqst-1p::sqst-1::GFP + unc-76(+)]. Him. In wild-type embryos, sqst-1::GFP is very weakly expressed and diffusely localized in the cytoplasm. Reference: Tian Y, et al. Cell. 2010 Jun 11;141(6):1042-55.|"Mutagen:Gamma radiation"
Proper citation: RRID:WB-STRAIN:WBStrain00008590 Copy
http://www.wormbase.org/db/get?name=WBStrain00008597
Source Database: WormBase (WB)
Affected Genes: WBGene00001864(him-5)|WBGene00021922(atg-3)
Genomic Alteration: WBGene00001864(him-5), WBGene00021922(atg-3)
Availability: available
Source References: PMID:32302543, PMID:37432924, PMID:39746999
Synonyms: atg-3(bp412) IV; him-5(e1490) V.
Alternate IDs: WB-STRAIN:HZ1684, CGC_HZ1684
Notes: Him; ~30% male.|"WBStrain mapped, WBPaper00059578 added based on AFP_Strain data."
Proper citation: RRID:WB-STRAIN:WBStrain00008597 Copy
http://www.wormbase.org/db/get?name=WBStrain00008599
Source Database: WormBase (WB)
Affected Genes: WBGene00001864(him-5)|WBGene00010882(atg-7)
Genomic Alteration: WBGene00001864(him-5), WBGene00010882(atg-7)
Availability: available
Synonyms: bnIs1 I; atg-7(bp411) IV; him-5(e1490) V.
Alternate IDs: WB-STRAIN:HZ1686, CGC_HZ1686
Notes: bnIs1 [pie-1p::GFP::pgl-1 + unc-119(+)] I. Him; ~30% male. Accumulation of GFP::PGL-1 aggregates in somatic cells in embryos.
Proper citation: RRID:WB-STRAIN:WBStrain00008599 Copy
http://www.wormbase.org/db/get?name=WBStrain00008579
Source Database: WormBase (WB)
Affected Genes: WBGene00001864(him-5)|WBGene00004945(sop-2)
Genomic Alteration: WBGene00001864(him-5), WBGene00004945(sop-2)
Availability: available
Synonyms: sop-2(bp186) II; him-5(e1490) bxIs16 V.
Alternate IDs: WB-STRAIN:HZ66, CGC_HZ66
Notes: bxIs16 [cat-2::YFP + tph-1::CFP]. Temperature sensitive: lethal at 25C. Maintain at 20C.
Proper citation: RRID:WB-STRAIN:WBStrain00008579 Copy
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