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Integrated Animals is a virtual database currently indexing available animal strains and mutants from: AGSC (Ambystoma), BCBC (mice), BDSC (flies), European Xenopus Resource Center (frog), The National Xenopus Resource (frog), Xenopus Express (frog), CWRU Cystic Fibrosis Mouse Models (mice), DGGR (flies), FlyBase (flies), IMSR (mice), MGI (mice), MMRRC (mice), NSRRC (pig), RGD (rats), Sperm Stem Cell Libraries for Biological Research (rats), Tetrahymena Stock Center (Tetrahymena), WormBase (worms), XGSC (Xiphophorus), ZFIN (zebrafish), and ZIRC (zebrafish). Note, the IMSR data is linked, but users may need to re-execute the search if the top mouse is not returned properly.
Note: BCBC is no longer in service, so the links may not be functional.
http://www.wormbase.org/db/get?name=WBStrain00008314
Source Database: WormBase (WB)
Availability: available
Synonyms: C10C6.7(goe5) IV.
Alternate IDs: WB-STRAIN:HBR764, CGC_HBR764
Notes: goe5 is a 4 bp deletion in the second exon causing a frame shift and presumptive molecular null allele. sgRNA target sequence: GTTATGGTGAGAAGGAAAGCtgg Reference: Turek et al. eLife 2016;5:e12499.|"Made_by: Lewandrowski & Turek"
Proper citation: RRID:WB-STRAIN:WBStrain00008314 Copy
http://www.wormbase.org/db/get?name=WBStrain00008315
Source Database: WormBase (WB)
Affected Genes: WBGene00002988(lim-6)
Genomic Alteration: WBGene00002988(lim-6)
Availability: available
Synonyms: lim-6(tm4836) X.
Alternate IDs: WB-STRAIN:HBR914, CGC_HBR914
Notes: Complete lack of behavioral quiescence during sleep. Reference: Turek et al. eLife 2016;5:e12499.
Proper citation: RRID:WB-STRAIN:WBStrain00008315 Copy
http://www.wormbase.org/db/get?name=WBStrain00008316
Source Database: WormBase (WB)
Affected Genes: WBGene00006843(unc-119)
Genomic Alteration: WBGene00006843(unc-119)
Availability: available
Synonyms: unc-119(ed3) III; goeEx361.
Alternate IDs: WB-STRAIN:HBR986, CGC_HBR986
Notes: goeEx361 [ceh-24p::ReaChr::mKate2::unc-54 3'UTR + unc-119(+)]. Pick non-Unc to maintain. Reporter expresses ReaChr with expression control mKate2. Reference: Schwarz J & Bringmann H. eLife 2017;10.7554/eLife.24846.
Proper citation: RRID:WB-STRAIN:WBStrain00008316 Copy
http://www.wormbase.org/db/get?name=WBStrain00008319
Source Database: WormBase (WB)
Availability: available
Synonyms: goeIs247.
Alternate IDs: WB-STRAIN:HBR1077, CGC_HBR1077
Notes: goeIs247 [ceh-24p::GCaMP6s::mKate2::unc-54 3'UTR + unc-119(+)]. Reporter expresses calcium sensor GCaMP6s with expression control mKate2. Reference: Schwarz J & Bringmann H. eLife 2017;10.7554/eLife.24846.
Proper citation: RRID:WB-STRAIN:WBStrain00008319 Copy
http://www.wormbase.org/db/get?name=WBStrain00008320
Source Database: WormBase (WB)
Availability: available
Synonyms: goeIs288.
Alternate IDs: WB-STRAIN:HBR1261, CGC_HBR1261
Notes: goeIs288 [flp-11p::mKate2::unc-54 3'UTR + unc-119(+)]. Low copy number insertion. Integration site unknown, but likely not in LG II. Reference: Turek et al. eLife 2016;5:e12499.
Proper citation: RRID:WB-STRAIN:WBStrain00008320 Copy
http://www.wormbase.org/db/get?name=WBStrain00008321
Source Database: WormBase (WB)
Availability: available
Synonyms: mihp-2(syb235) V.
Alternate IDs: WB-STRAIN:HBR1971, CGC_HBR1971
Notes: Complete CRISPR/Cas-9 knock-out (2317bp deletion) of the gene nlp-42(Y80D3A.10). Two times backcrossed with N2. Homozygous. Superficial wild-type.|"Complete CRISPR/Cas-9 knock-out (2317bp deletion) of the gene nlp-42(Y80D3A.10). Two times backcrossed with N2. Homozygous. Superficial wild-type.Primers for crossing: Fwd: cgagacttttaaccccgtcgInFwd: aaagcccatgacttgctgaaRev: gctcaggtggttagagggttWild-type bands: 580bp, 2652bp. Mutation band: 335bp."|"Made_by: SunyBiotech Corperation"
Proper citation: RRID:WB-STRAIN:WBStrain00008321 Copy
http://www.wormbase.org/db/get?name=WBStrain00008501
Source Database: WormBase (WB)
Affected Genes: WBGene00001072(dpy-10)|WBGene00001102(dsh-2)|WBGene00003241(mig-5)
Genomic Alteration: WBGene00001072(dpy-10), WBGene00001102(dsh-2), WBGene00003241(mig-5)
Availability: available
Synonyms: dsh-2(or302) mig-5(tm2639)/mIn1 [dpy-10(e128) mIs14] II.
Alternate IDs: WB-STRAIN:HS1795, CGC_HS1795
Notes: Heterozygotes are WT with pharyngeal GFP. Segregates WT GFP+, Dpy GFP+ (mIn1 homozygotes) and few GFP- dsh-2(or302) mig-5(tm2639) homozygotes (Sys). Pick WT GFP+ animals and check for correct segregation of progeny to maintain.
Proper citation: RRID:WB-STRAIN:WBStrain00008501 Copy
http://www.wormbase.org/db/get?name=WBStrain00008469
Source Database: WormBase (WB)
Affected Genes: WBGene00001864(him-5)|WBGene00006808(unc-76)
Genomic Alteration: WBGene00001864(him-5), WBGene00006808(unc-76)
Availability: available
Synonyms: him-5(e1467) unc-76(e911) V; osEx67.
Alternate IDs: WB-STRAIN:HS321, CGC_HS321
Notes: osEx67 [psa-4::GFP + unc-76(+)]. Maintain by picking non-Unc. Reference: Sawa H, et al. Mol Cell. 2000 Sep;6(3):617-24.
Proper citation: RRID:WB-STRAIN:WBStrain00008469 Copy
http://www.wormbase.org/db/get?name=WBStrain00008470
Source Database: WormBase (WB)
Affected Genes: WBGene00001864(him-5)|WBGene00006808(unc-76)
Genomic Alteration: WBGene00001864(him-5), WBGene00006808(unc-76)
Availability: available
Synonyms: him-5(e1467) unc-76(e911) V; osEx71.
Alternate IDs: WB-STRAIN:HS325, CGC_HS325
Notes: osEx71 [psa-1::GFP + unc-76(+)]. Maintain by picking non-Unc. Reference: Sawa H, et al. Mol Cell. 2000 Sep;6(3):617-24.
Proper citation: RRID:WB-STRAIN:WBStrain00008470 Copy
http://www.wormbase.org/db/get?name=WBStrain00008460
Source Database: WormBase (WB)
Affected Genes: WBGene00000254(bli-4)|WBGene00001067(dpy-5)|WBGene00005077(src-1)
Genomic Alteration: WBGene00000254(bli-4), WBGene00001067(dpy-5), WBGene00005077(src-1)
Availability: available
Source References: PMID:38771761
Synonyms: src-1(cj293) dpy-5(e61)
Alternate IDs: WB-STRAIN:HR1275, CGC_HR1275
Notes: Heterozygotes are WT and segregate WT, Dpy Mels and dead eggs.
Proper citation: RRID:WB-STRAIN:WBStrain00008460 Copy
http://www.wormbase.org/db/get?name=WBStrain00008464
Source Database: WormBase (WB)
Affected Genes: WBGene00001864(him-5)|WBGene00003423(msi-1)
Genomic Alteration: WBGene00001864(him-5), WBGene00003423(msi-1)
Availability: available
Synonyms: msi-1(os1) III; him-5(e1490) V.
Alternate IDs: WB-STRAIN:HS144, CGC_HS144
Notes: 1.6 kb deletion in msi-1. Males have poor mating efficiency.|"Mutagen:UV/TMP"
Proper citation: RRID:WB-STRAIN:WBStrain00008464 Copy
http://www.wormbase.org/db/get?name=WBStrain00008466
Source Database: WormBase (WB)
Affected Genes: WBGene00009560(psa-3)
Genomic Alteration: WBGene00009560(psa-3)
Availability: available
Synonyms: psa-3(os8) X.
Alternate IDs: WB-STRAIN:HS178, CGC_HS178
Notes: Superficially WT. Defects in asymmetric T cell division causes Psa (phasmid socket absent) phenotype.
Proper citation: RRID:WB-STRAIN:WBStrain00008466 Copy
http://www.wormbase.org/db/get?name=WBStrain00008402
Source Database: WormBase (WB)
Affected Genes: WBGene00000090(age-1)|WBGene00000091(age-2)
Genomic Alteration: WBGene00000090(age-1), WBGene00000091(age-2)
Availability: available
Source References: PMID:10219000
Synonyms: age-2(yw23) I; age-1(hx546) II.
Alternate IDs: WB-STRAIN:HG284, CGC_HG284
Notes: This double mutant exhibits a doubling of both mean and maximum lifespans at 25C compared to N2. It exhibits a longer lifespan at 25C than it does at 20C. It has somewhat reduced fertility. It has normal development time, appearance, movements and feeding behavior. It's swimming rate in liquid is slightly higher than N2. STS mapping indicates the most likely location for age-2 is on LG I.
Proper citation: RRID:WB-STRAIN:WBStrain00008402 Copy
http://www.wormbase.org/db/get?name=WBStrain00008404
Source Database: WormBase (WB)
Affected Genes: WBGene00001609(glp-1)
Genomic Alteration: WBGene00001609(glp-1)
Availability: available
Synonyms: glp-1(e2141) III; lynEx1.
Alternate IDs: WB-STRAIN:HGA8002, CGC_HGA8002
Notes: lynEx1 [(pJG01)nhr-80p::nhr-80::GFP + myo-2p::DsRed]. Sterile at 25C. Maintain at 20C or lower. Pick animals with red pharynx to maintain. Lifespan of animals carrying the array is longer than that of glp-1 alone. Reference: Goudeau J, et al. PLoS Biol. 2011 Mar;9(3):e1000599.
Proper citation: RRID:WB-STRAIN:WBStrain00008404 Copy
http://www.wormbase.org/db/get?name=WBStrain00008405
Source Database: WormBase (WB)
Affected Genes: WBGene00001609(glp-1)|WBGene00003670(nhr-80)
Genomic Alteration: WBGene00001609(glp-1), WBGene00003670(nhr-80)
Availability: unknown
Synonyms: glp-1(e2141) nhr-80(tm1011) III; lynEx1.
Alternate IDs: WB-STRAIN:HGA8003
Notes: lynEx1 [(pJG01)nhr-80p::nhr-80::GFP + myo-2p::DsRed]. Sterile at 25C. Maintain at 20C or lower. Pick animals with red pharynx to maintain. lynEx1 fully rescues nhr-80(tm1011). Reference: Goudeau J, et al. PLoS Biol. 2011 Mar;9(3):e1000599.
Proper citation: RRID:WB-STRAIN:WBStrain00008405 Copy
http://www.wormbase.org/db/get?name=WBStrain00008406
Source Database: WormBase (WB)
Affected Genes: WBGene00000912(daf-16)|WBGene00001609(glp-1)
Genomic Alteration: WBGene00000912(daf-16), WBGene00001609(glp-1)
Availability: available
Synonyms: daf-16(mu86) I; glp-1(e2141) III; lynEx1.
Alternate IDs: WB-STRAIN:HGA8004, CGC_HGA8004
Notes: lynEx1 [(pJG01)nhr-80p::nhr-80::GFP + myo-2p::DsRed]. Sterile at 25C. Maintain at 20C or lower. Pick animals with red pharynx to maintain. Lifespan of animals carrying the array is longer than that of daf-16; glp-1 double mutants. Reference: Goudeau J, et al. PLoS Biol. 2011 Mar;9(3):e1000599.
Proper citation: RRID:WB-STRAIN:WBStrain00008406 Copy
http://www.wormbase.org/db/get?name=WBStrain00008407
Source Database: WormBase (WB)
Affected Genes: WBGene00000908(daf-12)|WBGene00001609(glp-1)
Genomic Alteration: WBGene00000908(daf-12), WBGene00001609(glp-1)
Availability: available
Synonyms: glp-1(e2141) III; daf-12(rh61rh411) X; lynEx1.
Alternate IDs: WB-STRAIN:HGA8005, CGC_HGA8005
Notes: lynEx1 [(pJG01)nhr-80p::nhr-80::GFP + myo-2p::DsRed]. Sterile at 25C. Maintain at 20C or lower. Pick animals with red pharynx to maintain. Lifespan of animals carrying the array is longer than that of glp-1; daf-12 double mutants. Reference: Goudeau J, et al. PLoS Biol. 2011 Mar;9(3):e1000599.
Proper citation: RRID:WB-STRAIN:WBStrain00008407 Copy
http://www.wormbase.org/db/get?name=WBStrain00008490
Source Database: WormBase (WB)
Availability: available
Synonyms: osIs1.
Alternate IDs: WB-STRAIN:HS1337, CGC_HS1337
Notes: Mutagen:Gamma ray|"osIs1 [CYE-1::GFP (pMF101) + unc-76(+)]; probably integrated on LG II. This strain has Ste, Emb, Muv, Him phenotypes (probably dominant effects of the integration). Expression in many blast cells can be detected. Reference: Fujita et al. PLoS ONE 2, e407 (2007)."
Proper citation: RRID:WB-STRAIN:WBStrain00008490 Copy
http://www.wormbase.org/db/get?name=WBStrain00008491
Source Database: WormBase (WB)
Availability: available
Synonyms: osIs2.
Alternate IDs: WB-STRAIN:HS1339, CGC_HS1339
Notes: Mutagen:Gamma ray|"osIs2 [CYE-1::GFP (pMF101) + unc-76(+)]; probably integrated on LG X. No dominant phenotypes observed (see HS1337). Expression in many blast cells can be detected, but much weaker than osIs1. Reference: Fujita et al. PLoS ONE 2, e407 (2007)."
Proper citation: RRID:WB-STRAIN:WBStrain00008491 Copy
http://www.wormbase.org/db/get?name=WBStrain00008492
Source Database: WormBase (WB)
Affected Genes: WBGene00006808(unc-76)
Genomic Alteration: WBGene00006808(unc-76)
Availability: available
Synonyms: unc-76(e911) V; osEx233.
Alternate IDs: WB-STRAIN:HS1359, CGC_HS1359
Notes: osEx233 [scm::mig-5::venus + unc-76(+)]. Pick non-Unc to maintain. Reference: Mizumoto K, Sawa H. Dev Cell. 2007 Feb;12(2):287-99.
Proper citation: RRID:WB-STRAIN:WBStrain00008492 Copy
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