Searching the RRID Resource Information Network
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Integrated Animals is a virtual database currently indexing available animal strains and mutants from: AGSC (Ambystoma), BCBC (mice), BDSC (flies), European Xenopus Resource Center (frog), The National Xenopus Resource (frog), Xenopus Express (frog), CWRU Cystic Fibrosis Mouse Models (mice), DGGR (flies), FlyBase (flies), IMSR (mice), MGI (mice), MMRRC (mice), NSRRC (pig), RGD (rats), Sperm Stem Cell Libraries for Biological Research (rats), Tetrahymena Stock Center (Tetrahymena), WormBase (worms), XGSC (Xiphophorus), ZFIN (zebrafish), and ZIRC (zebrafish). Note, the IMSR data is linked, but users may need to re-execute the search if the top mouse is not returned properly.
Note: BCBC is no longer in service, so the links may not be functional.
| Organism Name | Proper Citation | Species | Synonyms |
Notes |
Phenotype | Affected Gene | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
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129S4/SvJae-Cd86tm1Shr/Mmnc Resource Report Resource Website |
RRID:MMRRC_010624-UNC | Mus musculus | Research areas: Immunology and Inflammation; Mutation Type: Targeted Mutation ; Collection: | paresis [MP:0000754]| hindlimb paralysis [MP:0000755]| demyelination [MP:0000921]| abnormal dorsal root ganglion morphology [MP:0000961]| abnormal humoral immune response [MP:0001800]| decreased IgG level [MP:0001805]| brain inflammation [MP:0001847]| muscular atrophy [MP:0002269]| abnormal nervous system morphology [MP:0003632]| increased autoantibody level [MP:0003725]| abnormal myelin sheath morphology [MP:0003871]| abnormal ventral spinal root morphology [MP:0003993]| abnormal dorsal spinal root morphology [MP:0003994]| decreased susceptibility to experimental autoimmune encephalomyelitis [MP:0004800]| increased susceptibility to autoimmune diabetes [MP:0004803]| decreased susceptibility to autoimmune diabetes [MP:0004804]| decreased regulatory T cell number [MP:0004974]| abnormal T cell proliferation [MP:0005094]| decreased T cell proliferation [MP:0005095]| abnormal action potential [MP:0005402]| abnormal nerve conduction [MP:0005403]| absent spleen germinal center [MP:0008474]| increased tumor necrosis factor secretion [MP:0008560]| decreased tumor necrosis factor secretion [MP:0008561]| increased interferon-gamma secretion [MP:0008566]| decreased interleukin-12 secretion [MP:0008664]| decreased nerve conduction velocity [MP:0008814]| decreased grip strength [MP:0010053] | Cd86 | 010624-UNC | Targeted Mutation | Mutant Mouse Resource and Research Center (MMRRC) | MMRRC | PMID:9075931 | MMRRC_10624-UNC, MMRRC_010624, MMRRC_1624 | 2026-09-12 06:42:28 | 0 | |||
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129S4/SvJae-Cd28tm1Shr/Mmucd Resource Report Resource Website |
RRID:MMRRC_010628-UCD | Mus musculus | Research areas: Immunology and Inflammation; Mutation Type: Targeted Mutation ; Collection: | increased length of allograft survival [MP:0004751]| abnormal CD8-positive [MP:0005010]| alpha beta T cell morphology [MP:0005095]| decreased T cell proliferation [MP:0005350]| increased susceptibility to autoimmune disorder [MP:0008075]| decreased CD4-positive [MP:0008568]| alpha beta T cell number [MP:0008688]| abnormal interleukin secretion [MP:0008750] | Cd28 | 010628-UCD | Targeted Mutation | Mutant Mouse Resource and Research Center (MMRRC) | MMRRC | PMID:11285307 | MMRRC_10628-UCD, MMRRC_010628, MMRRC_1628 | 2026-09-12 06:42:28 | 0 | |||
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B6;129S5-Slc26a5tm1Jnz/Mmnc Resource Report Resource Website |
RRID:MMRRC_010570-UNC | Mus musculus | Research areas: Cell Biology, Developmental Biology, Models for Human Disease, Neurobiology, Sensorineural; Mutation Type: Targeted Mutation ; Collection: | organ of Corti degeneration [MP:0000043]| decreased body weight [MP:0001262]| deafness [MP:0001967]| cochlear ganglion degeneration [MP:0002857]| cochlear hair cell degeneration [MP:0004362]| cochlear inner hair cell degeneration [MP:0004398]| abnormal cochlear outer hair cell morphology [MP:0004399]| cochlear outer hair cell degeneration [MP:0004404]| absent cochlear microphonics [MP:0004413]| decreased cochlear microphonics [MP:0004414]| decreased cochlear nerve compound action potential [MP:0004417]| abnormal Claudius cell morphology [MP:0004430]| absent cochlear outer hair cell electromotility [MP:0004436]| decreased cochlear outer hair cell electromotility [MP:0004437]| degeneration of organ of Corti supporting cells [MP:0004465]| short cochlear outer hair cells [MP:0004466]| abnormal distortion product otoacoustic emission [MP:0004736]| absent distortion product otoacoustic emissions [MP:0004737]| increased cochlear nerve compound action potential [MP:0004767]| impaired hearing [MP:0006325]| abnormal otoacoustic response [MP:0006336]| increased or absent threshold for auditory brainstem response [MP:0011967] | Slc26a5 | 010570-UNC | Targeted Mutation | Mutant Mouse Resource and Research Center (MMRRC) | MMRRC | PMID:12239568 PMID:15207913 PMID:15319415 |
MMRRC_10570-UNC, MMRRC_010570, MMRRC_157 | 2026-09-12 06:42:27 | 0 | |||
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129S4/SvJae-Icostm1Shr/Mmucd Resource Report Resource Website |
RRID:MMRRC_010627-UCD | Mus musculus | Research areas: Immunology and Inflammation; Mutation Type: Targeted Mutation ; Collection: | decreased IgG level [MP:0001805]| abnormal T cell differentiation [MP:0002145]| abnormal spleen germinal center morphology [MP:0002359]| abnormal immunoglobulin level [MP:0002490]| decreased IgE level [MP:0002492]| abnormal CD4-positive [MP:0005463]| alpha-beta T cell physiology [MP:0008495]| decreased IgG1 level [MP:0008496]| decreased IgG2a level [MP:0008502]| increased IgG3 level [MP:0008751] | Icos | 010627-UCD | Targeted Mutation | Mutant Mouse Resource and Research Center (MMRRC) | MMRRC | PMID:11343122 | MMRRC_10627-UCD, MMRRC_010627, MMRRC_1627 | 2026-09-12 06:42:28 | 0 | |||
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Izon ES cell line Tal1 clone 224 Resource Report Resource Website |
RRID:MMRRC_010597-UCD | Mus musculus | Research areas: Developmental Biology, Hematology, Neurobiology, Research Tools; Mutation Type: Targeted Mutation ; Collection: | Tal1 | 010597-UCD | Targeted Mutation | Mutant Mouse Resource and Research Center (MMRRC) | MMRRC | PMID:8861941 | MMRRC_10597-UCD, MMRRC_010597, MMRRC_1597 | 2026-09-12 06:42:27 | 0 | ||||
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Izon ES cell line Tal1 LacZ clone 71-1B1 Resource Report Resource Website |
RRID:MMRRC_010629-UCD | Mus musculus | Research areas: Developmental Biology, Hematology, Research Tools; Mutation Type: Targeted Mutation ; Collection: | Tal1lacZ | 010629-UCD | Targeted Mutation | Mutant Mouse Resource and Research Center (MMRRC) | MMRRC | PMID:9751762 | MMRRC_10629-UCD, MMRRC_010629, MMRRC_1629 | 2026-09-12 06:42:28 | 0 | ||||
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B6J.Cg-Aprttm1Jat Tg(pUR288)1Vij/Mmmh Resource Report Resource Website |
RRID:MMRRC_010589-MU | Mus musculus | Research areas: Apoptosis, Cancer, Cell Biology, Models for Human Disease, Research Tools; Mutation Type: Targeted Mutation ; Collection: CMGCC | decreased hematocrit [MP:0000208]| abnormal body weight [MP:0001259]| decreased body weight [MP:0001262]| weight loss [MP:0001263]| hunched posture [MP:0001505]| disheveled coat [MP:0001511]| polyuria [MP:0001762]| kidney inflammation [MP:0001859]| reduced fertility [MP:0001921]| postnatal lethality [MP:0002082]| premature death [MP:0002083]| abnormal kidney morphology [MP:0002135]| dilated renal tubules [MP:0002705]| nephrolithiasis [MP:0002708]| renal interstitial fibrosis [MP:0003215]| decreased kidney weight [MP:0003918]| renal fibrosis [MP:0003985]| renal tubular necrosis [MP:0004154]| kidney atrophy [MP:0004970]| decreased creatinine clearance [MP:0005558]| increased blood urea nitrogen level [MP:0005565]| crystalluria [MP:0009645]| renal tubule atrophy [MP:0011346]| decreased urine uric acid level [MP:0011424]| abnormal urine nucleoside level [MP:0011477]| cystolithiasis [MP:0011625]| kidney collecting duct atrophy [MP:0011844]| increased fluid intake [MP:0011941] | |Aprt|pUR288| | 010589-MU | Targeted Mutation | Mutant Mouse Resource and Research Center (MMRRC) | MMRRC | PMID:8643571 PMID:8476606 PMID:8671725 |
MMRRC_10589-MU, MMRRC_010589, MMRRC_1589 | 2026-09-12 06:42:27 | 0 | |||
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129S4/SvJae-Cd80tm1Shr/Mmnc Resource Report Resource Website |
RRID:MMRRC_010623-UNC | Mus musculus | Research areas: Immunology and Inflammation; Mutation Type: Targeted Mutation ; Collection: | decreased cell proliferation [MP:0000352]| abnormal spleen morphology [MP:0000689]| decreased IgG level [MP:0001805]| brain inflammation [MP:0001847]| abnormal lymph node B cell domain morphology [MP:0002344]| abnormal T cell physiology [MP:0002444]| abnormal immunoglobulin level [MP:0002490]| increased IgM level [MP:0002494]| abnormal cytokine secretion [MP:0003009]| insulitis [MP:0004031]| increased susceptibility to experimental autoimmune encephalomyelitis [MP:0004799]| decreased susceptibility to experimental autoimmune encephalomyelitis [MP:0004800]| increased susceptibility to autoimmune diabetes [MP:0004803]| decreased susceptibility to autoimmune diabetes [MP:0004804]| decreased regulatory T cell number [MP:0004974]| decreased double-positive T cell number [MP:0005092]| decreased B cell proliferation [MP:0005093]| abnormal T cell proliferation [MP:0005094]| decreased T cell proliferation [MP:0005095]| increased T cell proliferation [MP:0005348]| abnormal CD4-positive [MP:0005463]| alpha-beta T cell physiology [MP:0005623]| abnormal meninges morphology [MP:0006387]| abnormal T cell number [MP:0008495]| decreased IgG1 level [MP:0008496]| decreased IgG2a level [MP:0008502]| increased IgG3 level [MP:0008560]| increased tumor necrosis factor secretion [MP:0008566]| increased interferon-gamma secretion [MP:0008688]| decreased interleukin-2 secretion [MP:0009023] | Cd80 | 010623-UNC | Targeted Mutation | Mutant Mouse Resource and Research Center (MMRRC) | MMRRC | PMID:9075931 | MMRRC_10623-UNC, MMRRC_010623, MMRRC_1623 | 2026-09-12 06:42:28 | 0 | |||
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B6.129-Sgcbtm1Kcam/Mmmh Resource Report Resource Website |
RRID:MMRRC_010773-MU | Mus musculus | Research areas: Cardiovascular, Developmental Biology, Models for Human Disease, Neurobiology; Mutation Type: Targeted Mutation ; Collection: | dystrophic muscle [MP:0000752]| abnormal blood vessel morphology [MP:0001614]| abnormal muscle morphology [MP:0002108]| muscular atrophy [MP:0002269]| cardiac fibrosis [MP:0003141]| calcified muscle [MP:0003199]| aneurysm [MP:0003279]| abnormal sarcolemma morphology [MP:0004121]| cardiomyopathy [MP:0005330]| vascular stenosis [MP:0005412]| abnormal vascular smooth muscle morphology [MP:0005592]| myocardial necrosis [MP:0006085] | Sgcb | 010773-MU | Targeted Mutation | Mutant Mouse Resource and Research Center (MMRRC) | MMRRC | PMID:10678176 | MMRRC_10773-MU, MMRRC_010773, MMRRC_1773 | 2026-09-12 06:42:30 | 0 | |||
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B6.Cg-Get3tm1Hbha/Mmnc Resource Report Resource Website |
RRID:MMRRC_010859-UNC | Mus musculus | Research areas: Developmental Biology, Neurobiology, Research Tools; Mutation Type: Targeted Mutation ; Collection: | embryonic lethality [MP:0011092] | Get3 | 010859-UNC | Targeted Mutation | Mutant Mouse Resource and Research Center (MMRRC) | MMRRC | PMID:11470536 PMID:14651920 PMID:9712828 |
MMRRC_10859-UNC, MMRRC_010859, MMRRC_1859 | 2026-09-12 06:42:32 | 0 | |||
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C.129S4-Cd80tm1Shr/Mmmh Resource Report Resource Website |
RRID:MMRRC_011137-MU | Mus musculus | Research areas: Immunology and Inflammation; Mutation Type: Targeted Mutation ; Collection: | decreased cell proliferation [MP:0000352]| abnormal spleen morphology [MP:0000689]| decreased IgG level [MP:0001805]| brain inflammation [MP:0001847]| abnormal lymph node B cell domain morphology [MP:0002344]| abnormal T cell physiology [MP:0002444]| abnormal immunoglobulin level [MP:0002490]| increased IgM level [MP:0002494]| abnormal cytokine secretion [MP:0003009]| insulitis [MP:0004031]| increased susceptibility to experimental autoimmune encephalomyelitis [MP:0004799]| decreased susceptibility to experimental autoimmune encephalomyelitis [MP:0004800]| increased susceptibility to autoimmune diabetes [MP:0004803]| decreased susceptibility to autoimmune diabetes [MP:0004804]| decreased regulatory T cell number [MP:0004974]| decreased double-positive T cell number [MP:0005092]| decreased B cell proliferation [MP:0005093]| abnormal T cell proliferation [MP:0005094]| decreased T cell proliferation [MP:0005095]| increased T cell proliferation [MP:0005348]| abnormal CD4-positive [MP:0005463]| alpha-beta T cell physiology [MP:0005623]| abnormal meninges morphology [MP:0006387]| abnormal T cell number [MP:0008495]| decreased IgG1 level [MP:0008496]| decreased IgG2a level [MP:0008502]| increased IgG3 level [MP:0008560]| increased tumor necrosis factor secretion [MP:0008566]| increased interferon-gamma secretion [MP:0008688]| decreased interleukin-2 secretion [MP:0009023] | Cd80 | 011137-MU | Targeted Mutation | Mutant Mouse Resource and Research Center (MMRRC) | MMRRC | PMID:9075931 | MMRRC_11137-MU, MMRRC_011137, MMRRC_11137 | 2026-09-12 06:42:35 | 0 | |||
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B6.129S4-Tnfsf4tm1Shr/Mmmh Resource Report Resource Website |
RRID:MMRRC_011140-MU | Mus musculus | Research areas: Immunology and Inflammation; Mutation Type: Targeted Mutation ; Collection: | abnormal cell-mediated immunity [MP:0002421]| abnormal dendritic cell antigen presentation [MP:0002455]| abnormal cytokine secretion [MP:0003009]| decreased susceptibility to autoimmune diabetes [MP:0004804]| decreased T cell proliferation [MP:0005095]| decreased susceptibility to type IV hypersensitivity reaction [MP:0005616]| decreased interferon-gamma secretion [MP:0008567]| decreased interleukin-2 secretion [MP:0008688]| decreased interleukin-4 secretion [MP:0008700] | Tnfsf4 | 011140-MU | Targeted Mutation | Mutant Mouse Resource and Research Center (MMRRC) | MMRRC | PMID:10626891 | MMRRC_11140-MU, MMRRC_011140, MMRRC_1114 | 2026-09-12 06:42:35 | 0 | |||
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C.129S4-Cd80tm1Shr Cd86tm1Shr/Mmmh Resource Report Resource Website |
RRID:MMRRC_011139-MU | Mus musculus | Research areas: Immunology and Inflammation; Mutation Type: Targeted Mutation ; Collection: | decreased cell proliferation [MP:0000352]| abnormal spleen morphology [MP:0000689]| decreased IgG level [MP:0001805]| brain inflammation [MP:0001847]| abnormal lymph node B cell domain morphology [MP:0002344]| abnormal T cell physiology [MP:0002444]| abnormal immunoglobulin level [MP:0002490]| increased IgM level [MP:0002494]| abnormal cytokine secretion [MP:0003009]| insulitis [MP:0004031]| increased susceptibility to experimental autoimmune encephalomyelitis [MP:0004799]| decreased susceptibility to experimental autoimmune encephalomyelitis [MP:0004800]| increased susceptibility to autoimmune diabetes [MP:0004803]| decreased susceptibility to autoimmune diabetes [MP:0004804]| decreased regulatory T cell number [MP:0004974]| decreased double-positive T cell number [MP:0005092]| decreased B cell proliferation [MP:0005093]| abnormal T cell proliferation [MP:0005094]| decreased T cell proliferation [MP:0005095]| increased T cell proliferation [MP:0005348]| abnormal CD4-positive [MP:0005463]| alpha-beta T cell physiology [MP:0005623]| abnormal meninges morphology [MP:0006387]| abnormal T cell number [MP:0008495]| decreased IgG1 level [MP:0008496]| decreased IgG2a level [MP:0008502]| increased IgG3 level [MP:0008560]| increased tumor necrosis factor secretion [MP:0008566]| increased interferon-gamma secretion [MP:0008688]| decreased interleukin-2 secretion [MP:0009023]| paresis [MP:0000754]| hindlimb paralysis [MP:0000755]| demyelination [MP:0000921]| abnormal dorsal root ganglion morphology [MP:0000961]| abnormal humoral immune response [MP:0001800]| decreased IgG level [MP:0001805]| brain inflammation [MP:0001847]| muscular atrophy [MP:0002269]| abnormal nervous system morphology [MP:0003632]| increased autoantibody level [MP:0003725]| abnormal myelin sheath morphology [MP:0003871]| abnormal ventral spinal root morphology [MP:0003993]| abnormal dorsal spinal root morphology [MP:0003994]| decreased susceptibility to experimental autoimmune encephalomyelitis [MP:0004800]| increased susceptibility to autoimmune diabetes [MP:0004803]| decreased susceptibility to autoimmune diabetes [MP:0004804]| decreased regulatory T cell number [MP:0004974]| abnormal T cell proliferation [MP:0005094]| decreased T cell proliferation [MP:0005095]| abnormal action potential [MP:0005402]| abnormal nerve conduction [MP:0005403]| absent spleen germinal center [MP:0008474]| increased tumor necrosis factor secretion [MP:0008560]| decreased tumor necrosis factor secretion [MP:0008561]| increased interferon-gamma secretion [MP:0008566]| decreased interleukin-12 secretion [MP:0008664]| decreased nerve conduction velocity [MP:0008814]| decreased grip strength [MP:0010053] | ||Cd80|Cd86 | 011139-MU | Targeted Mutation | Mutant Mouse Resource and Research Center (MMRRC) | MMRRC | PMID:9075931 | MMRRC_11139-MU, MMRRC_011139, MMRRC_11139 | 2026-09-12 06:42:35 | 0 | |||
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STOCK Nos2tm1Mrl Tg(APPSWE)2576Kha Tg(Thy1-PSEN1*A246E)16-3Sqn/Mmnc Resource Report Resource Website |
RRID:MMRRC_011171-UNC | Mus musculus | Research areas: Immunology and Inflammation, Models for Human Disease, Neurobiology; Mutation Type: Targeted Mutation ; Collection: | increased white adipose tissue amount [MP:0000008]| increased bone mineral density [MP:0000062]| abnormal trabecular bone morphology [MP:0000130]| increased circulating LDL cholesterol level [MP:0000182]| abnormal circulating glucose level [MP:0000188]| abnormal circulating serum albumin level [MP:0000199]| hypertension [MP:0000231]| decreased digestive secretion [MP:0000505]| abnormal uterus morphology [MP:0001120]| increased body weight [MP:0001260]| polydipsia [MP:0001426]| dehydration [MP:0001429]| abnormal skeleton physiology [MP:0001533]| abnormal osteoclast physiology [MP:0001541]| abnormal cardiovascular system physiology [MP:0001544]| increased circulating triglyceride level [MP:0001552]| irregular heartbeat [MP:0001636]| abnormal digestion [MP:0001664]| polyuria [MP:0001762]| abnormal homeostasis [MP:0001764]| abnormal immune system physiology [MP:0001790]| decreased IgG level [MP:0001805]| decreased IgM level [MP:0001806]| increased inflammatory response [MP:0001846]| pancreas inflammation [MP:0001869]| abnormal mammary gland physiology [MP:0001881]| reduced fertility [MP:0001921]| decreased litter size [MP:0001935]| abnormal motor capabilities/coordination/movement [MP:0002066]| abnormal sensory capabilities/reflexes/nociception [MP:0002067]| abnormal glucose homeostasis [MP:0002078]| premature death [MP:0002083]| abnormal cardiovascular system morphology [MP:0002127]| abnormal blood circulation [MP:0002128]| abnormal kidney physiology [MP:0002136]| increased susceptibility to bacterial infection [MP:0002412]| abnormal macrophage physiology [MP:0002451]| abnormal immunoglobulin level [MP:0002490]| abnormal eosinophil cell number [MP:0002602]| abnormal vitreous body morphology [MP:0002699]| abnormal thermal nociception [MP:0002733]| increased systemic arterial blood pressure [MP:0002842]| increased growth rate [MP:0002865]| increased insulin sensitivity [MP:0002891]| abnormal bone mineralization [MP:0002896]| delayed wound healing [MP:0002908]| thick ventricular wall [MP:0002953]| increased circulating alkaline phosphatase level [MP:0002968]| abnormal cardiac muscle contractility [MP:0002972]| decreased urine osmolality [MP:0002988]| abnormal bone healing [MP:0002999]| increased myocardial infarction size [MP:0003037]| allodynia [MP:0003177]| neuron degeneration [MP:0003224]| liver fibrosis [MP:0003333]| abnormal bone structure [MP:0003795]| enlarged stomach [MP:0003883]| abnormal tooth hard tissue morphology [MP:0003930]| abnormal hormone level [MP:0003953]| abnormal nitric oxide homeostasis [MP:0003957]| abnormal adrenocorticotropin level [MP:0003966]| decreased cholesterol level [MP:0003983]| arteriosclerosis [MP:0003991]| abnormal uterine artery morphology [MP:0003995]| abnormal vascular endothelial cell physiology [MP:0004003]| decreased susceptibility to kidney reperfusion injury [MP:0004042]| abnormal coronary artery morphology [MP:0004111]| increased renal tubule apoptosis [MP:0004153]| renal tubular necrosis [MP:0004154]| abnormal myocardial fiber physiology [MP:0004215]| abnormal peripheral nervous system regeneration [MP:0004220]| increased length of allograft survival [MP:0004751]| increased susceptibility to experimental autoimmune encephalomyelitis [MP:0004799]| increased mean systemic arterial blood pressure [MP:0004875]| abnormal vascular wound healing [MP:0004883]| decreased adiponectin level [MP:0004893]| abnormal osteoclast morphology [MP:0004982]| increased osteoclast cell number [MP:0004984]| decreased osteoclast cell number [MP:0004985]| decreased eosinophil cell number [MP:0005012]| abnormal response to infection [MP:0005025]| increased circulating prolactin level [MP:0005124]| decreased cardiac muscle contractility [MP:0005140]| increased circulating cholesterol level [MP:0005178]| abnormal circulating estradiol level [MP:0005183]| glomerulosclerosis [MP:0005264]| improved glucose tolerance [MP:0005292]| abnormal heart ventricle morphology [MP:0005294]| abnormal response to tactile stimuli [MP:0005316]| abnormal renal glomerulus morphology [MP:0005325]| decreased heart rate [MP:0005333]| atherosclerotic lesions [MP:0005338]| increased circulating creatinine level [MP:0005553]| increased blood urea nitrogen level [MP:0005565]| increased renin activity [MP:0005582]| decreased cerebral infarction size [MP:0006058]| congestive heart failure [MP:0006138]| abnormal atrioventricular node conduction [MP:0006141]| increased systemic arterial systolic blood pressure [MP:0006144]| abnormal involution of the mammary gland [MP:0006271]| decreased urine sodium level [MP:0006317]| intestine polyps [MP:0008011]| abnormal osteoclast differentiation [MP:0008396]| increased IgG2a level [MP:0008500]| increased interferon-gamma secretion [MP:0008566]| decreased susceptibility to endotoxin shock [MP:0008734]| decreased survivor rate [MP:0008770]| abnormal heart ventricle pressure [MP:0008775]| increased blood osmolality [MP:0008997]| prolonged diestrus [MP:0009011]| abnormal platelet aggregation [MP:0009548]| abnormal blood homeostasis [MP:0009642]| abnormal urine homeostasis [MP:0009643]| abnormal induced retinal neovascularization [MP:0009660]| increased prostaglandin level [MP:0009814]| visceral vascular congestion [MP:0010017]| pulmonary vascular congestion [MP:0010018]| liver vascular congestion [MP:0010019]| abnormal heart electrocardiography waveform feature [MP:0010508]| abnormal heart right ventricle pressure [MP:0010755]| pyloric sphincter hypertrophy [MP:0010781]| increased bone volume [MP:0010875]| increased compact bone mass [MP:0010961]| glomerular capillary thrombosis [MP:0011508]| decreased urine prostaglandin level [MP:0011564]| decreased urine nitrite level [MP:0011742]| perivascular fibrosis [MP:0011749]| increased food intake [MP:0011939]| hyperlactation [MP:0013717]| increased circulating LDL cholesterol level [MP:0000182]| amyloidosis [MP:0000604]| abnormal forebrain morphology [MP:0000783]| abnormal hindbrain morphology [MP:0000841]| small cerebellum [MP:0000852]| abnormal cerebellar foliation [MP:0000857]| decreased body weight [MP:0001262]| decreased anxiety-related response [MP:0001364]| hyperactivity [MP:0001399]| abnormal response to new environment [MP:0001413]| decreased exploration in new environment [MP:0001417]| decreased grooming behavior [MP:0001442]| abnormal object recognition memory [MP:0001458]| abnormal spatial learning [MP:0001463]| reduced long term potentiation [MP:0001473]| hunched posture [MP:0001505]| abnormal lipid level [MP:0001547]| impaired synaptic plasticity [MP:0001900]| reduced NMDA-mediated synaptic currents [MP:0001902]| intracranial hemorrhage [MP:0001915]| postnatal lethality [MP:0002082]| premature death [MP:0002083]| abnormal blood circulation [MP:0002128]| abnormal astrocyte morphology [MP:0002182]| gliosis [MP:0002183]| neurodegeneration [MP:0002229]| increased thigmotaxis [MP:0002797]| abnormal eye blink conditioning behavior [MP:0002807]| abnormal neuron morphology [MP:0002882]| abnormal excitatory postsynaptic potential [MP:0002912]| decreased post-tetanic potentiation [MP:0002922]| neurofibrillary tangles [MP:0003214]| neuron degeneration [MP:0003224]| loss of hippocampal neurons [MP:0003240]| amyloid beta deposits [MP:0003329]| astrocytosis [MP:0003354]| abnormal microglial cell physiology [MP:0003691]| tau protein deposits [MP:0004250]| cerebral amyloid angiopathy [MP:0004254]| abnormal miniature excitatory postsynaptic currents [MP:0004753]| abnormal neuron physiology [MP:0004811]| increased circulating cholesterol level [MP:0005178]| abnormal eye physiology [MP:0005253]| abnormal renal glomerulus morphology [MP:0005325]| abnormal hippocampus CA3 region morphology [MP:0008267]| abnormal subiculum morphology [MP:0008287]| abnormal spatial working memory [MP:0008428]| abnormal short term spatial reference memory [MP:0008431]| abnormal long term spatial reference memory [MP:0008432]| microgliosis [MP:0008918]| decreased neuron number [MP:0008948]| paraparesis [MP:0009434]| enhanced contextual conditioning behavior [MP:0009453]| abnormal synapse morphology [MP:0009538]| decreased brain zinc level [MP:0009617]| increased brain zinc level [MP:0009618]| reduced AMPA-mediated synaptic currents [MP:0011003]| abnormal catecholamine level [MP:0011479]| decreased vocalization [MP:0020351] | |Nos2|APP||Prnp|PSEN1|THY1| | 011171-UNC | Targeted Mutation | Mutant Mouse Resource and Research Center (MMRRC) | MMRRC | PMID:16260491 PMID:8810256 PMID:7538909 PMID:15450355 PMID:9539133 PMID:1302033 PMID:7576662 |
MMRRC_11171-UNC, MMRRC_011171, MMRRC_11171 | 2026-09-12 06:42:35 | 0 | |||
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B6;129-Kif3ctm2Gsn/Mmucd Resource Report Resource Website |
RRID:MMRRC_000215-UCD | Mus musculus | Research areas: Cell Biology, Models for Human Disease, Neurobiology, Sensorineural; Mutation Type: Targeted Mutation ; Collection: | no abnormal phenotype detected [MP:0002169] | Kif3c | 000215-UCD | Targeted Mutation | Mutant Mouse Resource and Research Center (MMRRC) | MMRRC | PMID:11463814 | MMRRC_215-UCD, MMRRC_000215, MMRRC_215 | 2026-09-12 06:39:33 | 0 | |||
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B6.129S7-Chrnb2tm1Mdb/Mmnc Resource Report Resource Website 1+ mentions |
RRID:MMRRC_000211-UNC | Mus musculus | Research areas: Models for Human Disease, Neurobiology; Mutation Type: Targeted Mutation ; Collection: | delayed ear emergence [MP:0000054]| delayed hair appearance [MP:0000422]| distended urinary bladder [MP:0000539]| abnormal urinary bladder urothelium morphology [MP:0000540]| decreased anxiety-related response [MP:0001364]| hyperactivity [MP:0001399]| postnatal growth retardation [MP:0001732]| no abnormal phenotype detected [MP:0002169]| increased susceptibility to bacterial infection [MP:0002412]| mydriasis [MP:0002546]| urinary incontinence [MP:0003280]| intestinal hypoperistalsis [MP:0003290]| abnormal single cell response [MP:0003463]| enhanced coordination [MP:0003858]| impaired passive avoidance behavior [MP:0004000]| abnormal lateral geniculate nucleus morphology [MP:0004165]| eyelids fail to open [MP:0005176]| narrow eye opening [MP:0005287]| abnormal eye electrophysiology [MP:0005551]| impaired pupillary reflex [MP:0006243]| abnormal autonomic nervous system physiology [MP:0006276]| urinary bladder inflammation [MP:0009646]| abnormal urinary bladder physiology [MP:0010386]| postnatal lethality [MP:0011085]| complete penetrance [MP:0011625] | Chrnb2 | 000211-UNC | Targeted Mutation | Mutant Mouse Resource and Research Center (MMRRC) | MMRRC | PMID:10531434 PMID:10235262 PMID:9428762 |
MMRRC_211-UNC, MMRRC_000211, MMRRC_211 | 2026-09-12 06:39:33 | 1 | |||
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B6;129X1-Prkacatm1Gsm/Mmnc Resource Report Resource Website 1+ mentions |
RRID:MMRRC_000199-UNC | Mus musculus | Research areas: Apoptosis, Cardiovascular, Cell Biology, Developmental Biology, Diabetes, Endocrine Deficiency, Immunology and Inflammation, Metabolism, Neurobiology, Reproduction; Mutation Type: Targeted Mutation ; Collection: | decreased bone mineral density [MP:0000063]| exencephaly [MP:0000914]| abnormal dorsal root ganglion morphology [MP:0000961]| disorganized dorsal root ganglion [MP:0000962]| decreased body weight [MP:0001262]| postnatal growth retardation [MP:0001732]| pericardial edema [MP:0001787]| male infertility [MP:0001925]| postnatal lethality [MP:0002082]| abnormal skeleton development [MP:0002113]| abnormal neural tube morphology [MP:0002151]| asthenozoospermia [MP:0002675]| abnormal bone mineralization [MP:0002896]| abnormal neuron specification [MP:0002948]| decreased urine protein level [MP:0002963]| spina bifida [MP:0003054]| increased osteosarcoma incidence [MP:0003789]| abnormal compact bone morphology [MP:0003797]| abnormal spine curvature [MP:0004174]| abnormal embryonic neuroepithelium morphology [MP:0004261]| abnormal vertebral arch morphology [MP:0004599]| abnormal vertebral column morphology [MP:0004703]| decreased trabecular bone thickness [MP:0009346]| increased osteochondroma incidence [MP:0010079]| increased skeletal tumor incidence [MP:0010280]| abnormal periosteum morphology [MP:0010971]| postnatal lethality [MP:0011086]| incomplete penetrance [MP:0011092]| embryonic lethality [MP:0011097]| complete penetrance [MP:0012505] | Prkaca | 000199-UNC | Targeted Mutation | Mutant Mouse Resource and Research Center (MMRRC) | MMRRC | PMID:11875122 | MMRRC_199-UNC, MMRRC_000199, MMRRC_199 | 2026-09-12 06:39:32 | 1 | |||
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B6.Cg-Sod1tm1Cje/Mmmh Resource Report Resource Website |
RRID:MMRRC_000203-MU | Mus musculus | Research areas: Apoptosis, Cancer, Cell Biology, Diabetes, Models for Human Disease; Mutation Type: Targeted Mutation ; Collection: | decreased fibroblast proliferation [MP:0011704] increased fibroblast apoptosis [MP:0013501] | Sod1 | 000203-MU | Targeted Mutation | Mutant Mouse Resource and Research Center (MMRRC) | MMRRC | PMID:9264557 PMID:9151735 PMID:9416279 |
MMRRC_203-MU, MMRRC_000203, MMRRC_23 | 2026-09-12 06:39:33 | 0 | |||
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FVB.129S2-Plntm1Egk/Mmmh Resource Report Resource Website |
RRID:MMRRC_000228-MU | Mus musculus | Research areas: ; Mutation Type: Targeted Mutation ; Collection: | abnormal heart shape [MP:0000277]| abnormal interventricular septum morphology [MP:0000281]| abnormal eye development [MP:0001286]| cardiac hypertrophy [MP:0001625]| abnormal cardiac output [MP:0001627]| premature death [MP:0002083]| dilated heart left ventricle [MP:0002753]| dilated cardiomyopathy [MP:0002795]| increased heart weight [MP:0002833]| thick ventricular wall [MP:0002953]| abnormal cardiac muscle contractility [MP:0002972]| abnormal locomotor activation [MP:0003313]| abnormal cardiac muscle relaxation [MP:0004084]| abnormal myocardial fiber physiology [MP:0004215]| abnormal calcium ion homeostasis [MP:0004231]| enlarged myocardial fiber [MP:0004564]| decreased cardiac muscle contractility [MP:0005140]| decreased heart rate [MP:0005333]| increased cardiac muscle contractility [MP:0005599]| congestive heart failure [MP:0006138]| atrial fibrillation [MP:0008543]| increased heart left ventricle size [MP:0010579]| abnormal heart left ventricle pressure [MP:0010754]| neonatal lethality [MP:0011087]| complete penetrance [MP:0011952]| decreased cardiac stroke volume [MP:0020346] | Pln | 000228-MU | Targeted Mutation | Mutant Mouse Resource and Research Center (MMRRC) | MMRRC | PMID:12504816 | MMRRC_228-MU, MMRRC_000228, MMRRC_228 | 2026-09-12 06:39:33 | 0 | |||
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B6.129S6-Il4tm1Rao/Mmnc Resource Report Resource Website |
RRID:MMRRC_000227-UNC | Mus musculus | Research areas: Cell Biology, Immunology and Inflammation, Models for Human Disease; Mutation Type: Targeted Mutation ; Collection: | abnormal mast cell physiology [MP:0002423]| abnormal T-helper 2 physiology [MP:0005466]| decreased interleukin-13 secretion [MP:0008673]| decreased interleukin-4 secretion [MP:0008700] | Il4 | 000227-UNC | Targeted Mutation | Mutant Mouse Resource and Research Center (MMRRC) | MMRRC | PMID:12150890 | MMRRC_227-UNC, MMRRC_000227, MMRRC_227 | 2026-09-12 06:39:33 | 0 |
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