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Integrated Animals is a virtual database currently indexing available animal strains and mutants from: AGSC (Ambystoma), BCBC (mice), BDSC (flies), European Xenopus Resource Center (frog), The National Xenopus Resource (frog), Xenopus Express (frog), CWRU Cystic Fibrosis Mouse Models (mice), DGGR (flies), FlyBase (flies), IMSR (mice), MGI (mice), MMRRC (mice), NSRRC (pig), RGD (rats), Sperm Stem Cell Libraries for Biological Research (rats), Tetrahymena Stock Center (Tetrahymena), WormBase (worms), XGSC (Xiphophorus), ZFIN (zebrafish), and ZIRC (zebrafish). Note, the IMSR data is linked, but users may need to re-execute the search if the top mouse is not returned properly.
Note: BCBC is no longer in service, so the links may not be functional.
https://www.mmrrc.org/catalog/sds.php?mmrrc_id=43958
Source Database: Mutant Mouse Resource and Research Center (MMRRC)
Genetic Background: Transgenic
Affected Genes: Cfh|Rpl10a|EGFP|
Source References: PMID: 24810037
Alternate IDs: MMRRC_43958-MU, MMRRC_043958, MMRRC_43958
Notes: Research areas: Neurobiology; Mutation Type: Transgenic ; Collection:
Proper citation: RRID:MMRRC_043958-MU Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=1566458
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: transgenic
Availability: Cryopreserved Sperm (as of 2019-07-01)
Alternate IDs: RGD_1566458, 1566458, RRRC_48, RRRC_048, RRRC_0048, RRRC_00048
Notes: F344 embryos were microinjected with R26-hPAP trangene which comprises of 0.8 kb genomic sequence of ROSA 26 promoter fused to human placental alkaline phosphatase (hPAP, ALPP). Rat Resource and Research Center
Proper citation: RRID:RRRC_00048 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=737703
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: transgenic
Availability: Cryopreserved Embryo; Cryopreserved Sperm (as of 2020-07-08)
Alternate IDs: RGD_737703, 737703, RRRC_42, RRRC_042, RRRC_0042, RRRC_00042
Notes: Lewis from CRL were used as the background strain. This strain was made by pronuclear injection into Lewis embryos. The embryos were coinjected with DNA fragments containing the HLA-B*0702 human gene and the human beta-2-microglobulin gene. Founder 120-4 was selected and carrier animals from this founder were mated and this strain was bred to homozygosity. Rat Resource and Research Center
Proper citation: RRID:RRRC_00042 Copy
http://rgd.mcw.edu/tools/strains/strains_view.cgi?id=1300439
Source Database: Rat Resource and Research Center (RRRC)
Genetic Background: transgenic
Availability: Live Animals; Cryopreserved Embryo; Cryopreserved Sperm (as of 2017-07-10)
Alternate IDs: RGD_1300439, 1300439, RRRC_65, RRRC_065, RRRC_0065, RRRC_00065
Notes: This transgenic strain contains the enhanced green fluorescent protein gene under the control of the human ubiquitin-C promoter with a the woodchuck hepatitis virus posttranscriptional regulatory element (WRE). This transgenic strain was made by injecting the lentivirus vector containing the GFP construct (vector name FUGW) into SD rat embryos. Animals that exhibited fluorescence of tails where then mated. The colony was transferred from Carlos Lois, California Institute of Technology, Pasedena, California to the Rat Resource and Research Center in 2002. This strain has been maintained by backcrossing carrier males to SD stock females in order to segregate transgenes and maintain the SD background. The strain now carries a single transgene which is located at chromosome 14q21. Rat Resource and Research Center
Proper citation: RRID:RRRC_00065 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=629501
Source Database: Rat Genome Database (RGD)
Genetic Background: transgenic
Availability: Unknown
Alternate IDs: 629501
Notes: This is a hypertensive rat strain in which the mouse Ren2 renin gene along with its 5' and 3' flanking sequences were microinjected into fertilized eggs from a Hannover Sprague-Dawley (SD) background.
Proper citation: RRID:RGD_629501 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=152977768
Source Database: Rat Genome Database (RGD)
Genetic Background: transgenic
Availability: Unknown
Alternate IDs: 152977768
Notes: The KOR-Venus construct consisting of promoter of rat Oprk1 (opioid receptor, kappa 1) fused with Venus fluorescent protein, was introduced into fertilized eggs of Wistar rats (Crlj:WI, Charles River Japan). They were then crossed with Wistar-Imamichi rats (Iar:Wistar-Imamichi, Institute for Animal Reproduction) to maintain the strain. Transgenic rats expressing the fluorescent protein Venus under the control of the Oprk1 promoter. This strain is heterozygous. National BioResource Project for the Rat in Japan
Proper citation: RRID:RGD_152977768 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=1358305
Source Database: Rat Genome Database (RGD)
Genetic Background: transgenic
Availability: Unknown
Alternate IDs: 1358305
Notes: This transgenic strain carries a mouse rhodopsin gene that bears a termination codon at residue 334, which encodes a C-terminal truncated opsin protein. Retinal Degeneration Rat Model Resource
Proper citation: RRID:RGD_1358305 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=1358306
Source Database: Rat Genome Database (RGD)
Genetic Background: transgenic
Availability: Unknown
Alternate IDs: 1358306
Notes: This transgenic strain carries a mouse rhodopsin gene that bears a termination codon at residue 334, which encodes a C-terminal truncated opsin protein. Retinal Degeneration Rat Model Resource
Proper citation: RRID:RGD_1358306 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=1358304
Source Database: Rat Genome Database (RGD)
Genetic Background: transgenic
Availability: Unknown
Alternate IDs: 1358304
Notes: This transgenic strain carries a mouse rhodopsin gene that bears a termination codon at residue 334, which encodes a C-terminal truncated opsin protein. Retinal Degeneration Rat Model Resource
Proper citation: RRID:RGD_1358304 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=1357417
Source Database: Rat Genome Database (RGD)
Genetic Background: transgenic
Availability: Unknown
Alternate IDs: 1357417
Notes: 14.5 kb lambda clone of the rat Npy gene was subcloned with a polylinker that had NotI and EcoRI restriction sites. This transgene that was released by NotI digestion contained ~5kb 5'and ~1kb 3' and was injected into the pronuclei of fertilized SD rats. Founders were mated with SD females. F1 animals were mated with SD females till line 400 hemizygous animals were developed that had 5 copies of the Npy gene.
Proper citation: RRID:RGD_1357417 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=1357182
Source Database: Rat Genome Database (RGD)
Genetic Background: transgenic
Availability: Unknown
Alternate IDs: 1357182
Notes: Wild type Tsc2 transgene was constructed from the Tsc2 cDNA from BN rat and was microinjected into single male pronuclei. Eggs were cultured and tranferred into female wistar which were mated with Eker rats.
Proper citation: RRID:RGD_1357182 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=1559030
Source Database: Rat Genome Database (RGD)
Genetic Background: transgenic
Availability: Cryopreserved Embryo; Cryopreserved Sperm
Alternate IDs: 1559030
Notes: A 4.5 kb fragment of human ATP7B cDNA was blunt-end ligated into the pCXN2 vector that contained the CAG promoter to generate pCXN2ATP7B which was microinjected into the pronuclei of LEC/Crlj. The transgenic founders were identified by the PCR analysis of the tail-DNA. National BioResource Project for the Rat in Japan
Proper citation: RRID:RGD_1559030 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=1554305
Source Database: Rat Genome Database (RGD)
Genetic Background: transgenic
Availability: Cryopreserved Embryo
Alternate IDs: 1554305
Notes: lacZ cDNA was inserted in the EcoRI site of the pCAGGS expression vector. This DNA was microinjected into the DA/Crlj. The expression of the transgene was determined by beta-gal staining. National BioResource Project for the Rat in Japan
Proper citation: RRID:RGD_1554305 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=1642994
Source Database: Rat Genome Database (RGD)
Genetic Background: transgenic
Availability: Unknown
Alternate IDs: 1642994
Notes: This transgenic strain contains the enhanced green fluorescent protein gene drived by ubiquitous CAG promoter. This vector contains long terminal repeats with self-inactivating mutation, a central polypurine tract of HIV-1, a human cytomegalovirus and a composite intron from rabbit beta-globin. This transgenic strain was made by injecting the lentivirus vector containing the eGFP construct (lentiviral-CAG-eGFP) into SS rat embryos.
Proper citation: RRID:RGD_1642994 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=1642995
Source Database: Rat Genome Database (RGD)
Genetic Background: transgenic
Availability: Unknown
Alternate IDs: 1642995
Notes: This transgenic strain contains the enhanced green fluorescent protein gene drived by ubiquitous CAG promoter. This vector contains long terminal repeats with self-inactivating mutation, a central polypurine tract of HIV-1, a human cytomegalovirus and a composite intron from rabbit beta-globin. This transgenic strain was made by injecting the lentivirus vector containing the eGFP construct (lentiviral-CAG-eGFP) into SS rat embryos.
Proper citation: RRID:RGD_1642995 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=1642992
Source Database: Rat Genome Database (RGD)
Genetic Background: transgenic
Availability: Unknown
Alternate IDs: 1642992
Notes: This transgenic strain contains the enhanced green fluorescent protein gene drived by ubiquitous CAG promoter. This vector contains long terminal repeats with self-inactivating mutation, a central polypurine tract of HIV-1, a human cytomegalovirus and a composite intron from rabbit beta-globin. This transgenic strain was made by injecting the lentivirus vector containing the eGFP construct (lentiviral-CAG-eGFP) into SS rat embryos.
Proper citation: RRID:RGD_1642992 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=1642993
Source Database: Rat Genome Database (RGD)
Genetic Background: transgenic
Availability: Unknown
Alternate IDs: 1642993
Notes: This transgenic strain contains the enhanced green fluorescent protein gene drived by ubiquitous CAG promoter. This vector contains long terminal repeats with self-inactivating mutation, a central polypurine tract of HIV-1, a human cytomegalovirus and a composite intron from rabbit beta-globin. This transgenic strain was made by injecting the lentivirus vector containing the eGFP construct (lentiviral-CAG-eGFP) into SD rat embryos.
Proper citation: RRID:RGD_1642993 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=1642989
Source Database: Rat Genome Database (RGD)
Genetic Background: transgenic
Availability: Cryopreserved Sperm (as of 2019-04-04)
Alternate IDs: 1642989
Notes: This transgenic strain contains the enhanced green fluorescent protein gene drived by ubiquitous CAG promoter. This vector contains long terminal repeats with self-inactivating mutation, a central polypurine tract of HIV-1, a human cytomegalovirus and a composite intron from rabbit beta-globin. This transgenic strain was made by injecting the lentivirus vector containing the eGFP construct (lentiviral-CAG-eGFP) into SS rat embryos.
Proper citation: RRID:RGD_1642989 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=2290057
Source Database: Rat Genome Database (RGD)
Genetic Background: transgenic
Availability: Cryopreserved Sperm
Alternate IDs: 2290057
Notes: The Sleeping Beauty transposon construct, T2/Bart3 consists of inverted terminal repeats separated by a gene trap cassette. The gene trap cassette consists of two splice acceptors, one from adenovirus and one from the mouse Hox9a gene, situated in opposite orientations. Each splice acceptor is followed by stop codons in each reading frame and a polyadenylation signal. Furthermore, the T2/Bart3 transposon harbors a mouse tyrosinase minigene which rescues the phenotype of albino rats, but demonstrates position effect variegated expression.
Proper citation: RRID:RGD_2290057 Copy
https://rgd.mcw.edu/rgdweb/report/strain/main.html?id=1642990
Source Database: Rat Genome Database (RGD)
Genetic Background: transgenic
Availability: Unknown
Alternate IDs: 1642990
Notes: This transgenic strain contains the enhanced green fluorescent protein gene drived by ubiquitous CAG promoter. This vector contains long terminal repeats with self-inactivating mutation, a central polypurine tract of HIV-1, a human cytomegalovirus and a composite intron from rabbit beta-globin. This transgenic strain was made by injecting the lentivirus vector containing the eGFP construct (lentiviral-CAG-eGFP) into SD rat embryos.
Proper citation: RRID:RGD_1642990 Copy
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