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Integrated Animals is a virtual database currently indexing available animal strains and mutants from: AGSC (Ambystoma), BCBC (mice), BDSC (flies), European Xenopus Resource Center (frog), The National Xenopus Resource (frog), Xenopus Express (frog), CWRU Cystic Fibrosis Mouse Models (mice), DGGR (flies), FlyBase (flies), IMSR (mice), MGI (mice), MMRRC (mice), NSRRC (pig), RGD (rats), Sperm Stem Cell Libraries for Biological Research (rats), Tetrahymena Stock Center (Tetrahymena), WormBase (worms), XGSC (Xiphophorus), ZFIN (zebrafish), and ZIRC (zebrafish). Note, the IMSR data is linked, but users may need to re-execute the search if the top mouse is not returned properly.
Note: BCBC is no longer in service, so the links may not be functional.
http://www.wormbase.org/db/get?name=WBStrain00023563
Source Database: WormBase (WB)
Affected Genes: WBGene00001072(dpy-10)|WBGene00006744(unc-4)|WBGene00006787(unc-52)|WBGene00010785(top-2)
Genomic Alteration: WBGene00001072(dpy-10), WBGene00006744(unc-4), WBGene00006787(unc-52), WBGene00010785(top-2)
Availability: available
Source References: PMID:3224814
Synonyms: unc-4(e120) top-2(it38)/mnC1 [dpy-10(e128) unc-52(e444)] II.
Alternate IDs: WB-STRAIN:KK352, CGC_KK352
Notes: Heterozygotes are WT and segregate WT, DpyUnc and Unc-4s which give only dead eggs. Maintain by picking WT. Not a strict maternal effect-rescued by male mating.
Proper citation: RRID:WB-STRAIN:WBStrain00023563 Copy
http://www.wormbase.org/db/get?name=WBStrain00023561
Source Database: WormBase (WB)
Affected Genes: WBGene00001072(dpy-10)|WBGene00003195(mel-10)|WBGene00005016(sqt-1)|WBGene00006744(unc-4)|WBGene00006787(unc-52)
Genomic Alteration: WBGene00001072(dpy-10), WBGene00003195(mel-10), WBGene00005016(sqt-1), WBGene00006744(unc-4), WBGene00006787(unc-52)
Availability: available
Source References: PMID:3224814
Synonyms: mel-10(it10) unc-4(e120) sqt-1(sc13)/mnC1 [dpy-10(e128) unc-52(e444)] II.
Alternate IDs: WB-STRAIN:KK338, CGC_KK338
Notes: Heterozygotes are WT and segregate WT, DpyUnc and Unc-4s which give only dead eggs. Maintain by picking WT. Strict maternal effect.
Proper citation: RRID:WB-STRAIN:WBStrain00023561 Copy
http://www.wormbase.org/db/get?name=WBStrain00023566
Source Database: WormBase (WB)
Affected Genes: WBGene00001072(dpy-10)|WBGene00006744(unc-4)|WBGene00006787(unc-52)|WBGene00017132(tofu-6)
Genomic Alteration: WBGene00001072(dpy-10), WBGene00006744(unc-4), WBGene00006787(unc-52), WBGene00017132(tofu-6)
Availability: available
Source References: PMID:3224814
Synonyms: tofu-6(it20) unc-4(e120)/mnC1 [dpy-10(e128) unc-52(e444)] II.
Alternate IDs: WB-STRAIN:KK359, CGC_KK359
Notes: Heterozygotes are WT and segregate WT, DpyUnc and Unc-4s which give only dead eggs. Maintain by picking WT. Strict maternal effect.
Proper citation: RRID:WB-STRAIN:WBStrain00023566 Copy
http://www.wormbase.org/db/get?name=WBStrain00023567
Source Database: WormBase (WB)
Affected Genes: WBGene00001072(dpy-10)|WBGene00003193(mel-8)|WBGene00006744(unc-4)|WBGene00006787(unc-52)
Genomic Alteration: WBGene00001072(dpy-10), WBGene00003193(mel-8), WBGene00006744(unc-4), WBGene00006787(unc-52)
Availability: available
Source References: PMID:3224814
Synonyms: mel-8(it27) unc-4(e120)/mnC1 [dpy-10(e128) unc-52(e444)] II.
Alternate IDs: WB-STRAIN:KK364, CGC_KK364
Notes: mel-8 is a maternal effect lethal. WT heterozygotes segregate WT; mel-8 unc-4 homozygotes that lay eggs that don't hatch, and mnC1 dpy-10 unc-52 homozygotes (paralyzed Dpys). Some F2 mel homozygotes hatch, but such escapers arrest at L1 or L2. Previously called mel-6(it27).
Proper citation: RRID:WB-STRAIN:WBStrain00023567 Copy
http://www.wormbase.org/db/get?name=WBStrain00023600
Source Database: WormBase (WB)
Affected Genes: WBGene00000871(cye-1)|WBGene00001075(dpy-14)
Genomic Alteration: WBGene00000871(cye-1), WBGene00001075(dpy-14)
Availability: available
Synonyms: cye-1(eh10)/dpy-14(e188) I.
Alternate IDs: WB-STRAIN:KM166, CGC_KM166
Notes: Heterozygotes are WT and segregate WT, Dpys, and Sterile Pvl.
Proper citation: RRID:WB-STRAIN:WBStrain00023600 Copy
http://www.wormbase.org/db/get?name=WBStrain00023564
Source Database: WormBase (WB)
Affected Genes: WBGene00001072(dpy-10)|WBGene00003190(mel-4)|WBGene00006744(unc-4)|WBGene00006787(unc-52)
Genomic Alteration: WBGene00001072(dpy-10), WBGene00003190(mel-4), WBGene00006744(unc-4), WBGene00006787(unc-52)
Availability: available
Source References: PMID:3224814
Synonyms: mel-4(it12) unc-4(e120)/mnC1 [dpy-10(e128) unc-52(e444)] II.
Alternate IDs: WB-STRAIN:KK356, CGC_KK356
Notes: Heterozygotes are WT and segregate WT, DpyUnc and Unc-4s which give only dead eggs (it12 is temperature sensitive). Maintain by picking WT. Strict maternal effect.
Proper citation: RRID:WB-STRAIN:WBStrain00023564 Copy
http://www.wormbase.org/db/get?name=WBStrain00023504
Source Database: WormBase (WB)
Affected Genes: WBGene00006513(rimb-1)
Genomic Alteration: WBGene00006513(rimb-1)
Availability: available
Synonyms: rimb-1(ce828) III.
Alternate IDs: WB-STRAIN:KG4995, CGC_KG4995
Notes: Superficially wild type on plates. Slight (<10%), but significant, expansion of synaptic vesicles from the synaptic region of the DA9 motor neuron into the flanking asynaptic regions. Synaptic vesicles also showed a slight but significant accumulation in rimb-1 mutant dendrites in the DA9 motor neuron (192 +/- 32% compared to wild type; N=15; P=.015). The sequence GC TAG C TAA A TGA (3 successive stop codons in different reading frames) was inserted after codon 16 of the rimb-1 gene; described in Edwards SL, et al. (manuscript in revision). Sentryn Acts with a Subset of Active Zone Proteins in the Guided Transport and Capture of Synaptic Vesicles in Caenorhabditis elegans.
Proper citation: RRID:WB-STRAIN:WBStrain00023504 Copy
http://www.wormbase.org/db/get?name=WBStrain00023505
Source Database: WormBase (WB)
Availability: available
Source References: PMID:37586371
Synonyms: ceIs308.
Alternate IDs: WB-STRAIN:KG5082, CGC_KG5082
Notes: ceIs308 [mig-13p::ins-22::Emerald + mig-13p::mCherry + odr-1p::RFP]; Linked to IVC (ceP86; 3.37): 0/17 recombinants. Expresses INS-22::Emerald to mark Dense Core Vesicles in the the DA9 and VA12 cholinergic motor neurons, and also mCherry in the same neurons to help identify the boundaries of the somas, axons, and dendrites. Useful for visualizing Dense Core Vesicles in a single, well-segregated neuron in living animals. When picking homozygotes from crosses with other strains, focus on the brightness of the RFP puncta in the cord. Autofluorescence in the worm body can make it difficult to gauge differences in brightness of the odr-1::RFP marker. Reference: Edwards SL, et al. (manuscript in revision). Sentryn Acts with a Subset of Active Zone Proteins in the Guided Transport and Capture of Synaptic Vesicles in Caenorhabditis elegans.|"Mutagen:Gamma Rays"|"Supplementary_genotype ceIS308 [Pmig-13::ins-22::Em, Pmig-13::RFPA]"
Proper citation: RRID:WB-STRAIN:WBStrain00023505 Copy
http://www.wormbase.org/db/get?name=WBStrain00023508
Source Database: WormBase (WB)
Affected Genes: WBGene00011279(asd-1)
Genomic Alteration: WBGene00011279(asd-1)
Availability: available
Synonyms: asd-1(yb978) III; ybIs733.
Alternate IDs: WB-STRAIN:KH1125, CGC_KH1125
Notes: ybIs733 [myo-3::egl-15::BGAR + lin-15(+)]. GFP/RFP chimeric expression of egl-15::BGAR reporter in body wall muscles.
Proper citation: RRID:WB-STRAIN:WBStrain00023508 Copy
http://www.wormbase.org/db/get?name=WBStrain00023506
Source Database: WormBase (WB)
Affected Genes: WBGene00006831(unc-104)|WBGene00012759(sup-1)
Genomic Alteration: WBGene00006831(unc-104), WBGene00012759(sup-1)
Availability: available
Synonyms: unc-104(ce833[5xMyc::AID::unc-104+sup-1(e995)]) II.
Alternate IDs: WB-STRAIN:KG5148, CGC_KG5148
Notes: The Auxin Inducible Degron (AID) flanked by a 5X Myc/spacer tag on left and a single spacer on the right is fused to the N-terminus of the unc-104 gene. Allows conditional degradation of UNC-104 protein when combined with tissue specific expression of TIR1 in the presence of 1 mM Auxin in plate media. Note: KG5148 does not express TIR1. On standard plates: wild type growth, appearance, and locomotion rate. For animals expressing a TIR1 transgene in the nervous system: Animals that hatch and develop on 1 mM Auxin plates generally remain tightly coiled near the location of hatching and exhibit slow growth (up to 7 days to reach adulthood, with 98% reaching adulthood by 7 days). Adults placed on Auxin abruptly lose about 75% of their locomotion function between 6 and 12 hours after plating. The remaining locomotion function is lost gradually between 12 and 52 hours. Reference: Stec N, et al. (Submitted). An Intron Compatible Marker for Long Distance CRISPR Mediated Gene Editing in Caenorhabditis elegans.
Proper citation: RRID:WB-STRAIN:WBStrain00023506 Copy
http://www.wormbase.org/db/get?name=WBStrain00023585
Source Database: WormBase (WB)
Affected Genes: WBGene00003917(par-2)
Genomic Alteration: WBGene00003917(par-2)
Availability: available
Source References: PMID:37729912, PMID:39652540
Synonyms: par-2(it315[mCherry::par-2]) III.
Alternate IDs: WB-STRAIN:KK1254, CGC_KK1254
Notes: par-2(it315) exhibits a weak maternal effect sterility, suggesting that the tag reduces the protein activity. Note, however, that double homozygous mutants of it315 with pkc-3(it309) or par-6(it310) exhibited partially penetrant and variable maternal effect lethality and maternal effect sterility that was stronger than it315 alone. Thus, although the GFP tags on pkc-3 and par-6 show no effect in an otherwise wild-type background, they do seem to somewhat compromise the activity of the proteins they tag. Made in N2 background.|"Supplementary_genotype par-2(it315[mCherry::par-2]) III"
Proper citation: RRID:WB-STRAIN:WBStrain00023585 Copy
http://www.wormbase.org/db/get?name=WBStrain00023588
Source Database: WormBase (WB)
Affected Genes: WBGene00000406(cdk-4)|WBGene00003056(lon-2)
Genomic Alteration: WBGene00000406(cdk-4), WBGene00003056(lon-2)
Availability: available
Source References: PMID:10518501
Synonyms: +/szT1 [lon-2(e678)] I; cdk-4(gv3)/szT1 X.
Alternate IDs: WB-STRAIN:KM48, CGC_KM48
Notes: 745 bp deletion of cdk-4 from intron I to exon3 removing putative ATP binding domain and catalytic residues. Most homozygous animals arrest at L2 due to absence of most or all postembryonic somatic cell divisions. Some germline proliferation resulting in slightly elongated gonad.|"Made_by: Brodigan & Krause"
Proper citation: RRID:WB-STRAIN:WBStrain00023588 Copy
http://www.wormbase.org/db/get?name=WBStrain00023586
Source Database: WormBase (WB)
Affected Genes: WBGene00003916(par-1)
Genomic Alteration: WBGene00003916(par-1)
Availability: available
Source References: PMID:33300872, PMID:39652540
Synonyms: par-1(it324[par-1::GFP::par-1 exon11a]) V.
Alternate IDs: WB-STRAIN:KK1262, CGC_KK1262
Notes: Superficially wild-type. Made in N2 background.|"WBStrain provided so WBPaper00060754 paper added based on AFP_Strain data."
Proper citation: RRID:WB-STRAIN:WBStrain00023586 Copy
http://www.wormbase.org/db/get?name=WBStrain00023537
Source Database: WormBase (WB)
Affected Genes: WBGene00000562(cng-1)|WBGene00000563(cng-3)|WBGene00006526(tax-4)
Genomic Alteration: WBGene00000562(cng-1), WBGene00000563(cng-3), WBGene00006526(tax-4)
Availability: available
Synonyms: tax-4(p678) III; cng-3(jh113) IV; cng-1(jh111) V.
Alternate IDs: WB-STRAIN:KJ5562, CGC_KJ5562
Notes: Made_by:
Proper citation: RRID:WB-STRAIN:WBStrain00023537 Copy
http://www.wormbase.org/db/get?name=WBStrain00023535
Source Database: WormBase (WB)
Affected Genes: WBGene00000562(cng-1)|WBGene00000563(cng-3)
Genomic Alteration: WBGene00000562(cng-1), WBGene00000563(cng-3)
Availability: available
Synonyms: cng-3(jh113) IV; cng-1(jh111) V.
Alternate IDs: WB-STRAIN:KJ5560, CGC_KJ5560
Notes: Made_by:
Proper citation: RRID:WB-STRAIN:WBStrain00023535 Copy
http://www.wormbase.org/db/get?name=WBStrain00023534
Source Database: WormBase (WB)
Affected Genes: WBGene00000562(cng-1)|WBGene00006526(tax-4)
Genomic Alteration: WBGene00000562(cng-1), WBGene00006526(tax-4)
Availability: available
Synonyms: tax-4(p678) III; cng-1(jh111) V.
Alternate IDs: WB-STRAIN:KJ5559, CGC_KJ5559
Notes: Made_by:
Proper citation: RRID:WB-STRAIN:WBStrain00023534 Copy
http://www.wormbase.org/db/get?name=WBStrain00023527
Source Database: WormBase (WB)
Affected Genes: WBGene00006527(tax-6)
Genomic Alteration: WBGene00006527(tax-6)
Availability: available
Synonyms: tax-6(jh107) IV.
Alternate IDs: WB-STRAIN:KJ306, CGC_KJ306
Notes: Gain-of-function mutant. Hypersensitive to serotonin.|"Mutagen:UV/TMP"
Proper citation: RRID:WB-STRAIN:WBStrain00023527 Copy
http://www.wormbase.org/db/get?name=WBStrain00023525
Source Database: WormBase (WB)
Affected Genes: WBGene00000802(crt-1)
Genomic Alteration: WBGene00000802(crt-1)
Availability: available
Source References: PMID:39519157
Synonyms: crt-1(jh101) V.
Alternate IDs: WB-STRAIN:KJ216, CGC_KJ216
Notes: Mutagen:UV/TMP
Proper citation: RRID:WB-STRAIN:WBStrain00023525 Copy
http://www.wormbase.org/db/get?name=WBStrain00023529
Source Database: WormBase (WB)
Affected Genes: WBGene00015062(trx-1)
Genomic Alteration: WBGene00015062(trx-1)
Availability: available
Source References: PMID:38446031
Synonyms: trx-1(jh127) II.
Alternate IDs: WB-STRAIN:KJ412, CGC_KJ412
Notes: Made_by Changhoon Ji|"Made_by: Changhoon Ji"|"Mutagen:UV/TMP"
Proper citation: RRID:WB-STRAIN:WBStrain00023529 Copy
http://www.wormbase.org/db/get?name=WBStrain00023559
Source Database: WormBase (WB)
Affected Genes: WBGene00001072(dpy-10)|WBGene00003196(mel-11)|WBGene00005016(sqt-1)|WBGene00006744(unc-4)|WBGene00006787(unc-52)
Genomic Alteration: WBGene00001072(dpy-10), WBGene00003196(mel-11), WBGene00005016(sqt-1), WBGene00006744(unc-4), WBGene00006787(unc-52)
Availability: available
Source References: PMID:3224814
Synonyms: mel-11(it26) unc-4(e120) sqt-1(sc13)/mnC1 [dpy-10(e128) unc-52(e444)] II.
Alternate IDs: WB-STRAIN:KK332, CGC_KK332
Notes: Heterozygotes are WT and segregate WT, DpyUnc, and UncRol (which give only dead eggs). Maintain by picking WT. mel-11 is not strict. See also WBPaper00002726.
Proper citation: RRID:WB-STRAIN:WBStrain00023559 Copy
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